| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.082465 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0692606 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0674688 |
| CPE | carboxypeptidase E | 0.0644999 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0540947 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0515093 |
| STC1 | stanniocalcin 1 | 0.0493205 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0425279 |
| CHGB | chromogranin B | 0.0414542 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0411078 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0401477 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0394705 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0393332 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0389729 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0348004 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0332984 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0318045 |
| NCKAP5 | NCK-associated protein 5 | 0.0307069 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0292731 |
| AHR | aryl hydrocarbon receptor | 0.0267803 |
| DST | dystonin | 0.0263806 |
| SIK2 | salt-inducible kinase 2 | 0.0252698 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.023439 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0231702 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0229212 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.022131 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.021976 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0219529 |
| MSN | moesin | 0.0218448 |
| FMNL2 | formin-like 2 | 0.0217697 |
| ENO1 | enolase 1, (alpha) | 0.0216567 |
| DUSP10 | dual specificity phosphatase 10 | 0.0209505 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0205932 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0204555 |
| GPRIN3 | GPRIN family member 3 | 0.0197894 |
| RAB30 | RAB30, member RAS oncogene family | 0.0197754 |
| SVIL | supervillin | 0.0197277 |
| SP140L | SP140 nuclear body protein-like | 0.0197074 |
| MCL1 | myeloid cell leukemia 1 | 0.0189342 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0187412 |
| TOP1 | topoisomerase (DNA) I | 0.0184749 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0181088 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0180078 |
| NAV1 | neuron navigator 1 | 0.0178388 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0176325 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0174009 |
| ERBIN | erbb2 interacting protein | 0.0173719 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0172734 |
| TOX | thymocyte selection-associated high mobility group box | 0.0171122 |
| NRP1 | neuropilin 1 | 0.0170404 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0168122 |
| PGK1 | phosphoglycerate kinase 1 | 0.016672 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0164176 |
| SCG2 | secretogranin II | 0.016058 |
| VEGFA | vascular endothelial growth factor A | 0.0158724 |
| FBXO11 | F-box protein 11 | 0.0158644 |
| NRG1 | neuregulin 1 | 0.0156126 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0155864 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0153227 |
| RIT2 | Ras-like without CAAX 2 | 0.015265 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0150545 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0149419 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0148889 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.014815 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0147061 |
| SMAD3 | SMAD family member 3 | 0.0144733 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0144262 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.0144208 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0144198 |
| NUP188 | nucleoporin 188kDa | 0.0143907 |
| RBBP8 | retinoblastoma binding protein 8 | 0.0143461 |
| GRAMD1B | GRAM domain containing 1B | 0.0141565 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0141499 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0140645 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.013984 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0139091 |
| MTSS1 | metastasis suppressor 1 | 0.0138925 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0138821 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0135797 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0135166 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.013486 |
| TMEM65 | transmembrane protein 65 | 0.0133461 |
| AOPEP | aminopeptidase O (putative) | 0.0132516 |
| TCP1 | t-complex 1 | 0.013186 |
| ELMO1 | engulfment and cell motility 1 | 0.0131028 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0130941 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0130336 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0130056 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0129883 |
| KLHL8 | kelch-like family member 8 | 0.0128633 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0128531 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0128245 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0128037 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.0127917 |
| RHOQ | ras homolog family member Q | 0.0127777 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 | 0.0127618 |
| ANXA5 | annexin A5 | 0.012759 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0126692 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0126327 |
| INHBA | inhibin, beta A | 0.0125591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.134963 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.106179 |
| TENM1 | teneurin transmembrane protein 1 | -0.103517 |
| CENPF | centromere protein F, 350/400kDa | -0.0989031 |
| SNTG1 | syntrophin, gamma 1 | -0.0864445 |
| GPC6 | glypican 6 | -0.0797569 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0762496 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0694954 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0593186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0574999 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0524102 |
| CALCA | calcitonin-related polypeptide alpha | -0.0523239 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0515573 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0496821 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.049297 |
| MKI67 | marker of proliferation Ki-67 | -0.0492881 |
| SYT1 | synaptotagmin I | -0.048603 |
| GPC5 | glypican 5 | -0.0473283 |
| PCBP3 | poly(rC) binding protein 3 | -0.0451575 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0440751 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0429018 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0415176 |
| DTNA | dystrobrevin, alpha | -0.0412339 |
| MAP1B | microtubule-associated protein 1B | -0.0399663 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.038494 |
| RPS21 | ribosomal protein S21 | -0.0384588 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0378952 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377374 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.037627 |
| GPHN | gephyrin | -0.0376241 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0376113 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0375967 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0375931 |
| RPL26 | ribosomal protein L26 | -0.0370476 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0369793 |
| IRS2 | insulin receptor substrate 2 | -0.0367656 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0365673 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.036551 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.035395 |
| NFIA | nuclear factor I/A | -0.0349059 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.034555 |
| SMYD3 | SET and MYND domain containing 3 | -0.0339808 |
| GNAS | GNAS complex locus | -0.0339466 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0335823 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0331691 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0330872 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0329026 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0329016 |
| PTCHD4 | patched domain containing 4 | -0.0324483 |
| NLGN1 | neuroligin 1 | -0.0319124 |
| ZNF292 | zinc finger protein 292 | -0.0312839 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0311983 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0310352 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0310025 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0307438 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.030594 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.030437 |
| NKTR | natural killer cell triggering receptor | -0.0304306 |
| STXBP5L | syntaxin binding protein 5-like | -0.0303452 |
| CA8 | carbonic anhydrase VIII | -0.030218 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0302071 |
| KNL1 | kinetochore scaffold 1 | -0.0299564 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0296245 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.029624 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0293364 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.029241 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.029109 |
| MED13L | mediator complex subunit 13-like | -0.028944 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0286868 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0285648 |
| RPL8 | ribosomal protein L8 | -0.0285167 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0282948 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0278811 |
| TPX2 | TPX2, microtubule-associated | -0.0278799 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0271529 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0270899 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0270663 |
| RPL34 | ribosomal protein L34 | -0.0269447 |
| RGS7 | regulator of G-protein signaling 7 | -0.0269223 |
| DENND4A | DENN/MADD domain containing 4A | -0.0269082 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267974 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264637 |
| LSAMP | limbic system-associated membrane protein | -0.0262578 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.026237 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0261053 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0260537 |
| RLF | rearranged L-myc fusion | -0.0259026 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.02585 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0257544 |
| MSI2 | musashi RNA-binding protein 2 | -0.0257041 |
| KIAA1958 | KIAA1958 | -0.0254342 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.025348 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0252872 |
| ECT2 | epithelial cell transforming 2 | -0.0251386 |
| ANLN | anillin, actin binding protein | -0.0246309 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0245536 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0245508 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0244915 |
| DENND1A | DENN/MADD domain containing 1A | -0.0244837 |
| KLHL29 | kelch-like family member 29 | -0.0244548 |
