| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3|This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 8649) |
| External Link | https://ncbi.nlm.nih.gov/gene/8649 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the LAMTOR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0139468 |
| S100A9 | S100 calcium binding protein A9 | 0.0115402 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.0109997 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0108667 |
| S100A7 | S100 calcium binding protein A7 | 0.0107578 |
| C7 | complement component 7 | 0.0104338 |
| AEBP1 | AE binding protein 1 | 0.0101179 |
| LCN2 | lipocalin 2 | 0.00987498 |
| WT1 | Wilms tumor 1 | 0.00976786 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0096383 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00942998 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00935287 |
| LYZ | lysozyme | 0.00926539 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00911778 |
| CSTA | cystatin A (stefin A) | 0.00905129 |
| VCAN | versican | 0.00888361 |
| NELL2 | NEL-like 2 (chicken) | 0.00883793 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0087793 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0086315 |
| SRGN | serglycin | 0.00845169 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00845116 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00833015 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00825577 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00817842 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00814954 |
| ANXA6 | annexin A6 | 0.00814001 |
| RRM2 | ribonucleotide reductase M2 | 0.00813357 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00800057 |
| S100A12 | S100 calcium binding protein A12 | 0.00787658 |
| CD44 | CD44 molecule (Indian blood group) | 0.00778481 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00773788 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.0076587 |
| KLK8 | kallikrein-related peptidase 8 | 0.00762335 |
| RPIA | ribose 5-phosphate isomerase A | 0.00762301 |
| CYTIP | cytohesin 1 interacting protein | 0.0075327 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00751216 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00745941 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00744679 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00741173 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00740994 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00738129 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00734025 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00728363 |
| COG7 | component of oligomeric golgi complex 7 | 0.00725442 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00722266 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00718832 |
| NDRG1 | N-myc downstream regulated 1 | 0.0071627 |
| ELANE | elastase, neutrophil expressed | 0.007145 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00714194 |
| RNF144A | ring finger protein 144A | 0.00710043 |
| HBD | hemoglobin, delta | 0.00709191 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00704897 |
| XPO7 | exportin 7 | 0.00700639 |
| OLFM4 | olfactomedin 4 | 0.00695863 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00688994 |
| XK | X-linked Kx blood group | 0.00686285 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00681606 |
| TRIB2 | tribbles pseudokinase 2 | 0.00679494 |
| PCNA | proliferating cell nuclear antigen | 0.00678748 |
| NVL | nuclear VCP-like | 0.00677398 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00675734 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 0.00674818 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00674779 |
| S100A8 | S100 calcium binding protein A8 | 0.00674077 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00672851 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00672046 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00670571 |
| NTS | neurotensin | 0.00668483 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00664651 |
| ZW10 | zw10 kinetochore protein | 0.00662941 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00662709 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00661239 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00660446 |
| NPTX2 | neuronal pentraxin II | 0.00660049 |
| CLGN | calmegin | 0.00657682 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00653938 |
| VNN1 | vanin 1 | 0.0065305 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00651624 |
| PITX3 | paired-like homeodomain 3 | 0.00646603 |
| PCGF2 | polycomb group ring finger 2 | 0.00644382 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.0064364 |
| LTF | lactotransferrin | 0.00641463 |
| PNMA8A | PNMA family member 8A | 0.00639741 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00637376 |
| LOXL1 | lysyl oxidase-like 1 | 0.00635031 |
| CA12 | carbonic anhydrase XII | 0.00633743 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00627903 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00627815 |
| ASS1 | argininosuccinate synthase 1 | 0.00627432 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00626431 |
| ADD3 | adducin 3 (gamma) | 0.00626284 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00623637 |
| MAL | mal, T-cell differentiation protein | 0.00622801 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00621873 |
| DEFB1 | defensin, beta 1 | 0.00620165 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00618879 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00618515 |
| RTN3 | reticulon 3 | 0.00617864 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00617684 |
| DAXX | death-domain associated protein | 0.0061741 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00617174 |
| ARG1 | arginase 1 | 0.00616004 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00615659 |
| ACP3 | acid phosphatase 3 | 0.00613713 |
| MLEC | malectin | 0.00612241 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00611024 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | 0.00610743 |
| METTL7A | methyltransferase like 7A | 0.00608814 |
| ITM2C | integral membrane protein 2C | 0.00606565 |
| PTK2 | protein tyrosine kinase 2 | 0.00605536 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.0060463 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00604502 |
| GUCY2C | guanylate cyclase 2C | 0.00602947 |
| SLC38A10 | solute carrier family 38, member 10 | 0.00602844 |
| TMSB15A | thymosin beta 15a | 0.00601103 |
| HMBS | hydroxymethylbilane synthase | 0.00598346 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00597864 |
| UROD | uroporphyrinogen decarboxylase | 0.0059779 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00594856 |
| CIRBP | cold inducible RNA binding protein | 0.00591116 |
| GMPR | guanosine monophosphate reductase | 0.00590823 |
| TFF1 | trefoil factor 1 | 0.00588239 |
| CCDC85B | coiled-coil domain containing 85B | 0.00584507 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00584133 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00582538 |
| PRKCA | protein kinase C, alpha | 0.00582324 |
| H1-2 | H1.2 linker histone, cluster member | 0.00581278 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00580977 |
| TADA2A | transcriptional adaptor 2A | 0.00579366 |
| ASRGL1 | asparaginase like 1 | 0.00579296 |
| RAI14 | retinoic acid induced 14 | 0.00577297 |
| HMGB2 | high mobility group box 2 | 0.00572908 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00571555 |
| SLAMF7 | SLAM family member 7 | 0.00570981 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00570878 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00570774 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00567994 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00565518 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00565369 |
| TOX3 | TOX high mobility group box family member 3 | 0.00563659 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00563361 |
| CDK14 | cyclin-dependent kinase 14 | 0.00562619 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.00562191 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00561819 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00560477 |
| XBP1 | X-box binding protein 1 | 0.00560382 |
| ABHD10 | abhydrolase domain containing 10 | 0.00560275 |
| GAS1 | growth arrest-specific 1 | 0.00559903 |
| THBS2 | thrombospondin 2 | 0.0055965 |
| AQP9 | aquaporin 9 | 0.0055931 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00558444 |
| RBM38 | RNA binding motif protein 38 | 0.00558039 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00557466 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00557204 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00556504 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00555671 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00555475 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00554542 |
| CHGB | chromogranin B | 0.00554227 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00552637 |
| RAB13 | RAB13, member RAS oncogene family | 0.00552038 |
| GAS6 | growth arrest-specific 6 | 0.00551372 |
| HOXC6 | homeobox C6 | 0.0055051 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00550413 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00550007 |
| AOC1 | amine oxidase, copper containing 1 | 0.00549431 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.0054854 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00546953 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00546229 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00545819 |
| EVI2A | ecotropic viral integration site 2A | 0.0054239 |
| LY75 | lymphocyte antigen 75 | 0.00542128 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0054204 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00541093 |
| SDC1 | syndecan 1 | 0.0053933 |
| FAM46C | family with sequence similarity 46, member C | 0.00538724 |
| AMH | anti-Mullerian hormone | 0.00538073 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.00537863 |
| PLCL1 | phospholipase C-like 1 | 0.00537336 |
| LTA4H | leukotriene A4 hydrolase | 0.00534335 |
| CLC | Charcot-Leyden crystal galectin | 0.00533883 |
| PROM1 | prominin 1 | 0.00533451 |
| BLVRB | biliverdin reductase B | 0.00532677 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00530936 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00530243 |
| IPP | intracisternal A particle-promoted polypeptide | 0.00528828 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.00528592 |
| TOR3A | torsin family 3, member A | 0.00528527 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00526204 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00524372 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00523962 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00523265 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00522836 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00520135 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00519675 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00519238 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.00518787 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 0.00518596 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00518317 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00515996 |
| AATF | apoptosis antagonizing transcription factor | 0.00515839 |
| VNN2 | vanin 2 | 0.00515345 |
| PLIN3 | perilipin 3 | 0.00515044 |
| ALAD | aminolevulinate dehydratase | 0.00514909 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00514529 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00514162 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00513664 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00513657 |
| FADS1 | fatty acid desaturase 1 | 0.00512187 |
| CES1 | carboxylesterase 1 | 0.00510898 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00510486 |
| NEFH | neurofilament, heavy polypeptide | 0.00509357 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00509273 |
| PFKM | phosphofructokinase, muscle | 0.00505537 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.0050523 |
| INSR | insulin receptor | 0.00504746 |
| IQCE | IQ motif containing E | 0.00504558 |
| IFT74 | intraflagellar transport 74 | 0.00504502 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00504275 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00503138 |
| DHFR | dihydrofolate reductase | 0.00502357 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00502267 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | 0.00502258 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00501529 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00501216 |
| JUND | jun D proto-oncogene | 0.00501071 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.0049892 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.00497986 |
| MRPS10 | mitochondrial ribosomal protein S10 | 0.00497784 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00496017 |
| ERP29 | endoplasmic reticulum protein 29 | 0.00495019 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00494208 |
| CFD | complement factor D (adipsin) | 0.00493653 |
| EMILIN1 | elastin microfibril interfacer 1 | 0.00492604 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.0049202 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00490529 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00489864 |
| FBL | fibrillarin | 0.00489169 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.00489114 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00485858 |
| CDC42 | cell division cycle 42 | 0.00485385 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00484662 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00484423 |
| NID2 | nidogen 2 (osteonidogen) | 0.00484307 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 0.00483705 |
| PGLS | 6-phosphogluconolactonase | 0.00483646 |
| SUSD4 | sushi domain containing 4 | 0.00482536 |
| DIAPH2 | diaphanous-related formin 2 | 0.00481632 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00481485 |
| RIOX2 | ribosomal oxygenase 2 | 0.00479201 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -0.0156665 |
| MYBPC1 | myosin binding protein C, slow type | -0.0146743 |
| CADM1 | cell adhesion molecule 1 | -0.0135243 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.013299 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.013264 |
| EMP1 | epithelial membrane protein 1 | -0.0130397 |
| TNNC1 | troponin C type 1 (slow) | -0.0119413 |
| TTN | titin | -0.0116515 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0110197 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00998139 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00962396 |
| MSX1 | msh homeobox 1 | -0.00961747 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0095769 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00944684 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00931115 |
| GSN | gelsolin | -0.0092051 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00886789 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00880941 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00875921 |
| CKM | creatine kinase, muscle | -0.00869681 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00854794 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00852764 |
| SIRT3 | sirtuin 3 | -0.00852375 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00849821 |
| TPD52L1 | tumor protein D52-like 1 | -0.00839126 |
| XIC | X chromosome inactivation center | -0.00838173 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00836856 |
| PEG10 | paternally expressed 10 | -0.00829655 |
| MOB4 | MOB family member 4, phocein | -0.00819302 |
| DLX5 | distal-less homeobox 5 | -0.00815248 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0081387 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00807857 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00807779 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00800654 |
| S100A10 | S100 calcium binding protein A10 | -0.00795888 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00794335 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00793054 |
| FGF13 | fibroblast growth factor 13 | -0.00792641 |
| FHL1 | four and a half LIM domains 1 | -0.00783403 |
| COMT | catechol-O-methyltransferase | -0.00780986 |
| HOMER1 | homer scaffolding protein 1 | -0.00777279 |
| PGC | progastricsin (pepsinogen C) | -0.0077558 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00767981 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00767756 |
| RC3H2 | ring finger and CCCH-type domains 2 | -0.00756153 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00754396 |
| MEX3C | mex-3 RNA binding family member C | -0.00746562 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00744314 |
| KLHL41 | kelch-like family member 41 | -0.00740294 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00730387 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00728104 |
| TNNC2 | troponin C type 2 (fast) | -0.0072783 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00724971 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00722282 |
| CRYAB | crystallin, alpha B | -0.00722006 |
| MYOT | myotilin | -0.00716612 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00716269 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00709077 |
| OLFML2A | olfactomedin-like 2A | -0.00708851 |
| STC2 | stanniocalcin 2 | -0.00704742 |
| KRT5 | keratin 5, type II | -0.00704167 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00703828 |
| MEF2C | myocyte enhancer factor 2C | -0.00701519 |
| CD163 | CD163 molecule | -0.00700714 |
| TOR1A | torsin family 1, member A (torsin A) | -0.0069638 |
| DMD | dystrophin | -0.00694248 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00693939 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0069325 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00693174 |
| MB | myoglobin | -0.00691117 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00688031 |
| ECM1 | extracellular matrix protein 1 | -0.00685253 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00681872 |
| TAC1 | tachykinin, precursor 1 | -0.00680238 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00679823 |
| TSPAN13 | tetraspanin 13 | -0.00679593 |
| NRN1 | neuritin 1 | -0.00678529 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00676474 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00676329 |
| KRT17 | keratin 17, type I | -0.00673847 |
| KIF5B | kinesin family member 5B | -0.0066661 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00666553 |
| KRT13 | keratin 13, type I | -0.00666255 |
| CCNA2 | cyclin A2 | -0.00665393 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00662928 |
| USP6NL | USP6 N-terminal like | -0.00662283 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00661497 |
| SFTPB | surfactant protein B | -0.00652695 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.0065013 |
| PERP | PERP, TP53 apoptosis effector | -0.00649623 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00648015 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00647983 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00647592 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00642789 |
| CHMP4A | charged multivesicular body protein 4A | -0.00640593 |
| KRT6A | keratin 6A, type II | -0.00639301 |
| VGLL4 | vestigial-like family member 4 | -0.00637421 |
| FMOD | fibromodulin | -0.00637295 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.0063681 |
| MAP7 | microtubule-associated protein 7 | -0.00635711 |
| WIF1 | WNT inhibitory factor 1 | -0.00634073 |
| CD9 | CD9 molecule | -0.00632886 |
| CNTN1 | contactin 1 | -0.00631865 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00628144 |
| PRSS23 | protease, serine, 23 | -0.00627642 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00625105 |
| TMEM70 | transmembrane protein 70 | -0.00623296 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00622925 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00622611 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00621874 |
| MIR22HG | MIR22 host gene | -0.00620911 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.00620107 |
| CCNG2 | cyclin G2 | -0.0061849 |
| BMP2 | bone morphogenetic protein 2 | -0.00618436 |
| DCLK1 | doublecortin-like kinase 1 | -0.00618356 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00616738 |
| ACTN2 | actinin, alpha 2 | -0.00615133 |
| SPRR3 | small proline-rich protein 3 | -0.0061513 |
| LMBRD1 | LMBR1 domain containing 1 | -0.00614615 |
| ABHD3 | abhydrolase domain containing 3 | -0.00614491 |
| CST3 | cystatin C | -0.00614209 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00611148 |
| ENO3 | enolase 3 (beta, muscle) | -0.00611039 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00609915 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00608333 |
| FABP7 | fatty acid binding protein 7, brain | -0.0060824 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00608115 |
| MYO6 | myosin VI | -0.00606719 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0060587 |
| FOXG1 | forkhead box G1 | -0.00603725 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00601699 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00600168 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.0060015 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00597717 |
| LAMC2 | laminin, gamma 2 | -0.00595146 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00594408 |
| TMEM47 | transmembrane protein 47 | -0.00593902 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0059347 |
| ACTB | actin, beta | -0.00592005 |
| TPM3 | tropomyosin 3 | -0.00591943 |
| HMOX1 | heme oxygenase 1 | -0.00589311 |
| SLN | sarcolipin | -0.00589278 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00588333 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0058832 |
| SMAD7 | SMAD family member 7 | -0.00585643 |
| KLF9 | Kruppel-like factor 9 | -0.00585408 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00585208 |
| ZNF281 | zinc finger protein 281 | -0.00584458 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00583789 |
| E2F5 | E2F transcription factor 5, p130-binding | -0.00583543 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00581068 |
| TOX | thymocyte selection-associated high mobility group box | -0.00580793 |
| LAMB3 | laminin, beta 3 | -0.0058077 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00580208 |
| IL33R | interleukin 33 receptor | -0.00578867 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.00578059 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00575306 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00575225 |
| SIK1 | salt-inducible kinase 1 | -0.0057315 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00567604 |
| SNX7 | sorting nexin 7 | -0.00567425 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00567264 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00564537 |
| AUTS2 | autism susceptibility candidate 2 | -0.00564325 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00563159 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.0056308 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.0056305 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00561494 |
| LRRC1 | leucine rich repeat containing 1 | -0.00561384 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00560285 |
| FGG | fibrinogen gamma chain | -0.00558937 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00557909 |
| NPTN | neuroplastin | -0.00556567 |
| DSP | desmoplakin | -0.00556545 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00555863 |
| CTSV | cathepsin V | -0.0055534 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00554462 |
| TAGLN2 | transgelin 2 | -0.00554385 |
| BAG3 | BCL2-associated athanogene 3 | -0.0055389 |
| USP25 | ubiquitin specific peptidase 25 | -0.00552888 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00552866 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | -0.00552201 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00551803 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00551405 |
| POSTN | periostin, osteoblast specific factor | -0.00550941 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00550036 |
| STAB1 | stabilin 1 | -0.00547412 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00547338 |
| RAB5IF | RAB5 interacting factor | -0.00546987 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0054496 |
| DSTN | destrin (actin depolymerizing factor) | -0.00544167 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00543941 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0054392 |
| SFTPA2 | surfactant protein A2 | -0.00543707 |
| YAP1 | Yes-associated protein 1 | -0.00543253 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00542399 |
| A2M | alpha-2-macroglobulin | -0.00542353 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00540773 |
| S100A2 | S100 calcium binding protein A2 | -0.00537898 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00536819 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00536217 |
| MTF2 | metal response element binding transcription factor 2 | -0.00536001 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00535723 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00535287 |
| QKI | QKI, KH domain containing, RNA binding | -0.00535167 |
| NKX2-1 | NK2 homeobox 1 | -0.00534262 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00534006 |
| MRPS28 | mitochondrial ribosomal protein S28 | -0.00533873 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00533083 |
| NCK1 | NCK adaptor protein 1 | -0.00532761 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00531873 |
| WEE1 | WEE1 G2 checkpoint kinase | -0.00530925 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.0053092 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00530434 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00530413 |
| MMP7 | matrix metallopeptidase 7 | -0.00530187 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00529091 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00528951 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00528673 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00528374 |
| TSPAN7 | tetraspanin 7 | -0.00527931 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0052761 |
| FZD10 | frizzled class receptor 10 | -0.00526184 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0052535 |
| CTSZ | cathepsin Z | -0.00524096 |
| CASD1 | CAS1 domain containing 1 | -0.00523957 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00523889 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00523673 |
| MYOZ2 | myozenin 2 | -0.00523499 |
| PON2 | paraoxonase 2 | -0.00523386 |
| SMPX | small muscle protein, X-linked | -0.00521973 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0052107 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0052087 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00520798 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00520431 |
| PLS3 | plastin 3 | -0.00517777 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00516849 |
| TMEM43 | transmembrane protein 43 | -0.00516126 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00515587 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.0051391 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00513478 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00513309 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00513208 |
| CCNC | cyclin C | -0.00512747 |
| CAPN6 | calpain 6 | -0.00512086 |
| COL2A1 | collagen, type II, alpha 1 | -0.00511491 |
| EGR2 | early growth response 2 | -0.00508175 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00508043 |
| C11ORF58 | chromosome 11 open reading frame 58 | -0.00506818 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00505609 |
