| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.166431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0906767 |
| RPS2 | ribosomal protein S2 | 0.0897277 |
| ACTG1 | actin gamma 1 | 0.0846879 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0653246 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.053526 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0515625 |
| GOLGA4 | golgin A4 | 0.0487736 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.046814 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0451686 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0438661 |
| NUP58 | nucleoporin 58 | 0.0429912 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0426058 |
| JMJD1C | jumonji domain containing 1C | 0.0414492 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0411064 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0404697 |
| MTDH | metadherin | 0.0400992 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0386862 |
| OGA | O-GlcNAcase | 0.0372197 |
| RASA2 | RAS p21 protein activator 2 | 0.036786 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0367296 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0345872 |
| CAPRIN2 | caprin family member 2 | 0.0343996 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0340602 |
| RPL7 | ribosomal protein L7 | 0.0333892 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0333215 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.033174 |
| CLTC | clathrin, heavy chain (Hc) | 0.0331038 |
| TMF1 | TATA element modulatory factor 1 | 0.032955 |
| RPL3 | ribosomal protein L3 | 0.032749 |
| SEC24D | SEC24 family member D | 0.0325294 |
| WDR26 | WD repeat domain 26 | 0.0321732 |
| CALU | calumenin | 0.0321603 |
| GOLT1B | golgi transport 1B | 0.0318436 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0318042 |
| LAMB3 | laminin, beta 3 | 0.0315697 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.031406 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0311866 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.029896 |
| TUT7 | terminal uridylyl transferase 7 | 0.0297323 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296482 |
| ARFGEF3 | ARFGEF family member 3 | 0.0296278 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0293119 |
| RBM39 | RNA binding motif protein 39 | 0.0292618 |
| TEX10 | testis expressed 10 | 0.0290791 |
| TXNRD1 | thioredoxin reductase 1 | 0.0289997 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0287226 |
| SET | SET nuclear proto-oncogene | 0.0284917 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283022 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0280829 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0280476 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0280031 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0279992 |
| RLF | rearranged L-myc fusion | 0.0269879 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0266855 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0265322 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0265123 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0261264 |
| TMEM156 | transmembrane protein 156 | 0.0260243 |
| ANXA5 | annexin A5 | 0.0259616 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0259574 |
| FOXJ3 | forkhead box J3 | 0.025957 |
| SPAG9 | sperm associated antigen 9 | 0.0257546 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0255157 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0252864 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0250074 |
| SUCO | SUN domain containing ossification factor | 0.0247758 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0247145 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0246222 |
| PGM3 | phosphoglucomutase 3 | 0.0242267 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0242038 |
| TPD52 | tumor protein D52 | 0.0234972 |
| GOLGA2 | golgin A2 | 0.0233888 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0230872 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0230132 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0229012 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0228149 |
| PAPOLA | poly(A) polymerase alpha | 0.0227407 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0225024 |
| SNX9 | sorting nexin 9 | 0.0223325 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.0221256 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0220847 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0220467 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0220228 |
| NCKAP1 | NCK-associated protein 1 | 0.0219482 |
| NKTR | natural killer cell triggering receptor | 0.021894 |
| DENR | density-regulated protein | 0.0218332 |
| ZNF160 | zinc finger protein 160 | 0.0217822 |
| RPS18 | ribosomal protein S18 | 0.0217265 |
| RNF24 | ring finger protein 24 | 0.0216732 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0214384 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.021414 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0213981 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0212872 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0211172 |
| CANX | calnexin | 0.0210657 |
| CDK17 | cyclin-dependent kinase 17 | 0.0210137 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0209241 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0207128 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.020678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.149138 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.129894 |
| ZNF438 | zinc finger protein 438 | -0.118158 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.112531 |
| HMGA2 | high mobility group AT-hook 2 | -0.103151 |
| RPL35A | ribosomal protein L35a | -0.0925615 |
| FRMD6 | FERM domain containing 6 | -0.0915912 |
| BNC2 | basonuclin 2 | -0.0863458 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0862491 |
| TTR | transthyretin | -0.081885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0813609 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0789649 |
| NABP1 | nucleic acid binding protein 1 | -0.0786729 |
| MTAP | methylthioadenosine phosphorylase | -0.0680421 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0655433 |
| TMSB10 | thymosin beta 10 | -0.0651497 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0599778 |
| FLNB | filamin B, beta | -0.0598874 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.058683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0549328 |
| RAD51B | RAD51 paralog B | -0.0547428 |
| NAV2 | neuron navigator 2 | -0.0543671 |
| AHNAK | AHNAK nucleoprotein | -0.0518368 |
| FHIT | fragile histidine triad | -0.0507631 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0500627 |
| ASPH | aspartate beta-hydroxylase | -0.0493534 |
| DIAPH3 | diaphanous-related formin 3 | -0.0483033 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0477764 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0473441 |
| EXOC4 | exocyst complex component 4 | -0.0460175 |
| RPLP1 | ribosomal protein, large, P1 | -0.0435826 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0425172 |
| PFN1 | profilin 1 | -0.0420918 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0417961 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0413316 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0408828 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0408695 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0406589 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.040586 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0388922 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0387903 |
| DIAPH2 | diaphanous-related formin 2 | -0.0385057 |
| NAV3 | neuron navigator 3 | -0.038331 |
| DENND1A | DENN/MADD domain containing 1A | -0.0377188 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0377076 |
| SP100 | SP100 nuclear antigen | -0.0366787 |
| CDK6 | cyclin-dependent kinase 6 | -0.0365965 |
| ANK2 | ankyrin 2, neuronal | -0.0350391 |
| PTMA | prothymosin, alpha | -0.034643 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0345398 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0343023 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0342239 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0341032 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0332459 |
| RPS19 | ribosomal protein S19 | -0.0326789 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0325021 |
| RPS24 | ribosomal protein S24 | -0.0324898 |
| PGK1 | phosphoglycerate kinase 1 | -0.0304675 |
| RPS21 | ribosomal protein S21 | -0.030387 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0303309 |
| TCF12 | transcription factor 12 | -0.0301086 |
| RPL23 | ribosomal protein L23 | -0.0298947 |
| EFNB2 | ephrin-B2 | -0.029815 |
| FOXP1 | forkhead box P1 | -0.0296963 |
| PHF14 | PHD finger protein 14 | -0.029661 |
| TBC1D5 | TBC1 domain family, member 5 | -0.028976 |
| CALD1 | caldesmon 1 | -0.0287994 |
| RIGI | RNA sensor RIG-I | -0.0285876 |
| CUX1 | cut-like homeobox 1 | -0.0283301 |
| CCDC91 | coiled-coil domain containing 91 | -0.028215 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0281088 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0276832 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0276363 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0274855 |
| RAB3IP | RAB3A interacting protein | -0.0274427 |
| RASAL2 | RAS protein activator like 2 | -0.0273486 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0273295 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0270559 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0270361 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0267106 |
| SMYD3 | SET and MYND domain containing 3 | -0.0264115 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0260443 |
| RNF213 | ring finger protein 213 | -0.0259123 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0256393 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0254944 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0252346 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0250388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0247328 |
| PARD3 | par-3 family cell polarity regulator | -0.0244999 |
| RPL34 | ribosomal protein L34 | -0.0242312 |
| S100A2 | S100 calcium binding protein A2 | -0.0240276 |
| AEBP2 | AE binding protein 2 | -0.0236605 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0236525 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0235615 |
| CNTLN | centlein, centrosomal protein | -0.0234547 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0231794 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0230416 |
| TUBB | tubulin, beta class I | -0.0229612 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0228657 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.022823 |
