| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.171075 |
| VEGFA | vascular endothelial growth factor A | 0.135219 |
| PDE10A | phosphodiesterase 10A | 0.129383 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.123151 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.117418 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.107011 |
| ADM | adrenomedullin | 0.10623 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.10612 |
| NDRG1 | N-myc downstream regulated 1 | 0.0938589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0890536 |
| GOLGA4 | golgin A4 | 0.0872437 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0846169 |
| RPS6 | ribosomal protein S6 | 0.0805016 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.075813 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0718811 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0688196 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0687556 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0673768 |
| MSN | moesin | 0.0672765 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0661473 |
| SFTPA2 | surfactant protein A2 | 0.065651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0648094 |
| STC1 | stanniocalcin 1 | 0.064033 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.059703 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0584541 |
| VCAN | versican | 0.0580029 |
| ATP13A3 | ATPase type 13A3 | 0.0578061 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0553867 |
| RPS2 | ribosomal protein S2 | 0.0543373 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0542556 |
| NGLY1 | N-glycanase 1 | 0.0535006 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0528958 |
| PGK1 | phosphoglycerate kinase 1 | 0.0521834 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0513903 |
| OPTN | optineurin | 0.0493295 |
| SETD5 | SET domain containing 5 | 0.047285 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461707 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0423246 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0420417 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0418927 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.041802 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0415639 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0412181 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.041147 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.041015 |
| ANO6 | anoctamin 6 | 0.0409664 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0407036 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0404538 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0403329 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0395448 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0391875 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0390369 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0386409 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0383371 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.03817 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0380793 |
| RAI14 | retinoic acid induced 14 | 0.0378557 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0371264 |
| HELZ | helicase with zinc finger | 0.0369823 |
| MMP12 | matrix metallopeptidase 12 | 0.036961 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0353662 |
| SNX9 | sorting nexin 9 | 0.0352223 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.035143 |
| CD44 | CD44 molecule (Indian blood group) | 0.0351307 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0349545 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0345633 |
| ZNF395 | zinc finger protein 395 | 0.0336426 |
| BRD2 | bromodomain containing 2 | 0.0333847 |
| PLIN2 | perilipin 2 | 0.0333393 |
| HLA-A | major histocompatibility complex, class I, A | 0.033188 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0328741 |
| SRP54 | signal recognition particle 54kDa | 0.0326962 |
| ZNF292 | zinc finger protein 292 | 0.0320701 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0318243 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0317907 |
| LDHA | lactate dehydrogenase A | 0.0317146 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0316111 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0313486 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0311176 |
| ARRDC3 | arrestin domain containing 3 | 0.0310824 |
| RNF24 | ring finger protein 24 | 0.0307715 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0302548 |
| SNX3 | sorting nexin 3 | 0.0301966 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0296224 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0294723 |
| MYO1B | myosin IB | 0.0293695 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0288766 |
| SPAG9 | sperm associated antigen 9 | 0.0287956 |
| WDR45B | WD repeat domain 45B | 0.0286081 |
| MATR3 | matrin 3 | 0.0285483 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.028278 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0278381 |
| USP37 | ubiquitin specific peptidase 37 | 0.0276382 |
| RNF145 | ring finger protein 145 | 0.0275084 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0272471 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0271951 |
| SEC24A | SEC24 family member A | 0.0269062 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0267731 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0267199 |
| PKM | pyruvate kinase, muscle | 0.0267117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.142739 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.133228 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.130295 |
| TMSB10 | thymosin beta 10 | -0.116358 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.11395 |
| HMGA2 | high mobility group AT-hook 2 | -0.111167 |
| GLIS3 | GLIS family zinc finger 3 | -0.0907587 |
| AHNAK | AHNAK nucleoprotein | -0.0712481 |
| RPL23 | ribosomal protein L23 | -0.0674366 |
| RPS24 | ribosomal protein S24 | -0.0665345 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0646203 |
| RIGI | RNA sensor RIG-I | -0.0638868 |
| VIM | vimentin | -0.0624157 |
| FAM20C | family with sequence similarity 20, member C | -0.0613447 |
| VCL | vinculin | -0.0601498 |
| COL1A1 | collagen, type I, alpha 1 | -0.0588314 |
| RPS27A | ribosomal protein S27a | -0.0581533 |
| NABP1 | nucleic acid binding protein 1 | -0.0555938 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0541636 |
| FN1 | fibronectin 1 | -0.0541126 |
| INTS6 | integrator complex subunit 6 | -0.0515651 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0515092 |
| RNF213 | ring finger protein 213 | -0.0483346 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0479638 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0477928 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0476208 |
| FLNA | filamin A, alpha | -0.0467702 |
| HDAC9 | histone deacetylase 9 | -0.0431268 |
| BICC1 | BicC family RNA binding protein 1 | -0.0428445 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0427616 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0424183 |
| THBS1 | thrombospondin 1 | -0.0419218 |
| TNS3 | tensin 3 | -0.041682 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0403878 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.03933 |
| DST | dystonin | -0.0383561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0376595 |
| CDH13 | cadherin 13 | -0.0365187 |
| ACTG1 | actin gamma 1 | -0.0363559 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0363179 |
| RAD51B | RAD51 paralog B | -0.0357213 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0356004 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0351247 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0349336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0347387 |
| ANXA2 | annexin A2 | -0.0345095 |
| RPS4X | ribosomal protein S4, X-linked | -0.0341687 |
| MT2A | metallothionein 2A | -0.0338714 |
| NAV1 | neuron navigator 1 | -0.0333819 |
| MX1 | MX dynamin-like GTPase 1 | -0.0322077 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.031741 |
| TPM1 | tropomyosin 1 (alpha) | -0.0316843 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0310806 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0309701 |
| UBC | ubiquitin C | -0.0306397 |
| PTK2 | protein tyrosine kinase 2 | -0.0300913 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0299256 |
| RPLP2 | ribosomal protein, large, P2 | -0.029583 |
| IER3 | immediate early response 3 | -0.0293829 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0291354 |
| ATXN1 | ataxin 1 | -0.0287407 |
| PLSCR1 | phospholipid scramblase 1 | -0.0285216 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0275011 |
| RPS21 | ribosomal protein S21 | -0.0271338 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0269772 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0266151 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0265394 |
| PTMA | prothymosin, alpha | -0.0261698 |
| SRGN | serglycin | -0.0260756 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0260615 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0258125 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0257775 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.025617 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0251784 |
| COL1A2 | collagen, type I, alpha 2 | -0.0250908 |
| RPL35A | ribosomal protein L35a | -0.0250511 |
| RRBP1 | ribosome binding protein 1 | -0.0249766 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0249553 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0245641 |
| SMAD3 | SMAD family member 3 | -0.0244034 |
| ABHD12 | abhydrolase domain containing 12 | -0.0243303 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.024157 |
| ASPH | aspartate beta-hydroxylase | -0.0238967 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0237948 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0236189 |
| SDC4 | syndecan 4 | -0.0235388 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0233914 |
| COL5A1 | collagen, type V, alpha 1 | -0.0230083 |
| TUBB | tubulin, beta class I | -0.0228727 |
| GNAS | GNAS complex locus | -0.0228359 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0228301 |
| DIAPH2 | diaphanous-related formin 2 | -0.0228112 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0226716 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0226646 |
| THBS2 | thrombospondin 2 | -0.0225971 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0225397 |
| ACTN4 | actinin, alpha 4 | -0.0222484 |
| SP100 | SP100 nuclear antigen | -0.0222094 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0220584 |
| RHEB | Ras homolog enriched in brain | -0.0220052 |
