LBP Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description lipopolysaccharide binding protein|The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 3929)
External Link http://www.ncbi.nlm.nih.gov/gene/3929
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76 interacting proteins for LBP from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
A2M alpha-2-macroglobulin
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOM apolipoprotein M
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BAG6 BCL2-associated athanogene 6
BST1 bone marrow stromal cell antigen 1
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C6 complement component 6
C9 complement component 9
CAMP cathelicidin antimicrobial peptide
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD14 CD14 molecule
CD5L CD5 molecule-like
CFB complement factor B
CFH complement factor H
CFHR1 complement factor H-related 1
CLU clusterin
COL6A6 collagen, type VI, alpha 6
CP ceruloplasmin (ferroxidase)
EPYC epiphycan
F2 coagulation factor II (thrombin)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
GC group-specific component (vitamin D binding protein)
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HRG histidine-rich glycoprotein
HSPB1 heat shock 27kDa protein 1
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IRF6 interferon regulatory factor 6
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIAA0753 KIAA0753
KIRREL kin of IRRE like (Drosophila)
KNG1 kininogen 1
LUM lumican
OPTN optineurin
PLG plasminogen
PON1 paraoxonase 1
PRDX4 peroxiredoxin 4
PROS1 protein S (alpha)
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PYCRL pyrroline-5-carboxylate reductase-like
RPS21 ribosomal protein S21
SAA2 serum amyloid A2
SAA4 serum amyloid A4, constitutive
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SETD1A SET domain containing 1A
SHBG sex hormone-binding globulin
SMAD3 SMAD family member 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM33 tripartite motif containing 33
TSC22D4 TSC22 domain family, member 4
TTR transthyretin
VTN vitronectin