| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.188073 |
| PTMA | prothymosin, alpha | 0.134899 |
| PKM | pyruvate kinase, muscle | 0.115785 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.114347 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.105323 |
| AHNAK | AHNAK nucleoprotein | 0.0903524 |
| BMP10 | bone morphogenetic protein 10 | 0.0830905 |
| RPS6 | ribosomal protein S6 | 0.0785366 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0743775 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0697179 |
| ENO1 | enolase 1, (alpha) | 0.0676794 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0650774 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0635998 |
| RPS8 | ribosomal protein S8 | 0.0629587 |
| UBC | ubiquitin C | 0.0617717 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0613473 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0574977 |
| TJP1 | tight junction protein 1 | 0.0535576 |
| HDAC9 | histone deacetylase 9 | 0.0521427 |
| RPS27A | ribosomal protein S27a | 0.0499807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0496597 |
| MKI67 | marker of proliferation Ki-67 | 0.0478845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0478481 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0468368 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0455844 |
| LOC112694756 | uncharaterized LOC112694756 | 0.044045 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0438982 |
| TMSB4X | thymosin beta 4, X-linked | 0.0431813 |
| TPM4 | tropomyosin 4 | 0.0429503 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0422508 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0413789 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0409611 |
| LOXL3 | lysyl oxidase-like 3 | 0.0405595 |
| RPLP1 | ribosomal protein, large, P1 | 0.0389018 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0384035 |
| PRDX2 | peroxiredoxin 2 | 0.0377639 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037702 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0374494 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0374308 |
| LDHB | lactate dehydrogenase B | 0.036756 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0363066 |
| ACTG1 | actin gamma 1 | 0.035985 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0357968 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0356648 |
| MATR3 | matrin 3 | 0.0356336 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0355829 |
| S100A4 | S100 calcium binding protein A4 | 0.0351057 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0346753 |
| FAT1 | FAT atypical cadherin 1 | 0.0344686 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0339215 |
| RPL31 | ribosomal protein L31 | 0.0335876 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0335827 |
| POTEF | POTE ankyrin domain family, member F | 0.0329354 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0327134 |
| RPL23 | ribosomal protein L23 | 0.0321592 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0318134 |
| RPL13A | ribosomal protein L13a | 0.0314807 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0308135 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0307009 |
| LDHA | lactate dehydrogenase A | 0.0302124 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0301103 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0297928 |
| AMOTL2 | angiomotin like 2 | 0.0295106 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0292714 |
| RPLP0 | ribosomal protein, large, P0 | 0.0292052 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0291673 |
| S100A6 | S100 calcium binding protein A6 | 0.0285814 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284016 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281717 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0278764 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0278 |
| CORO1C | coronin, actin binding protein, 1C | 0.0277668 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0276908 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0271077 |
| GNAS | GNAS complex locus | 0.0270196 |
| TXNIP | thioredoxin interacting protein | 0.0266896 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261852 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0258607 |
| RPL8 | ribosomal protein L8 | 0.0256511 |
| RPL4 | ribosomal protein L4 | 0.02564 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0255344 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.024854 |
| TRERF1 | transcriptional regulating factor 1 | 0.02479 |
| RHOA | ras homolog family member A | 0.0245264 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0243537 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0238903 |
| FBLN2 | fibulin 2 | 0.0238686 |
| VMP1 | vacuole membrane protein 1 | 0.0237806 |
| RPLP2 | ribosomal protein, large, P2 | 0.0237641 |
| ONECUT2 | one cut homeobox 2 | 0.0237509 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0237316 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0237278 |
| PFN1 | profilin 1 | 0.0236034 |
| HDLBP | high density lipoprotein binding protein | 0.0233084 |
| APP | amyloid beta (A4) precursor protein | 0.0232973 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0232074 |
| EVI5 | ecotropic viral integration site 5 | 0.0231989 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0231361 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0230879 |
| DEK | DEK proto-oncogene | 0.0226662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.126724 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.077929 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0591851 |
| PRELID2 | PRELI domain containing 2 | -0.0589651 |
| TXNRD1 | thioredoxin reductase 1 | -0.0555388 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0455697 |
| SMYD3 | SET and MYND domain containing 3 | -0.0449831 |
| RTN4 | reticulon 4 | -0.0446328 |
| GPHN | gephyrin | -0.0442499 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0440481 |
| ANK2 | ankyrin 2, neuronal | -0.0407638 |
| DUSP4 | dual specificity phosphatase 4 | -0.0389245 |
| GLI2 | GLI family zinc finger 2 | -0.0388598 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0370891 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0365921 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0359989 |
| SQSTM1 | sequestosome 1 | -0.0351754 |
| FLNB | filamin B, beta | -0.0341387 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0331113 |
| JMJD1C | jumonji domain containing 1C | -0.0322816 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0322654 |
| DENND4A | DENN/MADD domain containing 4A | -0.0319121 |
| NF1 | neurofibromin 1 | -0.0318744 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.031846 |
| MEF2A | myocyte enhancer factor 2A | -0.0316967 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0313883 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0308531 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0306502 |
| TMEM41B | transmembrane protein 41B | -0.0293341 |
| RBM39 | RNA binding motif protein 39 | -0.0290598 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0282836 |
| ZNF217 | zinc finger protein 217 | -0.0277569 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0276982 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.027694 |
| TCF12 | transcription factor 12 | -0.0276165 |
| SPAG9 | sperm associated antigen 9 | -0.0272338 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0270495 |
| RFX7 | regulatory factor X, 7 | -0.0269121 |
| TMEM14B | transmembrane protein 14B | -0.0266581 |
| PLPP3 | phospholipid phosphatase 3 | -0.0264 |
| RUNX1 | runt-related transcription factor 1 | -0.0260495 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0258867 |
| DYM | dymeclin | -0.0258355 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0257322 |
| EGFR | epidermal growth factor receptor | -0.0256307 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0253723 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0248349 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248026 |
| TBC1D5 | TBC1 domain family, member 5 | -0.024796 |
| NBEA | neurobeachin | -0.0246456 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0246323 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0245945 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0245259 |
| TRIM44 | tripartite motif containing 44 | -0.0239651 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0236871 |
| ATP9B | ATPase, class II, type 9B | -0.0232672 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -0.0231904 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0231678 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0231245 |
| DENND1A | DENN/MADD domain containing 1A | -0.0231084 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0229431 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0229077 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.022509 |
| SPIDR | scaffolding protein involved in DNA repair | -0.022502 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0224028 |
| TMEM65 | transmembrane protein 65 | -0.0223309 |
| TSC22D2 | TSC22 domain family, member 2 | -0.022095 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0218466 |
| HJURP | Holliday junction recognition protein | -0.021845 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0213396 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0213319 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0210917 |
| CLTC | clathrin, heavy chain (Hc) | -0.0209345 |
| NBAS | neuroblastoma amplified sequence | -0.0209327 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0208439 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0207042 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0206696 |
| ANO6 | anoctamin 6 | -0.0205698 |
| COMMD10 | COMM domain containing 10 | -0.0204397 |
| MEMO1 | mediator of cell motility 1 | -0.0203758 |
| TPD52 | tumor protein D52 | -0.0201784 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.020091 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0199919 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0199863 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0199403 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.019916 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0199007 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0198402 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.019793 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0196703 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0196139 |
| HMBOX1 | homeobox containing 1 | -0.0195777 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0194781 |
| RAB28 | RAB28, member RAS oncogene family | -0.0194072 |
| OSMR | oncostatin M receptor | -0.0193318 |
| RPL21 | ribosomal protein L21 | -0.0192768 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0191975 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0190697 |
| COG5 | component of oligomeric golgi complex 5 | -0.0190426 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0189507 |
