LIVF001-022 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

562 genes differentially expressed following the LIVF001-022 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 16.2515
PFKL phosphofructokinase, liver 14.9701
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 7.48601
GATD3 glutamine amidotransferase class 1 domain containing 3 7.08323
AOC4P amine oxidase, copper containing 4, pseudogene 5.44837
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 5.35031
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 5.23655
ICOSLG inducible T-cell co-stimulator ligand 5.21505
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 5.09377
SAP30L-AS1 SAP30L antisense RNA 1 (head to head) 5.07783
ELOB elongin B 5.07589
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 5.01924
CORO7 coronin 7 4.99916
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 4.96668
TBCE tubulin folding cofactor E 4.92576
ATP11A ATPase, class VI, type 11A 4.83541
PNLIPRP1 pancreatic lipase-related protein 1 4.76827
MTMR14 myotubularin related protein 14 4.68253
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 4.67585
CD28 CD28 molecule 4.63559
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 4.60144
ZFHX4 zinc finger homeobox 4 4.56233
FAM110D family with sequence similarity 110, member D 4.5547
PTCH1 patched 1 4.54618
TYK2 tyrosine kinase 2 4.53288
PFN1 profilin 1 4.49246
MTNR1A melatonin receptor 1A 4.4592
ZNF254 zinc finger protein 254 4.43844
HMGXB3 HMG box domain containing 3 4.43261
MPZ myelin protein zero 4.4241
RRBP1 ribosome binding protein 1 4.41792
PDZD2 PDZ domain containing 2 4.39498
ZNF142 zinc finger protein 142 4.3722
OVOL2 ovo-like zinc finger 2 4.36543
ATAD2B ATPase family, AAA domain containing 2B 4.36371
WDR33 WD repeat domain 33 4.31541
TNN tenascin N 4.30992
CLIP2 CAP-GLY domain containing linker protein 2 4.24768
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 4.23064
NCALD neurocalcin delta 4.21808
MLH3 mutL homolog 3 4.21543
FGF1 fibroblast growth factor 1 (acidic) 4.18228
H2BC3 H2B clustered histone 3 4.16205
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.14005
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 4.13441
PCNT pericentrin 4.1138
NRTN neurturin 4.09958
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 4.0895
FMNL1 formin-like 1 4.07592
LZTS3 leucine zipper, putative tumor suppressor family member 3 4.0703
ZC3H7A zinc finger CCCH-type containing 7A 4.06748
GP5 glycoprotein V (platelet) 4.04709
PDE3B phosphodiesterase 3B, cGMP-inhibited 4.02732
C1ORF50 chromosome 1 open reading frame 50 4.00761
PNPLA2 patatin-like phospholipase domain containing 2 3.99179
EXO5 exonuclease 5 3.97213
SIPA1L3 signal-induced proliferation-associated 1 like 3 3.97121
FTH1 ferritin, heavy polypeptide 1 3.95323
MNX1 motor neuron and pancreas homeobox 1 3.93082
SHOX2 short stature homeobox 2 3.91635
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.91606
STXBP6 syntaxin binding protein 6 (amisyn) 3.91568
ZFP36L1 ZFP36 ring finger protein-like 1 3.90389
DDRGK1 DDRGK domain containing 1 3.89717
CDK11A cyclin-dependent kinase 11A 3.88763
PTP4A3 protein tyrosine phosphatase type IVA, member 3 3.88452
CPT1A carnitine palmitoyltransferase 1A (liver) 3.87416
PRMT2 protein arginine methyltransferase 2 3.86507
RNF216 ring finger protein 216 3.85704
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 3.85463
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 3.85145
H1-4 H1.4 linker histone, cluster member 3.85028
NTHL1 nth endonuclease III-like 1 (E. coli) 3.8463
POFUT2 protein O-fucosyltransferase 2 3.84108
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.80685
GPX1 glutathione peroxidase 1 3.8036
PPP6R3 protein phosphatase 6, regulatory subunit 3 3.79731
RHOB ras homolog family member B 3.78634
GALC galactosylceramidase 3.77728
EIF3K eukaryotic translation initiation factor 3, subunit K 3.77626
MT1X metallothionein 1X 3.77046
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 3.75782
SUCLG1 succinate-CoA ligase, alpha subunit 3.75748
ZNF675 zinc finger protein 675 3.74851
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 3.74041
H2AC6 H2A clustered histone 6 3.73518
BRWD1 bromodomain and WD repeat domain containing 1 3.73448
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1 3.73411
NKX2-2 NK2 homeobox 2 3.71969
IQSEC1 IQ motif and Sec7 domain 1 3.70626
H2BC14 H2B clustered histone 14 3.7052
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 3.69882
MCM3AP minichromosome maintenance complex component 3 associated protein 3.698
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 3.68118
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.67787
TPP2 tripeptidyl peptidase II 3.66816
ATP2A3 ATPase, Ca++ transporting, ubiquitous 3.64768
BMP8B bone morphogenetic protein 8b 3.63091
TELO2 telomere maintenance 2 3.62541
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 3.62538
ADI1 acireductone dioxygenase 1 3.62346
CELA3A chymotrypsin-like elastase family, member 3A 3.6226
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 3.61056
CDC14A cell division cycle 14A 3.60997
OR7C1 olfactory receptor, family 7, subfamily C, member 1 3.60719
LRRC75B leucine rich repeat containing 75B 3.59562
TRAPPC10 trafficking protein particle complex 10 3.59298
PRSS1 protease, serine, 1 (trypsin 1) 3.57213
CCDC85C coiled-coil domain containing 85C 3.56392
MYH10 myosin, heavy chain 10, non-muscle 3.55757
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 3.54892
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 3.54288
PNMA8A PNMA family member 8A 3.54012
SH2B1 SH2B adaptor protein 1 3.52468
PPCDC phosphopantothenoylcysteine decarboxylase 3.52329
ZNF208 zinc finger protein 208 3.52296
RRH retinal pigment epithelium-derived rhodopsin homolog 3.52063
ATG10 autophagy related 10 3.52051
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 3.51521
UBE2G1 ubiquitin-conjugating enzyme E2G 1 3.50404
HABP2 hyaluronan binding protein 2 3.49616
NOX4 NADPH oxidase 4 3.47554
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.46694
XPO4 exportin 4 3.46238
PELI2 pellino E3 ubiquitin protein ligase family member 2 3.43373
H2BC12 H2B clustered histone 12 3.43038
FAM76A family with sequence similarity 76, member A 3.42893
HTT huntingtin 3.42561
DROSHA drosha, ribonuclease type III 3.42343
RETREG1 reticulophagy regulator 1 3.41902
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 3.4167
GPR50 G protein-coupled receptor 50 3.41105
MAVS mitochondrial antiviral signaling protein 3.4103
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.40935
NXN nucleoredoxin 3.40537
SH3BP1 SH3-domain binding protein 1 3.40472
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 3.3973
BEAN1 brain expressed, associated with NEDD4, 1 3.38399
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 3.38219
TTC39A tetratricopeptide repeat domain 39A 3.3802
NME3 NME/NM23 nucleoside diphosphate kinase 3 3.37366
ZNF85 zinc finger protein 85 3.36906
RBM4 RNA binding motif protein 4 3.36406
XKR8 XK, Kell blood group complex subunit-related family, member 8 3.36254
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.35941
TMEM183A transmembrane protein 183A 3.35439
HAL histidine ammonia-lyase 3.35222
FAM136A family with sequence similarity 136, member A 3.34384
SCNN1G sodium channel, non voltage gated 1 gamma subunit 3.34287
SELPLG selectin P ligand 3.3384
GP1BA glycoprotein Ib (platelet), alpha polypeptide 3.33795
TOR3A torsin family 3, member A 3.33775
SH3GL1 SH3-domain GRB2-like 1 3.33104
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 3.33077
MTERF4 mitochondrial transcription termination factor 4 3.32468
GPRC5B G protein-coupled receptor, class C, group 5, member B 3.32055
C2CD3 C2 calcium-dependent domain containing 3 3.31766
DENND1C DENN/MADD domain containing 1C 3.3155
EBLN2 endogenous Bornavirus-like nucleoprotein 2 3.31456
NSFL1C NSFL1 (p97) cofactor (p47) 3.31202
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 3.31102
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 3.30743
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 3.30644
PNMA2 paraneoplastic Ma antigen 2 3.29507
WRN Werner syndrome, RecQ helicase-like 3.29124
DNM2 dynamin 2 3.28953
HOXA10 homeobox A10 3.28805
CLCN7 chloride channel, voltage-sensitive 7 3.28622
CCR6 chemokine (C-C motif) receptor 6 3.2745
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 3.27243
BCL2A1 BCL2-related protein A1 3.25161
PDE3A phosphodiesterase 3A, cGMP-inhibited 3.24893
TTLL12 tubulin tyrosine ligase-like family member 12 3.24753
MRPL44 mitochondrial ribosomal protein L44 3.24471
CFAP410 cilia and flagella associated protein 410 3.24451
CRYAA crystallin, alpha A 3.24121
YOD1 YOD1 deubiquitinase 3.23627
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 3.23053
FCHSD2 FCH and double SH3 domains 2 3.22515
YY1AP1 YY1 associated protein 1 3.22031
PROM1 prominin 1 3.21928
LRRC17 leucine rich repeat containing 17 3.20789
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.19668
CXCL5 chemokine (C-X-C motif) ligand 5 3.18451
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 3.18192
MRTFA myocardin related transcription factor A 3.17767
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 3.1694
HJURP Holliday junction recognition protein 3.16833
SBF1 SET binding factor 1 3.16599
MOGAT2 monoacylglycerol O-acyltransferase 2 3.16448
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 3.15157
SYNJ1 synaptojanin 1 3.1478
STX18 syntaxin 18 3.1441
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 3.14169
SLC12A9 solute carrier family 12, member 9 3.13961
CIC capicua transcriptional repressor 3.13301
LMNA lamin A/C 3.13227
RBM28 RNA binding motif protein 28 3.13167
STRN striatin, calmodulin binding protein 3.13147
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 3.12866
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 3.12758
RAI14 retinoic acid induced 14 3.12732
TBXT T-box transcription factor T 3.12725
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 3.11068
IL37 interleukin 37 3.1106
BMAL1 basic helix-loop-helix ARNT like 1 3.10471
ARID5A AT rich interactive domain 5A (MRF1-like) 3.10409
CCNK cyclin K 3.10169
DOK2 docking protein 2, 56kDa 3.10135
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 3.09953
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 3.09852
EML2 echinoderm microtubule associated protein like 2 3.09728
AAMP angio-associated, migratory cell protein 3.09331
PLXDC1 plexin domain containing 1 3.0925
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 3.08757
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 3.08609
TPX2 TPX2, microtubule-associated 3.07718
HCLS1 hematopoietic cell-specific Lyn substrate 1 3.07507
DDT D-dopachrome tautomerase 3.0714
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 3.06743
ZNF512B zinc finger protein 512B 3.06408
GLI3 GLI family zinc finger 3 3.06382
ITM2C integral membrane protein 2C 3.05973
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 3.05855
PLXNB2 plexin B2 3.05835
CSNK1G2 casein kinase 1, gamma 2 3.05645
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 3.05604
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 3.05525
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 3.05337
THUMPD2 THUMP domain containing 2 3.05265
GIPC2 GIPC PDZ domain containing family, member 2 3.05211
AMPD2 adenosine monophosphate deaminase 2 3.05204
PAPOLA poly(A) polymerase alpha 3.05022
TBC1D31 TBC1 domain family, member 31 3.05001
GPR137 G protein-coupled receptor 137 3.04867
GMCL1 germ cell-less, spermatogenesis associated 1 3.04711
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 3.0464
SH3YL1 SH3 and SYLF domain containing 1 3.04579
CELA3B chymotrypsin-like elastase family, member 3B 3.0456
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.04557
ALPL alkaline phosphatase, liver/bone/kidney 3.04457
DPF3 D4, zinc and double PHD fingers, family 3 3.04454
COX7B cytochrome c oxidase subunit VIIb 3.04323
FXR2 fragile X mental retardation, autosomal homolog 2 3.04067
INPP5K inositol polyphosphate-5-phosphatase K 3.04058
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 3.04014
GADD45B growth arrest and DNA-damage-inducible, beta 3.03891
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 3.03881
POLR1D polymerase (RNA) I polypeptide D, 16kDa 3.03671
PLCB4 phospholipase C, beta 4 3.03248
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 3.02701
POMZP3 POM121 and ZP3 fusion 3.02534
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 3.02418
TRIM62 tripartite motif containing 62 3.02134
MAP7D3 MAP7 domain containing 3 3.02034
SREK1 splicing regulatory glutamine/lysine-rich protein 1 3.0177
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.00878
CLDN18 claudin 18 3.00786
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 3.00742
GNA12 guanine nucleotide binding protein (G protein) alpha 12 3.00426
TSC2 tuberous sclerosis 2 3.00269
COQ8A coenzyme Q8A 3.00217
BRPF1 bromodomain and PHD finger containing, 1 3.00103
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 3.00016

decreased expression

Symbol Name Standardized Value
YME1L1 YME1-like 1 ATPase -15.5066
PGAM1 phosphoglycerate mutase 1 (brain) -14.979
RNMT RNA (guanine-7-) methyltransferase -11.4875
WAC WW domain containing adaptor with coiled-coil -8.67109
GTPBP4 GTP binding protein 4 -8.2447
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -7.33188
ANKRD26 ankyrin repeat domain 26 -7.09077
MTPAP mitochondrial poly(A) polymerase -7.04786
ZNF248 zinc finger protein 248 -6.88861
CDC123 cell division cycle 123 -6.55132
ABI1 abl-interactor 1 -6.50029
TMEM47 transmembrane protein 47 -6.49045
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -6.14216
NR4A2 nuclear receptor subfamily 4, group A, member 2 -6.11513
GDI2 GDP dissociation inhibitor 2 -5.86588
CEP192 centrosomal protein 192kDa -5.8347
MPPE1 metallophosphoesterase 1 -5.83072
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -5.77159
MMP12 matrix metallopeptidase 12 -5.75791
PAGE4 P antigen family, member 4 (prostate associated) -5.73222
KIF5B kinesin family member 5B -5.6542
SEH1L SEH1-like (S. cerevisiae) -5.39451
RALBP1 ralA binding protein 1 -5.31724
BACE2 beta-site APP-cleaving enzyme 2 -5.23163
RABGAP1 RAB GTPase activating protein 1 -5.15107
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -5.12455
PREB prolactin regulatory element binding -4.96111
IFRD2 interferon-related developmental regulator 2 -4.91521
EXOSC7 exosome component 7 -4.88507
PDCD2 programmed cell death 2 -4.83939
ZFPM2 zinc finger protein, FOG family member 2 -4.78529
TEAD3 TEA domain family member 3 -4.74434
METAP1 methionyl aminopeptidase 1 -4.74249
MTREX Mtr4 exosome RNA helicase -4.7404
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -4.72024
FAM50B family with sequence similarity 50, member B -4.69046
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -4.6382
CEP76 centrosomal protein 76kDa -4.58349
ALPI alkaline phosphatase, intestinal -4.57351
CHMP1B charged multivesicular body protein 1B -4.5326
GDF9 growth differentiation factor 9 -4.51763
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -4.51717
TWSG1 twisted gastrulation BMP signaling modulator 1 -4.49867
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -4.46683
NME1 NME/NM23 nucleoside diphosphate kinase 1 -4.43884
SAR1A secretion associated, Ras related GTPase 1A -4.42917
MYH11 myosin, heavy chain 11, smooth muscle -4.4253
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -4.4188
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -4.40581
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -4.40447
AMH anti-Mullerian hormone -4.36995
ARHGAP12 Rho GTPase activating protein 12 -4.35163
YES1 YES proto-oncogene 1, Src family tyrosine kinase -4.34951
MSRB2 methionine sulfoxide reductase B2 -4.34072
UGDH UDP-glucose 6-dehydrogenase -4.30901
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -4.30779
DMXL1 Dmx-like 1 -4.2987
CTSZ cathepsin Z -4.29739
PCP4 Purkinje cell protein 4 -4.26415
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -4.25971
MACROH2A2 macroH2A.2 histone -4.24905
SNX1 sorting nexin 1 -4.2381
COL4A5 collagen, type IV, alpha 5 -4.23316
SELENOP selenoprotein P -4.21069
PRRC2B proline-rich coiled-coil 2B -4.18996
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -4.18748
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 -4.18048
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -4.17999
DES desmin -4.17537
MFAP1 microfibrillar-associated protein 1 -4.17489
CUEDC2 CUE domain containing 2 -4.15943
CUL2 cullin 2 -4.14896
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -4.14168
ZNF274 zinc finger protein 274 -4.12124
SPAG11B sperm associated antigen 11B -4.1119
MPZL2 myelin protein zero-like 2 -4.08934
CAMK1G calcium/calmodulin-dependent protein kinase IG -4.07498
NDN necdin, melanoma antigen (MAGE) family member -4.07276
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -4.07148
EDDM3B epididymal protein 3B -4.06868
SS18 synovial sarcoma translocation, chromosome 18 -4.04726
DIXDC1 DIX domain containing 1 -4.03843
BMI1 BMI1 proto-oncogene, polycomb ring finger -4.03288
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -4.02428
HMGB3 high mobility group box 3 -4.01719
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -4.00035
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -3.99055
TIAM1 T-cell lymphoma invasion and metastasis 1 -3.98933
SGMS1 sphingomyelin synthase 1 -3.96923
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -3.96667
HDGF hepatoma-derived growth factor -3.95194
LTBP1 latent transforming growth factor beta binding protein 1 -3.94732
NPTN neuroplastin -3.93059
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 -3.92684
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -3.89011
ZNF532 zinc finger protein 532 -3.87975
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -3.87736
METTL4 methyltransferase like 4 -3.8763
CNTNAP2 contactin associated protein-like 2 -3.87384
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -3.87193
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -3.86862
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -3.86802
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -3.85682
CD1E CD1e molecule -3.85445
PGK1 phosphoglycerate kinase 1 -3.85026
MYL12B myosin, light chain 12B, regulatory -3.83997
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -3.83713
GHITM growth hormone inducible transmembrane protein -3.81722
LCMT2 leucine carboxyl methyltransferase 2 -3.80394
BMP7 bone morphogenetic protein 7 -3.79788
CHD9 chromodomain helicase DNA binding protein 9 -3.78212
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.78078
TMEM87A transmembrane protein 87A -3.7805
TGS1 trimethylguanosine synthase 1 -3.77294
TCTN3 tectonic family member 3 -3.76454
TAGLN transgelin -3.75895
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -3.74423
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -3.74198
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -3.74164
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -3.7363
RAN RAN, member RAS oncogene family -3.73571
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -3.73107
CDC5L cell division cycle 5-like -3.72497
MTTP microsomal triglyceride transfer protein -3.72378
PRKCB protein kinase C, beta -3.71327
ETNPPL ethanolamine-phosphate phospho-lyase -3.70996
ZNF22 zinc finger protein 22 -3.70767
EGR3 early growth response 3 -3.70733
HBE1 hemoglobin, epsilon 1 -3.69206
TPM2 tropomyosin 2 (beta) -3.68899
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -3.68512
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -3.67587
PEX5 peroxisomal biogenesis factor 5 -3.67321
RAB11FIP2 RAB11 family interacting protein 2 (class I) -3.66984
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -3.64259
GSTT1 glutathione S-transferase theta 1 -3.63563
STRAP serine/threonine kinase receptor associated protein -3.61114
CREB3 cAMP responsive element binding protein 3 -3.60938
TCP11L1 t-complex 11, testis-specific-like 1 -3.59197
TM2D3 TM2 domain containing 3 -3.57686
OAZ3 ornithine decarboxylase antizyme 3 -3.57345
GMEB1 glucocorticoid modulatory element binding protein 1 -3.56572
WDR37 WD repeat domain 37 -3.56379
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -3.56179
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.56116
MBL1P mannose-binding lectin (protein A) 1, pseudogene -3.55428
SEPHS1 selenophosphate synthetase 1 -3.54797
PFKP phosphofructokinase, platelet -3.54335
PCYOX1 prenylcysteine oxidase 1 -3.54309
SEC14L2 SEC14-like 2 (S. cerevisiae) -3.53745
AFG3L2 AFG3-like AAA ATPase 2 -3.53652
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -3.53514
PCDHB12 protocadherin beta 12 -3.52693
CNBP CCHC-type zinc finger, nucleic acid binding protein -3.52379
ADCY2 adenylate cyclase 2 (brain) -3.49956
FCRL2 Fc receptor-like 2 -3.49922
HRK harakiri, BCL2 interacting protein -3.49049
CRISP1 cysteine-rich secretory protein 1 -3.48807
THNSL1 threonine synthase-like 1 (S. cerevisiae) -3.4852
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -3.46355
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -3.4621
PITRM1 pitrilysin metallopeptidase 1 -3.45722
TUBB2A tubulin, beta 2A class IIa -3.45655
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 -3.45621
GPKOW G patch domain and KOW motifs -3.45442
TMED2 transmembrane emp24 domain trafficking protein 2 -3.45268
STK3 serine/threonine kinase 3 -3.45082
ATOSB atos homolog B -3.45042
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -3.44596
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -3.44004
LEMD3 LEM domain containing 3 -3.43075
VEZF1 vascular endothelial zinc finger 1 -3.43053
NOVA2 neuro-oncological ventral antigen 2 -3.42613
ARMC1 armadillo repeat containing 1 -3.41976
ACTC1 actin, alpha, cardiac muscle 1 -3.41447
DEDD death effector domain containing -3.41277
ZNF23 zinc finger protein 23 -3.41192
ZNF189 zinc finger protein 189 -3.40964
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -3.39616
EIF6 eukaryotic translation initiation factor 6 -3.3866
MMP19 matrix metallopeptidase 19 -3.38133
KIN Kin17 DNA and RNA binding protein -3.37466
CARD14 caspase recruitment domain family, member 14 -3.37392
RAB40A RAB40A, member RAS oncogene family -3.37347
TMEM62 transmembrane protein 62 -3.37318
LDAH lipid droplet associated hydrolase -3.37256
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -3.36543
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -3.36398
ZNF778 zinc finger protein 778 -3.35702
SIK3 SIK family kinase 3 -3.35422
MDRV muscular dystrophy, with rimmed vacuoles -3.34963
MEF2C myocyte enhancer factor 2C -3.3487
EMC7 ER membrane protein complex subunit 7 -3.34419
TPI1 triosephosphate isomerase 1 -3.34333
SPATA5L1 spermatogenesis associated 5-like 1 -3.33845
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -3.33707
LMOD1 leiomodin 1 (smooth muscle) -3.33557
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -3.33356
FGR FGR proto-oncogene, Src family tyrosine kinase -3.33317
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -3.33239
NCBP2 nuclear cap binding protein subunit 2, 20kDa -3.33182
ZFHX2 zinc finger homeobox 2 -3.32667
NCR3 natural cytotoxicity triggering receptor 3 -3.32594
GPR87 G protein-coupled receptor 87 -3.32104
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -3.31962
GPR37L1 G protein-coupled receptor 37 like 1 -3.31656
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) -3.31636
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -3.31481
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -3.31327
TMEM187 transmembrane protein 187 -3.30347
SPG11 spastic paraplegia 11 (autosomal recessive) -3.3021
ACTG2 actin, gamma 2, smooth muscle, enteric -3.30085
IFNG interferon, gamma -3.29799
AMOTL2 angiomotin like 2 -3.2891
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -3.28814
ST14 suppression of tumorigenicity 14 (colon carcinoma) -3.28625
ELSPBP1 epididymal sperm binding protein 1 -3.285
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -3.28365
CRYBG2 crystallin beta-gamma domain containing 2 -3.27602
EIF3I eukaryotic translation initiation factor 3, subunit I -3.27541
TM9SF3 transmembrane 9 superfamily member 3 -3.27236
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -3.27008
TH tyrosine hydroxylase -3.2675
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -3.26544
ZBTB5 zinc finger and BTB domain containing 5 -3.26265
TASOR transcription activation suppressor -3.26199
FABP6 fatty acid binding protein 6, ileal -3.26167
TPSD1 tryptase delta 1 -3.25684
COL4A6 collagen, type IV, alpha 6 -3.25056
JCAD junctional cadherin 5 associated -3.24781
FAM13B family with sequence similarity 13, member B -3.24107
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.23836
BEX4 brain expressed, X-linked 4 -3.23742
STEAP1B STEAP family member 1B -3.23504
CCSER2 coiled-coil serine-rich protein 2 -3.2348
DEFA5 defensin, alpha 5, Paneth cell-specific -3.23367
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -3.22993
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -3.22939
TSPAN1 tetraspanin 1 -3.22921
ACADL acyl-CoA dehydrogenase, long chain -3.2234
APOA1 apolipoprotein A-I -3.22075
GPM6A glycoprotein M6A -3.21161
INSIG2 insulin induced gene 2 -3.21077
CNN1 calponin 1, basic, smooth muscle -3.20145
CHM choroideremia (Rab escort protein 1) -3.20066
H2AZ1 H2A.Z variant histone 1 -3.19587
RNF4 ring finger protein 4 -3.19526
HPR haptoglobin-related protein -3.19237
TUBGCP4 tubulin, gamma complex associated protein 4 -3.19179
BYSL bystin-like -3.18245
GAS1 growth arrest-specific 1 -3.18092
CLTA clathrin, light chain A -3.17922
HPRT1 hypoxanthine phosphoribosyltransferase 1 -3.17111
CEP55 centrosomal protein 55kDa -3.16797
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -3.16537
IL2 interleukin 2 -3.16412
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -3.1583
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -3.15797
TPD52L1 tumor protein D52-like 1 -3.14751
ENO1 enolase 1, (alpha) -3.13725
FEM1B fem-1 homolog b (C. elegans) -3.13432
ANGPTL4 angiopoietin-like 4 -3.12684
NCOA3 nuclear receptor coactivator 3 -3.12683
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) -3.12192
PROP1 PROP paired-like homeobox 1 -3.11863
FAM169A family with sequence similarity 169, member A -3.11339
PRPF18 pre-mRNA processing factor 18 -3.11322
PLSCR2 phospholipid scramblase 2 -3.10158
PGAP1 post-GPI attachment to proteins 1 -3.08883
TRAPPC13 trafficking protein particle complex 13 -3.08259
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -3.08227
BZW1 basic leucine zipper and W2 domains 1 -3.07954
PSG5 pregnancy specific beta-1-glycoprotein 5 -3.07126
PKP1 plakophilin 1 -3.06771
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -3.05404
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -3.05339
MOB1A MOB kinase activator 1A -3.0511
TSPAN5 tetraspanin 5 -3.04984
SRPK3 SRSF protein kinase 3 -3.04823
NR2F1 nuclear receptor subfamily 2, group F, member 1 -3.0381
S1PR2 sphingosine-1-phosphate receptor 2 -3.03238
WFDC8 WAP four-disulfide core domain 8 -3.03214
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -3.03072
SERINC5 serine incorporator 5 -3.02969
TWNK twinkle mtDNA helicase -3.02872
SAGE1 sarcoma antigen 1 -3.0276
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -3.0264
MXI1 MAX interactor 1, dimerization protein -3.02464
EDDM3A epididymal protein 3A -3.02263
ADIRF adipogenesis regulatory factor -3.02198
CCN5 cellular communication network factor 5 -3.0186
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -3.01371
CD1B CD1b molecule -3.01259
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) -3.01147
ELOC elongin C -3.0077
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 -3.00744
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -3.0073
ITGA8 integrin, alpha 8 -3.00248