| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.0933317 |
| FAT1 | FAT atypical cadherin 1 | 0.0906537 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0886695 |
| LMO7 | LIM domain 7 | 0.0749286 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0505345 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0446515 |
| RPS12 | ribosomal protein S12 | 0.0433812 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0433718 |
| LDHA | lactate dehydrogenase A | 0.0425067 |
| B2M | beta-2-microglobulin | 0.0408595 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0400926 |
| SVIL | supervillin | 0.0395338 |
| MT2A | metallothionein 2A | 0.0394146 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.035519 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0354023 |
| ONECUT3 | one cut homeobox 3 | 0.0350488 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0332117 |
| SQSTM1 | sequestosome 1 | 0.0331711 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0326285 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322256 |
| LAMA4 | laminin, alpha 4 | 0.032053 |
| EGFR | epidermal growth factor receptor | 0.0318168 |
| RIGI | RNA sensor RIG-I | 0.031789 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0311745 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0305088 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299715 |
| POF1B | premature ovarian failure, 1B | 0.029434 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0289127 |
| MYO5B | myosin VB | 0.0286643 |
| ASPH | aspartate beta-hydroxylase | 0.0281638 |
| RPL3 | ribosomal protein L3 | 0.0278193 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0277571 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0274875 |
| RPS2 | ribosomal protein S2 | 0.0273215 |
| RPL37A | ribosomal protein L37a | 0.027059 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0268085 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0262592 |
| GOLGB1 | golgin B1 | 0.0261902 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0252339 |
| SEPTIN9 | septin 9 | 0.0248978 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0248843 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0248559 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0248113 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0246089 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0241402 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0241146 |
| MUC13 | mucin 13, cell surface associated | 0.0239338 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0238621 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231867 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0223813 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0221629 |
| SMAD2 | SMAD family member 2 | 0.0220969 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0216872 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0214811 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213967 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0213881 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.021111 |
| CALR | calreticulin | 0.0209574 |
| INTS6 | integrator complex subunit 6 | 0.0206963 |
| CD47 | CD47 molecule | 0.0206709 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.020625 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0205646 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0202786 |
| CUX1 | cut-like homeobox 1 | 0.0202137 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0199611 |
| NEBL | nebulette | 0.0197708 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0195385 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0195338 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0195065 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0192828 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0188006 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0187353 |
| DUSP16 | dual specificity phosphatase 16 | 0.0184987 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0184554 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0182418 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0177157 |
| BRD2 | bromodomain containing 2 | 0.0176073 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0175169 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0174677 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0171854 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0170295 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0169834 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0169121 |
| HYOU1 | hypoxia up-regulated 1 | 0.0166324 |
| RPS27A | ribosomal protein S27a | 0.0165833 |
| CD44 | CD44 molecule (Indian blood group) | 0.0165104 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0164349 |
| CTSB | cathepsin B | 0.016386 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0163292 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0162594 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0162308 |
| SMAD3 | SMAD family member 3 | 0.0161324 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0160596 |
| FBXO11 | F-box protein 11 | 0.0160571 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0160529 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0159885 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0159062 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0158987 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0158688 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0158552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.173939 |
| TMSB10 | thymosin beta 10 | -0.151452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137347 |
| NPSR1 | neuropeptide S receptor 1 | -0.133923 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.121249 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113358 |
| TXNIP | thioredoxin interacting protein | -0.105789 |
| S100A6 | S100 calcium binding protein A6 | -0.105076 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.10464 |
| NDRG1 | N-myc downstream regulated 1 | -0.103406 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0799315 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0762711 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0747229 |
| MED13L | mediator complex subunit 13-like | -0.0699003 |
| FAM13A | family with sequence similarity 13, member A | -0.0697583 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0688688 |
| TNS4 | tensin 4 | -0.0687019 |
| EPCAM | epithelial cell adhesion molecule | -0.0682603 |
| RPLP0 | ribosomal protein, large, P0 | -0.0677875 |
| ZNF292 | zinc finger protein 292 | -0.0677134 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0645143 |
| ANXA2 | annexin A2 | -0.0633617 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0628361 |
| RPL35A | ribosomal protein L35a | -0.0625357 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0623312 |
| GPHN | gephyrin | -0.0617238 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0592535 |
| PERP | PERP, TP53 apoptosis effector | -0.0584079 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0581537 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0577899 |
| RPL34 | ribosomal protein L34 | -0.057089 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0568516 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0563035 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0547267 |
| HMGA1 | high mobility group AT-hook 1 | -0.0538589 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0522533 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0521466 |
| CALB1 | calbindin 1, 28kDa | -0.0507112 |
| SETD5 | SET domain containing 5 | -0.0496156 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0495539 |
| FLNB | filamin B, beta | -0.048961 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.047993 |
| PIGR | polymeric immunoglobulin receptor | -0.0461926 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0457996 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0452694 |
| RPS6 | ribosomal protein S6 | -0.0450797 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0444635 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0434489 |
| NFIA | nuclear factor I/A | -0.0433616 |
| CCNY | cyclin Y | -0.0433264 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0432963 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0428663 |
| MLEC | malectin | -0.0428515 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0427452 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0424316 |
| EZR | ezrin | -0.0420414 |
| CBX3 | chromobox homolog 3 | -0.0419379 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0419253 |
| KRT19 | keratin 19, type I | -0.0409804 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0409492 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0404752 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0402978 |
| ITGA6 | integrin, alpha 6 | -0.0400066 |
| INSIG1 | insulin induced gene 1 | -0.0395633 |
| RPS19 | ribosomal protein S19 | -0.0394965 |
| USP3 | ubiquitin specific peptidase 3 | -0.0390362 |
| RPL11 | ribosomal protein L11 | -0.0387619 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0382611 |
| SPPL3 | signal peptide peptidase like 3 | -0.0382444 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0382406 |
| RAB6A | RAB6A, member RAS oncogene family | -0.037999 |
| RPL12 | ribosomal protein L12 | -0.0379973 |
| FNBP1L | formin binding protein 1-like | -0.0379825 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0378916 |
| RPLP1 | ribosomal protein, large, P1 | -0.0378141 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0376487 |
| FERMT1 | fermitin family member 1 | -0.0374661 |
| EREG | epiregulin | -0.0374625 |
| DEK | DEK proto-oncogene | -0.03728 |
| CCNI | cyclin I | -0.0368137 |
| EXOC1 | exocyst complex component 1 | -0.0366559 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0364631 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0358792 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.035526 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0352898 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0351981 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0350805 |
| PRSS3 | protease, serine, 3 | -0.0350783 |
| S100A10 | S100 calcium binding protein A10 | -0.0349449 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0344219 |
| AHNAK | AHNAK nucleoprotein | -0.034286 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0340308 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0338027 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0336954 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0335434 |
| PFN1 | profilin 1 | -0.0332513 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0330685 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329302 |
| RSF1 | remodeling and spacing factor 1 | -0.0325604 |
| AGR2 | anterior gradient 2 | -0.0324782 |
