| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LB-100 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LB-100_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.118438 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.117523 |
| INTS6 | integrator complex subunit 6 | 0.0933539 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0852485 |
| HMGA2 | high mobility group AT-hook 2 | 0.0785378 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0768914 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.076468 |
| LDHA | lactate dehydrogenase A | 0.0755515 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0712268 |
| DST | dystonin | 0.0702456 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0639505 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0617939 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0608367 |
| SQSTM1 | sequestosome 1 | 0.0588987 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0576346 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0559697 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0556118 |
| CD44 | CD44 molecule (Indian blood group) | 0.0478623 |
| PKM | pyruvate kinase, muscle | 0.0476377 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0468617 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0465489 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0437683 |
| SVIL | supervillin | 0.0432464 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0425851 |
| EGFR | epidermal growth factor receptor | 0.0417132 |
| PRKCA | protein kinase C, alpha | 0.0416164 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0404814 |
| TLE4 | transducin-like enhancer of split 4 | 0.0391587 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.038875 |
| POTEF | POTE ankyrin domain family, member F | 0.0384538 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0378155 |
| RIGI | RNA sensor RIG-I | 0.037632 |
| IGF2 | insulin-like growth factor 2 | 0.0373527 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0359548 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0357014 |
| PRR16 | proline rich 16 | 0.0343133 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0341935 |
| COL5A1 | collagen, type V, alpha 1 | 0.0341843 |
| SIK2 | salt-inducible kinase 2 | 0.0341089 |
| ITGB4 | integrin, beta 4 | 0.0335047 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0329963 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0324422 |
| PRSS23 | protease, serine, 23 | 0.0322572 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0321799 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0320294 |
| JAK1 | Janus kinase 1 | 0.0311948 |
| SDC4 | syndecan 4 | 0.0311105 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0310749 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0309655 |
| PCED1B | PC-esterase domain containing 1B | 0.0308613 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0307047 |
| RUNX1 | runt-related transcription factor 1 | 0.0306276 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0305624 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0305067 |
| RAI14 | retinoic acid induced 14 | 0.0301876 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0299124 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0298973 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0297523 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0297255 |
| PODXL | podocalyxin-like | 0.0296942 |
| ANGPTL4 | angiopoietin-like 4 | 0.0293276 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0288975 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0288571 |
| JUN | jun proto-oncogene | 0.0286861 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02839 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0282524 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0282335 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0281483 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0280154 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0279888 |
| ENO1 | enolase 1, (alpha) | 0.0279301 |
| SIK3 | SIK family kinase 3 | 0.0276878 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0275722 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0273835 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0273676 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0272982 |
| RNF217 | ring finger protein 217 | 0.0268595 |
| CLIC4 | chloride intracellular channel 4 | 0.0267 |
| B2M | beta-2-microglobulin | 0.0266897 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0261756 |
| GOLGB1 | golgin B1 | 0.0260687 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0259258 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0257106 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0253824 |
| KLHL29 | kelch-like family member 29 | 0.0251714 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0251663 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0251225 |
| PLEK2 | pleckstrin 2 | 0.0248247 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0247724 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0246621 |
| LMO7 | LIM domain 7 | 0.024467 |
| TRAM2 | translocation associated membrane protein 2 | 0.0243523 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0243477 |
| IRF1 | interferon regulatory factor 1 | 0.0243394 |
| SMAD3 | SMAD family member 3 | 0.0243123 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0242629 |
| MSN | moesin | 0.0240631 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0239394 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0237957 |
| MYO10 | myosin X | 0.0233517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0931952 |
| RBM39 | RNA binding motif protein 39 | -0.0849455 |
| ZNF292 | zinc finger protein 292 | -0.0683553 |
| TXNRD1 | thioredoxin reductase 1 | -0.0664623 |
| YAP1 | Yes-associated protein 1 | -0.065925 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0653549 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0647619 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0643744 |
| SMYD3 | SET and MYND domain containing 3 | -0.0631941 |
| ECT2 | epithelial cell transforming 2 | -0.0615737 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0608337 |
| CENPF | centromere protein F, 350/400kDa | -0.0606927 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0596904 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0596345 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0592113 |
| TMSB10 | thymosin beta 10 | -0.0589427 |
| TPX2 | TPX2, microtubule-associated | -0.0588778 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0579895 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0549404 |
| VIM | vimentin | -0.0532088 |
| SNX14 | sorting nexin 14 | -0.0521477 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0505978 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0505714 |
| SETD5 | SET domain containing 5 | -0.0497527 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0488539 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0488063 |
| RPL35A | ribosomal protein L35a | -0.0485374 |
| CANX | calnexin | -0.0481866 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0480828 |
| ETF1 | eukaryotic translation termination factor 1 | -0.0480217 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0476423 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0470128 |
| NUP58 | nucleoporin 58 | -0.0468016 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0465965 |
| SEPTIN7 | septin 7 | -0.0456121 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0451714 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0450272 |
| TMEM123 | transmembrane protein 123 | -0.0448173 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0446372 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0432743 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0419053 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0418845 |
| PHF20 | PHD finger protein 20 | -0.041554 |
| ANLN | anillin, actin binding protein | -0.0414608 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0408171 |
| GNAS | GNAS complex locus | -0.0402507 |
| HELZ | helicase with zinc finger | -0.0401673 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0400603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0398951 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.039424 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0393545 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0390189 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.038647 |
| DEK | DEK proto-oncogene | -0.0386432 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0384275 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0382723 |
| NOP58 | NOP58 ribonucleoprotein | -0.037549 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0374445 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0373333 |
| MT2A | metallothionein 2A | -0.0370974 |
| RPLP1 | ribosomal protein, large, P1 | -0.0368506 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0364696 |
| WDR45B | WD repeat domain 45B | -0.0363351 |
| KIAA1328 | KIAA1328 | -0.036293 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0360766 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0357876 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.035697 |
| SGO2 | shugoshin 2 | -0.0356516 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0355344 |
| XPO1 | exportin 1 | -0.0354415 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0353692 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0353567 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0351041 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0346483 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0342785 |
| RRBP1 | ribosome binding protein 1 | -0.0342374 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0341144 |
| HJURP | Holliday junction recognition protein | -0.0340096 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0339571 |
| GOLT1B | golgi transport 1B | -0.0336489 |
| HMGB2 | high mobility group box 2 | -0.0336301 |
| OSMR | oncostatin M receptor | -0.0333613 |
| MATR3 | matrin 3 | -0.0332422 |
| RPL30 | ribosomal protein L30 | -0.0332028 |
| KIF4A | kinesin family member 4A | -0.0329483 |
| SRP54 | signal recognition particle 54kDa | -0.0328703 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0328078 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0321836 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321741 |
| PRR11 | proline rich 11 | -0.0320981 |
| RPL4 | ribosomal protein L4 | -0.0316768 |
| PHIP | pleckstrin homology domain interacting protein | -0.0316622 |
| CUL3 | cullin 3 | -0.0315998 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0315341 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0314468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0312581 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0311552 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0311279 |
| FAF2 | Fas associated factor family member 2 | -0.0310062 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0309127 |
