| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LJI308 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LJI308_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.214034 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.11848 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0805469 |
| PRELID2 | PRELI domain containing 2 | 0.062808 |
| RPL4 | ribosomal protein L4 | 0.0618439 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0608212 |
| VCL | vinculin | 0.0605852 |
| LDHA | lactate dehydrogenase A | 0.058693 |
| PCBP2 | poly(rC) binding protein 2 | 0.0566634 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0530549 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0515344 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0506319 |
| APP | amyloid beta (A4) precursor protein | 0.0502175 |
| ENO1 | enolase 1, (alpha) | 0.049877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0481486 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0462351 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0452788 |
| PGK1 | phosphoglycerate kinase 1 | 0.0429525 |
| TJP1 | tight junction protein 1 | 0.0419114 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0409086 |
| RPS3 | ribosomal protein S3 | 0.0406964 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0404644 |
| RPS8 | ribosomal protein S8 | 0.0389983 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0382992 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377492 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0370597 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0368411 |
| HDAC9 | histone deacetylase 9 | 0.0366175 |
| RBM39 | RNA binding motif protein 39 | 0.0361049 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0360364 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0357169 |
| ZNF608 | zinc finger protein 608 | 0.0357008 |
| INTS6 | integrator complex subunit 6 | 0.0354222 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0347638 |
| IGF1R | insulin-like growth factor 1 receptor | 0.033211 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0327711 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0325611 |
| B2M | beta-2-microglobulin | 0.0323202 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0321748 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0318103 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.031792 |
| RPL3 | ribosomal protein L3 | 0.0317096 |
| PDGFC | platelet derived growth factor C | 0.0315491 |
| RACK1 | receptor for activated C kinase 1 | 0.0314259 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0313647 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0312707 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0312264 |
| EZR | ezrin | 0.0306479 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300001 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.029894 |
| ASPH | aspartate beta-hydroxylase | 0.0298939 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296778 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296581 |
| RPL23 | ribosomal protein L23 | 0.0293224 |
| RPLP0 | ribosomal protein, large, P0 | 0.0292152 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0290688 |
| RAD51B | RAD51 paralog B | 0.028678 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0283368 |
| CTBP2 | C-terminal binding protein 2 | 0.0281351 |
| CREBBP | CREB binding protein | 0.0281259 |
| VIM | vimentin | 0.0280626 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0280605 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0280188 |
| FTL | ferritin, light polypeptide | 0.0278897 |
| RNF213 | ring finger protein 213 | 0.0277991 |
| NAV2 | neuron navigator 2 | 0.0277845 |
| MSI2 | musashi RNA-binding protein 2 | 0.0274518 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0273506 |
| RPL26 | ribosomal protein L26 | 0.0271197 |
| NDRG1 | N-myc downstream regulated 1 | 0.0270871 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0270263 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0267935 |
| EGFR | epidermal growth factor receptor | 0.0266397 |
| CANX | calnexin | 0.0265079 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0263883 |
| SFTPA2 | surfactant protein A2 | 0.0263747 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0259372 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0258639 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0258376 |
| USP47 | ubiquitin specific peptidase 47 | 0.0254188 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0254035 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.02508 |
| SMYD3 | SET and MYND domain containing 3 | 0.0250262 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0249182 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0248313 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0247241 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0244952 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0244937 |
| FHIT | fragile histidine triad | 0.0244425 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0243479 |
| BRD2 | bromodomain containing 2 | 0.0242634 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.02421 |
| ZNF217 | zinc finger protein 217 | 0.0241678 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0241639 |
| ERBIN | erbb2 interacting protein | 0.0241106 |
| RPL31 | ribosomal protein L31 | 0.0240634 |
| RPL7 | ribosomal protein L7 | 0.0240489 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0237432 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237002 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0236917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23332 |
| PTMA | prothymosin, alpha | -0.117406 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0915632 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0835977 |
| CCND1 | cyclin D1 | -0.080747 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0725157 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0723793 |
| BMP10 | bone morphogenetic protein 10 | -0.0553569 |
| MKI67 | marker of proliferation Ki-67 | -0.0539174 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0444851 |
| EVI5 | ecotropic viral integration site 5 | -0.0434271 |
| RPL35A | ribosomal protein L35a | -0.0388668 |
| DPYD | dihydropyrimidine dehydrogenase | -0.037827 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0367928 |
| BMP2K | BMP2 inducible kinase | -0.0357936 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0345619 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0342694 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0325796 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0315334 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0307807 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0306886 |
| RPS6 | ribosomal protein S6 | -0.0306441 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0303492 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286627 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0284219 |
| DGKH | diacylglycerol kinase, eta | -0.0279969 |
| PFN1 | profilin 1 | -0.0273576 |
| RHOA | ras homolog family member A | -0.026258 |
| TMSB4X | thymosin beta 4, X-linked | -0.0261183 |
| TPM4 | tropomyosin 4 | -0.025986 |
| TXNIP | thioredoxin interacting protein | -0.0258478 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0256369 |
| RPL34 | ribosomal protein L34 | -0.0255183 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0253522 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0252915 |
| NBEA | neurobeachin | -0.024749 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0243511 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0242546 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.024056 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0236498 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0234916 |
| ONECUT2 | one cut homeobox 2 | -0.0234498 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0230746 |
| PLXNA2 | plexin A2 | -0.0227102 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0225764 |
| LOXL3 | lysyl oxidase-like 3 | -0.0224701 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0224327 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0221877 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0221481 |
| TOB1 | transducer of ERBB2, 1 | -0.0218573 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0216274 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0215711 |
| PKM | pyruvate kinase, muscle | -0.0215191 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0213446 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.020543 |
| TCF12 | transcription factor 12 | -0.0205082 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205017 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0201911 |
| ITGA10 | integrin, alpha 10 | -0.020141 |
| SEPTIN11 | septin 11 | -0.0198257 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0198174 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0191246 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0188792 |
| NMD3 | NMD3 ribosome export adaptor | -0.01886 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0187109 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.01857 |
| GPHN | gephyrin | -0.0185524 |
| HDGFL3 | HDGF like 3 | -0.0185192 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0184667 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0183818 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0183052 |
| ASTN2 | astrotactin 2 | -0.018219 |
| USP3 | ubiquitin specific peptidase 3 | -0.0181968 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0180138 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0179073 |
| KIF2A | kinesin heavy chain member 2A | -0.0175682 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0174342 |
| RPS23 | ribosomal protein S23 | -0.0173757 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0172831 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0172803 |
| DIAPH3 | diaphanous-related formin 3 | -0.0171789 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0170725 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0166427 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0164751 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0163948 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0163037 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0162379 |
| DUSP4 | dual specificity phosphatase 4 | -0.0161967 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0158556 |
| ACTG1 | actin gamma 1 | -0.0156718 |
| GOLGA4 | golgin A4 | -0.0156506 |
| S100A4 | S100 calcium binding protein A4 | -0.0154217 |
| EFL1 | elongation factor like GTPase 1 | -0.0151869 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0151821 |
| SHLD2 | shieldin complex subunit 2 | -0.0151653 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0151146 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0151011 |
| FMN1 | formin 1 | -0.014782 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0147047 |
| NEBL | nebulette | -0.0146243 |
