LLY-507 Gene Set
Genes
19 genes differentially expressed following the LLY-507 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
5.30663
|
|
INSIG1
|
insulin induced gene 1
|
4.84425
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
4.20939
|
|
ACAT2
|
acetyl-CoA acetyltransferase 2
|
3.98598
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.95489
|
|
FADS1
|
fatty acid desaturase 1
|
3.83134
|
|
FDPS
|
farnesyl diphosphate synthase
|
3.78341
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
3.7154
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
3.6726
|
|
MSMO1
|
methylsterol monooxygenase 1
|
3.59594
|
|
TBX2
|
T-box 2
|
3.42155
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
3.38622
|
|
SQLE
|
squalene epoxidase
|
3.30694
|
|
HSD17B7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
3.14308
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
3.09085
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
3.00933
|
|
ERG28
|
ergosterol biosynthesis 28 homolog
|
3.00861
|
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
3.00142
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
-4.15991
|
