| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LJI308 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LJI308_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.23577 |
| AHNAK | AHNAK nucleoprotein | 0.0732132 |
| FTL | ferritin, light polypeptide | 0.0704876 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0700588 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0662155 |
| RPS12 | ribosomal protein S12 | 0.0633872 |
| TPM3 | tropomyosin 3 | 0.0609586 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0607226 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0604656 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0581592 |
| MCL1 | myeloid cell leukemia 1 | 0.0577443 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0548643 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0542591 |
| RPL4 | ribosomal protein L4 | 0.054177 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0529805 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0519074 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0513437 |
| CAVIN1 | caveolae associated protein 1 | 0.0507323 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0505371 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0504923 |
| ASPH | aspartate beta-hydroxylase | 0.0504622 |
| TPI1 | triosephosphate isomerase 1 | 0.0491755 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0488592 |
| GRAMD1B | GRAM domain containing 1B | 0.0486576 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0476765 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0462079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0448995 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0441219 |
| LDHA | lactate dehydrogenase A | 0.043681 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0424149 |
| ENO1 | enolase 1, (alpha) | 0.0420998 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0416566 |
| RPS3 | ribosomal protein S3 | 0.0415975 |
| FLNB | filamin B, beta | 0.0413099 |
| APP | amyloid beta (A4) precursor protein | 0.041201 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0403906 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0402113 |
| CALR | calreticulin | 0.0401283 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0394734 |
| KIF5B | kinesin family member 5B | 0.039173 |
| SFTPA2 | surfactant protein A2 | 0.0390171 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0386943 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0368428 |
| ACTN1 | actinin, alpha 1 | 0.0363234 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0356896 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0356521 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0356009 |
| FMNL2 | formin-like 2 | 0.035476 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0354245 |
| NEGR1 | neuronal growth regulator 1 | 0.034425 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0342402 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0329753 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0328577 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0325942 |
| MYOF | myoferlin | 0.0323981 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0318997 |
| S100A6 | S100 calcium binding protein A6 | 0.0318289 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0314934 |
| ACTG1 | actin gamma 1 | 0.0312952 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0312461 |
| RACK1 | receptor for activated C kinase 1 | 0.0309237 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0308161 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0307086 |
| TPM4 | tropomyosin 4 | 0.0303979 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0301539 |
| DST | dystonin | 0.0297883 |
| RPL37A | ribosomal protein L37a | 0.029757 |
| CCPG1 | cell cycle progression 1 | 0.029543 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0294511 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0294125 |
| PTMA | prothymosin, alpha | 0.0292924 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0287523 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0284542 |
| STC1 | stanniocalcin 1 | 0.028341 |
| JUN | jun proto-oncogene | 0.028185 |
| PGK1 | phosphoglycerate kinase 1 | 0.0280481 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0279228 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0271731 |
| LMNA | lamin A/C | 0.0271718 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0270456 |
| RPL3 | ribosomal protein L3 | 0.0270397 |
| TPD52 | tumor protein D52 | 0.0268509 |
| ANGPTL4 | angiopoietin-like 4 | 0.0266325 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0264376 |
| SQSTM1 | sequestosome 1 | 0.0263136 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0260874 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0260784 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0260695 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0260116 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0257124 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0251105 |
| RPL26 | ribosomal protein L26 | 0.0250675 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250126 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0249961 |
| RPL23 | ribosomal protein L23 | 0.0245957 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0245557 |
| RPL7 | ribosomal protein L7 | 0.0242001 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0241685 |
| RPL12 | ribosomal protein L12 | 0.0239337 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0237941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.180279 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0634854 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0587012 |
| WDR43 | WD repeat domain 43 | -0.0436327 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0383646 |
| IGF2 | insulin-like growth factor 2 | -0.0367475 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0326223 |
| MT1X | metallothionein 1X | -0.0307234 |
| RPL35A | ribosomal protein L35a | -0.0293787 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0285508 |
| DENND4A | DENN/MADD domain containing 4A | -0.0242523 |
| RPS23 | ribosomal protein S23 | -0.0236569 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0217424 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0211303 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0206586 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0201096 |
| S100A10 | S100 calcium binding protein A10 | -0.0201003 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0198194 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.018599 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0180845 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0179662 |
| RPS15 | ribosomal protein S15 | -0.0177238 |
| ERBIN | erbb2 interacting protein | -0.0173681 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0173146 |
| MT1F | metallothionein 1F | -0.0165755 |
| TFG | TRK-fused gene | -0.0162261 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0161734 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0158921 |
| RCC1 | regulator of chromosome condensation 1 | -0.0156593 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0153093 |
| SMAD2 | SMAD family member 2 | -0.0147475 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0146539 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0145324 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0142755 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0141768 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0141555 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0140644 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0138627 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0130382 |
| NOP58 | NOP58 ribonucleoprotein | -0.0129 |
| NLK | nemo-like kinase | -0.0127854 |
| RPL34 | ribosomal protein L34 | -0.0127285 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0126727 |
| CCNL1 | cyclin L1 | -0.0124506 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0123734 |
| USP15 | ubiquitin specific peptidase 15 | -0.0122596 |
| RPS29 | ribosomal protein S29 | -0.0120156 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0120101 |
| DIDO1 | death inducer-obliterator 1 | -0.0118884 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -0.0118265 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0118096 |
| MAP7 | microtubule-associated protein 7 | -0.0116064 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0116051 |
| GLIS3 | GLIS family zinc finger 3 | -0.0115166 |
| RHOA | ras homolog family member A | -0.0114271 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0113442 |
| NUP58 | nucleoporin 58 | -0.0113383 |
| RPS5 | ribosomal protein S5 | -0.0110665 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0109397 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0109144 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0107336 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0106406 |
| PCNX4 | pecanex 4 | -0.0105596 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0105362 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0103439 |
| PAPOLA | poly(A) polymerase alpha | -0.0103181 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0103011 |
| INO80 | INO80 complex subunit | -0.0102157 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.0101067 |
| NRG1 | neuregulin 1 | -0.0100814 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.00998014 |
| CA2 | carbonic anhydrase II | -0.00990498 |
| RPS25 | ribosomal protein S25 | -0.00980456 |
| PFN1 | profilin 1 | -0.0097655 |
| YTHDC1 | YTH domain containing 1 | -0.00974008 |
| NAV3 | neuron navigator 3 | -0.00966223 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.00958603 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.00958267 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.00958096 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.00957712 |
| WBP11 | WW domain binding protein 11 | -0.00956008 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00954009 |
| TXNRD1 | thioredoxin reductase 1 | -0.00945677 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00939701 |
| ECT2 | epithelial cell transforming 2 | -0.00928146 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | -0.00921214 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.00885639 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.00883865 |
| RPL28 | ribosomal protein L28 | -0.00880189 |
| GPATCH2L | G patch domain containing 2-like | -0.00877462 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -0.00871023 |
| DYM | dymeclin | -0.00870257 |
| THOC2 | THO complex 2 | -0.00860227 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.00857815 |
| NEK10 | NIMA-related kinase 10 | -0.00856957 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.00848807 |
| YLPM1 | YLP motif containing 1 | -0.0084729 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.00842324 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.00836263 |
| COG5 | component of oligomeric golgi complex 5 | -0.00831511 |
