| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LJI308 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LJI308_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.237257 |
| AHNAK | AHNAK nucleoprotein | 0.161878 |
| FAT1 | FAT atypical cadherin 1 | 0.139634 |
| RPS12 | ribosomal protein S12 | 0.129727 |
| LDHA | lactate dehydrogenase A | 0.124204 |
| EXT1 | exostosin glycosyltransferase 1 | 0.111783 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.100484 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0969077 |
| CALR | calreticulin | 0.0875025 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0860475 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0821829 |
| MYO1E | myosin IE | 0.0795847 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0765082 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.07556 |
| FTL | ferritin, light polypeptide | 0.0736236 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.071415 |
| ASPH | aspartate beta-hydroxylase | 0.0704983 |
| LMO7 | LIM domain 7 | 0.0703683 |
| RPS8 | ribosomal protein S8 | 0.0703348 |
| RPS3 | ribosomal protein S3 | 0.0688591 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0660785 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0657657 |
| VCL | vinculin | 0.0610384 |
| RPL37A | ribosomal protein L37a | 0.0609634 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0591946 |
| MUC13 | mucin 13, cell surface associated | 0.0571861 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0537559 |
| EGFR | epidermal growth factor receptor | 0.052518 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0518456 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.051585 |
| RPL4 | ribosomal protein L4 | 0.0505946 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0502316 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0500738 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0500261 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0479705 |
| ENO1 | enolase 1, (alpha) | 0.0468556 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0468543 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0435966 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0435062 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0431084 |
| RPS27A | ribosomal protein S27a | 0.0424356 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0422357 |
| RPL26 | ribosomal protein L26 | 0.0421372 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0419186 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0418726 |
| INTS6 | integrator complex subunit 6 | 0.0416869 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0413494 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0413428 |
| NEBL | nebulette | 0.0410411 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0388518 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0385117 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0383805 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0381324 |
| RPL31 | ribosomal protein L31 | 0.0375859 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0370378 |
| MYO5B | myosin VB | 0.0365064 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0355237 |
| MT2A | metallothionein 2A | 0.0353473 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.035184 |
| CANX | calnexin | 0.035183 |
| TJP1 | tight junction protein 1 | 0.0351308 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0350913 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.035067 |
| RPL9 | ribosomal protein L9 | 0.0350238 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0349755 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0349011 |
| ATXN1 | ataxin 1 | 0.0346968 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0345449 |
| TPM4 | tropomyosin 4 | 0.0343495 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.034282 |
| PGK1 | phosphoglycerate kinase 1 | 0.0336436 |
| SMYD3 | SET and MYND domain containing 3 | 0.0334822 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0334103 |
| POF1B | premature ovarian failure, 1B | 0.0333497 |
| PCBP2 | poly(rC) binding protein 2 | 0.0332776 |
| FHIT | fragile histidine triad | 0.032922 |
| RPL7 | ribosomal protein L7 | 0.0323871 |
| FBXO11 | F-box protein 11 | 0.0322577 |
| RPL7A | ribosomal protein L7a | 0.0320886 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0319603 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0319319 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0316898 |
| SVIL | supervillin | 0.0316073 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0315019 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0311081 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311019 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0310086 |
| RPL27 | ribosomal protein L27 | 0.0308817 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0306655 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0305794 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0304331 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0303796 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0303793 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0300727 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0298899 |
| SQSTM1 | sequestosome 1 | 0.0297386 |
| RPS27 | ribosomal protein S27 | 0.0296385 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0295527 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0294199 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0292144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.193245 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17429 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.115663 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0708027 |
| TNS4 | tensin 4 | -0.0688679 |
| TMSB10 | thymosin beta 10 | -0.0653023 |
| NPSR1 | neuropeptide S receptor 1 | -0.0604672 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.057254 |
| S100A6 | S100 calcium binding protein A6 | -0.0552021 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0504033 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0461425 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0460292 |
| RPL34 | ribosomal protein L34 | -0.0447127 |
| GOLGA4 | golgin A4 | -0.0442301 |
| HMGA1 | high mobility group AT-hook 1 | -0.0418652 |
| HMGB1 | high mobility group box 1 | -0.0378955 |
| PRSS3 | protease, serine, 3 | -0.0370582 |
| RNF43 | ring finger protein 43 | -0.0361695 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0339897 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0336291 |
| FERMT1 | fermitin family member 1 | -0.032995 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0323757 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0322319 |
| USP3 | ubiquitin specific peptidase 3 | -0.0313313 |
| RPL35A | ribosomal protein L35a | -0.0308741 |
| ANXA2 | annexin A2 | -0.0305552 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0305531 |
| MUC17 | mucin 17, cell surface associated | -0.0293212 |
| CALB1 | calbindin 1, 28kDa | -0.0284766 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0270792 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.026797 |
| H1-0 | H1.0 linker histone | -0.026457 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0263494 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0255599 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0254691 |
| KIF5B | kinesin family member 5B | -0.0254556 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0247996 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0243493 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0240045 |
| CBX3 | chromobox homolog 3 | -0.0239366 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239245 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0238786 |
| TXNIP | thioredoxin interacting protein | -0.0236855 |
| CCND1 | cyclin D1 | -0.0235473 |
| ITGB4 | integrin, beta 4 | -0.0233924 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0231918 |
| FOSL1 | FOS-like antigen 1 | -0.0231148 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0223035 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0222215 |
| TMEM123 | transmembrane protein 123 | -0.0221302 |
| CENPF | centromere protein F, 350/400kDa | -0.0216492 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0215865 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0215839 |
| WDR43 | WD repeat domain 43 | -0.021446 |
| ETNK1 | ethanolamine kinase 1 | -0.02144 |
| TXNRD1 | thioredoxin reductase 1 | -0.021403 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0213756 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0213339 |
| SETD5 | SET domain containing 5 | -0.0211887 |
| RREB1 | ras responsive element binding protein 1 | -0.0209308 |
| RFX7 | regulatory factor X, 7 | -0.0208496 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0205069 |
| ACTN4 | actinin, alpha 4 | -0.0204364 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0203746 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0199728 |
| POTEF | POTE ankyrin domain family, member F | -0.0199671 |
| DEK | DEK proto-oncogene | -0.0194977 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.019341 |
| MATR3 | matrin 3 | -0.0192899 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0192715 |
| CENPE | centromere protein E, 312kDa | -0.0191566 |
| MMP12 | matrix metallopeptidase 12 | -0.0191459 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0190845 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0186964 |
| NF1 | neurofibromin 1 | -0.0186423 |
| LBR | lamin B receptor | -0.0185484 |
| GPHN | gephyrin | -0.0184094 |
| EHF | ets homologous factor | -0.0183597 |
| ABHD17C | abhydrolase domain containing 17C | -0.0181332 |
| KLK10 | kallikrein-related peptidase 10 | -0.0180818 |
| ZFR | zinc finger RNA binding protein | -0.0180035 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0179655 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.017782 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0177541 |
| NRN1 | neuritin 1 | -0.0176589 |
| NOP58 | NOP58 ribonucleoprotein | -0.017587 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0174832 |
| WASF2 | WAS protein family, member 2 | -0.0173485 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0173377 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0172054 |
| MYL12B | myosin, light chain 12B, regulatory | -0.017056 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0170365 |
| THOC2 | THO complex 2 | -0.0169528 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0169251 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0167066 |
| ZNF292 | zinc finger protein 292 | -0.0167034 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0166268 |
| RPS15 | ribosomal protein S15 | -0.0166197 |
| DSG2 | desmoglein 2 | -0.016618 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0165377 |
