LM-1685-207 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the LM-1685-207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADM adrenomedullin
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARR3 arrestin 3, retinal (X-arrestin)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B3GAT3 beta-1,3-glucuronyltransferase 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF76 chromosome 10 open reading frame 76
C1ORF61 chromosome 1 open reading frame 61
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC176 coiled-coil domain containing 176
CD2AP CD2-associated protein
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLDN15 claudin 15
CLIC4 chloride intracellular channel 4
COX5B cytochrome c oxidase subunit Vb
CSH2 chorionic somatomammotropin hormone 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYB561 cytochrome b561
DENND3 DENN/MADD domain containing 3
DSG3 desmoglein 3
DST dystonin
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ERCC1 excision repair cross-complementation group 1
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
FAM134B family with sequence similarity 134, member B
FOSL2 FOS-like antigen 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FXR2 fragile X mental retardation, autosomal homolog 2
GDF3 growth differentiation factor 3
GNAS GNAS complex locus
HIST1H2BD histone cluster 1, H2bd
HLA-DOA major histocompatibility complex, class II, DO alpha
HOMER3 homer scaffolding protein 3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IL13RA1 interleukin 13 receptor, alpha 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LINC00574 long intergenic non-protein coding RNA 574
LUZP1 leucine zipper protein 1
MARC2 mitochondrial amidoxime reducing component 2
MAST2 microtubule associated serine/threonine kinase 2
MBNL2 muscleblind-like splicing regulator 2
MIPEP mitochondrial intermediate peptidase
MPHOSPH9 M-phase phosphoprotein 9
MT1F metallothionein 1F
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYT1 myelin transcription factor 1
NHEJ1 nonhomologous end-joining factor 1
PARG poly (ADP-ribose) glycohydrolase
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PKNOX2 PBX/knotted 1 homeobox 2
PLEC plectin
PLXNB1 plexin B1
PRDM14 PR domain containing 14
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PVALB parvalbumin
QSER1 glutamine and serine rich 1
RABL3 RAB, member of RAS oncogene family-like 3
RALB v-ral simian leukemia viral oncogene homolog B
RBL2 retinoblastoma-like 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF121 ring finger protein 121
RPLP2 ribosomal protein, large, P2
RPUSD2 RNA pseudouridylate synthase domain containing 2
SGSM3 small G protein signaling modulator 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMYD5 SMYD family member 5
SNRPF small nuclear ribonucleoprotein polypeptide F
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STX12 syntaxin 12
TBX10 T-box 10
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TMEM161A transmembrane protein 161A
TMEM53 transmembrane protein 53
WDR41 WD repeat domain 41
WRAP53 WD repeat containing, antisense to TP53
ZMYM2 zinc finger, MYM-type 2
ZNF277 zinc finger protein 277
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ARHGAP10 Rho GTPase activating protein 10
ASIC4 acid sensing (proton gated) ion channel family member 4
ATAT1 alpha tubulin acetyltransferase 1
BDKRB2 bradykinin receptor B2
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
CCNJL cyclin J-like
CD34 CD34 molecule
CENPM centromere protein M
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTN1 contactin 1
CPN1 carboxypeptidase N, polypeptide 1
CRELD1 cysteine-rich with EGF-like domains 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
E4F1 E4F transcription factor 1
EPHB6 EPH receptor B6
EPX eosinophil peroxidase
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FGF16 fibroblast growth factor 16
GALR3 galanin receptor 3
GCKR glucokinase (hexokinase 4) regulator
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH3 G patch domain containing 3
GRIP2 glutamate receptor interacting protein 2
HHLA1 HERV-H LTR-associating 1
HIST1H3J histone cluster 1, H3j
HSF2BP heat shock transcription factor 2 binding protein
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL15RA interleukin 15 receptor, alpha
IL22RA1 interleukin 22 receptor, alpha 1
IL2RG interleukin 2 receptor, gamma
INE1 inactivation escape 1 (non-protein coding)
INO80D INO80 complex subunit D
JOSD1 Josephin domain containing 1
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM7A lysine (K)-specific demethylase 7A
KRT13 keratin 13, type I
LMTK1 lemur tail kinase 1
LRRC37A3 leucine rich repeat containing 37, member A3
MAST3 microtubule associated serine/threonine kinase 3
MCM9 minichromosome maintenance complex component 9
MLN motilin
MON1B MON1 secretory trafficking family member B
MT4 metallothionein 4
NISCH nischarin
NKX2-5 NK2 homeobox 5
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5C 5', 3'-nucleotidase, cytosolic
NTNG1 netrin G1
OCEL1 occludin/ELL domain containing 1
PAX1 paired box 1
PDZD7 PDZ domain containing 7
PEX12 peroxisomal biogenesis factor 12
PIPOX pipecolic acid oxidase
PLEK2 pleckstrin 2
PRKCE protein kinase C, epsilon
PRMT3 protein arginine methyltransferase 3
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RECQL4 RecQ protein-like 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RINT1 RAD50 interactor 1
RND1 Rho family GTPase 1
RNF141 ring finger protein 141
RNF39 ring finger protein 39
RPAP2 RNA polymerase II associated protein 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC41A3 solute carrier family 41, member 3
SNX10 sorting nexin 10
SOD3 superoxide dismutase 3, extracellular
SPTBN5 spectrin, beta, non-erythrocytic 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TG thyroglobulin
TGM5 transglutaminase 5
TLN1 talin 1
TPSD1 tryptase delta 1
TRAC T cell receptor alpha constant
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUBA3D tubulin, alpha 3d
WNT10B wingless-type MMTV integration site family, member 10B
ZNF189 zinc finger protein 189
ZNF562 zinc finger protein 562
ZNF586 zinc finger protein 586