| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.209961 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.135989 |
| SMAD3 | SMAD family member 3 | 0.132597 |
| RNF213 | ring finger protein 213 | 0.131073 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.124066 |
| VCL | vinculin | 0.107773 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.107151 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0986775 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0955978 |
| MYO1E | myosin IE | 0.0938764 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0932914 |
| INTS6 | integrator complex subunit 6 | 0.0883717 |
| ANXA2 | annexin A2 | 0.0838441 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0793765 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0760054 |
| SP100 | SP100 nuclear antigen | 0.0753046 |
| MX1 | MX dynamin-like GTPase 1 | 0.07402 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0731398 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0721032 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0719666 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0709723 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0701435 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0698803 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0694168 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0691186 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0660003 |
| RIGI | RNA sensor RIG-I | 0.0657569 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0607388 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0585776 |
| MX2 | MX dynamin-like GTPase 2 | 0.0584503 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0573992 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0560174 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0551478 |
| ETV6 | ets variant 6 | 0.0549602 |
| TJP1 | tight junction protein 1 | 0.0545416 |
| VMP1 | vacuole membrane protein 1 | 0.0539439 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0533407 |
| PLSCR1 | phospholipid scramblase 1 | 0.0532959 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0521651 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0517596 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0496111 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0490065 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0486654 |
| ASPH | aspartate beta-hydroxylase | 0.0474835 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0473748 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0467973 |
| ERBIN | erbb2 interacting protein | 0.0464254 |
| SPATA13 | spermatogenesis associated 13 | 0.0463044 |
| BCL2L1 | BCL2-like 1 | 0.0440258 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0436581 |
| RAD51B | RAD51 paralog B | 0.0435321 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.043008 |
| PRKCA | protein kinase C, alpha | 0.0417271 |
| LCN2 | lipocalin 2 | 0.0404459 |
| MCU | mitochondrial calcium uniporter | 0.0401708 |
| KYNU | kynureninase | 0.0400165 |
| EFNB2 | ephrin-B2 | 0.0395204 |
| MAP7 | microtubule-associated protein 7 | 0.0394295 |
| PLSCR2 | phospholipid scramblase 2 | 0.0389173 |
| ITGA6 | integrin, alpha 6 | 0.0377122 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0375056 |
| TMC5 | transmembrane channel-like 5 | 0.0373081 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0371421 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0365781 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0363693 |
| MSI2 | musashi RNA-binding protein 2 | 0.0363089 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0354546 |
| DIAPH1 | diaphanous-related formin 1 | 0.0346799 |
| RAB7A | RAB7A, member RAS oncogene family | 0.034106 |
| POF1B | premature ovarian failure, 1B | 0.0337278 |
| PHF3 | PHD finger protein 3 | 0.0335335 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0333816 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.033177 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0331269 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0328376 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0327517 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0318842 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0317771 |
| FNIP2 | folliculin interacting protein 2 | 0.0317192 |
| FAT1 | FAT atypical cadherin 1 | 0.0312611 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.031228 |
| STK24 | serine/threonine kinase 24 | 0.0312038 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0310148 |
| XAF1 | XIAP associated factor 1 | 0.0309461 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0307115 |
| DUSP10 | dual specificity phosphatase 10 | 0.0303894 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0303705 |
| HKDC1 | hexokinase domain containing 1 | 0.0300853 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0298781 |
| MLPH | melanophilin | 0.0297927 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0297348 |
| DST | dystonin | 0.0297088 |
| PDLIM5 | PDZ and LIM domain 5 | 0.029644 |
| FMN1 | formin 1 | 0.0295453 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0295247 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294474 |
| JAK1 | Janus kinase 1 | 0.029436 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0292385 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0286894 |
| ATP11A | ATPase, class VI, type 11A | 0.028537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.171175 |
| NDRG1 | N-myc downstream regulated 1 | -0.0940868 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.091209 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0877 |
| B2M | beta-2-microglobulin | -0.0835748 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0759603 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0756569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733029 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0664532 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0610616 |
| PTMA | prothymosin, alpha | -0.0565897 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0546508 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.05384 |
| TXNIP | thioredoxin interacting protein | -0.0509061 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0455659 |
| RNF149 | ring finger protein 149 | -0.0454089 |
| HLA-B | major histocompatibility complex, class I, B | -0.0448821 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0438293 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.04263 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421493 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0418484 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0407638 |
| GOLGA4 | golgin A4 | -0.0407583 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0406841 |
| RPL35A | ribosomal protein L35a | -0.0405828 |
| MT2A | metallothionein 2A | -0.0399523 |
| RPS6 | ribosomal protein S6 | -0.038738 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0382105 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0366545 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0354945 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.035488 |
| PTEN | phosphatase and tensin homolog | -0.0350022 |
| CALR | calreticulin | -0.0349634 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0347927 |
| SEC24D | SEC24 family member D | -0.0347428 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0340835 |
| WDR45B | WD repeat domain 45B | -0.0339784 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0338161 |
| AHI1 | Abelson helper integration site 1 | -0.033239 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0331186 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0328423 |
| MORF4L2 | mortality factor 4 like 2 | -0.032738 |
| CANX | calnexin | -0.0311494 |
| RPLP1 | ribosomal protein, large, P1 | -0.0310276 |
| COG6 | component of oligomeric golgi complex 6 | -0.0309135 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0305508 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0304027 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0303884 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0303419 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0300032 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0297698 |
| HLA-A | major histocompatibility complex, class I, A | -0.0297679 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0296718 |
| GNAS | GNAS complex locus | -0.0295209 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0288117 |
| NUCB2 | nucleobindin 2 | -0.0286479 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0284308 |
| AGR2 | anterior gradient 2 | -0.0280717 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0276929 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0273367 |
| TMSB10 | thymosin beta 10 | -0.0272664 |
| DSTN | destrin (actin depolymerizing factor) | -0.0270388 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0265424 |
| ADM | adrenomedullin | -0.0261583 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0260138 |
| DIAPH3 | diaphanous-related formin 3 | -0.0259461 |
| RPL12 | ribosomal protein L12 | -0.0254542 |
| CSTB | cystatin B (stefin B) | -0.0251878 |
| UBC | ubiquitin C | -0.0250607 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0249463 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0249265 |
| CALU | calumenin | -0.0247735 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0246471 |
| CCNL1 | cyclin L1 | -0.024382 |
| S100A10 | S100 calcium binding protein A10 | -0.0242757 |
| TFG | TRK-fused gene | -0.0242319 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0241779 |
| TMEM263 | transmembrane protein 263 | -0.0241575 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0241555 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0241038 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0239677 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0239429 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0238602 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0237293 |
| SEC24A | SEC24 family member A | -0.0236571 |
| RPS8 | ribosomal protein S8 | -0.0236056 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0234582 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0234487 |
| EHF | ets homologous factor | -0.0232122 |
| SBF2 | SET binding factor 2 | -0.0230549 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0230229 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0229801 |
| TPR | translocated promoter region, nuclear basket protein | -0.0227788 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0227707 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0227408 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0226968 |
| HM13 | histocompatibility (minor) 13 | -0.0225675 |
| ZNF395 | zinc finger protein 395 | -0.0224465 |
| KLHL24 | kelch-like family member 24 | -0.022443 |
