| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| JMJD1C | jumonji domain containing 1C | 0.0846169 |
| RPS2 | ribosomal protein S2 | 0.0668658 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0590487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0567062 |
| MT2A | metallothionein 2A | 0.0541302 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0527476 |
| ZFP36 | ZFP36 ring finger protein | 0.0478262 |
| TXNRD1 | thioredoxin reductase 1 | 0.0474507 |
| ARRDC3 | arrestin domain containing 3 | 0.0468061 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0464707 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0455343 |
| SNX14 | sorting nexin 14 | 0.0430035 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0418093 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0415466 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0405427 |
| ZNF292 | zinc finger protein 292 | 0.0404941 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0398182 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.039699 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0394553 |
| GOLGA4 | golgin A4 | 0.0382424 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0380819 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0375322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0373607 |
| XPO1 | exportin 1 | 0.0373399 |
| USP3 | ubiquitin specific peptidase 3 | 0.0368175 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0356555 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0351873 |
| AFDN | afadin, adherens junction formation factor | 0.0351611 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0347116 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347098 |
| MED13L | mediator complex subunit 13-like | 0.0338113 |
| SMAD3 | SMAD family member 3 | 0.0336691 |
| RNF145 | ring finger protein 145 | 0.0334799 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0332908 |
| NOP58 | NOP58 ribonucleoprotein | 0.0331851 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0327887 |
| OGA | O-GlcNAcase | 0.0323079 |
| PUM2 | pumilio RNA-binding family member 2 | 0.032288 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0320713 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0310124 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0308192 |
| PCBP2 | poly(rC) binding protein 2 | 0.0307787 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0305385 |
| SPAG9 | sperm associated antigen 9 | 0.0304735 |
| SET | SET nuclear proto-oncogene | 0.0303871 |
| MATR3 | matrin 3 | 0.0302735 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.030163 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.030146 |
| FMNL2 | formin-like 2 | 0.0295433 |
| ANO6 | anoctamin 6 | 0.029153 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0290721 |
| SEPTIN9 | septin 9 | 0.0287804 |
| B2M | beta-2-microglobulin | 0.0286941 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0286491 |
| CCNL1 | cyclin L1 | 0.028445 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0283631 |
| SFTPA2 | surfactant protein A2 | 0.0275751 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0275227 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0275006 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0274907 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0272962 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0271405 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0268274 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0264284 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0263533 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0262935 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0262542 |
| RPS3 | ribosomal protein S3 | 0.0262004 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0261645 |
| PHIP | pleckstrin homology domain interacting protein | 0.025995 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258691 |
| NUP58 | nucleoporin 58 | 0.0255767 |
| RPS12 | ribosomal protein S12 | 0.0255476 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0254554 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0249386 |
| YAP1 | Yes-associated protein 1 | 0.0248966 |
| FOSL1 | FOS-like antigen 1 | 0.0247595 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0246632 |
| PDE8A | phosphodiesterase 8A | 0.0245879 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.024272 |
| RLF | rearranged L-myc fusion | 0.0242686 |
| MYOF | myoferlin | 0.024188 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0241353 |
| MSN | moesin | 0.0241073 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0239313 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0238669 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0238546 |
| TPD52 | tumor protein D52 | 0.0237254 |
| RBM39 | RNA binding motif protein 39 | 0.0233856 |
| FOXO3 | forkhead box O3 | 0.0233347 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0232355 |
| NUP153 | nucleoporin 153kDa | 0.0231743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0228066 |
| ADM | adrenomedullin | 0.0226872 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0226151 |
| CALU | calumenin | 0.022461 |
| BRD2 | bromodomain containing 2 | 0.0220639 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0220433 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0219858 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0219314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.273471 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.212269 |
| AHNAK | AHNAK nucleoprotein | -0.114191 |
| VCL | vinculin | -0.0938527 |
| MKI67 | marker of proliferation Ki-67 | -0.0933545 |
| RPL35A | ribosomal protein L35a | -0.09128 |
| TMSB10 | thymosin beta 10 | -0.079857 |
| RPS16 | ribosomal protein S16 | -0.0711146 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0617743 |
| EGFR | epidermal growth factor receptor | -0.0577826 |
| DST | dystonin | -0.0535542 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0464843 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0463237 |
| EGR1 | early growth response 1 | -0.0461717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.04602 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.04127 |
| HMGA2 | high mobility group AT-hook 2 | -0.0401889 |
| DIAPH2 | diaphanous-related formin 2 | -0.0366933 |
| RPS24 | ribosomal protein S24 | -0.036691 |
| ATG7 | autophagy related 7 | -0.0353921 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0344082 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0342651 |
| CARD18 | caspase recruitment domain family, member 18 | -0.033388 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0320399 |
| CENPE | centromere protein E, 312kDa | -0.0319229 |
| EHBP1 | EH domain binding protein 1 | -0.0303013 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.03023 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.029401 |
| KRT8 | keratin 8, type II | -0.0287917 |
| CTSD | cathepsin D | -0.0275637 |
| INTS6 | integrator complex subunit 6 | -0.0271879 |
| MAP1B | microtubule-associated protein 1B | -0.0264236 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0263352 |
| ACTG1 | actin gamma 1 | -0.0257824 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0256288 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0253309 |
| MCL1 | myeloid cell leukemia 1 | -0.0250738 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0248852 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0245739 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0242199 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0240565 |
| ZNF780B | zinc finger protein 780B | -0.0239436 |
| MYO1E | myosin IE | -0.023239 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0230741 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0227318 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0222336 |
| CDK13 | cyclin-dependent kinase 13 | -0.0218002 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0217635 |
| RASAL2 | RAS protein activator like 2 | -0.0217471 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0216691 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0215637 |
| PRSS23 | protease, serine, 23 | -0.0215215 |
| GNAS | GNAS complex locus | -0.0214706 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0213577 |
| FTL | ferritin, light polypeptide | -0.0210417 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0209248 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0208939 |
| CENPF | centromere protein F, 350/400kDa | -0.0205841 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0204731 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.0203915 |
| RBMX | RNA binding motif protein, X-linked | -0.0199523 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0197518 |
| RPL34 | ribosomal protein L34 | -0.0193864 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0193248 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0192376 |
| CUX1 | cut-like homeobox 1 | -0.0191972 |
| DEK | DEK proto-oncogene | -0.0191569 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | -0.0191163 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0186295 |
| RPLP1 | ribosomal protein, large, P1 | -0.0184102 |
| ZYX | zyxin | -0.0181562 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0177932 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0175831 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0173821 |
| R3HDM2 | R3H domain containing 2 | -0.0173223 |
| RPS29 | ribosomal protein S29 | -0.0172674 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0172387 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0169933 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0169471 |
| RPL23 | ribosomal protein L23 | -0.0168059 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0167619 |
| RPLP2 | ribosomal protein, large, P2 | -0.016652 |
| TPM1 | tropomyosin 1 (alpha) | -0.016531 |
| NABP1 | nucleic acid binding protein 1 | -0.0165002 |
| AK6 | adenylate kinase 6 | -0.0164843 |
| RPL10A | ribosomal protein L10a | -0.0163997 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0162847 |
| RPL37A | ribosomal protein L37a | -0.0161393 |
| RPS27A | ribosomal protein S27a | -0.0160288 |
| PLIN2 | perilipin 2 | -0.0156967 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0155388 |
| ATF7 | activating transcription factor 7 | -0.0155295 |
| BRI3BP | BRI3 binding protein | -0.0153697 |
| CAVIN1 | caveolae associated protein 1 | -0.0153616 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.015354 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0153106 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0152759 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0152654 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0152367 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0151573 |
