| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.150339 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.114611 |
| TP63 | tumor protein p63 | 0.10427 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0976965 |
| HLA-B | major histocompatibility complex, class I, B | 0.0840046 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0763246 |
| CD44 | CD44 molecule (Indian blood group) | 0.0747999 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0682061 |
| RPS12 | ribosomal protein S12 | 0.0614526 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0612095 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0593564 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0587667 |
| SP100 | SP100 nuclear antigen | 0.0557209 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0530132 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0522616 |
| RPL37A | ribosomal protein L37a | 0.0512545 |
| RPL26 | ribosomal protein L26 | 0.0508231 |
| HDAC9 | histone deacetylase 9 | 0.050513 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0488141 |
| PDE10A | phosphodiesterase 10A | 0.0487019 |
| TNS3 | tensin 3 | 0.0482396 |
| CADM2 | cell adhesion molecule 2 | 0.0465603 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0452804 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0426881 |
| RPS27A | ribosomal protein S27a | 0.0424545 |
| CAPRIN2 | caprin family member 2 | 0.0422253 |
| RPS3 | ribosomal protein S3 | 0.0409021 |
| EHBP1 | EH domain binding protein 1 | 0.0407291 |
| INTS6 | integrator complex subunit 6 | 0.0394906 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0388076 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0385975 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0383032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0379317 |
| RIGI | RNA sensor RIG-I | 0.0373066 |
| RPS8 | ribosomal protein S8 | 0.0368961 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0364091 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0354858 |
| RPL31 | ribosomal protein L31 | 0.0353263 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0346886 |
| EFNA5 | ephrin-A5 | 0.0338968 |
| AEBP2 | AE binding protein 2 | 0.0335874 |
| PRELID2 | PRELI domain containing 2 | 0.0335714 |
| PLSCR1 | phospholipid scramblase 1 | 0.0330984 |
| SQSTM1 | sequestosome 1 | 0.032566 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0324336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0319358 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0318169 |
| RUNX1 | runt-related transcription factor 1 | 0.0316842 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0310026 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0309675 |
| NEK10 | NIMA-related kinase 10 | 0.0300654 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0288353 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0286645 |
| PMP22 | peripheral myelin protein 22 | 0.0284741 |
| FMNL2 | formin-like 2 | 0.0283513 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0279552 |
| RAD51B | RAD51 paralog B | 0.0270958 |
| DNER | delta/notch-like EGF repeat containing | 0.0270561 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0269011 |
| MYOF | myoferlin | 0.0264041 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0262702 |
| VCL | vinculin | 0.0262599 |
| HOMER1 | homer scaffolding protein 1 | 0.0262511 |
| RNF213 | ring finger protein 213 | 0.0261628 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0260541 |
| RPL12 | ribosomal protein L12 | 0.0256085 |
| B2M | beta-2-microglobulin | 0.0254905 |
| EPHA4 | EPH receptor A4 | 0.0250037 |
| GOLGB1 | golgin B1 | 0.0244798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0244403 |
| RPS6 | ribosomal protein S6 | 0.0236983 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.023513 |
| KLF6 | Kruppel-like factor 6 | 0.0230975 |
| HLA-E | major histocompatibility complex, class I, E | 0.0229801 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0226424 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0226291 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0225548 |
| RPS17 | ribosomal protein S17 | 0.0221941 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0218802 |
| STK17A | serine/threonine kinase 17a | 0.0217594 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0215723 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0215287 |
| RPL37 | ribosomal protein L37 | 0.0207589 |
| DPH6 | diphthamine biosynthesis 6 | 0.020734 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0207338 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.020684 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0200489 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0199823 |
| RPS29 | ribosomal protein S29 | 0.0198479 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0195701 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0193964 |
| LDHA | lactate dehydrogenase A | 0.0192917 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0191444 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0190449 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0190232 |
| PTMA | prothymosin, alpha | 0.0188727 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0188625 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0188551 |
| TGM2 | transglutaminase 2 | 0.0188264 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0185848 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.116851 |
| MT2A | metallothionein 2A | -0.0987472 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0963051 |
| POTEF | POTE ankyrin domain family, member F | -0.0879839 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0608757 |
| TMSB10 | thymosin beta 10 | -0.0540339 |
| RTN4 | reticulon 4 | -0.0521804 |
| RAI1 | retinoic acid induced 1 | -0.048126 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0458144 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0453612 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0396216 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0392232 |
| CENPF | centromere protein F, 350/400kDa | -0.0390165 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0385574 |
| ACTG1 | actin gamma 1 | -0.0363685 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0357574 |
| TMEM41B | transmembrane protein 41B | -0.0344345 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0322645 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0320939 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0319553 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0311767 |
| EZR | ezrin | -0.0309135 |
| MKI67 | marker of proliferation Ki-67 | -0.0301839 |
| FTL | ferritin, light polypeptide | -0.029661 |
| XPO1 | exportin 1 | -0.0294052 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0292318 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0286432 |
| FOSL1 | FOS-like antigen 1 | -0.0282687 |
| MT1X | metallothionein 1X | -0.0278244 |
| RBM25 | RNA binding motif protein 25 | -0.027718 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0276808 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0276037 |
| SRGN | serglycin | -0.0270812 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0268884 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0267849 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0263428 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0261409 |
| HMGA1 | high mobility group AT-hook 1 | -0.0240825 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0239794 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0239308 |
| CEP170 | centrosomal protein 170kDa | -0.0237691 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0237472 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0237422 |
| S100A6 | S100 calcium binding protein A6 | -0.023715 |
| SEPTIN7 | septin 7 | -0.0236478 |
| YBX1 | Y box binding protein 1 | -0.0236283 |
| RRM2 | ribonucleotide reductase M2 | -0.0230263 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0226645 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0224403 |
| EGR1 | early growth response 1 | -0.0223579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0221523 |
| YBX3 | Y box binding protein 3 | -0.0219873 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0217888 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0215559 |
| PGK1 | phosphoglycerate kinase 1 | -0.0214957 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0207409 |
| TPX2 | TPX2, microtubule-associated | -0.020518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0201571 |
| ECT2 | epithelial cell transforming 2 | -0.0200751 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0199782 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0197049 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.019649 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0196099 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.019545 |
| RPL5 | ribosomal protein L5 | -0.0194724 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0192604 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0192081 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0191565 |
| PKM | pyruvate kinase, muscle | -0.019144 |
| PCBP2 | poly(rC) binding protein 2 | -0.0190784 |
| WDR45B | WD repeat domain 45B | -0.0189839 |
| SBF2 | SET binding factor 2 | -0.018983 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0188936 |
| DIAPH3 | diaphanous-related formin 3 | -0.0185734 |
| JMJD1C | jumonji domain containing 1C | -0.0185102 |
| OLA1 | Obg-like ATPase 1 | -0.0183748 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0181914 |
| SRPK2 | SRSF protein kinase 2 | -0.0181152 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0181045 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0180607 |
| ANLN | anillin, actin binding protein | -0.0180567 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0176307 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.017346 |
| SGO2 | shugoshin 2 | -0.0172229 |
| WDR26 | WD repeat domain 26 | -0.0169315 |
| KIF14 | kinesin family member 14 | -0.0168641 |
| EMP1 | epithelial membrane protein 1 | -0.0168195 |
| PRDX1 | peroxiredoxin 1 | -0.0168184 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0167336 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0167149 |
| NUP58 | nucleoporin 58 | -0.0166918 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0166408 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0166286 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0163419 |
| S100A10 | S100 calcium binding protein A10 | -0.0163373 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0163194 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0163193 |
| TNPO1 | transportin 1 | -0.0161986 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0161202 |
| ANXA1 | annexin A1 | -0.0160604 |
