| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LJI308 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LJI308_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.172768 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.124687 |
| MT2A | metallothionein 2A | 0.116904 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.114256 |
| ASPH | aspartate beta-hydroxylase | 0.0916463 |
| SQSTM1 | sequestosome 1 | 0.0909199 |
| FTL | ferritin, light polypeptide | 0.0902871 |
| VIM | vimentin | 0.0902031 |
| PTMA | prothymosin, alpha | 0.0842813 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0831218 |
| B2M | beta-2-microglobulin | 0.0802954 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.07889 |
| HLA-B | major histocompatibility complex, class I, B | 0.0775111 |
| CANX | calnexin | 0.0724776 |
| SFTPA2 | surfactant protein A2 | 0.0693872 |
| FN1 | fibronectin 1 | 0.069105 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0682857 |
| ENO1 | enolase 1, (alpha) | 0.0674613 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0587272 |
| RPL26 | ribosomal protein L26 | 0.057175 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0552284 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0536805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0530501 |
| RACK1 | receptor for activated C kinase 1 | 0.0515923 |
| RPS12 | ribosomal protein S12 | 0.0513026 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0510353 |
| LMNA | lamin A/C | 0.0500418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0486492 |
| TPR | translocated promoter region, nuclear basket protein | 0.0475276 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0461051 |
| TMSB10 | thymosin beta 10 | 0.04529 |
| AHNAK | AHNAK nucleoprotein | 0.0446467 |
| RPS8 | ribosomal protein S8 | 0.0435501 |
| RPL31 | ribosomal protein L31 | 0.0434499 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0432388 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0431909 |
| S100A6 | S100 calcium binding protein A6 | 0.0424389 |
| NDRG1 | N-myc downstream regulated 1 | 0.0423635 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0418538 |
| ITGA1 | integrin, alpha 1 | 0.0418276 |
| S100A10 | S100 calcium binding protein A10 | 0.0413068 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0406993 |
| RPL37A | ribosomal protein L37a | 0.0405113 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0391156 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0383117 |
| RPL12 | ribosomal protein L12 | 0.037098 |
| RPS6 | ribosomal protein S6 | 0.0365427 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.036412 |
| RPS27 | ribosomal protein S27 | 0.0364082 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0356733 |
| TPI1 | triosephosphate isomerase 1 | 0.0355803 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0353113 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.035175 |
| RPS3 | ribosomal protein S3 | 0.0348245 |
| RPL37 | ribosomal protein L37 | 0.0348121 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0345807 |
| RPL35A | ribosomal protein L35a | 0.0345581 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0344073 |
| DUSP6 | dual specificity phosphatase 6 | 0.0337672 |
| RPS19 | ribosomal protein S19 | 0.0336998 |
| TMSB4X | thymosin beta 4, X-linked | 0.033492 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0332618 |
| PGK1 | phosphoglycerate kinase 1 | 0.0332178 |
| CALR | calreticulin | 0.0331353 |
| RPLP1 | ribosomal protein, large, P1 | 0.0329361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0325164 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0321998 |
| TMEM156 | transmembrane protein 156 | 0.032042 |
| RPS27A | ribosomal protein S27a | 0.0319672 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0316793 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0316558 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0314111 |
| RPL9 | ribosomal protein L9 | 0.0314037 |
| RPL11 | ribosomal protein L11 | 0.0312904 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0310199 |
| SMAD3 | SMAD family member 3 | 0.0309811 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0302749 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301003 |
| OSMR | oncostatin M receptor | 0.029964 |
| APP | amyloid beta (A4) precursor protein | 0.0298342 |
| RPS29 | ribosomal protein S29 | 0.0297557 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296889 |
| FAT1 | FAT atypical cadherin 1 | 0.0293582 |
| UBC | ubiquitin C | 0.029267 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0287597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0287528 |
| RPL23 | ribosomal protein L23 | 0.0285957 |
| LDHA | lactate dehydrogenase A | 0.0285832 |
| RPL36 | ribosomal protein L36 | 0.0285817 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0282726 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0282191 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0278719 |
| EREG | epiregulin | 0.027781 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0277414 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0275618 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0275444 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0272899 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.027157 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0267312 |
| HLA-A | major histocompatibility complex, class I, A | 0.0265933 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.0853011 |
| VCL | vinculin | -0.0389284 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0368884 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0219653 |
| EGR1 | early growth response 1 | -0.0191119 |
| AEBP2 | AE binding protein 2 | -0.01521 |
| POTEF | POTE ankyrin domain family, member F | -0.0139295 |
| VEGFA | vascular endothelial growth factor A | -0.0135378 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0133175 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0120914 |
| ATN1 | atrophin 1 | -0.0114657 |
| POU2F2 | POU class 2 homeobox 2 | -0.0107907 |
| TENM4 | teneurin transmembrane protein 4 | -0.010639 |
| RCOR1 | REST corepressor 1 | -0.0106277 |
| GPC6 | glypican 6 | -0.010438 |
| INTS6 | integrator complex subunit 6 | -0.00996407 |
| PALLD | palladin, cytoskeletal associated protein | -0.00995533 |
| TUFT1 | tuftelin 1 | -0.00877724 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.00841015 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.00830809 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00830515 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.00815726 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.00804798 |
| CADM1 | cell adhesion molecule 1 | -0.00800032 |
| PLSCR2 | phospholipid scramblase 2 | -0.00792593 |
| FRY | furry homolog (Drosophila) | -0.0078943 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00769438 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.00766244 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0075046 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0074902 |
| ARF4 | ADP-ribosylation factor 4 | -0.00743044 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 | -0.00738227 |
| LRRC23 | leucine rich repeat containing 23 | -0.00729218 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00726908 |
| PXDNL | peroxidasin-like | -0.00726675 |
| SUSD1 | sushi domain containing 1 | -0.00719388 |
| PLA2G12B | phospholipase A2, group XIIB | -0.0070989 |
| AGRN | agrin | -0.00708503 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.00702618 |
| WDR49 | WD repeat domain 49 | -0.0069379 |
| EXOSC3 | exosome component 3 | -0.00688913 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.00683352 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0065848 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00656715 |
| CCDC138 | coiled-coil domain containing 138 | -0.00639132 |
| NABP1 | nucleic acid binding protein 1 | -0.0062772 |
| FAM151B | family with sequence similarity 151, member B | -0.00626046 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00625318 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.00624242 |
| IGF2 | insulin-like growth factor 2 | -0.00621079 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | -0.00614096 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00606612 |
| HLA-G | major histocompatibility complex, class I, G | -0.00599712 |
| ADAM20 | ADAM metallopeptidase domain 20 | -0.00595416 |
| GLUL | glutamate-ammonia ligase | -0.00594909 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00591612 |
| HOMER1 | homer scaffolding protein 1 | -0.00591093 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.00590442 |
| DHFR | dihydrofolate reductase | -0.00587572 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00582617 |
| TLL2 | tolloid-like 2 | -0.00577047 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00564366 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.00562781 |
| GLCCI1 | glucocorticoid induced 1 | -0.00561567 |
| FGF14 | fibroblast growth factor 14 | -0.00558448 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.00557739 |
| NPAS1 | neuronal PAS domain protein 1 | -0.00553551 |
| DGKI | diacylglycerol kinase, iota | -0.00551402 |
| MROH1 | maestro heat-like repeat family member 1 | -0.00544997 |
| CCNL1 | cyclin L1 | -0.00543995 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 | -0.00542648 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00541672 |
| RSU1 | Ras suppressor protein 1 | -0.00538059 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00537983 |
| RNF44 | ring finger protein 44 | -0.00537583 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00536756 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00531875 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00531458 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.00526773 |
| POLN | polymerase (DNA directed) nu | -0.00525029 |
| MOB3B | MOB kinase activator 3B | -0.00524833 |
| MYOCOS | myocilin opposite strand | -0.00523794 |
| C5AR1 | complement component 5a receptor 1 | -0.00523022 |
| RUNX2 | runt-related transcription factor 2 | -0.00519582 |
| MNT | MAX network transcriptional repressor | -0.00511659 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.00510434 |
| CFAP70 | cilia and flagella associated protein 70 | -0.00509959 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | -0.00508026 |
| PGAM4 | phosphoglycerate mutase family member 4 | -0.00507858 |
| NLK | nemo-like kinase | -0.00505823 |
| TTYH3 | tweety family member 3 | -0.00505817 |
| WDR27 | WD repeat domain 27 | -0.00504903 |
| ZNF644 | zinc finger protein 644 | -0.00503316 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00501898 |
| GPATCH2L | G patch domain containing 2-like | -0.00501091 |
| CDKL4 | cyclin-dependent kinase-like 4 | -0.00499199 |
| BAG5 | BCL2-associated athanogene 5 | -0.00499129 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00498311 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.00494838 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00494258 |
