LCMT1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description leucine carboxyl methyltransferase 1|LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 51451)
External Link https://ncbi.nlm.nih.gov/gene/51451
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Genes

499 genes differentially expressed following the LCMT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NTS neurotensin 0.0159751
LGALS13 lectin, galactoside-binding, soluble, 13 0.0157078
PRPF4 pre-mRNA processing factor 4 0.0131254
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.0123686
BRCA1 breast cancer 1, early onset 0.0120815
TYRP1 tyrosinase-related protein 1 0.0118576
GREB1 growth regulation by estrogen in breast cancer 1 0.0118215
GNAS GNAS complex locus 0.011613
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0115027
WASHC4 WASH complex subunit 4 0.0113211
CXCL12 chemokine (C-X-C motif) ligand 12 0.0111447
BEX1 brain expressed, X-linked 1 0.0108767
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0108467
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.0105044
SELL selectin L 0.0103532
CD200 CD200 molecule 0.0103274
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0103269
EIF5A eukaryotic translation initiation factor 5A 0.0102979
LAMP5 lysosomal-associated membrane protein family, member 5 0.010195
OLFM4 olfactomedin 4 0.0101837
SNAP25 synaptosomal-associated protein, 25kDa 0.0101295
HBB hemoglobin, beta 0.0099745
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00991715
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00983556
ACP3 acid phosphatase 3 0.00948668
DLK1 delta-like 1 homolog (Drosophila) 0.00943489
DUOX2 dual oxidase 2 0.00940798
NCAPD3 non-SMC condensin II complex, subunit D3 0.00934657
HSDL2 hydroxysteroid dehydrogenase like 2 0.00932467
MAL mal, T-cell differentiation protein 0.00927037
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00921204
LTA4H leukotriene A4 hydrolase 0.00909728
PRKCA protein kinase C, alpha 0.00904692
C7 complement component 7 0.00902921
NUSAP1 nucleolar and spindle associated protein 1 0.00897225
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0089011
ERLIN2 ER lipid raft associated 2 0.00882427
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00878519
NIBAN1 niban apoptosis regulator 1 0.00869864
VSNL1 visinin-like 1 0.00861632
PRUNE2 prune homolog 2 (Drosophila) 0.00854051
PCYOX1L prenylcysteine oxidase 1 like 0.00845134
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0083866
S100A7 S100 calcium binding protein A7 0.00832195
EDNRB endothelin receptor type B 0.00830627
ATP10B ATPase, class V, type 10B 0.00824336
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00810064
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0080516
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00803635
NMU neuromedin U 0.00801434
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00797468
CCK cholecystokinin 0.00796142
COL1A2 collagen, type I, alpha 2 0.0079406
SORD sorbitol dehydrogenase 0.00790788
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00789436
PRKD1 protein kinase D1 0.0078837
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00786867
SPRR3 small proline-rich protein 3 0.00784218
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00781805
ATP5PD ATP synthase peripheral stalk subunit d 0.00779521
GCA grancalcin, EF-hand calcium binding protein 0.00777983
TCEA1 transcription elongation factor A (SII), 1 0.00776363
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00776063
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00769305
CCNG1 cyclin G1 0.00767986
DPYSL3 dihydropyrimidinase-like 3 0.00764681
TMEM38B transmembrane protein 38B 0.00764628
ALCAM activated leukocyte cell adhesion molecule 0.00763389
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00763096
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00762713
GYPC glycophorin C (Gerbich blood group) 0.00761788
CEMIP cell migration inducing protein, hyaluronan binding 0.00761507
C3ORF14 chromosome 3 open reading frame 14 0.00759765
RNF167 ring finger protein 167 0.00758713
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00758056
PUF60 poly-U binding splicing factor 60KDa 0.00746597
LMNB1 lamin B1 0.00745817
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00744608
ESD esterase D 0.00739372
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00736426
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00736103
RPL36 ribosomal protein L36 0.00734256
BCHE butyrylcholinesterase 0.0073391
SERBP1 SERPINE1 mRNA binding protein 1 0.00733668
ZDHHC6 zinc finger, DHHC-type containing 6 0.00730888
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00729757
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00728733
GLO1 glyoxalase I 0.00722395
NSG1 neuron specific gene family member 1 0.00721482
GPR65 G protein-coupled receptor 65 0.00720251
CDC7 cell division cycle 7 0.00718345
LRP4 low density lipoprotein receptor-related protein 4 0.00715431
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00715368
PLLP plasmolipin 0.00714547
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00713166
POPDC3 popeye domain containing 3 0.00712885
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00710592
PI3 peptidase inhibitor 3, skin-derived 0.00708475
PDE4B phosphodiesterase 4B, cAMP-specific 0.00707337
KIF15 kinesin family member 15 0.00702085
HAL histidine ammonia-lyase 0.00701702
MOXD1 monooxygenase, DBH-like 1 0.00701113
KRT1 keratin 1, type II 0.0070067
CADPS2 Ca++-dependent secretion activator 2 0.00699749
OIP5 Opa interacting protein 5 0.0069898
TCEAL2 transcription elongation factor A (SII)-like 2 0.00697971
MEN1 multiple endocrine neoplasia I 0.00695087
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00693891
SIRT3 sirtuin 3 0.00693424
SET SET nuclear proto-oncogene 0.00691657
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00691515
GPM6A glycoprotein M6A 0.00691289
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00689078
PMEL premelanosome protein 0.00687672
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00687544
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00687471
WT1 Wilms tumor 1 0.0068484
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00684807
MSLN mesothelin 0.00684086
PSAT1 phosphoserine aminotransferase 1 0.00683297
SHCBP1 SHC SH2-domain binding protein 1 0.0068273
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00679471
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00679426
TCF21 transcription factor 21 0.00678236
LAPTM4B lysosomal protein transmembrane 4 beta 0.00676827
TARP TCR gamma alternate reading frame protein 0.00676637
FABP7 fatty acid binding protein 7, brain 0.00675416
CPOX coproporphyrinogen oxidase 0.00672993
EIF4B eukaryotic translation initiation factor 4B 0.00670412
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00669873
IFITM2 interferon induced transmembrane protein 2 0.00669081
MEIS2 Meis homeobox 2 0.0066843
KRT2 keratin 2, type II 0.0066567
CCNA2 cyclin A2 0.00662563
PRKCQ protein kinase C, theta 0.00660054
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00659958
SMC2 structural maintenance of chromosomes 2 0.00658515
PLP1 proteolipid protein 1 0.00657838
RPN2 ribophorin II 0.00655599
RGS4 regulator of G-protein signaling 4 0.00654481
AOC1 amine oxidase, copper containing 1 0.00651398
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00649078
CCNF cyclin F 0.00647657
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00644342
ASF1B anti-silencing function 1B histone chaperone 0.00644213
HAUS4 HAUS augmin-like complex, subunit 4 0.00643954
KIAA0226L KIAA0226-like 0.00643161
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00642307
UBE2N ubiquitin-conjugating enzyme E2N 0.00642234
ARG2 arginase 2 0.00641825
IFITM1 interferon induced transmembrane protein 1 0.0063813
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.00636475
EXO1 exonuclease 1 0.00634867
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00634809
IFITM3 interferon induced transmembrane protein 3 0.00632367
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00632331
SALL1 spalt-like transcription factor 1 0.00630152
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.006301
ACTB actin, beta 0.00628626
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00628398
RGS20 regulator of G-protein signaling 20 0.00626782
STXBP6 syntaxin binding protein 6 (amisyn) 0.00623999
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.00622589
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00621902
LIG1 ligase I, DNA, ATP-dependent 0.00621781
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00621633
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00621444
NONO non-POU domain containing, octamer-binding 0.00621301
GUCY2C guanylate cyclase 2C 0.0062126
KRT13 keratin 13, type I 0.00620842
CLDN10 claudin 10 0.00620768
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00617892
LY6D lymphocyte antigen 6 complex, locus D 0.00616656
TYRO3 TYRO3 protein tyrosine kinase 0.00616483
PNMA2 paraneoplastic Ma antigen 2 0.00615574
NPTX2 neuronal pentraxin II 0.00614526
SUB1 SUB1 homolog (S. cerevisiae) 0.00613538
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00613169
FTO fat mass and obesity associated 0.00612297
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00612187
TESC tescalcin 0.006096
DIPK1A divergent protein kinase domain 1A 0.00609367
MAT2B methionine adenosyltransferase II, beta 0.00607947
ADGRE1 adhesion G protein-coupled receptor E1 0.00606545
NLRP2 NLR family, pyrin domain containing 2 0.00606237
STAT4 signal transducer and activator of transcription 4 0.00606047
CIT citron rho-interacting serine/threonine kinase 0.00603213
RNF144A ring finger protein 144A 0.00599508
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00599187
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00599073
AMPH amphiphysin 0.00598967
TOX thymocyte selection-associated high mobility group box 0.00597969
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00597391
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00595984
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00594111
MLANA melan-A 0.00593845
RLN1 relaxin 1 0.00593244
AURKB aurora kinase B 0.00591988
HSPA8 heat shock 70kDa protein 8 0.00591948
OLFML3 olfactomedin-like 3 0.00591556
FANCI Fanconi anemia, complementation group I 0.00591446
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.00591041
RBMX RNA binding motif protein, X-linked 0.00590101
SVIL supervillin 0.00589181
ARHGAP15 Rho GTPase activating protein 15 0.00588429
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00588243
PDIA3 protein disulfide isomerase family A, member 3 0.00586752
CHEK1 checkpoint kinase 1 0.00579926
LAPTM5 lysosomal protein transmembrane 5 0.00578844
H2AX H2A.X variant histone 0.00578537
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00578315
NUP37 nucleoporin 37kDa 0.00577733
DHFR dihydrofolate reductase 0.00575528
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00573538
TSPAN8 tetraspanin 8 0.00573321
RAD54B RAD54 homolog B (S. cerevisiae) 0.0057271
MDFIC MyoD family inhibitor domain containing 0.0057204
BMP7 bone morphogenetic protein 7 0.00569632
SPRR2B small proline-rich protein 2B 0.00568743
SALL2 spalt-like transcription factor 2 0.00566427
CAPN3 calpain 3, (p94) 0.0056588
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00565414
ACE2 angiotensin I converting enzyme 2 0.00564789
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00564103
KIF11 kinesin family member 11 0.00562704
NRGN neurogranin (protein kinase C substrate, RC3) 0.00561975
ADD3 adducin 3 (gamma) 0.0055963
ZBED8 zinc finger, BED-type containing 8 0.00559526
SPDL1 spindle apparatus coiled-coil protein 1 0.00559377
B3GNT1 0.00559226
IFT52 intraflagellar transport 52 0.00557121
RPS25 ribosomal protein S25 0.00556445
PARK7 parkinson protein 7 0.00556159
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00555538
RFC3 replication factor C (activator 1) 3, 38kDa 0.00553639
ATP5F1C ATP synthase F1 subunit gamma 0.00553407
RPL26 ribosomal protein L26 0.00552747
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00551466
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.00550832
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00549524
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.00547828
LCN2 lipocalin 2 0.00547238
IL33R interleukin 33 receptor 0.0054723
ACAD8 acyl-CoA dehydrogenase family, member 8 0.00546409
KIF20A kinesin family member 20A 0.00545694
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00545445
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00544604
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00543686
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00542376
SMAGP small cell adhesion glycoprotein 0.00542346

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0194768
MAP7 microtubule-associated protein 7 -0.0188059
CLU clusterin -0.0169567
CD14 CD14 molecule -0.0163578
MIR22HG MIR22 host gene -0.0147071
SLC38A1 solute carrier family 38, member 1 -0.0139374
RND3 Rho family GTPase 3 -0.0137211
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0137079
PERP PERP, TP53 apoptosis effector -0.0133869
PROM1 prominin 1 -0.0130029
HMOX1 heme oxygenase 1 -0.0129268
WDR7 WD repeat domain 7 -0.0126489
KRT7 keratin 7, type II -0.0126369
CP ceruloplasmin (ferroxidase) -0.0124317
HSPA1A heat shock 70kDa protein 1A -0.0122966
AKAP9 A kinase (PRKA) anchor protein 9 -0.0119043
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0118591
CCN2 cellular communication network factor 2 -0.0117902
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0115656
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0115064
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0114891
PHACTR2 phosphatase and actin regulator 2 -0.0113326
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0112867
NNMT nicotinamide N-methyltransferase -0.0111634
CRYAB crystallin, alpha B -0.0109451
CFH complement factor H -0.0106778
TXLNA taxilin alpha -0.0105932
FTH1 ferritin, heavy polypeptide 1 -0.0104682
CLEC3B C-type lectin domain family 3, member B -0.0102266
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00996575
XIC X chromosome inactivation center -0.00995365
KLF9 Kruppel-like factor 9 -0.0099201
SCGB2A2 secretoglobin, family 2A, member 2 -0.00980048
PMP22 peripheral myelin protein 22 -0.0097524
CCNG2 cyclin G2 -0.00974542
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00974466
STK26 serine/threonine protein kinase 26 -0.00973322
SOD2 superoxide dismutase 2, mitochondrial -0.00961961
FN1 fibronectin 1 -0.00946887
AHR aryl hydrocarbon receptor -0.00942233
TOX3 TOX high mobility group box family member 3 -0.00940634
MYO6 myosin VI -0.00937433
H1-2 H1.2 linker histone, cluster member -0.00934584
CD163 CD163 molecule -0.00933995
COMP cartilage oligomeric matrix protein -0.00933131
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00923719
MMP9 matrix metallopeptidase 9 -0.00923521
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00917344
PLTP phospholipid transfer protein -0.00911937
RGCC regulator of cell cycle -0.00908635
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00907547
PXDC1 PX domain containing 1 -0.00906823
KLF6 Kruppel-like factor 6 -0.00902095
KMT5B lysine methyltransferase 5B -0.00898678
PEG10 paternally expressed 10 -0.00896852
FNDC3B fibronectin type III domain containing 3B -0.0089314
CTSK cathepsin K -0.00891508
SORBS2 sorbin and SH3 domain containing 2 -0.00884368
GREM1 gremlin 1, DAN family BMP antagonist -0.00880551
MGLL monoglyceride lipase -0.00877603
PLPP3 phospholipid phosphatase 3 -0.00876342
HIST1H2BK histone cluster 1, H2bk -0.00870016
LIMCH1 LIM and calponin homology domains 1 -0.00869711
FABP4 fatty acid binding protein 4, adipocyte -0.00865947
CFB complement factor B -0.00858072
C8ORF4 chromosome 8 open reading frame 4 -0.00843959
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00843146
VAMP8 vesicle-associated membrane protein 8 -0.00839967
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.0083642
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00833882
ZNF586 zinc finger protein 586 -0.00831193
DCN decorin -0.00830508
AKR1C2 aldo-keto reductase family 1, member C2 -0.00824167
CCL2 chemokine (C-C motif) ligand 2 -0.00820938
CCL19 chemokine (C-C motif) ligand 19 -0.00819875
TM4SF1 transmembrane 4 L six family member 1 -0.00818989
TENT5A terminal nucleotidyltransferase 5A -0.00814828
KLF5 Kruppel-like factor 5 (intestinal) -0.00813999
DUSP5 dual specificity phosphatase 5 -0.00812137
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00810053
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0080519
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00803587
GRAMD2B GRAM domain containing 2B -0.00800355
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00799291
BMP4 bone morphogenetic protein 4 -0.00798381
TAGLN transgelin -0.00796339
ZNHIT1 zinc finger, HIT-type containing 1 -0.00796215
EMP1 epithelial membrane protein 1 -0.00795793
BRD2 bromodomain containing 2 -0.00789962
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00789525
CCL13 chemokine (C-C motif) ligand 13 -0.00789345
HIST1H2BD histone cluster 1, H2bd -0.00788901
ADIRF adipogenesis regulatory factor -0.00788314
MT1M metallothionein 1M -0.00785093
BAD BCL2-associated agonist of cell death -0.00783247
EHF ets homologous factor -0.00780331
CTSA cathepsin A -0.00779183
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00778878
DCLK1 doublecortin-like kinase 1 -0.00777754
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00774509
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00774453
FOXD1 forkhead box D1 -0.00774333
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00773243
ATF3 activating transcription factor 3 -0.00772407
BIK BCL2-interacting killer (apoptosis-inducing) -0.00769941
SDC2 syndecan 2 -0.00769712
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00769073
NT5E 5'-nucleotidase, ecto (CD73) -0.00767883
TPD52L1 tumor protein D52-like 1 -0.00767852
RRAGC Ras-related GTP binding C -0.00766223
KRT17 keratin 17, type I -0.00766212
TSPAN1 tetraspanin 1 -0.00765148
DOCK9 dedicator of cytokinesis 9 -0.00764731
HIST1H2BH histone cluster 1, H2bh -0.00763723
WASL Wiskott-Aldrich syndrome-like -0.00760621
EFNA1 ephrin-A1 -0.00759362
MGP matrix Gla protein -0.00759079
CEL carboxyl ester lipase -0.00748377
RC3H2 ring finger and CCCH-type domains 2 -0.007482
MMP1 matrix metallopeptidase 1 -0.00747556
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00747316
TGFBI transforming growth factor, beta-induced, 68kDa -0.00744883
SUSD6 sushi domain containing 6 -0.00744502
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0074436
LMNA lamin A/C -0.0074362
STAB1 stabilin 1 -0.00741624
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0074117
SGCE sarcoglycan, epsilon -0.00739647
CCL8 chemokine (C-C motif) ligand 8 -0.00738601
TES testin LIM domain protein -0.00737518
NOTCH2NL notch 2 N-terminal like -0.00735153
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00735136
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00730827
GBP2 guanylate binding protein 2, interferon-inducible -0.00730427
AKR1C1 aldo-keto reductase family 1, member C1 -0.00725574
SOX4 SRY (sex determining region Y)-box 4 -0.00724802
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00724384
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00724036
AK1 adenylate kinase 1 -0.00721448
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00719346
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00719185
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00714744
AMOTL2 angiomotin like 2 -0.00714031
RHOD ras homolog family member D -0.00713636
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00713627
SCGB2A1 secretoglobin, family 2A, member 1 -0.00712352
AMDHD2 amidohydrolase domain containing 2 -0.0071194
MVP major vault protein -0.00709352
DYNLL1 dynein, light chain, LC8-type 1 -0.00701019
SERINC1 serine incorporator 1 -0.00700418
AHNAK AHNAK nucleoprotein -0.00697244
KRT23 keratin 23, type I -0.00695588
KCTD12 potassium channel tetramerization domain containing 12 -0.00695326
STEAP3 STEAP family member 3, metalloreductase -0.0069451
TSPAN13 tetraspanin 13 -0.00692534
SNAI2 snail family zinc finger 2 -0.00691234
INSM1 insulinoma-associated 1 -0.00687697
SETD5 SET domain containing 5 -0.00685996
CRIP1 cysteine-rich protein 1 (intestinal) -0.00680388
SIK1 salt-inducible kinase 1 -0.00679356
NBPF10 neuroblastoma breakpoint family, member 10 -0.00679093
MT1X metallothionein 1X -0.00678947
TSC22D1 TSC22 domain family, member 1 -0.0067785
KLF4 Kruppel-like factor 4 (gut) -0.00676805
TFPI2 tissue factor pathway inhibitor 2 -0.00676168
ZNF83 zinc finger protein 83 -0.00676041
FHL2 four and a half LIM domains 2 -0.00675352
NVL nuclear VCP-like -0.00673743
PLK2 polo-like kinase 2 -0.00671834
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00671577
SOWAHC sosondowah ankyrin repeat domain family member C -0.00668655
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -0.00668213
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00668185
PRSS23 protease, serine, 23 -0.00662891
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00661509
TXNRD1 thioredoxin reductase 1 -0.00661221
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00660168
ASS1 argininosuccinate synthase 1 -0.00660104
RAB9A RAB9A, member RAS oncogene family -0.00659432
CA12 carbonic anhydrase XII -0.00657235
PDE4DIP phosphodiesterase 4D interacting protein -0.00656972
LTBP2 latent transforming growth factor beta binding protein 2 -0.00656953
EMP3 epithelial membrane protein 3 -0.00655543
S100A8 S100 calcium binding protein A8 -0.0065364
S100A2 S100 calcium binding protein A2 -0.00653064
ANKRD28 ankyrin repeat domain 28 -0.00652589
DSP desmoplakin -0.00651959
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00650933
FSCN1 fascin actin-bundling protein 1 -0.00649389
VSIG4 V-set and immunoglobulin domain containing 4 -0.00649347
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00647455
MRPS30 mitochondrial ribosomal protein S30 -0.00645175
SCRG1 stimulator of chondrogenesis 1 -0.0064474
YBX3 Y box binding protein 3 -0.00644298
RIN2 Ras and Rab interactor 2 -0.00641473
TMEM47 transmembrane protein 47 -0.00640534
GPX3 glutathione peroxidase 3 -0.00639593
ANKRD12 ankyrin repeat domain 12 -0.00639534
CD34 CD34 molecule -0.0063703
ING3 inhibitor of growth family, member 3 -0.00634805
KLC1 kinesin light chain 1 -0.00633912
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00633762
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00632532
LRRC1 leucine rich repeat containing 1 -0.00631133
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00630856
ADAMDEC1 ADAM-like, decysin 1 -0.00630099
MX1 MX dynamin-like GTPase 1 -0.00629452
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00629233
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00628367
OSR2 odd-skipped related transciption factor 2 -0.0062728
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00626926
LAMB2 laminin, beta 2 (laminin S) -0.00625408
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.00621632
SCGB1D2 secretoglobin, family 1D, member 2 -0.00621157
OBSL1 obscurin-like 1 -0.0062077
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00619385
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00619158
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00618268
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.0061748
MCL1 myeloid cell leukemia 1 -0.00617124
SQSTM1 sequestosome 1 -0.00616995
ARHGAP29 Rho GTPase activating protein 29 -0.00615871
TPSAB1 tryptase alpha/beta 1 -0.00613945
PLAAT3 phospholipase A and acyltransferase 3 -0.00611574
C1R complement component 1, r subcomponent -0.00611092
AKAP8 A kinase (PRKA) anchor protein 8 -0.00610369
BAG1 BCL2-associated athanogene -0.0061031
SLC38A6 solute carrier family 38, member 6 -0.0061027
TGM2 transglutaminase 2 -0.00607974
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00607303
ACKR3 atypical chemokine receptor 3 -0.00605823
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -0.00605818
SENP6 SUMO1/sentrin specific peptidase 6 -0.00605572
TNS3 tensin 3 -0.00605443
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00604655
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00604022
PPL periplakin -0.00603551
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -0.00602612
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00600782
HIST1H2AE histone cluster 1, H2ae -0.00600464
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00600395
ZNF91 zinc finger protein 91 -0.00600388
MFAP5 microfibrillar associated protein 5 -0.00599603
BTG1 B-cell translocation gene 1, anti-proliferative -0.00596359
EVA1B eva-1 homolog B (C. elegans) -0.00595144
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00592253
SETBP1 SET binding protein 1 -0.00591643
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00591394
SGK1 serum/glucocorticoid regulated kinase 1 -0.00591234