LHX3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description LIM homeobox 3|This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene cause combined pituitary hormone deficiency 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 8022)
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Genes

362 genes differentially expressed following the LHX3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.96605
DNASE1L2 deoxyribonuclease I-like 2 2.96605
TM4SF5 transmembrane 4 L six family member 5 2.96605
GRXCR2 glutaredoxin, cysteine rich 2 2.96605
CXORF65 chromosome X open reading frame 65 2.96605
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 2.96605
LRG1 leucine-rich alpha-2-glycoprotein 1 2.96605
RSPO3 R-spondin 3 2.96605
TAL2 T-cell acute lymphocytic leukemia 2 2.96605
LYZL6 lysozyme-like 6 2.96605
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.96605
FGL2 fibrinogen-like 2 2.96605
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.96605
RNF17 ring finger protein 17 2.96605
FGF21 fibroblast growth factor 21 2.96605
FGD2 FYVE, RhoGEF and PH domain containing 2 2.96605
FAM180B family with sequence similarity 180, member B 2.96605
CTRC chymotrypsin C (caldecrin) 2.96605
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.96605
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.96605
OR4F17 olfactory receptor, family 4, subfamily F, member 17 2.96605
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.96605
TMEM176B transmembrane protein 176B 2.96605
ANKRD34A ankyrin repeat domain 34A 2.96605
LRRC10B leucine rich repeat containing 10B 2.96605
KRTAP5-5 keratin associated protein 5-5 2.96605
TECTB tectorin beta 2.96605
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.96605
LEP leptin 2.96605
CCDC82 coiled-coil domain containing 82 2.96605
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.96605
HRG histidine-rich glycoprotein 2.96605
TPH1 tryptophan hydroxylase 1 2.96605
SPDEF SAM pointed domain containing ETS transcription factor 2.96605
CD22 CD22 molecule 2.96605
PRDM1 PR domain containing 1, with ZNF domain 2.96605
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.96605
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.96605
LGI3 leucine-rich repeat LGI family, member 3 2.96605
MISP mitotic spindle positioning 2.96605
MUC20 mucin 20, cell surface associated 2.96605
CAPS calcyphosine 2.96605
BMP5 bone morphogenetic protein 5 2.96605
MRC1 mannose receptor, C type 1 2.96605
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.96605
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.96605
SP6 Sp6 transcription factor 2.96605
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.96605
COXFA4L3 cytochrome c oxidase associated subunit FA4L3 2.96605
DERPC DERPC proline and glycine rich nuclear protein 2.96605
H1-6 H1.6 linker histone, cluster member 2.96605
SPATS1 spermatogenesis associated, serine-rich 1 2.96605
ARX aristaless related homeobox 2.96605
CLDN14 claudin 14 2.96605
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.96605
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.96605
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.96605
MYEOV myeloma overexpressed 2.96605
WNT16 wingless-type MMTV integration site family, member 16 2.96605
DIPK1C divergent protein kinase domain 1C 2.96605
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.96605
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.96605
PNMA6F PNMA family member 6F 2.96605
C8ORF90 chromosome 8 open reading frame 90 2.96605
CIMIP3 ciliary microtubule inner protein 3 2.96605
LOC124906010 uncharacterized LOC124906010 2.96605
H3C13 H3 clustered histone 13 2.96605
CTXND1 cortexin domain containing 1 2.96605
ARMH2 armadillo like helical domain containing 2 2.96605
MEIOSIN meiosis initiator 2.96605
DEFB131B defensin beta 131B 2.96605
GATA6 GATA binding protein 6 2.96605
PRDM7 PR domain containing 7 2.96605
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.96605
GZMM granzyme M (lymphocyte met-ase 1) 2.96605
NPIPB9 nuclear pore complex interacting protein family, member B9 2.96605
TMCO2 transmembrane and coiled-coil domains 2 2.96605
EDAR ectodysplasin A receptor 2.96605
RAB44 RAB44, member RAS oncogene family 2.96605
ZNF436 zinc finger protein 436 2.96605
RS1 retinoschisin 1 2.96605
CPNE6 copine VI (neuronal) 2.96605
HBA2 hemoglobin, alpha 2 2.96605
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.96605
SPDYE16 speedy/RINGO cell cycle regulator family member E16 2.96605
RNF183 ring finger protein 183 2.96605
CCDC42 coiled-coil domain containing 42 2.96605
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.96605
PCDHGC4 protocadherin gamma subfamily C, 4 2.96605
NPIPB8 nuclear pore complex interacting protein family, member B8 2.96605
LRRC72 leucine rich repeat containing 72 2.96605
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.96605
DDTL D-dopachrome tautomerase-like 2.96605
CELA2A chymotrypsin-like elastase family, member 2A 2.96605
PRR4 proline rich 4 (lacrimal) 2.96605
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.96605
VWC2L von Willebrand factor C domain containing protein 2-like 2.96605
DUOX1 dual oxidase 1 2.96605
EPGN epithelial mitogen 2.96605
KLK6 kallikrein-related peptidase 6 2.96605
SLCO2B1 solute carrier organic anion transporter family, member 2B1 2.96605
IL9R interleukin 9 receptor 2.96605
AICDA activation-induced cytidine deaminase 2.96605
ITGA8 integrin, alpha 8 2.96605
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.96605
DLX5 distal-less homeobox 5 2.96605
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.96605
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 2.96605
TBPL2 TATA box binding protein like 2 2.96605
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.96605
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 2.96605
SMYD1 SET and MYND domain containing 1 2.96605
SLC22A24 solute carrier family 22, member 24 2.96605
CHI3L2 chitinase 3-like 2 2.96605
KLF1 Kruppel-like factor 1 (erythroid) 2.96605
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.96605
FAM177B family with sequence similarity 177, member B 2.96605
VNN1 vanin 1 2.96605
ARR3 arrestin 3, retinal (X-arrestin) 2.96605
CERKL ceramide kinase-like 2.96605
APOC4 apolipoprotein C-IV 2.96605
AMIGO1 adhesion molecule with Ig-like domain 1 2.96605
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.96605
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 2.96605
CGB1 chorionic gonadotropin, beta polypeptide 1 2.96605
VWA7 von Willebrand factor A domain containing 7 2.96605
CLEC18C C-type lectin domain family 18, member C 2.96605
TEX19 testis expressed 19 2.96605
TMPPE transmembrane protein with metallophosphoesterase domain 2.96605
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.96605
GH1 growth hormone 1 2.96605
C10ORF105 chromosome 10 open reading frame 105 2.96605
DEFB134 defensin, beta 134 2.96605
OR56B1 olfactory receptor, family 56, subfamily B, member 1 2.96605
COL22A1 collagen, type XXII, alpha 1 2.96605
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 2.96605
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.96605
FOXP3 forkhead box P3 2.96605
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.96605
ALLC allantoicase 2.96605
SEZ6L seizure related 6 homolog (mouse)-like 2.96605
CFI complement factor I 2.96605
ANGPTL7 angiopoietin-like 7 2.96605
PHOX2A paired-like homeobox 2a 2.96605
TMEM88 transmembrane protein 88 2.96605
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.96605
SP100 SP100 nuclear antigen 2.96605
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.96605
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.96605
TSPAN19 tetraspanin 19 2.96605
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 2.96605
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.96605
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.96605
ZMYND10 zinc finger, MYND-type containing 10 2.96605
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 2.96605
SLFN12L schlafen family member 12-like 2.96605
NUTM2G NUT family member 2G 2.96605
PRR15L proline rich 15-like 2.96605
MAEL maelstrom spermatogenic transposon silencer 2.96605
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.96605
CEP63 centrosomal protein 63kDa 2.8931
SLC25A51 solute carrier family 25, member 51 2.89184
MBNL1 muscleblind-like splicing regulator 1 2.89184
TUFM Tu translation elongation factor, mitochondrial 2.80008
SLC16A9 solute carrier family 16, member 9 2.79954
UBE2E1 ubiquitin-conjugating enzyme E2E 1 2.78474
SPDYE2 speedy/RINGO cell cycle regulator family member E2 2.72601
RFT1 RFT1 homolog (S. cerevisiae) 2.6333
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 2.6167
OVGP1 oviductal glycoprotein 1, 120kDa 2.60178
CCDC178 coiled-coil domain containing 178 2.58714
CCNG2 cyclin G2 2.55533
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 2.54346
C6ORF120 chromosome 6 open reading frame 120 2.51416
EPHA3 EPH receptor A3 2.50778
SCART1 scavenger receptor protein family member 2.50778
ZNF791 zinc finger protein 791 2.47935
FOXP2 forkhead box P2 2.45755
AXIN1 axin 1 2.44079
TOX4 TOX high mobility group box family member 4 2.40709
BAD BCL2-associated agonist of cell death 2.39249
MFGE8 milk fat globule-EGF factor 8 protein 2.39249
ELMOD3 ELMO/CED-12 domain containing 3 2.38353
ARHGAP35 Rho GTPase activating protein 35 2.30218
FAM227A family with sequence similarity 227, member A 2.28414
CTSZ cathepsin Z 2.28379
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.28379
TNNI1 troponin I type 1 (skeletal, slow) 2.28379
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.28379
CD2AP CD2-associated protein 2.27354
CCDC77 coiled-coil domain containing 77 2.24967
ATG5 autophagy related 5 2.23922
DIPK1B divergent protein kinase domain 1B 2.23497
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.2224
ATG12 autophagy related 12 2.21532
CCL26 chemokine (C-C motif) ligand 26 2.21413
CRIPT cysteine-rich PDZ-binding protein 2.20741
BCLAF1 BCL2-associated transcription factor 1 2.20105
H3C2 H3 clustered histone 2 2.19744
RPS25 ribosomal protein S25 2.17023
DUSP22 dual specificity phosphatase 22 2.14787
LIMS1 LIM and senescent cell antigen-like domains 1 2.1149
SYF2 SYF2 pre-mRNA-splicing factor 2.11248
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 2.11078
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 2.1092
FXR1 fragile X mental retardation, autosomal homolog 1 2.10811
ARPP19 cAMP-regulated phosphoprotein, 19kDa 2.10338
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2.09031
GANC glucosidase, alpha; neutral C 2.08982
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 2.08286
RGS11 regulator of G-protein signaling 11 2.08286
ACP4 acid phosphatase 4 2.08286
PRB3 proline-rich protein BstNI subfamily 3 2.08286
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.08286
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.08286
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.08286
NPIPB15 nuclear pore complex interacting protein family, member B15 2.08286
TNMD tenomodulin 2.04078
ZBTB38 zinc finger and BTB domain containing 38 2.04046
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.03625
TES testin LIM domain protein 2.03625
SLCO4C1 solute carrier organic anion transporter family, member 4C1 2.03225
C12ORF60 chromosome 12 open reading frame 60 2.02667
ANAPC16 anaphase promoting complex subunit 16 2.02665
PFDN6 prefoldin subunit 6 2.02633
DAZL deleted in azoospermia-like 2.02633
PRMT3 protein arginine methyltransferase 3 2.02565
BCAP31 B-cell receptor-associated protein 31 2.02178
TRIM6 tripartite motif containing 6 2.02178
SRD5A3 steroid 5 alpha-reductase 3 2.02014
ACOX3 acyl-CoA oxidase 3, pristanoyl 2.01202
MTFR1 mitochondrial fission regulator 1 2.01202
LONP1 lon peptidase 1, mitochondrial 2.00663
UBE2E3 ubiquitin-conjugating enzyme E2E 3 2.00549
CRAMP1 cramped chromatin regulator homolog 1 2.00549
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.00317
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 2.00259

decreased expression

Symbol Name Standardized Value
RWDD2A RWD domain containing 2A -2.96605
RNF14 ring finger protein 14 -2.96605
ACTB actin, beta -2.96605
ZAN zonadhesin (gene/pseudogene) -2.96605
GFRA3 GDNF family receptor alpha 3 -2.96605
LYPD1 LY6/PLAUR domain containing 1 -2.96605
TUB tubby bipartite transcription factor -2.96605
SPMIP3 sperm microtubule inner protein 3 -2.96605
USH1G Usher syndrome 1G (autosomal recessive) -2.89184
EDN3 endothelin 3 -2.89184
PCDHB13 protocadherin beta 13 -2.89184
ADAM8 ADAM metallopeptidase domain 8 -2.89184
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -2.89184
C6ORF163 chromosome 6 open reading frame 163 -2.89184
CRYBB2 crystallin, beta B2 -2.89184
APOB apolipoprotein B -2.89184
CPZ carboxypeptidase Z -2.89184
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) -2.89184
ATOH1 atonal homolog 1 (Drosophila) -2.89184
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.89184
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.89184
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -2.89184
PPP1R3C protein phosphatase 1, regulatory subunit 3C -2.89184
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -2.89184
FBLN7 fibulin 7 -2.89184
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.89184
CDH10 cadherin 10, type 2 (T2-cadherin) -2.89184
TUBA3D tubulin, alpha 3d -2.89184
IRF4 interferon regulatory factor 4 -2.89184
MYL7 myosin, light chain 7, regulatory -2.89184
LINC02798 long intergenic non-protein coding RNA 2798 -2.89184
GATA3 GATA binding protein 3 -2.89184
MUSTN1 musculoskeletal, embryonic nuclear protein 1 -2.89184
INSM1 insulinoma-associated 1 -2.89184
SCN4B sodium channel, voltage gated, type IV beta subunit -2.89184
QRFP pyroglutamylated RFamide peptide -2.89184
NOTCH4 notch 4 -2.89184
LOC124902436 talanin -2.89184
HLA-DMB major histocompatibility complex, class II, DM beta -2.89184
MAML2 mastermind-like 2 (Drosophila) -2.89184
RAD21L1 RAD21-like 1 (S. pombe) -2.89184
LEF1 lymphoid enhancer-binding factor 1 -2.89184
RABL6 RAB, member RAS oncogene family-like 6 -2.77019
PTH2R parathyroid hormone 2 receptor -2.76422
EPSTI1 epithelial stromal interaction 1 (breast) -2.76422
NXNL2 nucleoredoxin-like 2 -2.73162
FBXO2 F-box protein 2 -2.72541
CCK cholecystokinin -2.67675
ZNF28 zinc finger protein 28 -2.62459
C12ORF56 chromosome 12 open reading frame 56 -2.59106
TMEM61 transmembrane protein 61 -2.59082
SUGP2 SURP and G patch domain containing 2 -2.55533
ZNF17 zinc finger protein 17 -2.54346
STRN4 striatin, calmodulin binding protein 4 -2.52383
N4BP3 NEDD4 binding protein 3 -2.52228
PCDHB14 protocadherin beta 14 -2.47935
SFRP5 secreted frizzled-related protein 5 -2.47935
NOL10 nucleolar protein 10 -2.45567
LSM12 LSM12 homolog (S. cerevisiae) -2.45473
RB1CC1 RB1-inducible coiled-coil 1 -2.45127
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -2.43903
MACF1 microtubule-actin crosslinking factor 1 -2.43317
SPATS2L spermatogenesis associated, serine-rich 2-like -2.40709
RADIL Ras association and DIL domains -2.40709
ZNF85 zinc finger protein 85 -2.37359
PRELID3A PRELI domain containing 3A -2.36282
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.32914
FBP1 fructose-1,6-bisphosphatase 1 -2.32914
PNRC1 proline-rich nuclear receptor coactivator 1 -2.31331
AKAP13 A kinase (PRKA) anchor protein 13 -2.30745
LRRC20 leucine rich repeat containing 20 -2.28756
CHD9NB CHD9 neighbor -2.28414
WDR11 WD repeat domain 11 -2.28379
ORC4 origin recognition complex, subunit 4 -2.28379
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.28379
RTL8C retrotransposon Gag like 8C -2.28379
ERVH48-1 endogenous retrovirus group 48, member 1 -2.28379
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta -2.2814
TMEM151A transmembrane protein 151A -2.27801
NPIPA5 nuclear pore complex interacting protein family, member A5 -2.27801
USP49 ubiquitin specific peptidase 49 -2.26436
DIAPH1 diaphanous-related formin 1 -2.24729
STK38 serine/threonine kinase 38 -2.24729
ZBTB37 zinc finger and BTB domain containing 37 -2.23119
ABI3BP ABI family, member 3 (NESH) binding protein -2.22993
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 -2.2281
UNC5A unc-5 homolog A (C. elegans) -2.2224
FANCM Fanconi anemia, complementation group M -2.2015
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.20049
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -2.19298
PPP1R3F protein phosphatase 1, regulatory subunit 3F -2.18549
KAT7 K(lysine) acetyltransferase 7 -2.18549
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.18486
FGF20 fibroblast growth factor 20 -2.17854
IL18 interleukin 18 -2.17854
TBCD tubulin folding cofactor D -2.17041
EML1 echinoderm microtubule associated protein like 1 -2.16963
NKAIN1 Na+/K+ transporting ATPase interacting 1 -2.16227
ZNF730 zinc finger protein 730 -2.1593
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.1593
BEND3 BEN domain containing 3 -2.14787
FCHO1 FCH domain only 1 -2.13403
KIRREL2 kin of IRRE like 2 (Drosophila) -2.11724
ABHD13 abhydrolase domain containing 13 -2.11724
SLC43A3 solute carrier family 43, member 3 -2.11248
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.11248
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.11078
TMEM121B transmembrane protein 121B -2.11078
RASL11B RAS-like, family 11, member B -2.08813
GAR1 GAR1 ribonucleoprotein -2.08456
PCDHGA5 protocadherin gamma subfamily A, 5 -2.08286
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.08286
STK10 serine/threonine kinase 10 -2.08286
PEF1 penta-EF-hand domain containing 1 -2.07818
NOP2 NOP2 nucleolar protein -2.06828
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.04078
UBAP2L ubiquitin associated protein 2-like -2.03927
MUTYH mutY homolog -2.02178
WFDC10B WAP four-disulfide core domain 10B -2.02178
NUMBL numb homolog (Drosophila)-like -2.02178
GRB2 growth factor receptor-bound protein 2 -2.02178
ESPN espin -2.02178
WBP1 WW domain binding protein 1 -2.02178
ARL2 ADP-ribosylation factor-like 2 -2.02178
ZNF486 zinc finger protein 486 -2.00317