| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.160547 |
| RCOR1 | REST corepressor 1 | 0.111299 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0995001 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0867423 |
| NDRG1 | N-myc downstream regulated 1 | 0.0814429 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0739878 |
| RPS2 | ribosomal protein S2 | 0.0709941 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0652357 |
| GOLGA4 | golgin A4 | 0.0531165 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0518265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0517027 |
| ACTG1 | actin gamma 1 | 0.05167 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0514121 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0463044 |
| FHL2 | four and a half LIM domains 2 | 0.0449091 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0418689 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0412847 |
| MYO5B | myosin VB | 0.0390752 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0381583 |
| ATXN1 | ataxin 1 | 0.0376287 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0375762 |
| NUP58 | nucleoporin 58 | 0.0372106 |
| LAMC2 | laminin, gamma 2 | 0.0362264 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0356466 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0348066 |
| YAP1 | Yes-associated protein 1 | 0.0343266 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0342722 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0341349 |
| POTEF | POTE ankyrin domain family, member F | 0.034127 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.033355 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0326636 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0321014 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0312531 |
| SEPTIN9 | septin 9 | 0.0309336 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.029999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0292594 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0287551 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0281087 |
| ITGA6 | integrin, alpha 6 | 0.027956 |
| RNF145 | ring finger protein 145 | 0.0279266 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0272891 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0272593 |
| TMF1 | TATA element modulatory factor 1 | 0.0272368 |
| EREG | epiregulin | 0.0271359 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0264692 |
| HMGA1 | high mobility group AT-hook 1 | 0.0260021 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0259976 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0258764 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257088 |
| RPS3 | ribosomal protein S3 | 0.0256589 |
| SGMS2 | sphingomyelin synthase 2 | 0.0254749 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.025255 |
| MED13L | mediator complex subunit 13-like | 0.0251728 |
| EGR1 | early growth response 1 | 0.0251488 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0249688 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0246322 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0244655 |
| WWC1 | WW and C2 domain containing 1 | 0.0243194 |
| RPS12 | ribosomal protein S12 | 0.0238998 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0238892 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0238528 |
| RBM39 | RNA binding motif protein 39 | 0.0238193 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0237618 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0234687 |
| SLMAP | sarcolemma associated protein | 0.0234132 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0233749 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0232311 |
| DUSP4 | dual specificity phosphatase 4 | 0.0228771 |
| TMEM41B | transmembrane protein 41B | 0.0228696 |
| DCLK1 | doublecortin-like kinase 1 | 0.0227432 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0226205 |
| FLNA | filamin A, alpha | 0.0225912 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.022506 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0222137 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0221926 |
| RPS18 | ribosomal protein S18 | 0.0220183 |
| COG5 | component of oligomeric golgi complex 5 | 0.0219945 |
| RPL21 | ribosomal protein L21 | 0.0219263 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0217753 |
| SNX9 | sorting nexin 9 | 0.0216209 |
| SPAG9 | sperm associated antigen 9 | 0.0214463 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0212935 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0212391 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0210881 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0210543 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0209735 |
| YTHDC1 | YTH domain containing 1 | 0.020536 |
| MRTFA | myocardin related transcription factor A | 0.0204086 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0202005 |
| LAMA4 | laminin, alpha 4 | 0.0201245 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0199381 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0199281 |
| MT2A | metallothionein 2A | 0.0199258 |
| UPP1 | uridine phosphorylase 1 | 0.0196298 |
| UBQLN1 | ubiquilin 1 | 0.0194559 |
| FOXJ3 | forkhead box J3 | 0.0193922 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0193912 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0190419 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0190241 |
| IRS2 | insulin receptor substrate 2 | 0.0190021 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.298739 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.198579 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.121748 |
| PTMA | prothymosin, alpha | -0.111233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.100439 |
| HDAC2 | histone deacetylase 2 | -0.0995818 |
| RPL35A | ribosomal protein L35a | -0.0949837 |
| HMGA2 | high mobility group AT-hook 2 | -0.0899966 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0743902 |
| FERMT1 | fermitin family member 1 | -0.0704192 |
| RPS24 | ribosomal protein S24 | -0.0693216 |
| IER3 | immediate early response 3 | -0.063095 |
| LMO7 | LIM domain 7 | -0.0628795 |
| MKI67 | marker of proliferation Ki-67 | -0.0614407 |
| AHNAK | AHNAK nucleoprotein | -0.0612133 |
| ANXA1 | annexin A1 | -0.0595786 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0594519 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0546812 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0543477 |
| RPL34 | ribosomal protein L34 | -0.0538265 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0535031 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.053495 |
| SMYD3 | SET and MYND domain containing 3 | -0.0528007 |
| RPLP1 | ribosomal protein, large, P1 | -0.0514938 |
| RAD51B | RAD51 paralog B | -0.0505682 |
| CUX1 | cut-like homeobox 1 | -0.0497746 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497721 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0486763 |
| RPL12 | ribosomal protein L12 | -0.0470878 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464518 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0454745 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0447144 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.044532 |
| TUBB | tubulin, beta class I | -0.044486 |
| SERINC5 | serine incorporator 5 | -0.0442626 |
| RPL23 | ribosomal protein L23 | -0.0442305 |
| MTAP | methylthioadenosine phosphorylase | -0.04412 |
| FHIT | fragile histidine triad | -0.0427204 |
| PATJ | PATJ crumbs cell polarity complex component | -0.041719 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0416818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0413955 |
| AOPEP | aminopeptidase O (putative) | -0.0412662 |
| TMEM123 | transmembrane protein 123 | -0.0411336 |
| RBM25 | RNA binding motif protein 25 | -0.0406635 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0402925 |
| BMP4 | bone morphogenetic protein 4 | -0.0399092 |
| KRT8 | keratin 8, type II | -0.0394726 |
| EZR | ezrin | -0.0386181 |
| S100A6 | S100 calcium binding protein A6 | -0.0370214 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0365546 |
| CANX | calnexin | -0.0364217 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.03628 |
| TMSB10 | thymosin beta 10 | -0.0360996 |
| RPLP0 | ribosomal protein, large, P0 | -0.0358834 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0358409 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0357529 |
| ITGB4 | integrin, beta 4 | -0.0357036 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0352235 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0350049 |
| RPL4 | ribosomal protein L4 | -0.0346046 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0345995 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.034438 |
| HMGB1 | high mobility group box 1 | -0.0340277 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0338056 |
| RPS19 | ribosomal protein S19 | -0.0337501 |
| DIAPH2 | diaphanous-related formin 2 | -0.0337287 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.033712 |
| KRT18 | keratin 18, type I | -0.0321044 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0320882 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0319368 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0318756 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0318055 |
| DEK | DEK proto-oncogene | -0.0312628 |
| LAMB3 | laminin, beta 3 | -0.0307537 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0306696 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0305429 |
| EHBP1 | EH domain binding protein 1 | -0.0305426 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0303744 |
| CENPF | centromere protein F, 350/400kDa | -0.028899 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0284017 |
| FBL | fibrillarin | -0.0282873 |
| NFIA | nuclear factor I/A | -0.0282458 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0277965 |
| RPS4X | ribosomal protein S4, X-linked | -0.027637 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0276349 |
| RPL8 | ribosomal protein L8 | -0.0276189 |
| EFNA5 | ephrin-A5 | -0.0268201 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0267473 |
| HMGB2 | high mobility group box 2 | -0.0261553 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0261453 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.0257646 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0257225 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0255172 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0254213 |
| TXNRD1 | thioredoxin reductase 1 | -0.0251471 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0247963 |
| CBX3 | chromobox homolog 3 | -0.0247036 |
| S100A10 | S100 calcium binding protein A10 | -0.0245428 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0242156 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0241898 |
