| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.140925 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.127141 |
| HMGA2 | high mobility group AT-hook 2 | 0.108369 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.103801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0787452 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0705292 |
| YAP1 | Yes-associated protein 1 | 0.0665164 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0547818 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0535303 |
| DST | dystonin | 0.0532212 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0515513 |
| NHSL1 | NHS-like 1 | 0.0512013 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0504104 |
| INTS6 | integrator complex subunit 6 | 0.0469998 |
| ANXA1 | annexin A1 | 0.0442217 |
| PCDH7 | protocadherin 7 | 0.0420335 |
| EGR1 | early growth response 1 | 0.0414052 |
| ACTG1 | actin gamma 1 | 0.04089 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0394793 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0390264 |
| EHBP1 | EH domain binding protein 1 | 0.0367238 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0352944 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.033992 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0336816 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0333629 |
| LDHA | lactate dehydrogenase A | 0.0330198 |
| ADIPOR2 | adiponectin receptor 2 | 0.0327061 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0313155 |
| CUX1 | cut-like homeobox 1 | 0.030849 |
| MKI67 | marker of proliferation Ki-67 | 0.0300838 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0299034 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0298386 |
| MMP12 | matrix metallopeptidase 12 | 0.0293834 |
| NEBL | nebulette | 0.0282049 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0273854 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0270214 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0269911 |
| EDARADD | EDAR-associated death domain | 0.0260502 |
| MAP1B | microtubule-associated protein 1B | 0.025476 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0245654 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245401 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0239855 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0237081 |
| RASAL2 | RAS protein activator like 2 | 0.0236931 |
| MTAP | methylthioadenosine phosphorylase | 0.0233756 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0232855 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0230771 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.02269 |
| SETX | senataxin | 0.022677 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0226285 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0222136 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0221903 |
| PDGFC | platelet derived growth factor C | 0.022146 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0219747 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0218511 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0217657 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.021141 |
| EXOC4 | exocyst complex component 4 | 0.0209603 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0209369 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0205316 |
| CEP112 | centrosomal protein 112kDa | 0.020238 |
| ASPH | aspartate beta-hydroxylase | 0.0202058 |
| CMIP | c-Maf inducing protein | 0.0196373 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0193345 |
| JMJD1C | jumonji domain containing 1C | 0.0192923 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0191625 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.018859 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0188497 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0188141 |
| PRDX1 | peroxiredoxin 1 | 0.0184513 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0183784 |
| PCDH9 | protocadherin 9 | 0.0183124 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0182793 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0182474 |
| NUP98 | nucleoporin 98kDa | 0.0180597 |
| LRRC23 | leucine rich repeat containing 23 | 0.0180505 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0179904 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0178649 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0177083 |
| CREM | cAMP responsive element modulator | 0.0176041 |
| MYPN | myopalladin | 0.017592 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0174947 |
| RSU1 | Ras suppressor protein 1 | 0.0172325 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0171801 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0170398 |
| PDCD6 | programmed cell death 6 | 0.0167321 |
| DTNA | dystrobrevin, alpha | 0.016537 |
| RRM2 | ribonucleotide reductase M2 | 0.0164531 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.016403 |
| HDAC9 | histone deacetylase 9 | 0.0163605 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0162657 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0161801 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0161659 |
| TBCA | tubulin folding cofactor A | 0.0159865 |
| TPM4 | tropomyosin 4 | 0.0159356 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0159109 |
| NAV3 | neuron navigator 3 | 0.0158321 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0156157 |
| R3HDM2 | R3H domain containing 2 | 0.0154803 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0154482 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.105117 |
| AREG | amphiregulin | -0.0721426 |
| VIM | vimentin | -0.0715604 |
| PCBP2 | poly(rC) binding protein 2 | -0.0623399 |
| UBC | ubiquitin C | -0.061803 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0617664 |
| RPS27A | ribosomal protein S27a | -0.060946 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0494726 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0441537 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0433424 |
| RPL23 | ribosomal protein L23 | -0.0414124 |
| AHNAK | AHNAK nucleoprotein | -0.0397936 |
| XPO1 | exportin 1 | -0.0374346 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0373396 |
| NEK7 | NIMA-related kinase 7 | -0.0359924 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0352856 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347527 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0345075 |
| TXNRD1 | thioredoxin reductase 1 | -0.0343319 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0343008 |
| CPOX | coproporphyrinogen oxidase | -0.0328028 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0326177 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0315186 |
| KLHL24 | kelch-like family member 24 | -0.0311181 |
| ZNF292 | zinc finger protein 292 | -0.0307175 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0304545 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0300525 |
| MED13L | mediator complex subunit 13-like | -0.0299154 |
| OGA | O-GlcNAcase | -0.0291431 |
| YBX1 | Y box binding protein 1 | -0.0289888 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0288702 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0286394 |
| ECT2 | epithelial cell transforming 2 | -0.0285055 |
| TNPO1 | transportin 1 | -0.0276944 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.027075 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0267485 |
| MATR3 | matrin 3 | -0.0259273 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0253195 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.025301 |
| MGAT4C | MGAT4 family, member C | -0.0241308 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0236722 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0236684 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0235792 |
| THOC1 | THO complex 1 | -0.0233371 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0231309 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0231046 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0229862 |
| TFG | TRK-fused gene | -0.0224067 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0223309 |
| GASK1B | golgi associated kinase 1B | -0.0223185 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.022273 |
| CEP192 | centrosomal protein 192kDa | -0.0221099 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0218327 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.021656 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0216179 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0215384 |
| RBM27 | RNA binding motif protein 27 | -0.0213779 |
| HMGB2 | high mobility group box 2 | -0.0213163 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0213129 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0211809 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0211057 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.020818 |
| EDN1 | endothelin 1 | -0.0207839 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0207515 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0206714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.020608 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0203655 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.020263 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0198502 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0197064 |
| CDK19 | cyclin-dependent kinase 19 | -0.0195761 |
| CEP95 | centrosomal protein 95kDa | -0.0195175 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0193211 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0192382 |
| PREPL | prolyl endopeptidase-like | -0.0191115 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0191063 |
| RPLP1 | ribosomal protein, large, P1 | -0.0189524 |
| PTMA | prothymosin, alpha | -0.018945 |
| S100A6 | S100 calcium binding protein A6 | -0.0188704 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0188598 |
| OXR1 | oxidation resistance 1 | -0.0188386 |
| RPS24 | ribosomal protein S24 | -0.0186809 |
| ZFR | zinc finger RNA binding protein | -0.0186595 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0185472 |
| PTMS | parathymosin | -0.0183188 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0181579 |
| KIF5B | kinesin family member 5B | -0.0181551 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0181405 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0180164 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0177731 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0177443 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0176635 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0172667 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0172627 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0172418 |
| NKTR | natural killer cell triggering receptor | -0.0171591 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0171567 |
| YBX3 | Y box binding protein 3 | -0.0171213 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0165229 |
| COG5 | component of oligomeric golgi complex 5 | -0.016511 |
