LETROZOLE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A triazole that has formula C17H11N5. (Chemical Entities of Biological Interest Ontology, CHEBI_6413)
External Link https://dgidb.org/results?searchType=drug&searchTerms=LETROZOLE
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Genes

17 interacting proteins for the LETROZOLE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CCDC148 coiled-coil domain containing 148 3.11365
ZNF613 zinc finger protein 613 2.07576
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.08978
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.879944
SFTPA1 surfactant protein A1 0.389206
CDKN2A cyclin-dependent kinase inhibitor 2A 0.214734
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.168305
RB1 retinoblastoma 1 0.155682
MMP2 matrix metallopeptidase 2 0.129735
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0864902
PGR progesterone receptor 0.0819381
ESR1 estrogen receptor 1 0.0627751
ERBB2 erb-b2 receptor tyrosine kinase 2 0.0483987
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.0464723
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0441652
PTEN phosphatase and tensin homolog 0.040437
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00351427