| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.168497 |
| TLE4 | transducin-like enhancer of split 4 | 0.121115 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.110459 |
| FMN1 | formin 1 | 0.108288 |
| VMP1 | vacuole membrane protein 1 | 0.106868 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.102907 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.087242 |
| DST | dystonin | 0.0809989 |
| MEIS2 | Meis homeobox 2 | 0.0675623 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0637967 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0637698 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0603789 |
| GLCCI1 | glucocorticoid induced 1 | 0.0602483 |
| STK38L | serine/threonine kinase 38 like | 0.0548334 |
| FERMT2 | fermitin family member 2 | 0.0541925 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0532774 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0518568 |
| KLHL13 | kelch-like family member 13 | 0.0513129 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0499919 |
| FAM107B | family with sequence similarity 107, member B | 0.0499887 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0458696 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0446597 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0424806 |
| THBS1 | thrombospondin 1 | 0.0424596 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0424532 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.042276 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0420957 |
| DPH6 | diphthamine biosynthesis 6 | 0.0418429 |
| IGF2 | insulin-like growth factor 2 | 0.0411686 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0405829 |
| BPTF | bromodomain PHD finger transcription factor | 0.0395737 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0381 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0369268 |
| GAB2 | GRB2-associated binding protein 2 | 0.0357327 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0352587 |
| MYO1E | myosin IE | 0.034774 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0333171 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0331149 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0329652 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0327872 |
| FHL2 | four and a half LIM domains 2 | 0.0327673 |
| SIK2 | salt-inducible kinase 2 | 0.0324129 |
| PRKCA | protein kinase C, alpha | 0.0323244 |
| SYT1 | synaptotagmin I | 0.0320902 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0318765 |
| VEGFA | vascular endothelial growth factor A | 0.031708 |
| TENM1 | teneurin transmembrane protein 1 | 0.0315351 |
| HMBOX1 | homeobox containing 1 | 0.0314849 |
| MRTFA | myocardin related transcription factor A | 0.0314633 |
| PDE10A | phosphodiesterase 10A | 0.0312905 |
| ITGAV | integrin, alpha V | 0.0310424 |
| ACTN1 | actinin, alpha 1 | 0.0309858 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0306869 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0302188 |
| PLPP1 | phospholipid phosphatase 1 | 0.0301733 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0301222 |
| INTS6 | integrator complex subunit 6 | 0.0294011 |
| HOMER1 | homer scaffolding protein 1 | 0.0293664 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0291742 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0286899 |
| EGR1 | early growth response 1 | 0.0286147 |
| SYNPO2 | synaptopodin 2 | 0.028178 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0279813 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | 0.0279166 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0278919 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0278134 |
| IRS1 | insulin receptor substrate 1 | 0.0274464 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0271692 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0270215 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0268922 |
| RALYL | RALY RNA binding protein-like | 0.0264104 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0263289 |
| PTEN | phosphatase and tensin homolog | 0.026112 |
| RGS4 | regulator of G-protein signaling 4 | 0.0260145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0259526 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0254776 |
| TCF12 | transcription factor 12 | 0.025387 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0252067 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0250053 |
| PCBP2 | poly(rC) binding protein 2 | 0.024826 |
| PALLD | palladin, cytoskeletal associated protein | 0.0245265 |
| NEK1 | NIMA-related kinase 1 | 0.0242082 |
| EPHA7 | EPH receptor A7 | 0.0239332 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0237248 |
| MYO6 | myosin VI | 0.0236601 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0235883 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0233344 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0228417 |
| FLNA | filamin A, alpha | 0.0228409 |
| BRD2 | bromodomain containing 2 | 0.0225552 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0220765 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0220346 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0219517 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0219416 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0218282 |
| HDX | highly divergent homeobox | 0.0218265 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0216415 |
| AMOTL1 | angiomotin like 1 | 0.0211417 |
| ENAH | enabled homolog (Drosophila) | 0.0211151 |
| PCDH10 | protocadherin 10 | 0.020899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.155714 |
| NRG1 | neuregulin 1 | -0.126695 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0975966 |
| VIM | vimentin | -0.0945088 |
| COL1A1 | collagen, type I, alpha 1 | -0.0911846 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0896824 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0878677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0836368 |
| RPL23 | ribosomal protein L23 | -0.0783338 |
| RPS24 | ribosomal protein S24 | -0.0766836 |
| RPL35A | ribosomal protein L35a | -0.0764114 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0743054 |
| RPL38 | ribosomal protein L38 | -0.0678795 |
| LPIN1 | lipin 1 | -0.0673682 |
| RPS6 | ribosomal protein S6 | -0.0617922 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0592326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0578796 |
| RPLP1 | ribosomal protein, large, P1 | -0.0566955 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0558977 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0549722 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0528349 |
| RPL31 | ribosomal protein L31 | -0.0527341 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.051518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0507376 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0503887 |
| TMSB10 | thymosin beta 10 | -0.0478312 |
| ACTG1 | actin gamma 1 | -0.0474273 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0470181 |
| GNAS | GNAS complex locus | -0.0462171 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0450579 |
| H3-3B | H3.3 histone B | -0.0445237 |
| IER3 | immediate early response 3 | -0.0440587 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0438868 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0435447 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0431308 |
| GPC5 | glypican 5 | -0.0427241 |
| HIP1 | huntingtin interacting protein 1 | -0.0411657 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0408931 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0407147 |
| RPL34 | ribosomal protein L34 | -0.0406253 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.040277 |
| MEF2A | myocyte enhancer factor 2A | -0.0393135 |
| EGFR | epidermal growth factor receptor | -0.03796 |
| CCNI | cyclin I | -0.037714 |
| RPS21 | ribosomal protein S21 | -0.0376965 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0375311 |
| COL3A1 | collagen, type III, alpha 1 | -0.0373569 |
| NDRG1 | N-myc downstream regulated 1 | -0.0358253 |
| CUX1 | cut-like homeobox 1 | -0.0355634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0346224 |
| RPL37A | ribosomal protein L37a | -0.0344614 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0342666 |
| RPLP0 | ribosomal protein, large, P0 | -0.0338165 |
| CCND1 | cyclin D1 | -0.0334698 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0326146 |
| RPL12 | ribosomal protein L12 | -0.0324276 |
| MSI2 | musashi RNA-binding protein 2 | -0.0321535 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0315921 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0315188 |
| RPS29 | ribosomal protein S29 | -0.031294 |
| RTN4 | reticulon 4 | -0.031214 |
| RPL19 | ribosomal protein L19 | -0.0311772 |
| AHNAK | AHNAK nucleoprotein | -0.0305428 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0295825 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0293365 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0290655 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289007 |
| CADM2 | cell adhesion molecule 2 | -0.0288481 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0285539 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0285514 |
| NBEA | neurobeachin | -0.0282479 |
| RPL37 | ribosomal protein L37 | -0.0281998 |
| RSF1 | remodeling and spacing factor 1 | -0.0279498 |
| CNTN4 | contactin 4 | -0.0277394 |
| CEP350 | centrosomal protein 350kDa | -0.0277368 |
| RPS14 | ribosomal protein S14 | -0.0275633 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0271232 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0270169 |
| GDF15 | growth differentiation factor 15 | -0.0269561 |
| MXI1 | MAX interactor 1, dimerization protein | -0.026946 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0266031 |
| FTL | ferritin, light polypeptide | -0.0266007 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0265156 |
| USP36 | ubiquitin specific peptidase 36 | -0.0264937 |
| COL4A5 | collagen, type IV, alpha 5 | -0.026321 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0263163 |
| SEPTIN9 | septin 9 | -0.0261623 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0260879 |
| CALU | calumenin | -0.0260824 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.026065 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0260325 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0259713 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0259136 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0258904 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.025765 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0257134 |
| RPL36A | ribosomal protein L36a | -0.0253579 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.025329 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0252334 |
| ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif, 19 | -0.0251846 |
