| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.191803 |
| RPS6 | ribosomal protein S6 | 0.137909 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0695977 |
| RPS2 | ribosomal protein S2 | 0.0622166 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0584498 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0540499 |
| DSPP | dentin sialophosphoprotein | 0.0526096 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0442614 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0378667 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0366871 |
| RPS13 | ribosomal protein S13 | 0.0353467 |
| BCL2L1 | BCL2-like 1 | 0.0340445 |
| RPL35A | ribosomal protein L35a | 0.0322812 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0321186 |
| MATR3 | matrin 3 | 0.0320952 |
| RPS8 | ribosomal protein S8 | 0.0314821 |
| SEPTIN9 | septin 9 | 0.0312765 |
| SETD5 | SET domain containing 5 | 0.0308853 |
| NEBL | nebulette | 0.0307934 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0303246 |
| PNN | pinin, desmosome associated protein | 0.0288636 |
| B2M | beta-2-microglobulin | 0.0281973 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0278237 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0275315 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0264655 |
| RPS5 | ribosomal protein S5 | 0.0264485 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0256186 |
| RPL3 | ribosomal protein L3 | 0.0247742 |
| RPL13A | ribosomal protein L13a | 0.0246672 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0244743 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0233053 |
| RPL10A | ribosomal protein L10a | 0.0231058 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228766 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.02264 |
| RPS12 | ribosomal protein S12 | 0.0225879 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.022548 |
| RPS25 | ribosomal protein S25 | 0.0224265 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0223925 |
| VCL | vinculin | 0.0223504 |
| CLTC | clathrin, heavy chain (Hc) | 0.0222495 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0217353 |
| RPL36 | ribosomal protein L36 | 0.0214342 |
| RPL15 | ribosomal protein L15 | 0.0213447 |
| ATP9A | ATPase, class II, type 9A | 0.0212678 |
| MED13L | mediator complex subunit 13-like | 0.0211965 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0206418 |
| OPTN | optineurin | 0.0204867 |
| CST3 | cystatin C | 0.0200986 |
| RACK1 | receptor for activated C kinase 1 | 0.0198306 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0196675 |
| ADAR | adenosine deaminase, RNA-specific | 0.019666 |
| RPS19 | ribosomal protein S19 | 0.0190293 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0189066 |
| RPS18 | ribosomal protein S18 | 0.018842 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0186676 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0186423 |
| TMF1 | TATA element modulatory factor 1 | 0.0185669 |
| SMAD3 | SMAD family member 3 | 0.0184271 |
| MKRN1 | makorin ring finger protein 1 | 0.0183404 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0181862 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0181621 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0181063 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0180184 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0179494 |
| RPS27 | ribosomal protein S27 | 0.0178446 |
| RPL11 | ribosomal protein L11 | 0.0178114 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.017792 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0176721 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0176247 |
| MTMR3 | myotubularin related protein 3 | 0.0175321 |
| HDGF | hepatoma-derived growth factor | 0.0175219 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0173854 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.0172901 |
| RPS14 | ribosomal protein S14 | 0.0172029 |
| WWC1 | WW and C2 domain containing 1 | 0.0171471 |
| COPA | coatomer protein complex, subunit alpha | 0.0171119 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0171117 |
| RPL7A | ribosomal protein L7a | 0.0171032 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0170878 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0170367 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0169439 |
| VMP1 | vacuole membrane protein 1 | 0.016797 |
| CHMP4B | charged multivesicular body protein 4B | 0.0167884 |
| VEGFA | vascular endothelial growth factor A | 0.0167017 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0166858 |
| RPL38 | ribosomal protein L38 | 0.0166673 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0166542 |
| YY1 | YY1 transcription factor | 0.0166128 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0165438 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0165265 |
| RPLP2 | ribosomal protein, large, P2 | 0.016427 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0163452 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0162505 |
| PGK1 | phosphoglycerate kinase 1 | 0.0162189 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0161468 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0158429 |
| RPL12 | ribosomal protein L12 | 0.0157843 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0157302 |
| HMGA1 | high mobility group AT-hook 1 | 0.0157189 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0156595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.0947828 |
| AHNAK | AHNAK nucleoprotein | -0.075101 |
| EZR | ezrin | -0.0707301 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0687653 |
| TMSB10 | thymosin beta 10 | -0.060049 |
| ACTN4 | actinin, alpha 4 | -0.0592264 |
| KRT8 | keratin 8, type II | -0.0557457 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0509648 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0504962 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0490825 |
| ANXA2 | annexin A2 | -0.0486467 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0423498 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0409125 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0404797 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0394268 |
| RPS27A | ribosomal protein S27a | -0.0373567 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0357723 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0349539 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0345331 |
| CCND1 | cyclin D1 | -0.0334537 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0328873 |
| JMJD1C | jumonji domain containing 1C | -0.0327498 |
| JUN | jun proto-oncogene | -0.0322266 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0319793 |
| PERP | PERP, TP53 apoptosis effector | -0.0319238 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0317375 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0317309 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0306918 |
| EHBP1 | EH domain binding protein 1 | -0.0306061 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0299553 |
| UBE3C | ubiquitin protein ligase E3C | -0.0298648 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0297222 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0282956 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0279958 |
| RYBP | RING1 and YY1 binding protein | -0.0277609 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0274993 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.027468 |
| CDK13 | cyclin-dependent kinase 13 | -0.0266762 |
| SDC4 | syndecan 4 | -0.0265706 |
| USP24 | ubiquitin specific peptidase 24 | -0.0265649 |
| RBM25 | RNA binding motif protein 25 | -0.0262164 |
| EPCAM | epithelial cell adhesion molecule | -0.0261205 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0259013 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.025866 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0258102 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.025758 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0256874 |
| CEP95 | centrosomal protein 95kDa | -0.0256538 |
| IER3 | immediate early response 3 | -0.0249258 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0245077 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0244242 |
| FAT1 | FAT atypical cadherin 1 | -0.0242951 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0242332 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0239426 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0235091 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0234182 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0232609 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0232155 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.023176 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0231743 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0230594 |
| DNMBP | dynamin binding protein | -0.0229906 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0226107 |
| PTMA | prothymosin, alpha | -0.0225089 |
| MYO5B | myosin VB | -0.0224629 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0224227 |
| PHF3 | PHD finger protein 3 | -0.0221844 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.022014 |
| MCL1 | myeloid cell leukemia 1 | -0.0216959 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0216017 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0214622 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0213791 |
| ETNK1 | ethanolamine kinase 1 | -0.0212161 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.021095 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0209721 |
| LAMB3 | laminin, beta 3 | -0.0208107 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0207776 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.020676 |
| OGA | O-GlcNAcase | -0.0206213 |
| HDAC8 | histone deacetylase 8 | -0.0206212 |
| S100A6 | S100 calcium binding protein A6 | -0.0205671 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0204596 |
| SMYD3 | SET and MYND domain containing 3 | -0.0202547 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0201974 |
| NUP214 | nucleoporin 214kDa | -0.0201386 |
| TOP1 | topoisomerase (DNA) I | -0.0200272 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0200039 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.019934 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0198903 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0198288 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0197344 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0197209 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0197198 |
| OLA1 | Obg-like ATPase 1 | -0.0194316 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0193037 |
| LAMA4 | laminin, alpha 4 | -0.0192165 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0191899 |
| SEPTIN7 | septin 7 | -0.0189848 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0189349 |
| ATL2 | atlastin GTPase 2 | -0.0188596 |
