LIVF001-016 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

533 genes differentially expressed following the LIVF001-016 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FSD1 fibronectin type III and SPRY domain containing 1 9.78839
NOTCH1 notch 1 9.41452
LYN LYN proto-oncogene, Src family tyrosine kinase 9.17814
MNAT1 MNAT CDK-activating kinase assembly factor 1 8.00281
TCTN1 tectonic family member 1 7.77381
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 7.35859
EFHC2 EF-hand domain (C-terminal) containing 2 5.97801
IQGAP2 IQ motif containing GTPase activating protein 2 5.91466
DOK4 docking protein 4 5.57235
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 5.52643
CD160 CD160 molecule 5.46117
SLF2 SMC5-SMC6 complex localization factor 2 5.35374
NPAS3 neuronal PAS domain protein 3 5.30432
SQOR sulfide quinone oxidoreductase 5.29055
MAST2 microtubule associated serine/threonine kinase 2 5.03836
TRPV1 transient receptor potential cation channel, subfamily V, member 1 4.99638
NUSAP1 nucleolar and spindle associated protein 1 4.99368
TGS1 trimethylguanosine synthase 1 4.94669
EDN3 endothelin 3 4.92218
RAB22A RAB22A, member RAS oncogene family 4.87487
MCM4 minichromosome maintenance complex component 4 4.83687
TOX thymocyte selection-associated high mobility group box 4.80451
NTS neurotensin 4.77881
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 4.76059
HAPLN1 hyaluronan and proteoglycan link protein 1 4.62271
ELOVL5 ELOVL fatty acid elongase 5 4.61312
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 4.58979
MCM6 minichromosome maintenance complex component 6 4.55197
BTN1A1 butyrophilin, subfamily 1, member A1 4.51384
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 4.49738
CNTNAP1 contactin associated protein 1 4.49335
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 4.48665
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 4.44674
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 4.43434
PCNA proliferating cell nuclear antigen 4.41843
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 4.36729
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 4.34722
SMAD7 SMAD family member 7 4.3458
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 4.33947
CHP1 calcineurin-like EF-hand protein 1 4.33226
IL2RB interleukin 2 receptor, beta 4.32224
LDB1 LIM domain binding 1 4.32222
SIM1 single-minded family bHLH transcription factor 1 4.31915
PTPN3 protein tyrosine phosphatase, non-receptor type 3 4.31532
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 4.3036
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 4.29599
PZP pregnancy-zone protein 4.28859
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 4.22558
TSPAN5 tetraspanin 5 4.21386
COLEC11 collectin sub-family member 11 4.18996
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 4.16734
NELL1 NEL-like 1 (chicken) 4.16126
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 4.15985
GOSR2 golgi SNAP receptor complex member 2 4.15139
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 4.14053
EYA2 EYA transcriptional coactivator and phosphatase 2 4.12828
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 4.09651
PRSS3 protease, serine, 3 4.08965
GBX1 gastrulation brain homeobox 1 4.07876
KLRD1 killer cell lectin-like receptor subfamily D, member 1 4.07221
TYMS thymidylate synthetase 4.07102
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 4.06937
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 4.06673
STXBP6 syntaxin binding protein 6 (amisyn) 4.06282
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 4.04852
MMP26 matrix metallopeptidase 26 4.02952
SPP1 secreted phosphoprotein 1 4.02876
ACSL5 acyl-CoA synthetase long-chain family member 5 4.01943
RGS4 regulator of G-protein signaling 4 4.0135
MCTP2 multiple C2 domains, transmembrane 2 4.01257
HAT1 histone acetyltransferase 1 4.00886
HELLS helicase, lymphoid-specific 3.9994
IFNG interferon, gamma 3.98953
HSPA12A heat shock 70kDa protein 12A 3.98922
PRPH2 peripherin 2 (retinal degeneration, slow) 3.9874
HOXB7 homeobox B7 3.98222
FOXA2 forkhead box A2 3.97189
PTGDR prostaglandin D2 receptor (DP) 3.96509
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 3.92705
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 3.91518
LAPTM4B lysosomal protein transmembrane 4 beta 3.89531
EDDM3A epididymal protein 3A 3.87772
RIMBP2 RIMS binding protein 2 3.87721
SLIT1 slit homolog 1 (Drosophila) 3.87637
CD8B CD8b molecule 3.86964
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 3.8695
MRPL49 mitochondrial ribosomal protein L49 3.8664
OVGP1 oviductal glycoprotein 1, 120kDa 3.82855
KLRK1 killer cell lectin-like receptor subfamily K, member 1 3.82122
LRRC17 leucine rich repeat containing 17 3.80568
CEP192 centrosomal protein 192kDa 3.79099
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 3.77502
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 3.7605
BDNF brain-derived neurotrophic factor 3.7159
PLBD1 phospholipase B domain containing 1 3.71065
EGFL7 EGF-like-domain, multiple 7 3.70802
PGAM1 phosphoglycerate mutase 1 (brain) 3.70613
MEOX2 mesenchyme homeobox 2 3.68606
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 3.68109
EFR3A EFR3 homolog A (S. cerevisiae) 3.67741
FAIM2 Fas apoptotic inhibitory molecule 2 3.67309
BICC1 BicC family RNA binding protein 1 3.66261
PDZD8 PDZ domain containing 8 3.6613
GCC2 GRIP and coiled-coil domain containing 2 3.66022
THSD4 thrombospondin, type I, domain containing 4 3.65015
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 3.64001
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 3.63702
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 3.62813
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 3.6228
SESN1 sestrin 1 3.62176
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.62059
CCL20 chemokine (C-C motif) ligand 20 3.6177
EPS15 epidermal growth factor receptor pathway substrate 15 3.6171
APOE apolipoprotein E 3.60401
MME membrane metallo-endopeptidase 3.60037
PRIM1 primase, DNA, polypeptide 1 (49kDa) 3.60006
CPM carboxypeptidase M 3.59235
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 3.59063
UXS1 UDP-glucuronate decarboxylase 1 3.57678
ZBBX zinc finger, B-box domain containing 3.57505
TRIM10 tripartite motif containing 10 3.57423
TSNAXIP1 translin-associated factor X interacting protein 1 3.57137
RAB33A RAB33A, member RAS oncogene family 3.54866
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 3.54725
DNAI4 dynein axonemal intermediate chain 4 3.54473
SPINT3 serine peptidase inhibitor, Kunitz type, 3 3.54348
DNAI7 dynein axonemal intermediate chain 7 3.54186
ERGIC2 ERGIC and golgi 2 3.54128
GINS1 GINS complex subunit 1 (Psf1 homolog) 3.52989
ATP9A ATPase, class II, type 9A 3.52967
STRA6 stimulated by retinoic acid 6 3.52223
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 3.51251
CPED1 cadherin-like and PC-esterase domain containing 1 3.50298
LPAR1 lysophosphatidic acid receptor 1 3.50132
CCL4 chemokine (C-C motif) ligand 4 3.50079
LRRC20 leucine rich repeat containing 20 3.50062
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 3.49998
NSFL1C NSFL1 (p97) cofactor (p47) 3.49801
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.49755
HOXB5 homeobox B5 3.49085
RBM7 RNA binding motif protein 7 3.47315
BCL2A1 BCL2-related protein A1 3.47149
GPR52 G protein-coupled receptor 52 3.46963
SHOX short stature homeobox 3.45768
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 3.45761
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 3.45572
COL11A2 collagen, type XI, alpha 2 3.45518
TM9SF3 transmembrane 9 superfamily member 3 3.45306
A1CF APOBEC1 complementation factor 3.45246
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 3.45097
DNAI2 dynein, axonemal, intermediate chain 2 3.44486
CRISP1 cysteine-rich secretory protein 1 3.44125
RBBP7 retinoblastoma binding protein 7 3.437
SPAG11B sperm associated antigen 11B 3.43682
FEN1 flap structure-specific endonuclease 1 3.43443
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.43404
GJB1 gap junction protein, beta 1, 32kDa 3.42646
ITM2B integral membrane protein 2B 3.41943
FUT2 fucosyltransferase 2 (secretor status included) 3.40749
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 3.40256
IDS iduronate 2-sulfatase 3.40018
EXT2 exostosin glycosyltransferase 2 3.39877
NR2E1 nuclear receptor subfamily 2, group E, member 1 3.38939
COL21A1 collagen, type XXI, alpha 1 3.38918
PRKCQ protein kinase C, theta 3.38375
S100A11 S100 calcium binding protein A11 3.38218
RPL13P5 ribosomal protein L13 pseudogene 5 3.38098
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 3.34916
RGS1 regulator of G-protein signaling 1 3.34762
NALF1 NALCN channel auxiliary factor 1 3.3327
ENC1 ectodermal-neural cortex 1 (with BTB domain) 3.32552
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 3.32549
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 3.31597
SLC26A2 solute carrier family 26 (anion exchanger), member 2 3.31552
SNAP23 synaptosomal-associated protein, 23kDa 3.31544
NASP nuclear autoantigenic sperm protein (histone-binding) 3.31375
GATA2 GATA binding protein 2 3.31317
BTNL3 butyrophilin-like 3 3.30318
ANPEP alanyl (membrane) aminopeptidase 3.29882
IL33R interleukin 33 receptor 3.29781
HOXA10 homeobox A10 3.29241
BAALC brain and acute leukemia, cytoplasmic 3.29206
PDZD7 PDZ domain containing 7 3.29032
BBOF1 basal body orientation factor 1 3.29015
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 3.28958
ARHGAP26 Rho GTPase activating protein 26 3.28367
SYNGR1 synaptogyrin 1 3.28107
ASCL3 achaete-scute family bHLH transcription factor 3 3.27508
ADAMDEC1 ADAM-like, decysin 1 3.27276
MAK16 MAK16 homolog (S. cerevisiae) 3.27166
SPDEF SAM pointed domain containing ETS transcription factor 3.25428
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.2487
CLDN10 claudin 10 3.23165
TWIST1 twist family bHLH transcription factor 1 3.22869
QPRT quinolinate phosphoribosyltransferase 3.22607
KLK14 kallikrein-related peptidase 14 3.22584
DLG1 discs, large homolog 1 (Drosophila) 3.20813
OVOL2 ovo-like zinc finger 2 3.20788
PDIA2 protein disulfide isomerase family A, member 2 3.20176
MEG3 maternally expressed 3 (non-protein coding) 3.19621
WRN Werner syndrome, RecQ helicase-like 3.19291
GLB1 galactosidase, beta 1 3.18814
NCR2 natural cytotoxicity triggering receptor 2 3.17189
FAM163A family with sequence similarity 163, member A 3.16724
COPZ2 coatomer protein complex, subunit zeta 2 3.16347
ZNF423 zinc finger protein 423 3.16212
DRD5 dopamine receptor D5 3.1618
FLRT1 fibronectin leucine rich transmembrane protein 1 3.15866
CD83 CD83 molecule 3.15814
POGLUT2 protein O-glucosyltransferase 2 3.1562
RBKS ribokinase 3.15518
ZWINT ZW10 interacting kinetochore protein 3.15313
HPF1 histone PARylation factor 1 3.15282
AMOT angiomotin 3.15272
CD320 CD320 molecule 3.15271
TUBG1 tubulin, gamma 1 3.14911
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 3.14773
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 3.14708
GINS2 GINS complex subunit 2 (Psf2 homolog) 3.14492
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 3.1375
BTBD1 BTB (POZ) domain containing 1 3.13017
CNR2 cannabinoid receptor 2 (macrophage) 3.12849
SYN3 synapsin III 3.12388
PXMP4 peroxisomal membrane protein 4, 24kDa 3.12226
DHFR dihydrofolate reductase 3.11641
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 3.1135
SCGB2A1 secretoglobin, family 2A, member 1 3.10505
LIMS1 LIM and senescent cell antigen-like domains 1 3.1026
CTSB cathepsin B 3.10236
TTLL5 tubulin tyrosine ligase-like family member 5 3.09883
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 3.09283
NLRP2 NLR family, pyrin domain containing 2 3.09192
CD34 CD34 molecule 3.09063
POM121L2 POM121 transmembrane nucleoporin-like 2 3.08983
SOX17 SRY (sex determining region Y)-box 17 3.08944
LUZP4 leucine zipper protein 4 3.08672
SCN3A sodium channel, voltage gated, type III alpha subunit 3.08302
FKBP1A FK506 binding protein 1A, 12kDa 3.07889
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 3.06633
TXNRD1 thioredoxin reductase 1 3.06179
GTDC1 glycosyltransferase-like domain containing 1 3.0575
MYOM2 myomesin 2 3.05561
ISL1 ISL LIM homeobox 1 3.05501
ADGRL2 adhesion G protein-coupled receptor L2 3.0507
BTG2 BTG family, member 2 3.0504
SLC26A10P solute carrier family 26 member 10, pseudogene 3.04856
TNF tumor necrosis factor 3.04715
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 3.03897
SKP1 S-phase kinase-associated protein 1 3.03754
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.03742
OAT ornithine aminotransferase 3.03382
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 3.02465
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 3.01795
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3.01371
ARHGAP33 Rho GTPase activating protein 33 3.00955
CUL3 cullin 3 3.00928
ARHGAP25 Rho GTPase activating protein 25 3.00348
REXO2 RNA exonuclease 2 3.00219

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -13.1891
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -9.03538
CREB1 cAMP responsive element binding protein 1 -6.27605
ATP5ME ATP synthase membrane subunit e -6.07561
SNCA synuclein, alpha (non A4 component of amyloid precursor) -5.87804
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.77235
POLI polymerase (DNA directed) iota -5.74077
TRAPPC3 trafficking protein particle complex 3 -5.4978
GRK4 G protein-coupled receptor kinase 4 -5.47141
KDM4D lysine (K)-specific demethylase 4D -5.43858
KPNA5 karyopherin alpha 5 (importin alpha 6) -5.41332
MINDY2 MINDY lysine 48 deubiquitinase 2 -5.2636
ERBB4 erb-b2 receptor tyrosine kinase 4 -5.25218
NELFA negative elongation factor complex member A -5.21148
FAM13A family with sequence similarity 13, member A -5.19878
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -5.13998
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 -5.13908
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -5.09162
MEF2C myocyte enhancer factor 2C -4.99835
THBD thrombomodulin -4.98781
AFAP1 actin filament associated protein 1 -4.87327
CXCL11 chemokine (C-X-C motif) ligand 11 -4.77523
REXO5 RNA exonuclease 5 -4.75777
RUBCN rubicon autophagy regulator -4.73517
CHTOP chromatin target of PRMT1 -4.7161
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -4.62563
USP34 ubiquitin specific peptidase 34 -4.61175
UBFD1 ubiquitin family domain containing 1 -4.55094
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -4.52859
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -4.52798
WASF1 WAS protein family, member 1 -4.52251
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator -4.50063
GRIK1 glutamate receptor, ionotropic, kainate 1 -4.49177
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -4.48284
KIDINS220 kinase D-interacting substrate, 220kDa -4.4406
ZC3H14 zinc finger CCCH-type containing 14 -4.43852
HLA-G major histocompatibility complex, class I, G -4.41674
ZNF711 zinc finger protein 711 -4.38985
OXA1L oxidase (cytochrome c) assembly 1-like -4.34152
RASA4 RAS p21 protein activator 4 -4.33611
TTC39A tetratricopeptide repeat domain 39A -4.32261
NXPE3 neurexophilin and PC-esterase domain family, member 3 -4.29762
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.25883
MCTP1 multiple C2 domains, transmembrane 1 -4.25416
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.23818
ZFPM2 zinc finger protein, FOG family member 2 -4.23493
MXI1 MAX interactor 1, dimerization protein -4.23365
KLF6 Kruppel-like factor 6 -4.19947
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -4.19518
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -4.19491
NHLH2 nescient helix loop helix 2 -4.16665
ETV7 ets variant 7 -4.15882
CD180 CD180 molecule -4.12817
PCF11 PCF11 cleavage and polyadenylation factor subunit -4.10275
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -4.09795
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -4.09737
SUMO3 small ubiquitin-like modifier 3 -4.09254
FBXL5 F-box and leucine-rich repeat protein 5 -4.08068
NEUROD1 neuronal differentiation 1 -4.07793
HAUS6 HAUS augmin-like complex, subunit 6 -4.07452
AVL9 AVL9 homolog (S. cerevisiase) -4.07022
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -4.06441
CYTH4 cytohesin 4 -4.02793
FST follistatin -4.01286
TIMP3 TIMP metallopeptidase inhibitor 3 -3.97362
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -3.94616
H3-3B H3.3 histone B -3.93991
TCP11 t-complex 11, testis-specific -3.93067
BACE2 beta-site APP-cleaving enzyme 2 -3.91848
EPHB1 EPH receptor B1 -3.91304
TRAF3IP3 TRAF3 interacting protein 3 -3.91015
ADAM2 ADAM metallopeptidase domain 2 -3.89533
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -3.89353
CSNK1G1 casein kinase 1, gamma 1 -3.88243
PNPO pyridoxamine 5'-phosphate oxidase -3.87967
CEP68 centrosomal protein 68kDa -3.87953
CAST calpastatin -3.87893
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -3.87493
PACS2 phosphofurin acidic cluster sorting protein 2 -3.87032
SH3YL1 SH3 and SYLF domain containing 1 -3.86701
RLN2 relaxin 2 -3.86342
RFX7 regulatory factor X, 7 -3.85757
VEZF1 vascular endothelial zinc finger 1 -3.85698
RBM47 RNA binding motif protein 47 -3.85184
TDRD7 tudor domain containing 7 -3.84637
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -3.83625
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -3.83467
PPL periplakin -3.83381
RPH3AL rabphilin 3A-like (without C2 domains) -3.83198
ASPHD1 aspartate beta-hydroxylase domain containing 1 -3.82801
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -3.82585
FER fer (fps/fes related) tyrosine kinase -3.81764
CLOCK clock circadian regulator -3.81463
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -3.81173
RAD54L2 RAD54-like 2 (S. cerevisiae) -3.8046
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -3.8014
OBSL1 obscurin-like 1 -3.78712
DEPP1 DEPP autophagy regulator 1 -3.78069
SLITRK5 SLIT and NTRK-like family, member 5 -3.77184
ZNF155 zinc finger protein 155 -3.76191
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.75811
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -3.75067
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -3.74442
OR7C1 olfactory receptor, family 7, subfamily C, member 1 -3.74214
MAP1B microtubule-associated protein 1B -3.73884
KANSL3 KAT8 regulatory NSL complex subunit 3 -3.73315
NSUN6 NOP2/Sun domain family, member 6 -3.73129
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -3.72374
UBA5 ubiquitin-like modifier activating enzyme 5 -3.71785
HLA-C major histocompatibility complex, class I, C -3.71291
WASF3 WAS protein family, member 3 -3.70056
RAD51C RAD51 paralog C -3.7005
ZNF34 zinc finger protein 34 -3.69304
MILR1 mast cell immunoglobulin-like receptor 1 -3.68663
CHN1 chimerin 1 -3.68124
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -3.67152
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.66084
PRMT8 protein arginine methyltransferase 8 -3.65667
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -3.65477
CSF1R colony stimulating factor 1 receptor -3.64526
AXIN1 axin 1 -3.64142
UCN urocortin -3.63269
OTOF otoferlin -3.62961
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -3.62268
TSPYL4 TSPY-like 4 -3.62095
MAP7 microtubule-associated protein 7 -3.61827
MAEA macrophage erythroblast attacher -3.61263
RTN4 reticulon 4 -3.61186
ZMYM6 zinc finger, MYM-type 6 -3.60531
BTN3A3 butyrophilin, subfamily 3, member A3 -3.6049
CSNK1G3 casein kinase 1, gamma 3 -3.59326
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -3.56797
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -3.56128
DOCK3 dedicator of cytokinesis 3 -3.55688
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -3.55682
HLA-F major histocompatibility complex, class I, F -3.55161
DLX4 distal-less homeobox 4 -3.543
KRI1 KRI1 homolog (S. cerevisiae) -3.51008
HEATR6 HEAT repeat containing 6 -3.50917
RBPJ recombination signal binding protein for immunoglobulin kappa J region -3.5087
METTL3 methyltransferase like 3 -3.50371
MYLK myosin light chain kinase -3.49141
FBXO41 F-box protein 41 -3.48869
MAP7D3 MAP7 domain containing 3 -3.48427
SAMHD1 SAM domain and HD domain 1 -3.48417
PRMT7 protein arginine methyltransferase 7 -3.47009
DMRT1 doublesex and mab-3 related transcription factor 1 -3.46823
GID4 GID complex subunit 4 -3.46598
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.45696
MCUB mitochondrial calcium uniporter dominant negative subunit beta -3.45231
CPE carboxypeptidase E -3.45024
HSPA4L heat shock 70kDa protein 4-like -3.44472
FAM193A family with sequence similarity 193, member A -3.4375
CCR2 chemokine (C-C motif) receptor 2 -3.43636
KCTD12 potassium channel tetramerization domain containing 12 -3.43417
CLU clusterin -3.43407
SIRT3 sirtuin 3 -3.42134
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -3.40927
SMAD3 SMAD family member 3 -3.40873
ARHGAP12 Rho GTPase activating protein 12 -3.40632
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -3.40486
ITGA7 integrin, alpha 7 -3.40469
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -3.40403
E2F2 E2F transcription factor 2 -3.40271
CYTH2 cytohesin 2 -3.39922
TTC4 tetratricopeptide repeat domain 4 -3.39524
AFDN-DT AFDN divergent transcript -3.39471
LCN1 lipocalin 1 -3.39136
LIMS2 LIM and senescent cell antigen-like domains 2 -3.37703
AK2 adenylate kinase 2 -3.36839
TBX1 T-box 1 -3.36338
CDC14A cell division cycle 14A -3.3625
CCDC181 coiled-coil domain containing 181 -3.36231
ZDHHC3 zinc finger, DHHC-type containing 3 -3.35331
EIPR1 EARP complex and GARP complex interacting protein 1 -3.34889
RREB1 ras responsive element binding protein 1 -3.34687
TUBGCP4 tubulin, gamma complex associated protein 4 -3.34203
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -3.33694
SASH1 SAM and SH3 domain containing 1 -3.33325
AUP1 ancient ubiquitous protein 1 -3.33192
MICA MHC class I polypeptide-related sequence A -3.32541
ZHX2 zinc fingers and homeoboxes 2 -3.32382
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -3.32359
CYFIP1 cytoplasmic FMR1 interacting protein 1 -3.31888
DPP8 dipeptidyl-peptidase 8 -3.31377
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -3.31017
GPM6A glycoprotein M6A -3.30468
POU6F2 POU class 6 homeobox 2 -3.30197
CRTC3 CREB regulated transcription coactivator 3 -3.30128
GLUL glutamate-ammonia ligase -3.2872
ITSN1 intersectin 1 (SH3 domain protein) -3.28609
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -3.28437
C22ORF31 chromosome 22 open reading frame 31 -3.28424
IL3RA interleukin 3 receptor, alpha (low affinity) -3.28412
ZFP69B ZFP69 zinc finger protein B -3.27566
PDE2A phosphodiesterase 2A, cGMP-stimulated -3.27326
MOCOS molybdenum cofactor sulfurase -3.27323
AKAP13 A kinase (PRKA) anchor protein 13 -3.25792
GDAP1 ganglioside induced differentiation associated protein 1 -3.25514
ADARB1 adenosine deaminase, RNA-specific, B1 -3.24985
ZNF273 zinc finger protein 273 -3.24297
TESMIN testis expressed metallothionein like protein -3.23615
DCC DCC netrin 1 receptor -3.23395
SEPTIN4 septin 4 -3.23069
DGKE diacylglycerol kinase, epsilon 64kDa -3.23006
PHF10 PHD finger protein 10 -3.22983
KHNYN KH and NYN domain containing -3.22333
YPEL1 yippee-like 1 (Drosophila) -3.21648
NKX2-1 NK2 homeobox 1 -3.21032
COQ8A coenzyme Q8A -3.20648
ANKLE2 ankyrin repeat and LEM domain containing 2 -3.20427
DTNA dystrobrevin, alpha -3.20214
H2BC11 H2B clustered histone 11 -3.19848
ECSIT ECSIT signalling integrator -3.1953
IFIH1 interferon induced with helicase C domain 1 -3.1934
HAUS3 HAUS augmin-like complex, subunit 3 -3.18809
NR2C2 nuclear receptor subfamily 2, group C, member 2 -3.18746
POMZP3 POM121 and ZP3 fusion -3.18277
PIP prolactin-induced protein -3.1801
PTBP2 polypyrimidine tract binding protein 2 -3.17892
ANKRD7 ankyrin repeat domain 7 -3.17256
GALR1 galanin receptor 1 -3.17123
TFF1 trefoil factor 1 -3.1706
SEPTIN10 septin 10 -3.16957
ZNF675 zinc finger protein 675 -3.16882
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide -3.1688
ADGRG6 adhesion G protein-coupled receptor G6 -3.16359
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -3.15184
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -3.1494
GBP1 guanylate binding protein 1, interferon-inducible -3.14537
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -3.1356
RADX RPA1 related single stranded DNA binding protein, X-linked -3.13362
THAP9 THAP domain containing 9 -3.13092
AOC3 amine oxidase, copper containing 3 -3.13075
LINS1 lines homolog 1 -3.13029
GPC5 glypican 5 -3.12426
UPK3B uroplakin 3B -3.12208
NOVA1 neuro-oncological ventral antigen 1 -3.11612
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -3.11488
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -3.10773
MYT1 myelin transcription factor 1 -3.10409
DOC2B double C2-like domains, beta -3.1035
ATXN7 ataxin 7 -3.1025
MYEF2 myelin expression factor 2 -3.09938
SH3BP2 SH3-domain binding protein 2 -3.09917
MMRN2 multimerin 2 -3.08963
GPX3 glutathione peroxidase 3 -3.08306
PLXDC1 plexin domain containing 1 -3.0824
IDI2-AS1 IDI2 antisense RNA 1 -3.08078
KIAA0040 KIAA0040 -3.07892
MSH3 mutS homolog 3 -3.07559
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.07196
PURA purine-rich element binding protein A -3.06612
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -3.06419
DCAF7 DDB1 and CUL4 associated factor 7 -3.06261
MBD4 methyl-CpG binding domain protein 4 -3.06205
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -3.05275
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -3.05134
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -3.05125
SENP7 SUMO1/sentrin specific peptidase 7 -3.04834
BCL2L11 BCL2-like 11 (apoptosis facilitator) -3.04465
RNF146 ring finger protein 146 -3.03638
GRAP GRB2-related adaptor protein -3.03593
BRCA2 breast cancer 2, early onset -3.03282
PEBP1 phosphatidylethanolamine binding protein 1 -3.02722
CX3CL1 chemokine (C-X3-C motif) ligand 1 -3.02586
ZNF385D zinc finger protein 385D -3.01749
FLNB filamin B, beta -3.015
MST1 macrophage stimulating 1 -3.01168
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -3.00861
DLG2 discs, large homolog 2 (Drosophila) -3.00558
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -3.00465
REEP1 receptor accessory protein 1 -3.00306
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -3.00074
MXD4 MAX dimerization protein 4 -3.00008