LCLC-97TM1 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma, large cell (Cell Line Ontology, CLO_0007283)
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124 genes mutated in the LCLC-97TM1 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACTN4 actinin, alpha 4
ADD1 adducin 1 (alpha)
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
ARHGAP22 Rho GTPase activating protein 22
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AVL9 AVL9 homolog (S. cerevisiase)
BAIAP2L1 BAI1-associated protein 2-like 1
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BCR breakpoint cluster region
BOD1L1 biorientation of chromosomes in cell division 1-like 1
C3 complement component 3
C3ORF33 chromosome 3 open reading frame 33
C9ORF156 chromosome 9 open reading frame 156
CD276 CD276 molecule
CERCAM cerebral endothelial cell adhesion molecule
CLDN4 claudin 4
COL1A1 collagen, type I, alpha 1
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CRYBG3 beta-gamma crystallin domain containing 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CYB561A3 cytochrome b561 family, member A3
DARS aspartyl-tRNA synthetase
DCLRE1B DNA cross-link repair 1B
DIDO1 death inducer-obliterator 1
DNAH11 dynein, axonemal, heavy chain 11
DOLK dolichol kinase
DOPEY2 dopey family member 2
DOT1L DOT1-like histone H3K79 methyltransferase
DRG2 developmentally regulated GTP binding protein 2
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EPHB3 EPH receptor B3
FANCA Fanconi anemia, complementation group A
FKBP10 FK506 binding protein 10, 65 kDa
FMN1 formin 1
FZD1 frizzled class receptor 1
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GTPBP1 GTP binding protein 1
HEATR5A HEAT repeat containing 5A
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HIC2 hypermethylated in cancer 2
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMGXB3 HMG box domain containing 3
HSDL2 hydroxysteroid dehydrogenase like 2
INTS12 integrator complex subunit 12
IQSEC2 IQ motif and Sec7 domain 2
IRS2 insulin receptor substrate 2
ITFG3 integrin alpha FG-GAP repeat containing 3
KIAA1109 KIAA1109
KLF12 Kruppel-like factor 12
KRAS Kirsten rat sarcoma viral oncogene homolog
LARP1B La ribonucleoprotein domain family, member 1B
LEPR leptin receptor
LMTK2 lemur tyrosine kinase 2
LOC81691 exonuclease NEF-sp
LY6E lymphocyte antigen 6 complex, locus E
LYAR Ly1 antibody reactive
MACF1 microtubule-actin crosslinking factor 1
MALT1 MALT1 paracaspase
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAST4 microtubule associated serine/threonine kinase family member 4
MED27 mediator complex subunit 27
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRPS30 mitochondrial ribosomal protein S30
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NAV1 neuron navigator 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFX1 nuclear transcription factor, X-box binding 1
NOP2 NOP2 nucleolar protein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUPL2 nucleoporin like 2
P3H3 prolyl 3-hydroxylase 3
PHF3 PHD finger protein 3
PLEKHA7 pleckstrin homology domain containing, family A member 7
PRSS21 protease, serine, 21 (testisin)
PRSS41 protease, serine, 41
PTPRF protein tyrosine phosphatase, receptor type, F
RAI1 retinoic acid induced 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBL2 retinoblastoma-like 2
RBM15B RNA binding motif protein 15B
REV1 REV1, polymerase (DNA directed)
RREB1 ras responsive element binding protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SETD6 SET domain containing 6
SF3A1 splicing factor 3a, subunit 1, 120kDa
SNPH syntaphilin
SON SON DNA binding protein
SP8 Sp8 transcription factor
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK17B serine/threonine kinase 17b
STRADA STE20-related kinase adaptor alpha
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TMEM2 transmembrane protein 2
TTC37 tetratricopeptide repeat domain 37
TUBE1 tubulin, epsilon 1
UBAP2L ubiquitin associated protein 2-like
UGP2 UDP-glucose pyrophosphorylase 2
ULK1 unc-51 like autophagy activating kinase 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR35 WD repeat domain 35
WRNIP1 Werner helicase interacting protein 1
XDH xanthine dehydrogenase
YEATS2 YEATS domain containing 2
ZBTB11 zinc finger and BTB domain containing 11
ZNF226 zinc finger protein 226
ZNF500 zinc finger protein 500
ZNF574 zinc finger protein 574
ZNF780B zinc finger protein 780B
ZNF800 zinc finger protein 800