L33 Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human pancreatic cancer cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004571)
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Genes

305 genes with high or low expression in L33 relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
BPIFA1 BPI fold containing family A, member 1 3.40824
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.40717
DMBT1 deleted in malignant brain tumors 1 2.99831
PGBD4 piggyBac transposable element derived 4 2.82672
STC1 stanniocalcin 1 2.81195
AQP3 aquaporin 3 (Gill blood group) 2.76666
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.65496
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.65491
THSD4 thrombospondin, type I, domain containing 4 2.59878
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.52751
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.51114
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 2.25277
RHOV ras homolog family member V 2.23282
C11ORF70 chromosome 11 open reading frame 70 2.20214
ADHFE1 alcohol dehydrogenase, iron containing, 1 2.1765
PYCARD PYD and CARD domain containing 2.17272
TRIM41 tripartite motif containing 41 2.1571
CT83 cancer/testis antigen 83 2.15062
LAMB4 laminin, beta 4 2.13763
BPIFB1 BPI fold containing family B, member 1 2.13763
ASIC1 acid sensing (proton gated) ion channel 1 2.12971
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 2.1215
C1RL complement component 1, r subcomponent-like 2.11676
CXCL5 chemokine (C-X-C motif) ligand 5 2.09906
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.08019
LEMD1 LEM domain containing 1 2.07793
CLDN10 claudin 10 2.05414
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 2.0507
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.02803
TRIP11 thyroid hormone receptor interactor 11 2.0251
SMOX spermine oxidase 2.02441
PER2 period circadian clock 2 1.99228
EVA1C eva-1 homolog C (C. elegans) 1.95627
IL18R1 interleukin 18 receptor 1 1.92599
BCAM basal cell adhesion molecule (Lutheran blood group) 1.91187
MUC4 mucin 4, cell surface associated 1.90632
RAB4A RAB4A, member RAS oncogene family 1.90503
PRR34 proline rich 34 1.82847
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.82647
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 1.80538
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 1.78655
CFH complement factor H 1.78069
RIMKLB ribosomal modification protein rimK-like family member B 1.76589
SNORD104 small nucleolar RNA, C/D box 104 1.76429
YAP1 Yes-associated protein 1 1.75212
C1RL-AS1 C1RL antisense RNA 1 1.73602
FLJ26850 FLJ26850 protein 1.71861
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 1.71804
TMEM184C transmembrane protein 184C 1.70479
SP6 Sp6 transcription factor 1.70436
AQP6 aquaporin 6, kidney specific 1.70136
MIR205 microRNA 205 1.6983
SAGE1 sarcoma antigen 1 1.69658
STEAP4 STEAP family member 4 1.67609
IL20 interleukin 20 1.67222
CCDC97 coiled-coil domain containing 97 1.67106
ANO1 anoctamin 1, calcium activated chloride channel 1.67042
DGKH diacylglycerol kinase, eta 1.66882
IMPG2 interphotoreceptor matrix proteoglycan 2 1.66759
PI3 peptidase inhibitor 3, skin-derived 1.66758
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.66526
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3 1.6627
AQP5 aquaporin 5 1.63858
DPH6 diphthamine biosynthesis 6 1.63754
GNAS-AS1 GNAS antisense RNA 1 1.6348
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.63089
TRIM7 tripartite motif containing 7 1.62912
LOC100129917 uncharacterized LOC100129917 1.62151
FZD10 frizzled class receptor 10 1.62119
XPR1 xenotropic and polytropic retrovirus receptor 1 1.61732
MEOX1 mesenchyme homeobox 1 1.61289
RNFT2 ring finger protein, transmembrane 2 1.60681
SCRN2 secernin 2 1.60035
IGFL1 IGF-like family member 1 1.59675
PDE3A phosphodiesterase 3A, cGMP-inhibited 1.59318
NLRX1 NLR family member X1 1.59142
TBX18 T-box 18 1.58539
KRT6C keratin 6C, type II 1.5779
ELMO3 engulfment and cell motility 3 1.57246
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.55435
STATH statherin 1.55435
COQ3 coenzyme Q3 methyltransferase 1.55165
ZFP62 ZFP62 zinc finger protein 1.53352
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 1.52594
KRT17 keratin 17, type I 1.52294
IL1R1 interleukin 1 receptor, type I 1.52159
FAT2 FAT atypical cadherin 2 1.51747
MPPED2 metallophosphoesterase domain containing 2 1.51644
WDR5B WD repeat domain 5B 1.50712
DEFB1 defensin, beta 1 1.50669
MPZL2 myelin protein zero-like 2 1.50044
CGA glycoprotein hormones, alpha polypeptide 1.49921
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 1.49476
BIRC2 baculoviral IAP repeat containing 2 1.49452
BPIFA2 BPI fold containing family A, member 2 1.49026
NTN5 netrin 5 1.49019
TMEM39A transmembrane protein 39A 1.4873
TMEM123 transmembrane protein 123 1.48723
CSAD cysteine sulfinic acid decarboxylase 1.48617
H19 H19, imprinted maternally expressed transcript (non-protein coding) 1.48083
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 1.48026
ESRG embryonic stem cell related (non-protein coding) 1.47733
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 1.47716
CALCA calcitonin-related polypeptide alpha 1.47556
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.47383
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 1.4717
SMIM13 small integral membrane protein 13 1.47058
MOCOS molybdenum cofactor sulfurase 1.46932
CFAP57 cilia and flagella associated protein 57 1.46914
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.46571
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 1.46393
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.45701
MFAP3 microfibrillar-associated protein 3 1.45592
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2 1.45527
SLC39A2 solute carrier family 39 (zinc transporter), member 2 1.45354
TMEM14C transmembrane protein 14C 1.45065
SOX7 SRY (sex determining region Y)-box 7 1.44921
MIRLET7BHG MIRLET7B host gene 1.44679
NSD1 nuclear receptor binding SET domain protein 1 1.42698
GATSL3 GATS protein-like 3 1.42023
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 1.41481
PNKP polynucleotide kinase 3'-phosphatase 1.41315
MAVS mitochondrial antiviral signaling protein 1.40622
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 1.40495
LPAR6 lysophosphatidic acid receptor 6 1.4038
SPRR2A small proline-rich protein 2A 1.40081
PDZD2 PDZ domain containing 2 1.39877
SLPI secretory leukocyte peptidase inhibitor 1.39719
TTBK2 tau tubulin kinase 2 1.3963
PAX7 paired box 7 1.39293
MIR205HG MIR205 host gene 1.39184
SAT1 spermidine/spermine N1-acetyltransferase 1 1.38764
PLXDC2 plexin domain containing 2 1.38686
PANK3 pantothenate kinase 3 1.38312
LINC00473 long intergenic non-protein coding RNA 473 1.38181
SOSTDC1 sclerostin domain containing 1 1.38073
COMTD1 catechol-O-methyltransferase domain containing 1 1.37967
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.37653
TMPRSS11D transmembrane protease, serine 11D 1.37635
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 1.3759
SUSD2 sushi domain containing 2 1.36931
WBSCR27 Williams Beuren syndrome chromosome region 27 1.36758
FAF2 Fas associated factor family member 2 1.36372
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.35718
DOC2A double C2-like domains, alpha 1.35632
MMP13 matrix metallopeptidase 13 1.35594
ACSS3 acyl-CoA synthetase short-chain family member 3 1.35

low expression

Symbol Name Standardized Value
TPGS2 tubulin polyglutamylase complex subunit 2 -3.99892
BRAP BRCA1 associated protein -3.99875
SUMF2 sulfatase modifying factor 2 -3.4817
LOC441179 uncharacterized LOC441179 -2.67321
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.66053
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -2.5985
RND2 Rho family GTPase 2 -2.50688
TACR1 tachykinin receptor 1 -2.48828
C7ORF60 chromosome 7 open reading frame 60 -2.38477
C11ORF57 chromosome 11 open reading frame 57 -2.37978
PKN1 protein kinase N1 -2.37715
LOC283731 uncharacterized LOC283731 -2.35876
DCAF13 DDB1 and CUL4 associated factor 13 -2.31631
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -2.282
PPP2R5B protein phosphatase 2, regulatory subunit B', beta -2.27945
LPIN2 lipin 2 -2.27168
TBC1D23 TBC1 domain family, member 23 -2.26467
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -2.26271
SMIM21 small integral membrane protein 21 -2.25703
LOC100505784 uncharacterized LOC100505784 -2.23766
C7ORF73 chromosome 7 open reading frame 73 -2.23204
SIRPD signal-regulatory protein delta -2.22514
EBF3 early B-cell factor 3 -2.21965
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.21544
SIRAL1 SIR2 antiphage like 1 -2.20067
SRPK2 SRSF protein kinase 2 -2.17898
CDK5 cyclin-dependent kinase 5 -2.1558
FRG2C FSHD region gene 2 family, member C -2.13006
TEX26 testis expressed 26 -2.12758
TRIM24 tripartite motif containing 24 -2.12694
ADAM32 ADAM metallopeptidase domain 32 -2.12664
CRHBP corticotropin releasing hormone binding protein -2.10724
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.08431
C3ORF38 chromosome 3 open reading frame 38 -2.0738
HILPDA hypoxia inducible lipid droplet-associated -2.05538
TRPC5 transient receptor potential cation channel, subfamily C, member 5 -2.04743
NCF4 neutrophil cytosolic factor 4, 40kDa -2.03355
BEST3 bestrophin 3 -2.03108
CUL1 cullin 1 -2.02221
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.97937
MTCH2 mitochondrial carrier 2 -1.96876
DRD3 dopamine receptor D3 -1.96423
ZNF398 zinc finger protein 398 -1.9455
RYBP RING1 and YY1 binding protein -1.93192
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -1.92903
ZNF746 zinc finger protein 746 -1.9173
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.91029
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 -1.91008
CYSRT1 cysteine-rich tail protein 1 -1.90868
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -1.90259
TNPO3 transportin 3 -1.90144
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit -1.89528
STK11 serine/threonine kinase 11 -1.89036
NMRAL1 NmrA-like family domain containing 1 -1.88634
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.88001
ZIC4 Zic family member 4 -1.87468
C1QTNF7 C1q and tumor necrosis factor related protein 7 -1.87051
OSTM1-AS1 OSTM1 antisense RNA 1 -1.86661
UBE2N ubiquitin-conjugating enzyme E2N -1.8536
RNF4 ring finger protein 4 -1.8494
BAALC brain and acute leukemia, cytoplasmic -1.83429
LRRC37A5P leucine rich repeat containing 37, member A5, pseudogene -1.83315
ALG9 ALG9, alpha-1,2-mannosyltransferase -1.81919
GCC1 GRIP and coiled-coil domain containing 1 -1.81466
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -1.80667
LOC100505474 -1.78939
TAS2R40 taste receptor, type 2, member 40 -1.78922
ART1 ADP-ribosyltransferase 1 -1.78548
PRDM4 PR domain containing 4 -1.77206
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 -1.76408
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic -1.76043
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta -1.75924
RGAG4 retrotransposon gag domain containing 4 -1.75051
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -1.74317
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase -1.72965
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -1.72363
EVC2 Ellis van Creveld syndrome 2 -1.72116
ZNF654 zinc finger protein 654 -1.71792
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -1.70766
LOC100130219 uncharacterized LOC100130219 -1.69693
ZMAT1 zinc finger, matrin-type 1 -1.69363
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.68294
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -1.68258
COG5 component of oligomeric golgi complex 5 -1.68041
IER3IP1 immediate early response 3 interacting protein 1 -1.67842
NLRP3 NLR family, pyrin domain containing 3 -1.67696
OR10A5 olfactory receptor, family 10, subfamily A, member 5 -1.67554
ZW10 zw10 kinetochore protein -1.6735
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -1.66814
CRYBB2 crystallin, beta B2 -1.66528
LOC93432 -1.66131
BPGM 2,3-bisphosphoglycerate mutase -1.6607
IQUB IQ motif and ubiquitin domain containing -1.65965
ALB albumin -1.65208
MMD monocyte to macrophage differentiation-associated -1.64946
KIAA1328 KIAA1328 -1.6469
ARHGAP10 Rho GTPase activating protein 10 -1.63969
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -1.63576
IFRD1 interferon-related developmental regulator 1 -1.63042
TPMT thiopurine S-methyltransferase -1.62467
FNDC9 fibronectin type III domain containing 9 -1.62072
LINC00588 long intergenic non-protein coding RNA 588 -1.61972
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -1.61792
RHEB Ras homolog enriched in brain -1.61501
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -1.61361
CCDC54 coiled-coil domain containing 54 -1.61344
TRHDE thyrotropin-releasing hormone degrading enzyme -1.61145
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -1.60555
ADO 2-aminoethanethiol (cysteamine) dioxygenase -1.59376
CES1P1 carboxylesterase 1 pseudogene 1 -1.58774
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.58624
RINT1 RAD50 interactor 1 -1.58393
LOC100506371 uncharacterized LOC100506371 -1.58372
ATP10A ATPase, class V, type 10A -1.58366
ERICH3 glutamate-rich 3 -1.58277
SCCPDH saccharopine dehydrogenase (putative) -1.57827
WIPI2 WD repeat domain, phosphoinositide interacting 2 -1.57489
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.5744
SPATA25 spermatogenesis associated 25 -1.56794
SLMO1 slowmo homolog 1 (Drosophila) -1.56705
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -1.56457
LOC286059 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain pseudogene -1.55979
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A -1.5581
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding) -1.55161
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -1.54785
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -1.54618
CDYL chromodomain protein, Y-like -1.54591
LRRN4CL LRRN4 C-terminal like -1.54525
ARF5 ADP-ribosylation factor 5 -1.54338
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -1.53985
LOC100507516 uncharacterized LOC100507516 -1.53856
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.53447
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.51918
ESAM endothelial cell adhesion molecule -1.51626
C7ORF49 chromosome 7 open reading frame 49 -1.51253
SRF serum response factor (c-fos serum response element-binding transcription factor) -1.50758
ZBTB46 zinc finger and BTB domain containing 46 -1.50593
TWIST2 twist family bHLH transcription factor 2 -1.50248
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 -1.49503
TMUB1 transmembrane and ubiquitin-like domain containing 1 -1.4938
FCRL3 Fc receptor-like 3 -1.49147
STRIP1 striatin interacting protein 1 -1.49043
NAT8 N-acetyltransferase 8 (GCN5-related, putative) -1.48919
SYT5 synaptotagmin V -1.48651
SIK3 SIK family kinase 3 -1.47776
HABP4 hyaluronan binding protein 4 -1.47688
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 -1.47622
DVL2 dishevelled segment polarity protein 2 -1.4751
PGRMC2 progesterone receptor membrane component 2 -1.4741
KLHDC10 kelch domain containing 10 -1.47139
MAGEE2 melanoma antigen family E2 -1.4699
FXYD4 FXYD domain containing ion transport regulator 4 -1.46753
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -1.46753
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 -1.46413
ADCY8 adenylate cyclase 8 (brain) -1.46275
ZNF471 zinc finger protein 471 -1.45828
MKRN1 makorin ring finger protein 1 -1.45785
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) -1.45201