L428 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
External Link https://depmap.org/portal/cell_line/ACH-000754
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Genes

740 gene knockdowns changing fitness of L428 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 18.912
MGST1 microsomal glutathione S-transferase 1 18.4752
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 12.4606
TAT tyrosine aminotransferase 10.8726
REL v-rel avian reticuloendotheliosis viral oncogene homolog 10.7172
ODF2 outer dense fiber of sperm tails 2 10.5784
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 10.5156
IL13RA1 interleukin 13 receptor, alpha 1 10.3255
TMEM222 transmembrane protein 222 9.78984
EBAG9 estrogen receptor binding site associated, antigen, 9 9.50454
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 8.91819
DMRT2 doublesex and mab-3 related transcription factor 2 8.84253
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 8.50085
HECA headcase homolog (Drosophila) 8.49864
RB1 retinoblastoma 1 8.34146
ADCY5 adenylate cyclase 5 8.23725
TLR1 toll-like receptor 1 8.18314
CCNDBP1 cyclin D-type binding-protein 1 8.0288
SLCO5A1 solute carrier organic anion transporter family, member 5A1 7.92542
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 7.8075
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 7.77383
IL4R interleukin 4 receptor 7.69688
APOF apolipoprotein F 7.61739
TNS1 tensin 1 7.61209
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 7.57476
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 7.53676
ZC4H2 zinc finger, C4H2 domain containing 7.11998
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 7.05821
AICDA activation-induced cytidine deaminase 6.99324
STX7 syntaxin 7 6.98017
FAM161B family with sequence similarity 161, member B 6.94268
TCTN3 tectonic family member 3 6.88613
CLIC6 chloride intracellular channel 6 6.85198
PRKG2 protein kinase, cGMP-dependent, type II 6.74387
FOXD4L5 forkhead box D4-like 5 6.68138
PTPRB protein tyrosine phosphatase, receptor type, B 6.67538
FHOD1 formin homology 2 domain containing 1 6.64671
RNASE8 ribonuclease, RNase A family, 8 6.62418
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 6.59986
CHADL chondroadherin-like 6.56788
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 6.4747
MICA MHC class I polypeptide-related sequence A 6.42443
BATF3 basic leucine zipper transcription factor, ATF-like 3 6.34805
CLDN3 claudin 3 6.3463
SIRT6 sirtuin 6 6.32126
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 6.27712
DND1 DND microRNA-mediated repression inhibitor 1 6.2521
ARL15 ADP-ribosylation factor-like 15 6.23856
SYNDIG1 synapse differentiation inducing 1 6.21973
FEM1A fem-1 homolog a (C. elegans) 6.19428
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 6.16267
ARC activity-regulated cytoskeleton-associated protein 6.08738
VWA7 von Willebrand factor A domain containing 7 6.02451
NECTIN1 nectin cell adhesion molecule 1 6.0205
PKP1 plakophilin 1 5.97208
CBLN3 cerebellin 3 precursor 5.82381
KCTD9 potassium channel tetramerization domain containing 9 5.79777
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 5.79051
HAS1 hyaluronan synthase 1 5.77142
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 5.74827
DMBX1 diencephalon/mesencephalon homeobox 1 5.74486
ASB13 ankyrin repeat and SOCS box containing 13 5.71309
ANGPTL2 angiopoietin-like 2 5.6891
NHSL1 NHS-like 1 5.68248
TSPAN15 tetraspanin 15 5.65483
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 5.65472
PARP10 poly (ADP-ribose) polymerase family, member 10 5.61184
LOXL4 lysyl oxidase-like 4 5.59782
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 5.57627
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 5.57311
C9ORF50 chromosome 9 open reading frame 50 5.55477
C1QTNF3 C1q and tumor necrosis factor related protein 3 5.53185
ATXN1 ataxin 1 5.5303
DAGLA diacylglycerol lipase, alpha 5.48685
FAM71F1 family with sequence similarity 71, member F1 5.46324
PLP1 proteolipid protein 1 5.45776
OR10G3 olfactory receptor, family 10, subfamily G, member 3 5.45661
CST2 cystatin SA 5.40485
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 5.38895
SNX29 sorting nexin 29 5.38607
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 5.34224
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 5.3406
WWC1 WW and C2 domain containing 1 5.27853
CTRL chymotrypsin-like 5.27836
ARHGAP25 Rho GTPase activating protein 25 5.2681
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 5.24624
SCYL2 SCY1-like 2 (S. cerevisiae) 5.22825
ANKRD18A ankyrin repeat domain 18A 5.21865
ZDHHC12 zinc finger, DHHC-type containing 12 5.2084
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 5.17106
GNG13 guanine nucleotide binding protein (G protein), gamma 13 5.15407
CTSL cathepsin L 5.14649
OR4D10 olfactory receptor, family 4, subfamily D, member 10 5.14436
SLC35G6 solute carrier family 35, member G6 5.12892
CIDEA cell death-inducing DFFA-like effector a 5.12138
ATXN1L ataxin 1-like 5.06358
INHA inhibin, alpha 5.047
TMEM37 transmembrane protein 37 5.02776
CAMP cathelicidin antimicrobial peptide 5.02736
RABGAP1L RAB GTPase activating protein 1-like 5.01865
MEIS3 Meis homeobox 3 5.01831
TMEM59 transmembrane protein 59 4.98938
PURB purine-rich element binding protein B 4.96585
TUBB3 tubulin, beta 3 class III 4.94164
SH3PXD2B SH3 and PX domains 2B 4.9398
OR6C68 olfactory receptor, family 6, subfamily C, member 68 4.9175
COLGALT2 collagen beta(1-O)galactosyltransferase 2 4.90761
HSDL1 hydroxysteroid dehydrogenase like 1 4.90062
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4.88331
ABRACL ABRA C-terminal like 4.88263
FAM163A family with sequence similarity 163, member A 4.79278
SH3GLB2 SH3-domain GRB2-like endophilin B2 4.77363
BBC3 BCL2 binding component 3 4.7662
RAG2 recombination activating gene 2 4.75194
FAM109B family with sequence similarity 109, member B 4.75075
LCE3D late cornified envelope 3D 4.69906
LBHD1 LBH domain containing 1 4.68323
OR2Y1 olfactory receptor, family 2, subfamily Y, member 1 4.68177
C19ORF18 chromosome 19 open reading frame 18 4.66443
FAM193B family with sequence similarity 193, member B 4.61437
SYBU syntabulin (syntaxin-interacting) 4.59623
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 4.58392
SPEM1 spermatid maturation 1 4.5831
APOLD1 apolipoprotein L domain containing 1 4.57817
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 4.53322
GPR108 G protein-coupled receptor 108 4.52468
SUSD6 sushi domain containing 6 4.50358
OVOL2 ovo-like zinc finger 2 4.45051
HEG1 heart development protein with EGF-like domains 1 4.44598
LAPTM4B lysosomal protein transmembrane 4 beta 4.44014
C3ORF67 chromosome 3 open reading frame 67 4.43554
NT5C3B 5'-nucleotidase, cytosolic IIIB 4.42832
LDB3 LIM domain binding 3 4.4164
OSTM1 osteopetrosis associated transmembrane protein 1 4.39235
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 4.38977
SLAMF8 SLAM family member 8 4.37539
EPHA10 EPH receptor A10 4.36458
PCDHB5 protocadherin beta 5 4.36178
SSTR1 somatostatin receptor 1 4.33894
ARHGAP39 Rho GTPase activating protein 39 4.33846
PRRT3 proline-rich transmembrane protein 3 4.33413
OTOS otospiralin 4.30614
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 4.29776
EPHA8 EPH receptor A8 4.27901
OR51S1 olfactory receptor, family 51, subfamily S, member 1 4.27338
MSR1 macrophage scavenger receptor 1 4.24577
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 4.23927
GBP6 guanylate binding protein family, member 6 4.20789
PPAP2A phosphatidic acid phosphatase type 2A 4.2052
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 4.20251
SLC39A5 solute carrier family 39 (zinc transporter), member 5 4.20091
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 4.17318
CLEC18A C-type lectin domain family 18, member A 4.16735
MYO18A myosin XVIIIA 4.13585
INTU inturned planar cell polarity protein 4.13518
THEMIS thymocyte selection associated 4.12247
UTRN utrophin 4.12103
SNAI3 snail family zinc finger 3 4.11215
MR1 major histocompatibility complex, class I-related 4.10441
NIBAN2 niban apoptosis regulator 2 4.09071
SFTPD surfactant protein D 4.06906
DCST2 DC-STAMP domain containing 2 4.0652
ADIRF adipogenesis regulatory factor 4.0558
REG3G regenerating islet-derived 3 gamma 4.03634
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 4.0248
GOPC golgi-associated PDZ and coiled-coil motif containing 4.01209
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 4.00007
DENND11 DENN domain containing 11 3.97537
GCLM glutamate-cysteine ligase, modifier subunit 3.97398
ADI1 acireductone dioxygenase 1 3.96766
ZGPAT zinc finger, CCCH-type with G patch domain 3.96639
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 3.96404
FBXO34 F-box protein 34 3.95906
DUSP23 dual specificity phosphatase 23 3.95684
LRRC24 leucine rich repeat containing 24 3.945
KRTAP10-2 keratin associated protein 10-2 3.94288
FBH1 F-box DNA helicase 1 3.93445
PCDHA1 protocadherin alpha 1 3.92658
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 3.92334
MAP7D2 MAP7 domain containing 2 3.92014
SUMO3 small ubiquitin-like modifier 3 3.91879
LRRN4CL LRRN4 C-terminal like 3.91181
RAB2B RAB2B, member RAS oncogene family 3.90102
TNF tumor necrosis factor 3.89942
SPP1 secreted phosphoprotein 1 3.89475
FLYWCH2 FLYWCH family member 2 3.87414
C16ORF93 chromosome 16 open reading frame 93 3.86954
MAP3K12 mitogen-activated protein kinase kinase kinase 12 3.8688
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 3.86536
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 3.86022
SECISBP2 SECIS binding protein 2 3.84004
OR6P1 olfactory receptor, family 6, subfamily P, member 1 3.83875
TACR2 tachykinin receptor 2 3.83709
ITPKA inositol-trisphosphate 3-kinase A 3.82862
SMOX spermine oxidase 3.82136
ATAD3C ATPase family, AAA domain containing 3C 3.8136
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 3.79266
BMP15 bone morphogenetic protein 15 3.78258
SYCE1 synaptonemal complex central element protein 1 3.77783
UNC119 unc-119 homolog (C. elegans) 3.77362
CATSPER2 cation channel, sperm associated 2 3.77143
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 3.76119
ACOT2 acyl-CoA thioesterase 2 3.75919
MISP mitotic spindle positioning 3.75828
IRF4 interferon regulatory factor 4 3.75394
DNAI1 dynein, axonemal, intermediate chain 1 3.74998
LAMA4 laminin, alpha 4 3.73809
STAG3 stromal antigen 3 3.72632
RAX2 retina and anterior neural fold homeobox 2 3.72582
MIXL1 Mix paired-like homeobox 3.70608
TCHP trichoplein, keratin filament binding 3.70376
FBXL7 F-box and leucine-rich repeat protein 7 3.68565
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 3.68379
NCMAP noncompact myelin associated protein 3.68352
AMIGO3 adhesion molecule with Ig-like domain 3 3.66664
GIP gastric inhibitory polypeptide 3.66303
PTH1R parathyroid hormone 1 receptor 3.66059
KRTDAP keratinocyte differentiation-associated protein 3.66039
TF transferrin 3.65484
NPAS3 neuronal PAS domain protein 3 3.65315
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 3.65014
CHUK conserved helix-loop-helix ubiquitous kinase 3.6453
MAGEB16 melanoma antigen family B16 3.63421
ALS2CL ALS2 C-terminal like 3.62726
COL17A1 collagen, type XVII, alpha 1 3.61995
BOLL boule-like RNA-binding protein 3.61537
GSTM2 glutathione S-transferase mu 2 (muscle) 3.61359
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 3.60788
POTEM POTE ankyrin domain family, member M 3.6029
SHF Src homology 2 domain containing F 3.58711
TMEM88B transmembrane protein 88B 3.58185
RASAL2 RAS protein activator like 2 3.57755
TRIM33 tripartite motif containing 33 3.55497
PHLDB1 pleckstrin homology-like domain, family B, member 1 3.54968
SIGLEC9 sialic acid binding Ig-like lectin 9 3.54063
BTBD2 BTB (POZ) domain containing 2 3.53555
GAMT guanidinoacetate N-methyltransferase 3.53449
LCE3C late cornified envelope 3C 3.51532
CXCR1 chemokine (C-X-C motif) receptor 1 3.51089
C14ORF180 chromosome 14 open reading frame 180 3.50968
TMEM54 transmembrane protein 54 3.49086
TTLL11 tubulin tyrosine ligase-like family member 11 3.48537
SYTL1 synaptotagmin-like 1 3.47517
SP3 Sp3 transcription factor 3.4655
OR13C4 olfactory receptor, family 13, subfamily C, member 4 3.44965
COLEC12 collectin sub-family member 12 3.44616
STEAP1 six transmembrane epithelial antigen of the prostate 1 3.44027
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 3.44016
GHITM growth hormone inducible transmembrane protein 3.43339
NDRG2 NDRG family member 2 3.43259
OR51A4 olfactory receptor, family 51, subfamily A, member 4 3.42506
TGIF2 TGFB-induced factor homeobox 2 3.41431
MAPK10 mitogen-activated protein kinase 10 3.40047
EPB41L2 erythrocyte membrane protein band 4.1-like 2 3.39648
SMR3A submaxillary gland androgen regulated protein 3A 3.3819
ZFYVE1 zinc finger, FYVE domain containing 1 3.38104
PCDHB12 protocadherin beta 12 3.37995
HPS4 Hermansky-Pudlak syndrome 4 3.37912
PIP prolactin-induced protein 3.36547
MC5R melanocortin 5 receptor 3.36479
SYT8 synaptotagmin VIII 3.35127
TMEM8B transmembrane protein 8B 3.34457
TSSK4 testis-specific serine kinase 4 3.33893
KLK9 kallikrein-related peptidase 9 3.3384
IRF9 interferon regulatory factor 9 3.33119
LDLRAP1 low density lipoprotein receptor adaptor protein 1 3.31436
EVC2 Ellis van Creveld syndrome 2 3.30785
ZNF282 zinc finger protein 282 3.30743
IL21 interleukin 21 3.30548
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 3.29905
LY6G5B lymphocyte antigen 6 complex, locus G5B 3.29681
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 3.29375
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 3.29356
RDH8 retinol dehydrogenase 8 (all-trans) 3.28924
ARMC9 armadillo repeat containing 9 3.28285
LHB luteinizing hormone beta polypeptide 3.27902
EXOC3L1 exocyst complex component 3-like 1 3.2786
RHOT1 ras homolog family member T1 3.25419
DLL3 delta-like 3 (Drosophila) 3.25142
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 3.25031
SHROOM2 shroom family member 2 3.24792
RAB34 RAB34, member RAS oncogene family 3.23984
STAC SH3 and cysteine rich domain 3.23556
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.21153
ACKR3 atypical chemokine receptor 3 3.20018
GADL1 glutamate decarboxylase-like 1 3.19393
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.1908
MPPED1 metallophosphoesterase domain containing 1 3.1846
OR10G2 olfactory receptor, family 10, subfamily G, member 2 3.18415
PRKD3 protein kinase D3 3.17311
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 3.17023
CHD6 chromodomain helicase DNA binding protein 6 3.16147
STOM stomatin 3.15205
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.15175
CCSAP centriole, cilia and spindle-associated protein 3.14843
WDFY3 WD repeat and FYVE domain containing 3 3.1479
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 3.14258
CNTNAP1 contactin associated protein 1 3.14224
MAGT1 magnesium transporter 1 3.13776
CCND2 cyclin D2 3.12622
MAGEA11 melanoma antigen family A11 3.12398
PPP1R18 protein phosphatase 1, regulatory subunit 18 3.12369
DCLK2 doublecortin-like kinase 2 3.12122
C16ORF86 chromosome 16 open reading frame 86 3.11998
CDV3 CDV3 homolog (mouse) 3.11871
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 3.11536
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 3.09995
DNER delta/notch-like EGF repeat containing 3.099
YBX2 Y box binding protein 2 3.09863
TUFT1 tuftelin 1 3.09115
GPR6 G protein-coupled receptor 6 3.08874
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 3.08529
LGALS16 lectin, galactoside-binding, soluble, 16 3.0848
C6ORF10 chromosome 6 open reading frame 10 3.08465
SET SET nuclear proto-oncogene 3.08138
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 3.07729
CCNO cyclin O 3.07432
C6ORF222 chromosome 6 open reading frame 222 3.07199
FAM184A family with sequence similarity 184, member A 3.06666
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 3.0624
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 3.05884
KMT5C lysine methyltransferase 5C 3.05645
RIPK3 receptor-interacting serine-threonine kinase 3 3.05529
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 3.04556
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 3.04227
MBD1 methyl-CpG binding domain protein 1 3.03512
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 3.03334
TMEM130 transmembrane protein 130 3.03256
ASTE1 asteroid homolog 1 (Drosophila) 3.03154
MCRIP2 MAPK regulated corepressor interacting protein 2 3.02478
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 3.01858
IFITM2 interferon induced transmembrane protein 2 3.01624
C17ORF98 chromosome 17 open reading frame 98 3.01455
CD160 CD160 molecule 3.01378
CAPNS2 calpain, small subunit 2 3.01126
GSS glutathione synthetase 2.99911
ZNF32 zinc finger protein 32 2.99712
AOC3 amine oxidase, copper containing 3 2.99684
NMU neuromedin U 2.99566
AK1 adenylate kinase 1 2.99102
PDZK1 PDZ domain containing 1 2.99033
SLC25A48 solute carrier family 25, member 48 2.98872
TMEM180 transmembrane protein 180 2.98437
ANXA5 annexin A5 2.98364
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 2.98003
JAK1 Janus kinase 1 2.97212
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 2.97205
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.97122
NME8 NME/NM23 family member 8 2.96769
CYSRT1 cysteine-rich tail protein 1 2.96596
KLK14 kallikrein-related peptidase 14 2.9612
PFKP phosphofructokinase, platelet 2.95993
OSM oncostatin M 2.95978
FAM194C family with sequence similarity 149 member C 2.95533
PRR22 proline rich 22 2.95418
MUC7 mucin 7, secreted 2.95255
SCRT1 scratch family zinc finger 1 2.95103
VSX2 visual system homeobox 2 2.9446
ITGA10 integrin, alpha 10 2.93873
RBP2 retinol binding protein 2, cellular 2.93843
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.93637
DPRX divergent-paired related homeobox 2.93511
COMT catechol-O-methyltransferase 2.93478
IFI27L2 interferon, alpha-inducible protein 27-like 2 2.93472
FUCA2 fucosidase, alpha-L- 2, plasma 2.93317
TPPP2 tubulin polymerization-promoting protein family member 2 2.92642
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.92508
NKX2-5 NK2 homeobox 5 2.92426
GPR26 G protein-coupled receptor 26 2.92075
LDHAL6B lactate dehydrogenase A-like 6B 2.91708
IGSF8 immunoglobulin superfamily, member 8 2.91111
FAM47E family with sequence similarity 47, member E 2.90856
AARSD1 alanyl-tRNA synthetase domain containing 1 2.8979
NOTCH4 notch 4 2.89513
STK31 serine/threonine kinase 31 2.89126
THAP4 THAP domain containing 4 2.88996
GFRA3 GDNF family receptor alpha 3 2.8875
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.8857
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.88293
AKR1C4 aldo-keto reductase family 1, member C4 2.88029
HDAC5 histone deacetylase 5 2.8798
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.87946
RCVRN recoverin 2.87727
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.8742
SPANXN2 SPANX family, member N2 2.87078
FLOT2 flotillin 2 2.86895
AJUBA ajuba LIM protein 2.86261
CRYM crystallin, mu 2.86242
IL17C interleukin 17C 2.84882
ZIK1 zinc finger protein interacting with K protein 1 2.84876
MTM1 myotubularin 1 2.8473
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.84269
HIST1H2BI histone cluster 1, H2bi 2.83409
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.83106
PSPN persephin 2.83072
AMH anti-Mullerian hormone 2.82665
R3HDM4 R3H domain containing 4 2.8251
AQP12B aquaporin 12B 2.81273
OR52B6 olfactory receptor, family 52, subfamily B, member 6 2.80671
TWIST2 twist family bHLH transcription factor 2 2.80439
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 2.80412
ARMS2 age-related maculopathy susceptibility 2 2.79687
SLC22A17 solute carrier family 22, member 17 2.79617
IGFBP6 insulin-like growth factor binding protein 6 2.79547
CDC20B cell division cycle 20B 2.79362
H2BC1 H2B clustered histone 1 2.78843
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 2.7877
KRT7 keratin 7, type II 2.78682
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.78455
CNOT12 CCR4-NOT transcription complex subunit 12 2.78324
METTL13 methyltransferase like 13 2.78155
STC2 stanniocalcin 2 2.77799
CPA5 carboxypeptidase A5 2.77481
NOS1 nitric oxide synthase 1 (neuronal) 2.77027
MARCKSL1 MARCKS-like 1 2.77004
TTC36 tetratricopeptide repeat domain 36 2.76982
LAMC3 laminin, gamma 3 2.76639
C19ORF12 chromosome 19 open reading frame 12 2.76337
BST1 bone marrow stromal cell antigen 1 2.75983
ARL10 ADP-ribosylation factor-like 10 2.75631
BSDC1 BSD domain containing 1 2.74749
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 2.74587
CCR9 chemokine (C-C motif) receptor 9 2.74206
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.73478
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.73403
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.73314
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 2.72771
BAG6 BCL2-associated athanogene 6 2.71956
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 2.70941
RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing 2.70816
CCDC88B coiled-coil domain containing 88B 2.70792
DNM1 dynamin 1 2.69857
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.69764
TAPBPL TAP binding protein-like 2.69751
YDJC YdjC homolog (bacterial) 2.69298
GIPC2 GIPC PDZ domain containing family, member 2 2.68458
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 2.68382
EIF4E2 eukaryotic translation initiation factor 4E family member 2 2.67528
OR10A4 olfactory receptor, family 10, subfamily A, member 4 2.67434
CORO1A coronin, actin binding protein, 1A 2.65968
FCRL6 Fc receptor-like 6 2.65667
LCN10 lipocalin 10 2.64855
PIAS3 protein inhibitor of activated STAT, 3 2.6456
CCKAR cholecystokinin A receptor 2.64385
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.6378
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.63633
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.62423
ANG angiogenin, ribonuclease, RNase A family, 5 2.62353
OR52K2 olfactory receptor, family 52, subfamily K, member 2 2.62266
AGO4 argonaute RISC catalytic component 4 2.62242
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.61907
CYB5D2 cytochrome b5 domain containing 2 2.61836
DYSF dysferlin 2.61823
TICAM2 toll-like receptor adaptor molecule 2 2.61429
CCL7 chemokine (C-C motif) ligand 7 2.60347
GRPR gastrin-releasing peptide receptor 2.60237
APOOL apolipoprotein O-like 2.60208
IL15 interleukin 15 2.60052
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.60008
FAM179A family with sequence similarity 179, member A 2.59563
C1ORF210 chromosome 1 open reading frame 210 2.59328
FUT2 fucosyltransferase 2 (secretor status included) 2.59095
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.58858
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.58772
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 2.58684
FAM91A1 family with sequence similarity 91, member A1 2.58557
LRRC3 leucine rich repeat containing 3 2.57985
SCRN2 secernin 2 2.57806
CCER2 coiled-coil glutamate-rich protein 2 2.57746
FAM9C family with sequence similarity 9, member C 2.57423
FREM2 FRAS1 related extracellular matrix protein 2 2.57284
SCAI suppressor of cancer cell invasion 2.57205
PDCD1LG2 programmed cell death 1 ligand 2 2.56337
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.55984
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.55805
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 2.55707
KRT18 keratin 18, type I 2.55663
ZC3H12A zinc finger CCCH-type containing 12A 2.55565
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.55494
FANCD2OS FANCD2 opposite strand 2.55219
ZNF205 zinc finger protein 205 2.55138
GPR21 G protein-coupled receptor 21 2.54673
SFR1 SWI5-dependent recombination repair 1 2.54634
DES desmin 2.54594
CXCL9 chemokine (C-X-C motif) ligand 9 2.54586
TEP1 telomerase-associated protein 1 2.54355
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.54177
FHL3 four and a half LIM domains 3 2.53913
PAGE4 P antigen family, member 4 (prostate associated) 2.53664
DDAH2 dimethylarginine dimethylaminohydrolase 2 2.53512
ZNF212 zinc finger protein 212 2.53407
PDCD1 programmed cell death 1 2.52869
ZFP57 ZFP57 zinc finger protein 2.52794
OXER1 oxoeicosanoid (OXE) receptor 1 2.52779
SRI sorcin 2.5274
FAM167A family with sequence similarity 167, member A 2.52037
LMAN2 lectin, mannose-binding 2 2.51828
OR1L3 olfactory receptor, family 1, subfamily L, member 3 2.51621
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.51478
EPDR1 ependymin related 1 2.512
TMEM253 transmembrane protein 253 2.51104
NEU4 sialidase 4 2.51082
CHIA chitinase, acidic 2.5076
PSD2 pleckstrin and Sec7 domain containing 2 2.50754
NECTIN3 nectin cell adhesion molecule 3 2.50642
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2.50392
METTL22 methyltransferase like 22 2.50205
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 2.50062
PREPL prolyl endopeptidase-like 2.49827
ERRFI1 ERBB receptor feedback inhibitor 1 2.4952
PATL2 protein associated with topoisomerase II homolog 2 (yeast) 2.49463
MIDN midnolin 2.49105
IL17D interleukin 17D 2.48812
RNF223 ring finger protein 223 2.48673
OLFML3 olfactomedin-like 3 2.48585
CEP89 centrosomal protein 89kDa 2.48396
HEXIM2 hexamethylene bis-acetamide inducible 2 2.4785
FAT2 FAT atypical cadherin 2 2.47821
BMP8B bone morphogenetic protein 8b 2.47781
KLHL29 kelch-like family member 29 2.47568
C5ORF63 chromosome 5 open reading frame 63 2.47499
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2.47413
BAHD1 bromo adjacent homology domain containing 1 2.47294
LCE4A late cornified envelope 4A 2.47219
MXRA7 matrix-remodelling associated 7 2.47087
TSSK1B testis-specific serine kinase 1B 2.46998
SNTG2 syntrophin, gamma 2 2.46921
SLC44A4 solute carrier family 44, member 4 2.46885
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.46824
TLE2 transducin-like enhancer of split 2 2.46614
CLNK cytokine-dependent hematopoietic cell linker 2.46593
CBFB core-binding factor, beta subunit 2.46423
MYO16 myosin XVI 2.46349
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.45954
SMAD2 SMAD family member 2 2.45673
IDUA iduronidase, alpha-L- 2.45335
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.44704
LYZL4 lysozyme-like 4 2.44229
PCDHGA3 protocadherin gamma subfamily A, 3 2.44199
RBMXL2 RNA binding motif protein, X-linked-like 2 2.43941
VTN vitronectin 2.43922
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.43584
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 2.43336
GPX5 glutathione peroxidase 5 2.43281
MTPN myotrophin 2.42967
CLUH clustered mitochondria (cluA/CLU1) homolog 2.42849
AMT aminomethyltransferase 2.42822
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 2.42816
SHKBP1 SH3KBP1 binding protein 1 2.42661
FGF17 fibroblast growth factor 17 2.42291
WDR86 WD repeat domain 86 2.41942
ZNF549 zinc finger protein 549 2.41718
YIPF1 Yip1 domain family, member 1 2.41237
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 2.41179
TMEM176A transmembrane protein 176A 2.41112
FAM207A family with sequence similarity 207, member A 2.41006
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.40983
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.40957
CD300E CD300e molecule 2.40906
PROP1 PROP paired-like homeobox 1 2.40521
SLFN13 schlafen family member 13 2.40434
GATA3 GATA binding protein 3 2.40348
ADGRA1 adhesion G protein-coupled receptor A1 2.40313
SDF2 stromal cell-derived factor 2 2.40208
ZC3HAV1 zinc finger CCCH-type, antiviral 1 2.40027
PLA2G2E phospholipase A2, group IIE 2.39979
ADCY4 adenylate cyclase 4 2.39815
CLIP3 CAP-GLY domain containing linker protein 3 2.39495
RIPPLY2 ripply transcriptional repressor 2 2.39417
IFI27 interferon, alpha-inducible protein 27 2.39296
FADD Fas (TNFRSF6)-associated via death domain 2.38212
PCDHB16 protocadherin beta 16 2.37786
CNGA2 cyclic nucleotide gated channel alpha 2 2.36563
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 2.3643
ARF6 ADP-ribosylation factor 6 2.36316
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.35407
SFXN2 sideroflexin 2 2.35284
MREG melanoregulin 2.35193
CD4 CD4 molecule 2.35158
TCAP titin-cap 2.34938
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 2.34892
IL23R interleukin 23 receptor 2.34509
FAM180A family with sequence similarity 180, member A 2.34123
ZNF286A zinc finger protein 286A 2.33809
SMC1B structural maintenance of chromosomes 1B 2.33064
NKD2 naked cuticle homolog 2 (Drosophila) 2.32893
FAIM2 Fas apoptotic inhibitory molecule 2 2.32839
CABP1 calcium binding protein 1 2.32496
TXNL1 thioredoxin-like 1 2.32338
TP53I3 tumor protein p53 inducible protein 3 2.32249
UNC5C unc-5 homolog C (C. elegans) 2.31944
KRT78 keratin 78, type II 2.31879
SAMD5 sterile alpha motif domain containing 5 2.31403
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 2.3104
STK4 serine/threonine kinase 4 2.3089
RND1 Rho family GTPase 1 2.30825
GIMAP1 GTPase, IMAP family member 1 2.30715
ZNF503 zinc finger protein 503 2.30664
IFITM1 interferon induced transmembrane protein 1 2.30376
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.30322
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.2949
BRAP BRCA1 associated protein 2.29189
FAM110A family with sequence similarity 110, member A 2.2909
FAM151A family with sequence similarity 151, member A 2.2866
LCE1B late cornified envelope 1B 2.28388
TMEM140 transmembrane protein 140 2.2777
CNN2 calponin 2 2.27757
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.27724
MRGPRE MAS-related GPR, member E 2.2757
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.27014
CNTNAP4 contactin associated protein-like 4 2.26825
TRIP6 thyroid hormone receptor interactor 6 2.26408
HHEX hematopoietically expressed homeobox 2.25882
ADAM11 ADAM metallopeptidase domain 11 2.25861
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.25746
PTCRA pre T-cell antigen receptor alpha 2.2484
KIF1A kinesin family member 1A 2.24574
MAL mal, T-cell differentiation protein 2.24364
ZFHX2 zinc finger homeobox 2 2.23918
FXYD3 FXYD domain containing ion transport regulator 3 2.23514
GPATCH8 G patch domain containing 8 2.23415
ZNF367 zinc finger protein 367 2.2329
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 2.23281
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.2322
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 2.23038
SUOX sulfite oxidase 2.22938
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.22938
CRYGC crystallin, gamma C 2.22305
AMPD2 adenosine monophosphate deaminase 2 2.22248
ARID4A AT rich interactive domain 4A (RBP1-like) 2.22208
SUMO1 small ubiquitin-like modifier 1 2.2216
DYNLRB2 dynein, light chain, roadblock-type 2 2.21909
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.21895
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 2.21784
SP100 SP100 nuclear antigen 2.21769
VAT1 vesicle amine transport 1 2.21387
GJA9 gap junction protein, alpha 9, 59kDa 2.21232
IVL involucrin 2.20914
GPR153 G protein-coupled receptor 153 2.2019
FAM71F2 family with sequence similarity 71, member F2 2.20004
GJB1 gap junction protein, beta 1, 32kDa 2.19931
FABP7 fatty acid binding protein 7, brain 2.1964
C9ORF16 chromosome 9 open reading frame 16 2.19439
ZBED8L ZBED8 like 2.18666
ARL5C ADP-ribosylation factor-like 5C 2.18238
GALP galanin-like peptide 2.18209
BAALC brain and acute leukemia, cytoplasmic 2.18205
ARHGAP35 Rho GTPase activating protein 35 2.18169
DEPTOR DEP domain containing MTOR-interacting protein 2.1804
EMC8 ER membrane protein complex subunit 8 2.18008
ALX3 ALX homeobox 3 2.17949
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2.1772
PAQR7 progestin and adipoQ receptor family member VII 2.17655
AOX1 aldehyde oxidase 1 2.17481
ARHGAP10 Rho GTPase activating protein 10 2.1719
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.16727
FGD1 FYVE, RhoGEF and PH domain containing 1 2.16471
RPH3AL rabphilin 3A-like (without C2 domains) 2.16173
RNF166 ring finger protein 166 2.15794
EFR3B EFR3 homolog B (S. cerevisiae) 2.15504
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.15438
HIGD1A HIG1 hypoxia inducible domain family, member 1A 2.14907
TEX9 testis expressed 9 2.14215
ZBTB5 zinc finger and BTB domain containing 5 2.13963
FAM89A family with sequence similarity 89, member A 2.13639
PDYN prodynorphin 2.13491
XPO4 exportin 4 2.1343
CERCAM cerebral endothelial cell adhesion molecule 2.12959
ART5 ADP-ribosyltransferase 5 2.12744
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.12108
LGALS2 lectin, galactoside-binding, soluble, 2 2.11662
UCN2 urocortin 2 2.11599
C8G complement component 8, gamma polypeptide 2.10713
WDR93 WD repeat domain 93 2.10526
NCALD neurocalcin delta 2.10477
TREX1 three prime repair exonuclease 1 2.10476
ERICH5 glutamate-rich 5 2.1038
RNF215 ring finger protein 215 2.10325
COMP cartilage oligomeric matrix protein 2.10193
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 2.10163
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.10084
ZDHHC7 zinc finger, DHHC-type containing 7 2.09661
LEMD1 LEM domain containing 1 2.09611
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.09028
RFPL3 ret finger protein-like 3 2.08548
AQP7 aquaporin 7 2.08357
ACOT8 acyl-CoA thioesterase 8 2.08016
SDHAF2 succinate dehydrogenase complex assembly factor 2 2.07573
THUMPD3 THUMP domain containing 3 2.07393
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.0723
ANKRD37 ankyrin repeat domain 37 2.07115
RILPL1 Rab interacting lysosomal protein-like 1 2.06846
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.06547
GUCA2A guanylate cyclase activator 2A (guanylin) 2.06538
C20ORF202 chromosome 20 open reading frame 202 2.06517
DMAC2L distal membrane arm assembly component 2 like 2.06222
CPQ carboxypeptidase Q 2.06137
POU4F2 POU class 4 homeobox 2 2.05991
SIRPB1 signal-regulatory protein beta 1 2.05392
GNAS GNAS complex locus 2.05315
PPP6C protein phosphatase 6, catalytic subunit 2.05264
ORAI3 ORAI calcium release-activated calcium modulator 3 2.04892
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.04839
CFAP45 cilia and flagella associated protein 45 2.04791
ZNF468 zinc finger protein 468 2.04747
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.0471
ZNF273 zinc finger protein 273 2.04628
CDH16 cadherin 16, KSP-cadherin 2.04539
EVX2 even-skipped homeobox 2 2.04535
GXYLT2 glucoside xylosyltransferase 2 2.04525
MYH1 myosin, heavy chain 1, skeletal muscle, adult 2.04416
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.04362
ZNF646 zinc finger protein 646 2.04346
RUFY1 RUN and FYVE domain containing 1 2.04346
GATA5 GATA binding protein 5 2.04287
CRELD1 cysteine-rich with EGF-like domains 1 2.04275
FAT4 FAT atypical cadherin 4 2.03967
OR52K1 olfactory receptor, family 52, subfamily K, member 1 2.0378
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.03704
ACBD3 acyl-CoA binding domain containing 3 2.03624
C6ORF25 chromosome 6 open reading frame 25 2.0357
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 2.03332
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.0311
TMC4 transmembrane channel-like 4 2.02178
BCAR3 breast cancer anti-estrogen resistance 3 2.01953
PRMT7 protein arginine methyltransferase 7 2.01918
RNASE13 ribonuclease, RNase A family, 13 (non-active) 2.01832
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2.01821
SEC24C SEC24 family member C 2.01599
LZTS2 leucine zipper, putative tumor suppressor 2 2.01292
CLTB clathrin, light chain B 2.01219
TMPRSS11E transmembrane protease, serine 11E 2.01071
OLFM4 olfactomedin 4 2.01055
OR6S1 olfactory receptor, family 6, subfamily S, member 1 2.01037
LTB4R leukotriene B4 receptor 2.00664
KLHDC9 kelch domain containing 9 2.0046
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2.00401
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.00143
USP12 ubiquitin specific peptidase 12 2.00077
WDR38 WD repeat domain 38 2.00063