| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.214609 |
| CD44 | CD44 molecule (Indian blood group) | 0.101872 |
| FN1 | fibronectin 1 | 0.0959998 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0889062 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0794175 |
| KYNU | kynureninase | 0.0619812 |
| ASPH | aspartate beta-hydroxylase | 0.0570743 |
| GLIS3 | GLIS family zinc finger 3 | 0.0565883 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0562664 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0552306 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0521674 |
| MEF2A | myocyte enhancer factor 2A | 0.0514505 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.048833 |
| CALD1 | caldesmon 1 | 0.0480737 |
| ANKRD11 | ankyrin repeat domain 11 | 0.047752 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0425252 |
| PDLIM5 | PDZ and LIM domain 5 | 0.040921 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0406654 |
| RPL11 | ribosomal protein L11 | 0.0387697 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0370933 |
| NAV1 | neuron navigator 1 | 0.0370217 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0360181 |
| RPL37A | ribosomal protein L37a | 0.0358164 |
| PRELID2 | PRELI domain containing 2 | 0.0356756 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335766 |
| FUS | FUS RNA binding protein | 0.0332252 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0326558 |
| PTMA | prothymosin, alpha | 0.0322057 |
| WWOX | WW domain containing oxidoreductase | 0.0313364 |
| INTS6 | integrator complex subunit 6 | 0.0311558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309967 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0309308 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0304781 |
| ANXA2 | annexin A2 | 0.0298966 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0293674 |
| ZNF292 | zinc finger protein 292 | 0.0293301 |
| GSE1 | Gse1 coiled-coil protein | 0.0289069 |
| VMP1 | vacuole membrane protein 1 | 0.0282606 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0281126 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0280052 |
| SETBP1 | SET binding protein 1 | 0.0279044 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0276528 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0276393 |
| RUNX1 | runt-related transcription factor 1 | 0.0267905 |
| RPS12 | ribosomal protein S12 | 0.0259429 |
| TBCA | tubulin folding cofactor A | 0.0258007 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0253664 |
| JMJD1C | jumonji domain containing 1C | 0.0252724 |
| RPS6 | ribosomal protein S6 | 0.025246 |
| RACK1 | receptor for activated C kinase 1 | 0.0252363 |
| EXOC4 | exocyst complex component 4 | 0.0252084 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0251447 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0251293 |
| MED13L | mediator complex subunit 13-like | 0.0250264 |
| ENO1 | enolase 1, (alpha) | 0.0249759 |
| VIM | vimentin | 0.0249265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248029 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0244628 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0243685 |
| PTK2 | protein tyrosine kinase 2 | 0.0242973 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0240962 |
| RPL5 | ribosomal protein L5 | 0.0238626 |
| SMYD3 | SET and MYND domain containing 3 | 0.0237745 |
| ECE1 | endothelin converting enzyme 1 | 0.0237665 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.02371 |
| TPM4 | tropomyosin 4 | 0.0233837 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0232045 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0231092 |
| SYNJ2 | synaptojanin 2 | 0.0230904 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0230662 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0229705 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0228923 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0226833 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0226043 |
| CLIC4 | chloride intracellular channel 4 | 0.0225232 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0223325 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0222479 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0221626 |
| ZNF638 | zinc finger protein 638 | 0.0221409 |
| FAT1 | FAT atypical cadherin 1 | 0.0219512 |
| DST | dystonin | 0.0218621 |
| FAM20C | family with sequence similarity 20, member C | 0.0217548 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0216744 |
| AUTS2 | autism susceptibility candidate 2 | 0.0216319 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0215019 |
| SP100 | SP100 nuclear antigen | 0.0213951 |
| BSG | basigin (Ok blood group) | 0.0212936 |
| EHBP1 | EH domain binding protein 1 | 0.0210118 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0210037 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0209652 |
| RPL34 | ribosomal protein L34 | 0.0208545 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0207869 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0207664 |
| KLF10 | Kruppel-like factor 10 | 0.0204796 |
| PHIP | pleckstrin homology domain interacting protein | 0.0204672 |
| VCL | vinculin | 0.0201335 |
| RAD51B | RAD51 paralog B | 0.0199531 |
| RYBP | RING1 and YY1 binding protein | 0.0199479 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0199402 |
| SQSTM1 | sequestosome 1 | 0.0198828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.210483 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.168244 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0925096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0837218 |
| COL1A2 | collagen, type I, alpha 2 | -0.0799875 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0710913 |
| CALU | calumenin | -0.0644649 |
| TMEM165 | transmembrane protein 165 | -0.0570063 |
| GOLGA4 | golgin A4 | -0.0568862 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0509508 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0507575 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0468822 |
| IL6 | interleukin 6 | -0.0456445 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.04349 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0411884 |
| CDH13 | cadherin 13 | -0.0410233 |
| LOX | lysyl oxidase | -0.0404886 |
| CDK13 | cyclin-dependent kinase 13 | -0.0394345 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0376506 |
| COL5A2 | collagen, type V, alpha 2 | -0.0364542 |
| LAMB3 | laminin, beta 3 | -0.0361921 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0359604 |
| ARF4 | ADP-ribosylation factor 4 | -0.0347911 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0334788 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0330182 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.032325 |
| CLINT1 | clathrin interactor 1 | -0.0322291 |
| NDRG1 | N-myc downstream regulated 1 | -0.0318985 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0316063 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0315477 |
| TNPO3 | transportin 3 | -0.0313155 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0307561 |
| KAZN | kazrin, periplakin interacting protein | -0.0300818 |
| NBAS | neuroblastoma amplified sequence | -0.0300735 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.029652 |
| SRP54 | signal recognition particle 54kDa | -0.0293818 |
| ATP13A3 | ATPase type 13A3 | -0.029308 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0292628 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0291585 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0282648 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0282434 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282049 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0280716 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0272196 |
| CANX | calnexin | -0.0270396 |
| RHEB | Ras homolog enriched in brain | -0.026985 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.0265077 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0265072 |
| SCFD2 | sec1 family domain containing 2 | -0.02636 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0261361 |
| UBC | ubiquitin C | -0.0259005 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0256347 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0251919 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0251676 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0245802 |
| MYADM | myeloid-associated differentiation marker | -0.0240434 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0235827 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0234117 |
| SETD5 | SET domain containing 5 | -0.0232854 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0232353 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0231754 |
| CADM1 | cell adhesion molecule 1 | -0.0230036 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0225818 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0225358 |
| TFG | TRK-fused gene | -0.0221916 |
| SCARB2 | scavenger receptor class B, member 2 | -0.021873 |
| SERINC3 | serine incorporator 3 | -0.0217549 |
| ARRDC3 | arrestin domain containing 3 | -0.0215375 |
| SEC24A | SEC24 family member A | -0.0215274 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0211693 |
| KLHDC10 | kelch domain containing 10 | -0.0210962 |
| COPA | coatomer protein complex, subunit alpha | -0.0210427 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0209417 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0208319 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.020733 |
| DIAPH3 | diaphanous-related formin 3 | -0.0205503 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0202467 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0200462 |
| TPM1 | tropomyosin 1 (alpha) | -0.020039 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0199522 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0199463 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0196606 |
| NOP58 | NOP58 ribonucleoprotein | -0.0195959 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0194977 |
| MMP12 | matrix metallopeptidase 12 | -0.0194885 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0194311 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.0194276 |
| STC1 | stanniocalcin 1 | -0.0193024 |
| RAI1 | retinoic acid induced 1 | -0.0192713 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0192603 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0192456 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0191964 |
| TULP3 | tubby like protein 3 | -0.0191184 |
| MSN | moesin | -0.0190439 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0189213 |
| FNBP4 | formin binding protein 4 | -0.0187563 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0187074 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0186156 |
| TMSB10 | thymosin beta 10 | -0.0185622 |
| RINT1 | RAD50 interactor 1 | -0.0185479 |
