| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | L1 cell adhesion molecule|The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 3897) |
| External Link | https://ncbi.nlm.nih.gov/gene/3897 |
| Similar Terms | |
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498 genes differentially expressed following the L1CAM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0153142 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0150195 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0146429 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0144234 |
| MAGEA3 | melanoma antigen family A3 | 0.013687 |
| ANXA3 | annexin A3 | 0.0130514 |
| KYNU | kynureninase | 0.0128827 |
| RNF167 | ring finger protein 167 | 0.0117271 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0114463 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0111852 |
| HSPB8 | heat shock 22kDa protein 8 | 0.011169 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0111148 |
| FHL1 | four and a half LIM domains 1 | 0.0109945 |
| FAM198B | family with sequence similarity 198, member B | 0.0108186 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.010807 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0107145 |
| MAGEA12 | melanoma antigen family A12 | 0.0106321 |
| TPM4 | tropomyosin 4 | 0.0105366 |
| FGG | fibrinogen gamma chain | 0.0103977 |
| S100A7 | S100 calcium binding protein A7 | 0.0102995 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.0102794 |
| IL6ST | interleukin 6 signal transducer | 0.0102458 |
| IFI44L | interferon-induced protein 44-like | 0.0101359 |
| GLUL | glutamate-ammonia ligase | 0.0101283 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0100263 |
| CPE | carboxypeptidase E | 0.0100256 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00999977 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00997675 |
| MCL1 | myeloid cell leukemia 1 | 0.00993136 |
| GNAS | GNAS complex locus | 0.00989341 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00984286 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00979617 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00969563 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00966573 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00963075 |
| CAV2 | caveolin 2 | 0.00962365 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0095866 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00957463 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00955994 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00952502 |
| NRN1 | neuritin 1 | 0.00949124 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00934919 |
| CTSB | cathepsin B | 0.00933077 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00932936 |
| FGF13 | fibroblast growth factor 13 | 0.00932619 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00927809 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0092646 |
| COG7 | component of oligomeric golgi complex 7 | 0.00926352 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.0092525 |
| IFI44 | interferon-induced protein 44 | 0.00923934 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00922091 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00916497 |
| ORM1 | orosomucoid 1 | 0.009144 |
| C3 | complement component 3 | 0.00911983 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.0090829 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00905355 |
| DES | desmin | 0.0089554 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.0088976 |
| CSF1R | colony stimulating factor 1 receptor | 0.00886561 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00883802 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0088329 |
| GPR171 | G protein-coupled receptor 171 | 0.00878716 |
| CFI | complement factor I | 0.00877387 |
| MLF2 | myeloid leukemia factor 2 | 0.008721 |
| WASHC4 | WASH complex subunit 4 | 0.00870606 |
| FABP7 | fatty acid binding protein 7, brain | 0.00863282 |
| CPD | carboxypeptidase D | 0.00860496 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00859859 |
| IFNGR1 | interferon gamma receptor 1 | 0.00859417 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00859219 |
| IL1R2 | interleukin 1 receptor, type II | 0.00857803 |
| YIPF5 | Yip1 domain family, member 5 | 0.0085008 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00845224 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00845223 |
| ZYX | zyxin | 0.00841927 |
| SVIL | supervillin | 0.00833861 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00832708 |
| HHEX | hematopoietically expressed homeobox | 0.00830581 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00827695 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00826708 |
| TNNC1 | troponin C type 1 (slow) | 0.00824372 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00822354 |
| MSX1 | msh homeobox 1 | 0.0082217 |
| PDZD2 | PDZ domain containing 2 | 0.00816621 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00816204 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00816055 |
| CADM1 | cell adhesion molecule 1 | 0.00812702 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00807397 |
| LY96 | lymphocyte antigen 96 | 0.00806801 |
| SST | somatostatin | 0.00805299 |
| COPA | coatomer protein complex, subunit alpha | 0.00803547 |
| CALCRL | calcitonin receptor-like | 0.00802911 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00801614 |
| IL32 | interleukin 32 | 0.00799765 |
| RNASET2 | ribonuclease T2 | 0.0079928 |
| C1S | complement component 1, s subcomponent | 0.00793954 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00793947 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00792301 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00791347 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00790111 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00789938 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00789178 |
| IL17RA | interleukin 17 receptor A | 0.0078071 |
| CD99 | CD99 molecule | 0.00780634 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00779845 |
| CTTN | cortactin | 0.0077945 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00779415 |
| SPRR3 | small proline-rich protein 3 | 0.00776526 |
| GOLGA8A | golgin A8 family, member A | 0.00776332 |
| DAZAP2 | DAZ associated protein 2 | 0.00776244 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00774478 |
| DEFB1 | defensin, beta 1 | 0.00773191 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00773107 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00770818 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00766724 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00762167 |
| FOXO1 | forkhead box O1 | 0.0076119 |
| ITGA6 | integrin, alpha 6 | 0.00760919 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00759397 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00759211 |
| B2M | beta-2-microglobulin | 0.00759037 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00757741 |
| S100P | S100 calcium binding protein P | 0.00754694 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00754449 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00752896 |
| EXOC5 | exocyst complex component 5 | 0.00751462 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | 0.00750963 |
| FGA | fibrinogen alpha chain | 0.00749218 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 0.00745024 |
| GPX3 | glutathione peroxidase 3 | 0.00743792 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00741485 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00740964 |
| CTSC | cathepsin C | 0.00740354 |
| REEP5 | receptor accessory protein 5 | 0.00739604 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0073753 |
| EFNA1 | ephrin-A1 | 0.00737173 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00736034 |
| COPS7A | COP9 signalosome subunit 7A | 0.00735189 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00734437 |
| SNX10 | sorting nexin 10 | 0.00730354 |
| SNX13 | sorting nexin 13 | 0.00730029 |
| SHTN1 | shootin 1 | 0.00729992 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00729729 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00728358 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00726239 |
| TRIM22 | tripartite motif containing 22 | 0.00725755 |
| TGM2 | transglutaminase 2 | 0.00725167 |
| MT1X | metallothionein 1X | 0.00724952 |
| MYO1C | myosin IC | 0.00722492 |
| CCK | cholecystokinin | 0.00720822 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00716851 |
| PEG3 | paternally expressed 3 | 0.0071609 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00715913 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00714492 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00712201 |
| SPRR2B | small proline-rich protein 2B | 0.00711512 |
| MT2A | metallothionein 2A | 0.00711152 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00710984 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00710441 |
| CUL1 | cullin 1 | 0.00709079 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00708674 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00708201 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00706206 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00705362 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00702389 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 0.00701307 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00699674 |
| CD53 | CD53 molecule | 0.00699306 |
| TRAM1 | translocation associated membrane protein 1 | 0.00699007 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00698596 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00695803 |
| CTSS | cathepsin S | 0.00694957 |
| PHB2 | prohibitin 2 | 0.00691678 |
| HOMER1 | homer scaffolding protein 1 | 0.00688609 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00687143 |
| RNFT1 | ring finger protein, transmembrane 1 | 0.00687047 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00686923 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00686766 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.00685599 |
| FZD6 | frizzled class receptor 6 | 0.0068424 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00684154 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00683334 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.00682265 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00681214 |
| STOM | stomatin | 0.00679285 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00679118 |
| NMD3 | NMD3 ribosome export adaptor | 0.00677657 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00676151 |
| ODC1 | ornithine decarboxylase 1 | 0.00674413 |
| AIM2 | absent in melanoma 2 | 0.00674209 |
| GSPT1 | G1 to S phase transition 1 | 0.0067378 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00673458 |
| TMEM100 | transmembrane protein 100 | 0.00673062 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00673023 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00670805 |
| MT1E | metallothionein 1E | 0.00669241 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00667854 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00665306 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00660596 |
| OSMR | oncostatin M receptor | 0.00660473 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00660003 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00658219 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00654398 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0065377 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00653474 |
| CA2 | carbonic anhydrase II | 0.00652148 |
| RHOA | ras homolog family member A | 0.00651786 |
| ASPH | aspartate beta-hydroxylase | 0.00649144 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00648945 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00648503 |
| ANXA1 | annexin A1 | 0.00647098 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00645833 |
| PRMT5 | protein arginine methyltransferase 5 | 0.00645385 |
| S100A8 | S100 calcium binding protein A8 | 0.00644949 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00644397 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00644351 |
| C4BPB | complement component 4 binding protein, beta | 0.00643281 |
| ARL1 | ADP-ribosylation factor-like 1 | 0.00643185 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00642573 |
| C7 | complement component 7 | 0.0064227 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00642006 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | 0.0064095 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.006394 |
| PRKCB | protein kinase C, beta | 0.00638506 |
| HCP5 | HLA complex P5 (non-protein coding) | 0.00637537 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00637524 |
| ATP9A | ATPase, class II, type 9A | 0.00636658 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00633085 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00630137 |
| ATG5 | autophagy related 5 | 0.00628387 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00627598 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00627289 |
| IL18 | interleukin 18 | 0.00626142 |
| ABLIM1 | actin binding LIM protein 1 | 0.00625078 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00624883 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00624809 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.0062469 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00624223 |
| SAA4 | serum amyloid A4, constitutive | 0.00623656 |
| WIF1 | WNT inhibitory factor 1 | 0.00622827 |
| MICB | MHC class I polypeptide-related sequence B | 0.00621836 |
| ERGIC2 | ERGIC and golgi 2 | 0.00621234 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00620726 |
| FGB | fibrinogen beta chain | 0.00619934 |
| MAGEA1 | melanoma antigen family A1 | 0.00619705 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00619225 |
| TSPAN8 | tetraspanin 8 | 0.00618149 |
| CORO1C | coronin, actin binding protein, 1C | 0.00614352 |
| RNF130 | ring finger protein 130 | 0.00613863 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0236506 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0202344 |
| PRPF4 | pre-mRNA processing factor 4 | -0.0189794 |
| MMP1 | matrix metallopeptidase 1 | -0.0171364 |
| WDR7 | WD repeat domain 7 | -0.0167884 |
| ADIRF | adipogenesis regulatory factor | -0.0159845 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0153536 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0140329 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0138806 |
| NID2 | nidogen 2 (osteonidogen) | -0.0137191 |
| COMP | cartilage oligomeric matrix protein | -0.0134774 |
| OLFM4 | olfactomedin 4 | -0.0130317 |
| KRT19 | keratin 19, type I | -0.0128814 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0123646 |
| MAP7 | microtubule-associated protein 7 | -0.0123348 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0122149 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0119858 |
| SMYD3 | SET and MYND domain containing 3 | -0.0119533 |
| AOC1 | amine oxidase, copper containing 1 | -0.0118362 |
| THBS1 | thrombospondin 1 | -0.0118117 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0116733 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0113726 |
| TXLNA | taxilin alpha | -0.0112039 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0111871 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0109809 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0105855 |
| HTRA1 | HtrA serine peptidase 1 | -0.0105748 |
| PF4 | platelet factor 4 | -0.0102513 |
| POSTN | periostin, osteoblast specific factor | -0.0100828 |
| PITX3 | paired-like homeodomain 3 | -0.0100778 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0100149 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.0100088 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.010004 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00999908 |
| CTSD | cathepsin D | -0.00999852 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00987314 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00978543 |
| TUBA1A | tubulin, alpha 1a | -0.00977994 |
| DPEP1 | dipeptidase 1 (renal) | -0.00959791 |
| FST | follistatin | -0.0094644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00940828 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00932485 |
| ADD3 | adducin 3 (gamma) | -0.00924649 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00923736 |
| AEBP1 | AE binding protein 1 | -0.00919745 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00918754 |
| PLAT | plasminogen activator, tissue | -0.00904035 |
| TOB1 | transducer of ERBB2, 1 | -0.00902459 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00900064 |
| PDGFD | platelet derived growth factor D | -0.0089949 |
| CTBP2 | C-terminal binding protein 2 | -0.00895778 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00887709 |
| MXRA8 | matrix-remodelling associated 8 | -0.00887369 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00884512 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0087933 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00878963 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.008734 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00871754 |
| CTSK | cathepsin K | -0.00870085 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00869581 |
| COL3A1 | collagen, type III, alpha 1 | -0.00869144 |
| COLEC12 | collectin sub-family member 12 | -0.00864924 |
| ZNF423 | zinc finger protein 423 | -0.0086446 |
| RAPSN | receptor-associated protein of the synapse | -0.00860421 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00859724 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00859471 |
| CLDN3 | claudin 3 | -0.00858523 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00856366 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00855253 |
| FADS1 | fatty acid desaturase 1 | -0.00849036 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00848247 |
| CLC | Charcot-Leyden crystal galectin | -0.00845111 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00843368 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00841596 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00840275 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00839081 |
| ANGPTL2 | angiopoietin-like 2 | -0.00836607 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00834065 |
| HBD | hemoglobin, delta | -0.00831859 |
| CA12 | carbonic anhydrase XII | -0.00828352 |
| KIF13B | kinesin family member 13B | -0.00826488 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0082456 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00822746 |
| MOK | MOK protein kinase | -0.00821457 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.00819592 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0081946 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00816497 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00807551 |
| JAG2 | jagged 2 | -0.008068 |
| LMNA | lamin A/C | -0.00804605 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00794729 |
| XYLT1 | xylosyltransferase I | -0.00794066 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00786205 |
| TSPAN4 | tetraspanin 4 | -0.00779208 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00778515 |
| MMP9 | matrix metallopeptidase 9 | -0.0077779 |
| PLIN2 | perilipin 2 | -0.00775662 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00772693 |
| FBLN2 | fibulin 2 | -0.00763792 |
| REG1B | regenerating islet-derived 1 beta | -0.00763706 |
| ESR1 | estrogen receptor 1 | -0.0076213 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00761647 |
| VEGFA | vascular endothelial growth factor A | -0.00760664 |
| EFNB2 | ephrin-B2 | -0.00758081 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00756137 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00754471 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00752645 |
| DIPK1A | divergent protein kinase domain 1A | -0.00752359 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | -0.00751834 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00749747 |
| DCLK1 | doublecortin-like kinase 1 | -0.00749052 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00746937 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00745656 |
| ZNF329 | zinc finger protein 329 | -0.00744199 |
| INHBA | inhibin, beta A | -0.00743102 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00742524 |
| GALC | galactosylceramidase | -0.00741205 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00740001 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00739167 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00737691 |
| MXRA5 | matrix-remodelling associated 5 | -0.00736735 |
| GSPT2 | G1 to S phase transition 2 | -0.00734719 |
| NOTCH1 | notch 1 | -0.00732675 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00731666 |
| TXN | thioredoxin | -0.00731509 |
| RCAN1 | regulator of calcineurin 1 | -0.00727738 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00726075 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00724434 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0072378 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.00721621 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00721156 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00719808 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.0071949 |
| BGN | biglycan | -0.00719265 |
| CD177 | CD177 molecule | -0.0071812 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00716061 |
| SNAI2 | snail family zinc finger 2 | -0.00715161 |
| CST1 | cystatin SN | -0.00711769 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00709234 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00708581 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00707672 |
| EPCAM | epithelial cell adhesion molecule | -0.00706236 |
| G0S2 | G0/G1 switch 2 | -0.00705961 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00705893 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00704527 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00703601 |
| GGCT | gamma-glutamylcyclotransferase | -0.00700491 |
| RAB25 | RAB25, member RAS oncogene family | -0.00700434 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00700148 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00699417 |
| ALAD | aminolevulinate dehydratase | -0.00698821 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00698507 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00697025 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00696956 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00696279 |
| NOTCH3 | notch 3 | -0.00695932 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00695209 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00693649 |
| AZU1 | azurocidin 1 | -0.00692143 |
| ITGB4 | integrin, beta 4 | -0.0069154 |
| COL5A2 | collagen, type V, alpha 2 | -0.00691182 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00691062 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00690266 |
| MATN2 | matrilin 2 | -0.00688715 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00688544 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00687828 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00686594 |
| HMGB3 | high mobility group box 3 | -0.00686488 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00682085 |
| CLDN4 | claudin 4 | -0.00678492 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00677903 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00676735 |
| JADE3 | jade family PHD finger 3 | -0.00675987 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00673031 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00671636 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00669588 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00668644 |
| FSTL1 | follistatin-like 1 | -0.00667406 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00665277 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00665013 |
| SLIT1 | slit homolog 1 (Drosophila) | -0.00664935 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00664602 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.00661777 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00661374 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00661351 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00661227 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00660999 |
| TEX30 | testis expressed 30 | -0.00660635 |
| EAF2 | ELL associated factor 2 | -0.00659873 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00659812 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00658586 |
| PRSS3 | protease, serine, 3 | -0.00657688 |
| WBP5 | WW domain binding protein 5 | -0.00657481 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | -0.00655536 |
| GPX4 | glutathione peroxidase 4 | -0.00654719 |
| IPO13 | importin 13 | -0.00652976 |
| CCNF | cyclin F | -0.00651899 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00651154 |
| RAI14 | retinoic acid induced 14 | -0.00651002 |
| RTN3 | reticulon 3 | -0.00648634 |
| RRAGA | Ras-related GTP binding A | -0.00647673 |
| PGRMC2 | progesterone receptor membrane component 2 | -0.00644176 |
| SDC4 | syndecan 4 | -0.00641644 |
| MICALL2 | MICAL-like 2 | -0.00641374 |
| NVL | nuclear VCP-like | -0.00640071 |
| LRRC15 | leucine rich repeat containing 15 | -0.00639733 |
| CD9 | CD9 molecule | -0.00638925 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0063869 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0063786 |
| FASN | fatty acid synthase | -0.00637763 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.00637379 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00636046 |
| EHF | ets homologous factor | -0.00634477 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.00634289 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00632897 |
| MMP19 | matrix metallopeptidase 19 | -0.0063166 |
| MLPH | melanophilin | -0.00631362 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00629633 |
| INSM1 | insulinoma-associated 1 | -0.0062888 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0062715 |
| KLF10 | Kruppel-like factor 10 | -0.00626705 |
| SDC1 | syndecan 1 | -0.00625171 |
| ANK2 | ankyrin 2, neuronal | -0.00624585 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00623254 |
| LEFTY1 | left-right determination factor 1 | -0.00621904 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00621726 |
| BRCA1 | breast cancer 1, early onset | -0.00621703 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.00620215 |
| KIAA0930 | KIAA0930 | -0.00619536 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00619253 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | -0.0061842 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00616551 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00614024 |
| STK26 | serine/threonine protein kinase 26 | -0.00613956 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00613216 |
| TMEM38B | transmembrane protein 38B | -0.00611742 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00610645 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00609842 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.00608347 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00606814 |
| FAM117A | family with sequence similarity 117, member A | -0.00603568 |
| COL10A1 | collagen, type X, alpha 1 | -0.00603418 |
| ADK | adenosine kinase | -0.00602539 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.00602186 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00601357 |
| ZNF331 | zinc finger protein 331 | -0.0059915 |
| SRPK1 | SRSF protein kinase 1 | -0.005988 |
| APOD | apolipoprotein D | -0.00598633 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00598124 |
