| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LJI308 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LJI308_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.107126 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102716 |
| PEG10 | paternally expressed 10 | 0.0737098 |
| VIM | vimentin | 0.0632883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0591733 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0587839 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0440823 |
| ENO1 | enolase 1, (alpha) | 0.0438838 |
| ACTG1 | actin gamma 1 | 0.0425889 |
| RPS12 | ribosomal protein S12 | 0.0400012 |
| PCBP2 | poly(rC) binding protein 2 | 0.0382091 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.037823 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0373 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0359356 |
| CANX | calnexin | 0.0352044 |
| TPR | translocated promoter region, nuclear basket protein | 0.0347954 |
| APP | amyloid beta (A4) precursor protein | 0.0347239 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0345622 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334415 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0332593 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0332023 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0331799 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0331219 |
| H1-0 | H1.0 linker histone | 0.0319623 |
| RPL4 | ribosomal protein L4 | 0.0318575 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0314562 |
| MED13L | mediator complex subunit 13-like | 0.0307232 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0294507 |
| CALR | calreticulin | 0.0293477 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0291828 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0286806 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0285734 |
| QKI | QKI, KH domain containing, RNA binding | 0.0283948 |
| AHNAK | AHNAK nucleoprotein | 0.0279984 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0279843 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0279766 |
| CLTC | clathrin, heavy chain (Hc) | 0.0277393 |
| YBX1 | Y box binding protein 1 | 0.0272816 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.027041 |
| CDK6 | cyclin-dependent kinase 6 | 0.026815 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0266291 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0266209 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0259879 |
| TMSB4X | thymosin beta 4, X-linked | 0.0257461 |
| IGF2 | insulin-like growth factor 2 | 0.0256171 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0254836 |
| COL5A2 | collagen, type V, alpha 2 | 0.0250144 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0246656 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.024617 |
| SET | SET nuclear proto-oncogene | 0.0243517 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0242339 |
| MT2A | metallothionein 2A | 0.0242267 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0241585 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0239765 |
| RYBP | RING1 and YY1 binding protein | 0.02365 |
| THBS1 | thrombospondin 1 | 0.0232376 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0230693 |
| XPO1 | exportin 1 | 0.0227687 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0222987 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0222173 |
| NRDC | nardilysin convertase | 0.0221672 |
| TXNRD1 | thioredoxin reductase 1 | 0.0218508 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0216993 |
| RPL3 | ribosomal protein L3 | 0.0215799 |
| PARD3 | par-3 family cell polarity regulator | 0.0215755 |
| PGK1 | phosphoglycerate kinase 1 | 0.0214658 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0213197 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0213112 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0213085 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0212965 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0212873 |
| NCKAP1 | NCK-associated protein 1 | 0.0209438 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0207579 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0206692 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0205845 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0204744 |
| CLIC4 | chloride intracellular channel 4 | 0.0203587 |
| TPM3 | tropomyosin 3 | 0.0203442 |
| MYOF | myoferlin | 0.0200407 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0200323 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0198089 |
| MATR3 | matrin 3 | 0.019805 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.019582 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.019472 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0194609 |
| PDS5B | PDS5 cohesin associated factor B | 0.0192763 |
| SETD5 | SET domain containing 5 | 0.0192669 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0191215 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0188382 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0187975 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.018793 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0187456 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0186766 |
| POTEF | POTE ankyrin domain family, member F | 0.0185764 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0185152 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0184785 |
| CALU | calumenin | 0.0182639 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0182488 |
| ABI2 | abl-interactor 2 | 0.0181534 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0180803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.112486 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.103464 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0762298 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0735651 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0637352 |
| PLPP1 | phospholipid phosphatase 1 | -0.0606163 |
| ITGAV | integrin, alpha V | -0.0581645 |
| SPAG9 | sperm associated antigen 9 | -0.0556554 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0540155 |
| CADM2 | cell adhesion molecule 2 | -0.0526778 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0524302 |
| TENM3 | teneurin transmembrane protein 3 | -0.0515669 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0500765 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0494748 |
| SRP54 | signal recognition particle 54kDa | -0.0486394 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0478541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0474111 |
| PTMA | prothymosin, alpha | -0.045914 |
| PHIP | pleckstrin homology domain interacting protein | -0.0452196 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0418624 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0414697 |
| NRG1 | neuregulin 1 | -0.040719 |
| RAD51B | RAD51 paralog B | -0.0395383 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0394181 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0383846 |
| TMSB10 | thymosin beta 10 | -0.0379917 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.037732 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0365611 |
| NTM | neurotrimin | -0.0364287 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0349105 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0347425 |
| LRRC4C | leucine rich repeat containing 4C | -0.034516 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0337355 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0336069 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0335192 |
| FOXP2 | forkhead box P2 | -0.0334277 |
| UPP1 | uridine phosphorylase 1 | -0.033227 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0329877 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0329474 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0324645 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0322965 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0319016 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0318549 |
| HDAC9 | histone deacetylase 9 | -0.0317315 |
| ANK2 | ankyrin 2, neuronal | -0.0308466 |
| RPS27A | ribosomal protein S27a | -0.030344 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0302853 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0302228 |
| RPL35A | ribosomal protein L35a | -0.0291597 |
| VMP1 | vacuole membrane protein 1 | -0.0282758 |
| CCDC138 | coiled-coil domain containing 138 | -0.027757 |
| RBM20 | RNA binding motif protein 20 | -0.0266452 |
| TENM2 | teneurin transmembrane protein 2 | -0.0263117 |
| GPATCH8 | G patch domain containing 8 | -0.0261439 |
| THOC2 | THO complex 2 | -0.025177 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0241879 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0240068 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0238038 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0231458 |
| PDGFC | platelet derived growth factor C | -0.0228769 |
| RSF1 | remodeling and spacing factor 1 | -0.022863 |
| NHSL1 | NHS-like 1 | -0.0223607 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0219286 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0218535 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0217743 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0217392 |
| ZNF385D | zinc finger protein 385D | -0.0217343 |
| ATXN2 | ataxin 2 | -0.0215107 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0213114 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0212149 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0210171 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0208726 |
| CDH19 | cadherin 19, type 2 | -0.020818 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0207976 |
| RPL36A | ribosomal protein L36a | -0.0207944 |
| PCDH7 | protocadherin 7 | -0.0206014 |
| HM13 | histocompatibility (minor) 13 | -0.0205172 |
| RPL37 | ribosomal protein L37 | -0.0203359 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0200899 |
| NXN | nucleoredoxin | -0.0199536 |
| GSE1 | Gse1 coiled-coil protein | -0.0199487 |
| RPS16 | ribosomal protein S16 | -0.0198637 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0198617 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0196043 |
| RPL8 | ribosomal protein L8 | -0.0196033 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0195465 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0195234 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0195231 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0194157 |
| CDK13 | cyclin-dependent kinase 13 | -0.0191134 |
| FOXO3 | forkhead box O3 | -0.0190938 |
| RPL31 | ribosomal protein L31 | -0.018993 |
| PGPEP1L | pyroglutamyl-peptidase I-like | -0.0189004 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.018858 |
| ASTN2 | astrotactin 2 | -0.0187764 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0186884 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0186765 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0185228 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0184996 |
| RPS8 | ribosomal protein S8 | -0.0184902 |
