LIVF001-019 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

649 genes differentially expressed following the LIVF001-019 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 15.6819
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 13.5072
SNAP25 synaptosomal-associated protein, 25kDa 12.4824
MAMLD1 mastermind-like domain containing 1 10.481
TLR4 toll-like receptor 4 8.68323
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 7.31302
PRLR prolactin receptor 6.81345
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 6.68141
HIF3A hypoxia inducible factor 3, alpha subunit 6.17835
CASP7 caspase 7, apoptosis-related cysteine peptidase 6.09453
DERA deoxyribose-phosphate aldolase (putative) 5.90568
GFOD1 glucose-fructose oxidoreductase domain containing 1 5.59933
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5.41055
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 5.35898
OR10H1 olfactory receptor, family 10, subfamily H, member 1 5.35856
ING4 inhibitor of growth family, member 4 5.23492
MT4 metallothionein 4 5.23294
TKTL1 transketolase-like 1 5.2245
MYO1A myosin IA 5.19142
LRP6 low density lipoprotein receptor-related protein 6 5.13019
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 5.12779
NRG2 neuregulin 2 5.12613
PYCARD PYD and CARD domain containing 5.10024
ZCWPW1 zinc finger, CW type with PWWP domain 1 5.08357
LUZP2 leucine zipper protein 2 5.08035
TPT1 tumor protein, translationally-controlled 1 5.02975
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 5.01705
METTL22 methyltransferase like 22 4.9479
HDGFL3 HDGF like 3 4.9424
HRH2 histamine receptor H2 4.92185
TRHR thyrotropin-releasing hormone receptor 4.91654
ZNRF4 zinc and ring finger 4 4.83017
RUNDC3A RUN domain containing 3A 4.82662
MEP1A meprin A, alpha (PABA peptide hydrolase) 4.81664
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 4.7645
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 4.67194
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 4.66186
EDF1 endothelial differentiation-related factor 1 4.65644
RDH8 retinol dehydrogenase 8 (all-trans) 4.65641
PRM1 protamine 1 4.65083
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) 4.60127
TMEM187 transmembrane protein 187 4.59809
VIL1 villin 1 4.58126
ZNF133 zinc finger protein 133 4.55734
SYP synaptophysin 4.5534
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 4.54476
GHRHR growth hormone releasing hormone receptor 4.54025
IL17RB interleukin 17 receptor B 4.53748
KLHL1 kelch-like family member 1 4.52407
APAF1 apoptotic peptidase activating factor 1 4.51688
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 4.51458
MYO15A myosin XVA 4.50339
GPR75 G protein-coupled receptor 75 4.49389
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 4.46916
CCL25 chemokine (C-C motif) ligand 25 4.46741
LRRC36 leucine rich repeat containing 36 4.46523
APOLD1 apolipoprotein L domain containing 1 4.45796
HLA-DOA major histocompatibility complex, class II, DO alpha 4.45364
RBBP7 retinoblastoma binding protein 7 4.43399
HNF4A hepatocyte nuclear factor 4, alpha 4.42989
TMSB4Y thymosin beta 4, Y-linked 4.42877
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 4.40107
GUCY2C guanylate cyclase 2C 4.40014
EOLA2-DT EOLA2 divergent transcript 4.37451
PARP6 poly (ADP-ribose) polymerase family, member 6 4.37363
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 4.35759
FGR FGR proto-oncogene, Src family tyrosine kinase 4.34585
FPR2 formyl peptide receptor 2 4.34023
CAV3 caveolin 3 4.33474
CETN1 centrin, EF-hand protein, 1 4.33085
GLP1R glucagon-like peptide 1 receptor 4.32546
RBM17 RNA binding motif protein 17 4.29863
GRIA4 glutamate receptor, ionotropic, AMPA 4 4.29804
ACTL7B actin-like 7B 4.28531
CNR2 cannabinoid receptor 2 (macrophage) 4.27714
OLAH oleoyl-ACP hydrolase 4.26516
GPR37L1 G protein-coupled receptor 37 like 1 4.25761
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 4.2198
SYT2 synaptotagmin II 4.20818
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 4.20582
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 4.19547
KRT3 keratin 3, type II 4.18428
CCL7 chemokine (C-C motif) ligand 7 4.18244
BIRC7 baculoviral IAP repeat containing 7 4.1518
TCP10L t-complex 10-like 4.14005
MED31 mediator complex subunit 31 4.12394
SMR3B submaxillary gland androgen regulated protein 3B 4.11814
EDA2R ectodysplasin A2 receptor 4.10847
IGSF1 immunoglobulin superfamily, member 1 4.09979
KSR1 kinase suppressor of ras 1 4.08835
GIP gastric inhibitory polypeptide 4.08682
CYSLTR2 cysteinyl leukotriene receptor 2 4.08007
C22ORF31 chromosome 22 open reading frame 31 4.05787
GPR32 G protein-coupled receptor 32 4.04617
IPO8 importin 8 4.03553
VSNL1 visinin-like 1 4.02424
DAPK2 death-associated protein kinase 2 4.02244
ESM1 endothelial cell-specific molecule 1 4.01562
HYAL4 hyaluronoglucosaminidase 4 4.00742
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 4.00458
AP3B2 adaptor-related protein complex 3, beta 2 subunit 4.00408
FABP1 fatty acid binding protein 1, liver 4.00163
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 3.99326
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 3.98108
UBB ubiquitin B 3.97706
TLX1 T-cell leukemia homeobox 1 3.97482
CALCRL calcitonin receptor-like 3.97218
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3.9608
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.94731
TEX13B testis expressed 13B 3.94446
TLR8 toll-like receptor 8 3.94122
RPL13A ribosomal protein L13a 3.93854
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 3.93377
OR12D3 olfactory receptor, family 12, subfamily D, member 3 3.93197
SNAP91 synaptosomal-associated protein, 91kDa 3.91434
RAMP2 receptor (G protein-coupled) activity modifying protein 2 3.91357
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 3.90593
ZNF384 zinc finger protein 384 3.90126
TREM1 triggering receptor expressed on myeloid cells 1 3.88896
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 3.88578
IL12RB1 interleukin 12 receptor, beta 1 3.87204
UNC5C unc-5 homolog C (C. elegans) 3.87145
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 3.86945
NCF2 neutrophil cytosolic factor 2 3.86331
RNF43 ring finger protein 43 3.85552
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 3.85381
AOC4P amine oxidase, copper containing 4, pseudogene 3.85379
DCTN4 dynactin 4 (p62) 3.85328
ACKR2 atypical chemokine receptor 2 3.83819
ZNF710 zinc finger protein 710 3.82935
KHSRP KH-type splicing regulatory protein 3.82694
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 3.7874
KANSL3 KAT8 regulatory NSL complex subunit 3 3.78299
YES1 YES proto-oncogene 1, Src family tyrosine kinase 3.77379
RXRG retinoid X receptor, gamma 3.77216
PRPF4 pre-mRNA processing factor 4 3.76739
HLA-F-AS1 HLA-F antisense RNA 1 3.76628
HNF1A HNF1 homeobox A 3.76498
SYN1 synapsin I 3.75048
CRLF2 cytokine receptor-like factor 2 3.746
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 3.74134
AKAP6 A kinase (PRKA) anchor protein 6 3.73583
SCN5A sodium channel, voltage gated, type V alpha subunit 3.73395
TCP11 t-complex 11, testis-specific 3.73123
CD300C CD300c molecule 3.72804
NRIP3 nuclear receptor interacting protein 3 3.72719
ADIRF adipogenesis regulatory factor 3.7226
NR5A2 nuclear receptor subfamily 5, group A, member 2 3.72007
ANOS1 anosmin 1 3.70254
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 3.70069
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 3.69272
MPP1 membrane protein, palmitoylated 1, 55kDa 3.68526
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 3.68467
IKZF4 IKAROS family zinc finger 4 (Eos) 3.68197
RPL8 ribosomal protein L8 3.67964
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 3.67895
SLC17A4 solute carrier family 17, member 4 3.67756
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.67399
METTL25B methyltransferase like 25B 3.66903
CCL17 chemokine (C-C motif) ligand 17 3.66778
ERBB4 erb-b2 receptor tyrosine kinase 4 3.6613
SPANXD SPANX family, member D 3.65917
CLCN1 chloride channel, voltage-sensitive 1 3.65657
SEC24D SEC24 family member D 3.65265
DPEP3 dipeptidase 3 3.64077
TBXT T-box transcription factor T 3.63918
SPEG SPEG complex locus 3.63864
EPS8 epidermal growth factor receptor pathway substrate 8 3.63755
IQSEC3 IQ motif and Sec7 domain 3 3.63732
RAB31 RAB31, member RAS oncogene family 3.62464
TDRD1 tudor domain containing 1 3.61976
SIX6 SIX homeobox 6 3.61801
TAPT1 transmembrane anterior posterior transformation 1 3.61294
PSORS1C2 psoriasis susceptibility 1 candidate 2 3.61189
TRO trophinin 3.61186
ESR1 estrogen receptor 1 3.59891
ARHGAP26 Rho GTPase activating protein 26 3.59701
TMLHE trimethyllysine hydroxylase, epsilon 3.59291
INKA2 inka box actin regulator 2 3.58759
ADI1 acireductone dioxygenase 1 3.55768
FLT4 fms-related tyrosine kinase 4 3.55288
GJD2 gap junction protein, delta 2, 36kDa 3.55194
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 3.55148
VAV3 vav 3 guanine nucleotide exchange factor 3.55101
POLL polymerase (DNA directed), lambda 3.54955
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 3.54658
CDH13 cadherin 13 3.54259
MOGAT2 monoacylglycerol O-acyltransferase 2 3.53884
RFTN1 raftlin, lipid raft linker 1 3.53345
CHP2 calcineurin-like EF-hand protein 2 3.52179
MEP1B meprin A, beta 3.51623
GRAP GRB2-related adaptor protein 3.51273
THRB thyroid hormone receptor, beta 3.50871
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.50096
SPTB spectrin, beta, erythrocytic 3.49055
GATA6 GATA binding protein 6 3.48736
DSPP dentin sialophosphoprotein 3.48472
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.4789
RGSL1 regulator of G-protein signaling like 1 3.4788
RPL27 ribosomal protein L27 3.47648
GLCE glucuronic acid epimerase 3.47242
STK38L serine/threonine kinase 38 like 3.47071
SAMD14 sterile alpha motif domain containing 14 3.46391
ADRA2B adrenoceptor alpha 2B 3.46197
TFDP3 transcription factor Dp family, member 3 3.45498
NOD2 nucleotide-binding oligomerization domain containing 2 3.45428
SPP1 secreted phosphoprotein 1 3.45299
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 3.43828
RPA4 replication protein A4, 30kDa 3.43793
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 3.43675
STRAP serine/threonine kinase receptor associated protein 3.43333
TAGLN3 transgelin 3 3.42898
DRD5 dopamine receptor D5 3.42624
PRSS21 protease, serine, 21 (testisin) 3.42471
CYBRD1 cytochrome b reductase 1 3.41941
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.41819
MRPS16 mitochondrial ribosomal protein S16 3.41287
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 3.4107
ACSL6 acyl-CoA synthetase long-chain family member 6 3.409
RPS2 ribosomal protein S2 3.40745
DNAH17 dynein, axonemal, heavy chain 17 3.40485
PLSCR4 phospholipid scramblase 4 3.40457
RAB40A RAB40A, member RAS oncogene family 3.40347
OBP2A odorant binding protein 2A 3.39955
NHLRC2 NHL repeat containing 2 3.39914
CDHR2 cadherin-related family member 2 3.39833
HUNK hormonally up-regulated Neu-associated kinase 3.39618
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 3.39579
MTHFSD methenyltetrahydrofolate synthetase domain containing 3.39203
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 3.38852
EFCAB6 EF-hand calcium binding domain 6 3.38839
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 3.38643
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 3.38611
ESPN espin 3.38199
AADAC arylacetamide deacetylase 3.38044
NOVA2 neuro-oncological ventral antigen 2 3.37508
PELI2 pellino E3 ubiquitin protein ligase family member 2 3.37468
OR1A1 olfactory receptor, family 1, subfamily A, member 1 3.36656
ZNF516 zinc finger protein 516 3.36167
APOA4 apolipoprotein A-IV 3.35962
UBAP2 ubiquitin associated protein 2 3.35957
DOK5 docking protein 5 3.35838
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 3.35351
LDOC1 leucine zipper, down-regulated in cancer 1 3.3533
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.35197
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.34841
OR7C2 olfactory receptor, family 7, subfamily C, member 2 3.34493
CA7 carbonic anhydrase VII 3.34006
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.33865
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.33749
GJA4 gap junction protein, alpha 4, 37kDa 3.33699
SEZ6L seizure related 6 homolog (mouse)-like 3.33645
WBP11 WW domain binding protein 11 3.33617
SLC66A1 solute carrier family 66 member 1 3.33174
RGS7 regulator of G-protein signaling 7 3.33137
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 3.32761
CEP85 centrosomal protein 85kDa 3.32554
CDH17 cadherin 17, LI cadherin (liver-intestine) 3.3248
SRPK3 SRSF protein kinase 3 3.32335
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 3.32128
CDX2 caudal type homeobox 2 3.31726
SEPTIN10 septin 10 3.31473
TP53TG5 TP53 target 5 3.313
GLRB glycine receptor, beta 3.3109
SRSF5 serine/arginine-rich splicing factor 5 3.30611
GRIK1 glutamate receptor, ionotropic, kainate 1 3.30474
AFD1 acrofacial dysostosis 1, Nager type 3.30034
NUCB2 nucleobindin 2 3.29447
LRRN3 leucine rich repeat neuronal 3 3.29323
RAD51C RAD51 paralog C 3.29201
PHF7 PHD finger protein 7 3.28956
CMKLR1 chemerin chemokine-like receptor 1 3.28886
TBC1D2 TBC1 domain family, member 2 3.28855
UBQLN3 ubiquilin 3 3.28818
TAPBPL TAP binding protein-like 3.2879
ZPBP zona pellucida binding protein 3.28719
IL33R interleukin 33 receptor 3.28523
STAC SH3 and cysteine rich domain 3.28505
NEK3 NIMA-related kinase 3 3.28273
CYRIA CYFIP related Rac1 interactor A 3.28064
CPNE6 copine VI (neuronal) 3.2794
CD101 CD101 molecule 3.27776
STX16 syntaxin 16 3.25955
ADIPOR2 adiponectin receptor 2 3.25409
CER1 cerberus 1, DAN family BMP antagonist 3.25206
OSGIN1 oxidative stress induced growth inhibitor 1 3.25177
MELTF melanotransferrin 3.25026
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 3.24836
CIITA class II, major histocompatibility complex, transactivator 3.24782
SPAG8 sperm associated antigen 8 3.24664
TRIM37 tripartite motif containing 37 3.24591
GPA33 glycoprotein A33 (transmembrane) 3.2427
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 3.24162
ADGRE1 adhesion G protein-coupled receptor E1 3.23853
SRRM2 serine/arginine repetitive matrix 2 3.23741
CELA3A chymotrypsin-like elastase family, member 3A 3.2371
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 3.23657
HK3 hexokinase 3 (white cell) 3.23613
MAGEA11 melanoma antigen family A11 3.23299
JCAD junctional cadherin 5 associated 3.23219
LDHC lactate dehydrogenase C 3.22714
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 3.22638
IL17B interleukin 17B 3.22542
CHGB chromogranin B 3.22518
TOP3A topoisomerase (DNA) III alpha 3.21967
RPSA ribosomal protein SA 3.21882
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.21654
CLCA1 chloride channel accessory 1 3.20943
ARHGAP29 Rho GTPase activating protein 29 3.19665
CD1B CD1b molecule 3.1962
VSTM4 V-set and transmembrane domain containing 4 3.19245
ANKRD40CL ANKRD40 C-terminal like 3.19016
IL5 interleukin 5 3.18664
CNTN1 contactin 1 3.18607
CRYBB2 crystallin, beta B2 3.1855
SLC39A6 solute carrier family 39 (zinc transporter), member 6 3.18059
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 3.1798
C17ORF80 chromosome 17 open reading frame 80 3.17938
PDE3A phosphodiesterase 3A, cGMP-inhibited 3.17921
RANBP17 RAN binding protein 17 3.17841
GPR107 G protein-coupled receptor 107 3.17625
ATF6B activating transcription factor 6 beta 3.17514
PRDM11 PR domain containing 11 3.17219
CABP2 calcium binding protein 2 3.17131
PKD2L1 polycystic kidney disease 2-like 1 3.17017
GLE1 GLE1 RNA export mediator 3.17006
PGM3 phosphoglucomutase 3 3.16633
PDCD1LG2 programmed cell death 1 ligand 2 3.16446
KIF5A kinesin family member 5A 3.1597
OR7A5 olfactory receptor, family 7, subfamily A, member 5 3.15897
MRAS muscle RAS oncogene homolog 3.15634
RPS5 ribosomal protein S5 3.15615
ACSL5 acyl-CoA synthetase long-chain family member 5 3.15526
HEXA hexosaminidase A (alpha polypeptide) 3.15456
NDRG4 NDRG family member 4 3.15233
ARR3 arrestin 3, retinal (X-arrestin) 3.14867
STMN2 stathmin 2 3.14662
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 3.14656
RPS8 ribosomal protein S8 3.14574
CEP192 centrosomal protein 192kDa 3.14412
POLB polymerase (DNA directed), beta 3.14324
WFDC8 WAP four-disulfide core domain 8 3.14228
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.14052
RPL4 ribosomal protein L4 3.13622
DRD2 dopamine receptor D2 3.13532
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 3.13492
FUBP3 far upstream element (FUSE) binding protein 3 3.13468
ADGRB1 adhesion G protein-coupled receptor B1 3.13394
NCKAP1L NCK-associated protein 1-like 3.13324
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 3.12773
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 3.12465
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 3.12251
ANKRD53 ankyrin repeat domain 53 3.12082
ODAD2 outer dynein arm docking complex subunit 2 3.12036
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 3.1201
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 3.11718
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.11596
GPR52 G protein-coupled receptor 52 3.11452
CA6 carbonic anhydrase VI 3.11407
ADGRL4 adhesion G protein-coupled receptor L4 3.11002
MAB21L1 mab-21-like 1 (C. elegans) 3.10883
ST20 suppressor of tumorigenicity 20 3.10592
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 3.10553
PLCD1 phospholipase C, delta 1 3.10512
FGF5 fibroblast growth factor 5 3.10461
GSTA1 glutathione S-transferase alpha 1 3.10198
MUC13 mucin 13, cell surface associated 3.09852
CCL8 chemokine (C-C motif) ligand 8 3.09578
PDE5A phosphodiesterase 5A, cGMP-specific 3.09514
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 3.09513
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 3.09222
GAB1 GRB2-associated binding protein 1 3.09126
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 3.09046
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 3.08532
DRG1 developmentally regulated GTP binding protein 1 3.08498
PAXBP1 PAX3 and PAX7 binding protein 1 3.07984
MEF2C myocyte enhancer factor 2C 3.07587
FRS3 fibroblast growth factor receptor substrate 3 3.0747
TESMIN testis expressed metallothionein like protein 3.07449
NKX6-1 NK6 homeobox 1 3.07223
ZNF155 zinc finger protein 155 3.06684
RPL17 ribosomal protein L17 3.06296
RAB11FIP3 RAB11 family interacting protein 3 (class II) 3.06289
GSTM4 glutathione S-transferase mu 4 3.0623
PROSER1 proline and serine rich 1 3.06096
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 3.05934
FGF20 fibroblast growth factor 20 3.0572
MYT1 myelin transcription factor 1 3.05678
SLC35G2 solute carrier family 35, member G2 3.05606
ODF1 outer dense fiber of sperm tails 1 3.05001
THBD thrombomodulin 3.04395
ATP5IF1 ATP synthase inhibitory factor subunit 1 3.04348
TG thyroglobulin 3.04323
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.04223
ACVRL1 activin A receptor type II-like 1 3.04147
SOAT2 sterol O-acyltransferase 2 3.04135
OR2H2 olfactory receptor, family 2, subfamily H, member 2 3.03739
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 3.03639
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 3.03633
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 3.03607
RIMS2 regulating synaptic membrane exocytosis 2 3.03136
INTS14 integrator complex subunit 14 3.03001
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.02947
ATP10B ATPase, class V, type 10B 3.02635
PLCB4 phospholipase C, beta 4 3.02325
MYL7 myosin, light chain 7, regulatory 3.02251
CATSPERZ catsper channel auxiliary subunit zeta 3.02119
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.01161
RPL7A ribosomal protein L7a 3.00912
ZFHX2 zinc finger homeobox 2 3.00445
CXCR1 chemokine (C-X-C motif) receptor 1 3.00438
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 3.00219
CES1P1 carboxylesterase 1 pseudogene 1 3.00077

decreased expression

Symbol Name Standardized Value
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -10.6911
NUSAP1 nucleolar and spindle associated protein 1 -8.12168
CAST calpastatin -7.93863
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.66792
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -7.39098
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -7.26129
STAT1 signal transducer and activator of transcription 1, 91kDa -6.98939
CRK v-crk avian sarcoma virus CT10 oncogene homolog -6.80514
DUSP3 dual specificity phosphatase 3 -6.11682
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -6.07065
RAI14 retinoic acid induced 14 -6.06985
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -5.61646
RUNX3 runt-related transcription factor 3 -5.50603
SDC1 syndecan 1 -5.2252
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -4.99425
FBXO11 F-box protein 11 -4.84036
ADRB2 adrenoceptor beta 2, surface -4.75855
WDR82 WD repeat domain 82 -4.66077
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -4.65677
PIAS3 protein inhibitor of activated STAT, 3 -4.63675
SYNE1 spectrin repeat containing, nuclear envelope 1 -4.52934
IQCE IQ motif containing E -4.47387
BAD BCL2-associated agonist of cell death -4.46162
BRD3OS BRD3 opposite strand -4.45198
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -4.44021
ZNHIT2 zinc finger, HIT-type containing 2 -4.43964
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -4.41823
C1R complement component 1, r subcomponent -4.41292
TMEM45A transmembrane protein 45A -4.40522
SOD2 superoxide dismutase 2, mitochondrial -4.37334
LRRC8E leucine rich repeat containing 8 family, member E -4.36294
NUP62CL nucleoporin 62kDa C-terminal like -4.34584
NCOA1 nuclear receptor coactivator 1 -4.34325
CREB1 cAMP responsive element binding protein 1 -4.27976
C4ORF19 chromosome 4 open reading frame 19 -4.27324
ZNF271P zinc finger protein 271, pseudogene -4.24166
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -4.23952
HOXB13 homeobox B13 -4.22896
IL16 interleukin 16 -4.18213
RGS17 regulator of G-protein signaling 17 -4.16169
CRYGB crystallin, gamma B -4.15711
CADM1 cell adhesion molecule 1 -4.1487
PHLDA3 pleckstrin homology-like domain, family A, member 3 -4.14297
ZC3H12A zinc finger CCCH-type containing 12A -4.14194
NINJ1 ninjurin 1 -4.14153
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -4.13814
C1S complement component 1, s subcomponent -4.13057
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -4.10404
EDA ectodysplasin A -4.10305
CCNE1 cyclin E1 -4.09905
GPRC5C G protein-coupled receptor, class C, group 5, member C -4.09323
NEK4 NIMA-related kinase 4 -4.06682
IGFLR1 IGF-like family receptor 1 -4.05357
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -4.04189
JAM3 junctional adhesion molecule 3 -4.02947
HK1 hexokinase 1 -4.02864
ACAD8 acyl-CoA dehydrogenase family, member 8 -4.02281
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -4.01034
SPON2 spondin 2, extracellular matrix protein -3.9792
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -3.96844
LBH limb bud and heart development -3.9451
SLC49A3 solute carrier family 49 member 3 -3.92001
TTC9 tetratricopeptide repeat domain 9 -3.91411
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -3.91174
TTC26 tetratricopeptide repeat domain 26 -3.90746
BEX4 brain expressed, X-linked 4 -3.88617
PITPNA phosphatidylinositol transfer protein, alpha -3.88444
ZNF460 zinc finger protein 460 -3.87394
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -3.87124
BNC2 basonuclin 2 -3.85059
C14ORF93 chromosome 14 open reading frame 93 -3.84073
C12ORF43 chromosome 12 open reading frame 43 -3.82702
KMT2A lysine (K)-specific methyltransferase 2A -3.79717
MRPL4 mitochondrial ribosomal protein L4 -3.78024
ARHGAP45 Rho GTPase activating protein 45 -3.7773
RAP2B RAP2B, member of RAS oncogene family -3.76967
SBNO1 strawberry notch homolog 1 (Drosophila) -3.76617
ZNF208 zinc finger protein 208 -3.7493
KLF13 Kruppel-like factor 13 -3.74387
PIERCE1 piercer of microtubule wall 1 -3.74162
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -3.73624
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -3.72832
CRNN cornulin -3.72674
KDSR 3-ketodihydrosphingosine reductase -3.72667
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -3.72459
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -3.72304
TRIM68 tripartite motif containing 68 -3.72249
POU2AF1 POU class 2 associating factor 1 -3.71512
TCTN1 tectonic family member 1 -3.71181
EHD4 EH-domain containing 4 -3.70329
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -3.6851
ZMPSTE24 zinc metallopeptidase STE24 -3.68074
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -3.68012
MCUB mitochondrial calcium uniporter dominant negative subunit beta -3.67867
TMPRSS11E transmembrane protease, serine 11E -3.67458
EFHC1 EF-hand domain (C-terminal) containing 1 -3.67452
EML1 echinoderm microtubule associated protein like 1 -3.65732
PDE1B phosphodiesterase 1B, calmodulin-dependent -3.64983
MOXD1 monooxygenase, DBH-like 1 -3.63963
UFSP2 UFM1-specific peptidase 2 -3.63645
IFT22 intraflagellar transport 22 -3.63622
PEX12 peroxisomal biogenesis factor 12 -3.63139
TRIB2 tribbles pseudokinase 2 -3.6218
CSNK1G2 casein kinase 1, gamma 2 -3.61356
EVL Enah/Vasp-like -3.60098
ZNF106 zinc finger protein 106 -3.60025
MITF microphthalmia-associated transcription factor -3.59915
SEPTIN11 septin 11 -3.59164
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -3.59012
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -3.58402
PDE9A phosphodiesterase 9A -3.5825
KANK2 KN motif and ankyrin repeat domains 2 -3.57926
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -3.56995
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -3.55897
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -3.54361
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -3.53578
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -3.53069
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -3.52946
JUNB jun B proto-oncogene -3.52936
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -3.52594
ZNF232 zinc finger protein 232 -3.52008
FAM86C1P family with sequence similarity 86 member C1, pseudogene -3.51537
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -3.51518
JMJD7 jumonji domain containing 7 -3.51133
REXO2 RNA exonuclease 2 -3.50858
BAIAP2 BAI1-associated protein 2 -3.50339
IFRD2 interferon-related developmental regulator 2 -3.49261
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -3.49055
IRF9 interferon regulatory factor 9 -3.48585
PSCA prostate stem cell antigen -3.4702
TMEM39B transmembrane protein 39B -3.457
RHOG ras homolog family member G -3.45113
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.45039
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -3.44814
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -3.43351
TRAF3 TNF receptor-associated factor 3 -3.42619
TUBG1 tubulin, gamma 1 -3.42432
UST uronyl-2-sulfotransferase -3.41809
SOBP sine oculis binding protein homolog (Drosophila) -3.41599
ZNF264 zinc finger protein 264 -3.40706
RIPK4 receptor-interacting serine-threonine kinase 4 -3.40271
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 -3.40191
RAB11FIP2 RAB11 family interacting protein 2 (class I) -3.40175
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -3.39929
FOLR2 folate receptor 2 (fetal) -3.39757
PIMREG PICALM interacting mitotic regulator -3.39725
BMP8B bone morphogenetic protein 8b -3.39692
NKX3-1 NK3 homeobox 1 -3.38366
STK39 serine threonine kinase 39 -3.38002
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -3.37776
BLNK B-cell linker -3.37154
TMEM106B transmembrane protein 106B -3.36992
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 -3.36061
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -3.35332
KIF3B kinesin family member 3B -3.35183
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -3.33504
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -3.33265
HOXA1 homeobox A1 -3.33241
ERBIN erbb2 interacting protein -3.32878
PRSS22 protease, serine, 22 -3.32829
NT5DC2 5'-nucleotidase domain containing 2 -3.32673
PTGER4 prostaglandin E receptor 4 (subtype EP4) -3.32477
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -3.31683
SPINK5 serine peptidase inhibitor, Kazal type 5 -3.31597
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -3.30966
STOML1 stomatin (EPB72)-like 1 -3.29713
MXRA7 matrix-remodelling associated 7 -3.29512
SBF1 SET binding factor 1 -3.28622
FSD1 fibronectin type III and SPRY domain containing 1 -3.28535
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -3.27695
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -3.27579
FHIT fragile histidine triad -3.26336
S100A9 S100 calcium binding protein A9 -3.26292
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -3.26282
AKIRIN1 akirin 1 -3.25947
ACTN1 actinin, alpha 1 -3.25351
BPHL biphenyl hydrolase-like (serine hydrolase) -3.25246
POMZP3 POM121 and ZP3 fusion -3.24609
MSL2 male-specific lethal 2 homolog (Drosophila) -3.24476
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.24088
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -3.23347
MMP10 matrix metallopeptidase 10 -3.22788
CLDN7 claudin 7 -3.22788
NKX3-2 NK3 homeobox 2 -3.22679
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -3.21777
S100A7 S100 calcium binding protein A7 -3.21258
DSTYK dual serine/threonine and tyrosine protein kinase -3.20714
TENM3 teneurin transmembrane protein 3 -3.20552
SKAP2 src kinase associated phosphoprotein 2 -3.20475
PPID peptidylprolyl isomerase D -3.18167
TUSC2 tumor suppressor candidate 2 -3.17995
CLDN8 claudin 8 -3.17651
LCMT2 leucine carboxyl methyltransferase 2 -3.16885
NME7 NME/NM23 family member 7 -3.166
ZNF711 zinc finger protein 711 -3.15579
NEIL1 nei endonuclease VIII-like 1 (E. coli) -3.15446
TSPAN1 tetraspanin 1 -3.14499
NME6 NME/NM23 nucleoside diphosphate kinase 6 -3.1358
TDRD3 tudor domain containing 3 -3.13278
PYCR3 pyrroline-5-carboxylate reductase 3 -3.12472
DLD dihydrolipoamide dehydrogenase -3.11955
ALMS1 Alstrom syndrome protein 1 -3.11913
ARHGAP25 Rho GTPase activating protein 25 -3.1113
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -3.10713
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -3.1059
KLF2 Kruppel-like factor 2 -3.09952
S100B S100 calcium binding protein B -3.09549
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -3.0943
PDZK1IP1 PDZK1 interacting protein 1 -3.09348
MAPKBP1 mitogen-activated protein kinase binding protein 1 -3.09015
EZR ezrin -3.0878
CLCA2 chloride channel accessory 2 -3.08745
CTSB cathepsin B -3.08404
ATXN10 ataxin 10 -3.08308
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -3.0816
OLFML2B olfactomedin-like 2B -3.07922
MZB1 marginal zone B and B1 cell-specific protein -3.07797
STX6 syntaxin 6 -3.07325
ITM2C integral membrane protein 2C -3.07266
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -3.07017
NLRX1 NLR family member X1 -3.06868
SCMH1 sex comb on midleg homolog 1 (Drosophila) -3.06742
COBLL1 cordon-bleu WH2 repeat protein-like 1 -3.06437
SPATA5L1 spermatogenesis associated 5-like 1 -3.05951
LRRC31 leucine rich repeat containing 31 -3.05152
MAN1C1 mannosidase, alpha, class 1C, member 1 -3.04728
TMEM115 transmembrane protein 115 -3.04164
POLM polymerase (DNA directed), mu -3.02785
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -3.02578
LHX5 LIM homeobox 5 -3.01726
JMJD4 jumonji domain containing 4 -3.01536
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -3.01524
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -3.01293
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -3.00375
EMILIN1 elastin microfibril interfacer 1 -3.00297
H1-3 H1.3 linker histone, cluster member -3.00076