| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0909954 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0818641 |
| GOLGA4 | golgin A4 | 0.067818 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0658356 |
| ATP13A3 | ATPase type 13A3 | 0.0648746 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0633655 |
| CD109 | CD109 molecule | 0.0511303 |
| B2M | beta-2-microglobulin | 0.0503658 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0481368 |
| VEGFA | vascular endothelial growth factor A | 0.0458303 |
| FNIP1 | folliculin interacting protein 1 | 0.0439107 |
| NGLY1 | N-glycanase 1 | 0.041447 |
| SETD5 | SET domain containing 5 | 0.0410019 |
| TMF1 | TATA element modulatory factor 1 | 0.0395988 |
| YEATS2 | YEATS domain containing 2 | 0.0387354 |
| XPO1 | exportin 1 | 0.0380333 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0355445 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0344935 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0340165 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0332933 |
| NAV2 | neuron navigator 2 | 0.0332531 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0312442 |
| ARRDC3 | arrestin domain containing 3 | 0.0310958 |
| OPTN | optineurin | 0.0309608 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.030607 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0303049 |
| SETD2 | SET domain containing 2 | 0.0299247 |
| CDCP1 | CUB domain containing protein 1 | 0.0298945 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0296436 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0295091 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0293929 |
| ITSN2 | intersectin 2 | 0.0286125 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0281677 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0273732 |
| DENND4C | DENN/MADD domain containing 4C | 0.0272741 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0272314 |
| ADM | adrenomedullin | 0.0271878 |
| MMP12 | matrix metallopeptidase 12 | 0.0268734 |
| NCKAP1 | NCK-associated protein 1 | 0.0267645 |
| ZNF292 | zinc finger protein 292 | 0.026691 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0266761 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.026593 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0261424 |
| SFXN1 | sideroflexin 1 | 0.0257895 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0256953 |
| PHF3 | PHD finger protein 3 | 0.0256594 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0256549 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0247425 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0247172 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0246801 |
| TPM3 | tropomyosin 3 | 0.0245424 |
| PGK1 | phosphoglycerate kinase 1 | 0.0245372 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0242611 |
| CEP95 | centrosomal protein 95kDa | 0.0239503 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0239403 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0238681 |
| HELZ | helicase with zinc finger | 0.0237281 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0236502 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0231085 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0230529 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0227999 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0226884 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226603 |
| MATR3 | matrin 3 | 0.022622 |
| AXL | AXL receptor tyrosine kinase | 0.022392 |
| IL6ST | interleukin 6 signal transducer | 0.0222482 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0221691 |
| CDON | cell adhesion associated, oncogene regulated | 0.0221352 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0220003 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0219778 |
| FOSL1 | FOS-like antigen 1 | 0.0218975 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0218671 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212373 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0211143 |
| ZNF654 | zinc finger protein 654 | 0.0210226 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0210144 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0209517 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0209117 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0207236 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0205014 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0204663 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0204037 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0203684 |
| MSN | moesin | 0.0202298 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0201969 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0200837 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0198853 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0198755 |
| PREPL | prolyl endopeptidase-like | 0.0198457 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0197069 |
| OGA | O-GlcNAcase | 0.0196795 |
| RAB6A | RAB6A, member RAS oncogene family | 0.01966 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0196099 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0196034 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.019564 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0195569 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0194824 |
| ATRN | attractin | 0.0194503 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0193313 |
| CDC73 | cell division cycle 73 | 0.0192541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.277897 |
| VIM | vimentin | -0.178235 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.132682 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.127488 |
| COL1A1 | collagen, type I, alpha 1 | -0.124941 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.124433 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114673 |
| CDH13 | cadherin 13 | -0.113128 |
| COL1A2 | collagen, type I, alpha 2 | -0.0970124 |
| TMSB10 | thymosin beta 10 | -0.0953222 |
| FRMD4A | FERM domain containing 4A | -0.0841547 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0823767 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0758717 |
| EGR1 | early growth response 1 | -0.0749144 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0736609 |
| EXT1 | exostosin glycosyltransferase 1 | -0.073488 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0719291 |
| COL5A1 | collagen, type V, alpha 1 | -0.0678393 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0657142 |
| GLIS3 | GLIS family zinc finger 3 | -0.0640735 |
| IL1B | interleukin 1, beta | -0.0635544 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0589188 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0545834 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0543751 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0520621 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0512479 |
| INHBA | inhibin, beta A | -0.0499723 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.049622 |
| TNNC1 | troponin C type 1 (slow) | -0.0476275 |
| POTEF | POTE ankyrin domain family, member F | -0.0456341 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0453939 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0449249 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0445719 |
| NAV1 | neuron navigator 1 | -0.0435807 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0432805 |
| ASPH | aspartate beta-hydroxylase | -0.043219 |
| TMEM178B | transmembrane protein 178B | -0.0406203 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0397474 |
| TNS3 | tensin 3 | -0.0393646 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0390088 |
| SP100 | SP100 nuclear antigen | -0.0388113 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0380627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0369317 |
| TPM1 | tropomyosin 1 (alpha) | -0.0367706 |
| IER3 | immediate early response 3 | -0.0363909 |
| EGFR | epidermal growth factor receptor | -0.0362189 |
| TPM4 | tropomyosin 4 | -0.0360257 |
| AHNAK | AHNAK nucleoprotein | -0.0360126 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0359323 |
| RAD51B | RAD51 paralog B | -0.0356052 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0348028 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0339677 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0337758 |
| INTS6 | integrator complex subunit 6 | -0.0336016 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0330845 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0329849 |
| NDRG1 | N-myc downstream regulated 1 | -0.0327758 |
| VCAN | versican | -0.0326721 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0325234 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0322918 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0321791 |
| RIGI | RNA sensor RIG-I | -0.0320792 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0319343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0316874 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0312258 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0306646 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.029312 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0290433 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0289773 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289301 |
| FBXO11 | F-box protein 11 | -0.0288858 |
| HDLBP | high density lipoprotein binding protein | -0.0285248 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0284585 |
| ACTG1 | actin gamma 1 | -0.0283334 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0281211 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0279402 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0278867 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0277437 |
| DNER | delta/notch-like EGF repeat containing | -0.0268466 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0262794 |
| NRP1 | neuropilin 1 | -0.0262465 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0260554 |
| ATG7 | autophagy related 7 | -0.02592 |
| NABP1 | nucleic acid binding protein 1 | -0.025898 |
| POU2F2 | POU class 2 homeobox 2 | -0.0257252 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0256702 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0255913 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.025429 |
| TMEM263 | transmembrane protein 263 | -0.0253685 |
| FBN1 | fibrillin 1 | -0.0252786 |
| TGFB1 | transforming growth factor, beta 1 | -0.0250417 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0250107 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0247387 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0246673 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0246285 |
| MCL1 | myeloid cell leukemia 1 | -0.0245206 |
| GNAS | GNAS complex locus | -0.0243919 |
| RND3 | Rho family GTPase 3 | -0.0243087 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0242596 |
| VCL | vinculin | -0.0240308 |
