LMBR1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description limb development membrane protein 1|This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 64327)
External Link https://ncbi.nlm.nih.gov/gene/64327
Similar Terms
Downloads & Tools

Genes

498 genes differentially expressed following the LMBR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.0153832
NUSAP1 nucleolar and spindle associated protein 1 0.0148817
SSBP2 single-stranded DNA binding protein 2 0.0148319
PRPF4 pre-mRNA processing factor 4 0.0139944
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0129217
OLFM1 olfactomedin 1 0.0128851
CCNF cyclin F 0.0121876
MCM5 minichromosome maintenance complex component 5 0.0117881
FOXM1 forkhead box M1 0.0112012
KIF20A kinesin family member 20A 0.0110224
CIT citron rho-interacting serine/threonine kinase 0.0109556
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0106169
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0104758
INSIG1 insulin induced gene 1 0.0103178
ANPEP alanyl (membrane) aminopeptidase 0.0102672
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.0102302
PDZK1 PDZ domain containing 1 0.0102239
PRDX2 peroxiredoxin 2 0.0101911
FASN fatty acid synthase 0.0101565
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.0101382
HOXC10 homeobox C10 0.0101109
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.0100739
RAPSN receptor-associated protein of the synapse 0.0100589
FGFR3 fibroblast growth factor receptor 3 0.0099624
HMGB3 high mobility group box 3 0.00995968
SHOX2 short stature homeobox 2 0.00992868
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00955359
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00951344
TUBB4B tubulin, beta 4B class IVb 0.009512
ZBTB18 zinc finger and BTB domain containing 18 0.00941935
COPS7A COP9 signalosome subunit 7A 0.00927595
TPI1 triosephosphate isomerase 1 0.00923283
SLC2A4RG SLC2A4 regulator 0.00920389
TMSB15A thymosin beta 15a 0.00914491
HMGN5 high mobility group nucleosome binding domain 5 0.00905252
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00898885
TRMT5 tRNA methyltransferase 5 0.00892212
IGFBP4 insulin-like growth factor binding protein 4 0.00885549
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00884118
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00872711
BCHE butyrylcholinesterase 0.00867358
PRODH proline dehydrogenase (oxidase) 1 0.00863104
APMAP adipocyte plasma membrane associated protein 0.00859661
IGFBP1 insulin-like growth factor binding protein 1 0.00858835
COL1A2 collagen, type I, alpha 2 0.00856306
GSTA4 glutathione S-transferase alpha 4 0.00853669
HAL histidine ammonia-lyase 0.00853558
TK1 thymidine kinase 1, soluble 0.00838304
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00837872
RXRA retinoid X receptor, alpha 0.00821797
LIG1 ligase I, DNA, ATP-dependent 0.0081236
COL3A1 collagen, type III, alpha 1 0.00811409
HSDL2 hydroxysteroid dehydrogenase like 2 0.00810739
TSPAN12 tetraspanin 12 0.00803851
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.00803602
NRGN neurogranin (protein kinase C substrate, RC3) 0.00802626
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00799755
IFITM2 interferon induced transmembrane protein 2 0.00799179
PRC1 protein regulator of cytokinesis 1 0.00798232
NANOG Nanog homeobox 0.00791785
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.00788295
BIRC5 baculoviral IAP repeat containing 5 0.0078802
GTSE1 G-2 and S-phase expressed 1 0.00782156
PKM pyruvate kinase, muscle 0.00780764
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00780733
DCXR dicarbonyl/L-xylulose reductase 0.00779705
RRAGA Ras-related GTP binding A 0.0077913
FMO3 flavin containing monooxygenase 3 0.00777635
TMEM38B transmembrane protein 38B 0.00775685
RPA3 replication protein A3, 14kDa 0.00769828
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 0.00766771
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00765399
LRRC17 leucine rich repeat containing 17 0.00755068
LY6E lymphocyte antigen 6 complex, locus E 0.00754967
AKAP7 A kinase (PRKA) anchor protein 7 0.0075416
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.00753219
HMGN2 high mobility group nucleosomal binding domain 2 0.00753063
ARHGAP11A Rho GTPase activating protein 11A 0.00752821
TNC tenascin C 0.00752654
NES nestin 0.0074787
RMI1 RecQ mediated genome instability 1 0.00747551
ICMT isoprenylcysteine carboxyl methyltransferase 0.00745137
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00744388
CD81 CD81 molecule 0.00744189
PLK1 polo-like kinase 1 0.00743477
KANK2 KN motif and ankyrin repeat domains 2 0.0074138
DTWD1 DTW domain containing 1 0.00739636
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00739283
TEX30 testis expressed 30 0.00738327
FAM234B family with sequence similarity 234 member B 0.00737316
HDAC6 histone deacetylase 6 0.0073699
GRAMD1C GRAM domain containing 1C 0.00736794
HELLS helicase, lymphoid-specific 0.00735466
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00732646
H2AX H2A.X variant histone 0.00732166
SALL1 spalt-like transcription factor 1 0.00729823
NSD2 nuclear receptor binding SET domain protein 2 0.00725901
SUB1 SUB1 homolog (S. cerevisiae) 0.00722924
ENO1 enolase 1, (alpha) 0.00719812
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.0071541
OIP5 Opa interacting protein 5 0.00713304
LMNB1 lamin B1 0.00712514
ELOVL5 ELOVL fatty acid elongase 5 0.00711037
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00709274
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00709204
EMP3 epithelial membrane protein 3 0.00705664
KRT2 keratin 2, type II 0.00704299
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00704138
TBCD tubulin folding cofactor D 0.00703811
HMGB2 high mobility group box 2 0.00703624
KIF18B kinesin family member 18B 0.00703056
ARHGAP19 Rho GTPase activating protein 19 0.00703037
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00702798
NOTCH3 notch 3 0.00701414
BHMT2 betaine--homocysteine S-methyltransferase 2 0.00701088
FBP1 fructose-1,6-bisphosphatase 1 0.00700923
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 0.00699074
NT5DC2 5'-nucleotidase domain containing 2 0.00697941
JAG2 jagged 2 0.00695019
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00694301
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 0.00694274
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00691785
SOCS5 suppressor of cytokine signaling 5 0.00685648
SFTPB surfactant protein B 0.00684487
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00684165
HMGB1 high mobility group box 1 0.00683954
CDT1 chromatin licensing and DNA replication factor 1 0.00683432
CXCL14 chemokine (C-X-C motif) ligand 14 0.00683219
FHOD1 formin homology 2 domain containing 1 0.006771
PFKL phosphofructokinase, liver 0.00673773
PCNXL4 pecanex-like 4 (Drosophila) 0.00672132
METTL7A methyltransferase like 7A 0.00672055
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00671256
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00671175
KRT1 keratin 1, type II 0.00669676
NMU neuromedin U 0.00668964
TARDBP TAR DNA binding protein 0.0066618
CDC7 cell division cycle 7 0.00665949
NTS neurotensin 0.00665486
TMX1 thioredoxin-related transmembrane protein 1 0.00662543
DBF4 DBF4 zinc finger 0.00661616
ENO2 enolase 2 (gamma, neuronal) 0.0066156
NEK2 NIMA-related kinase 2 0.00661153
CTBP1 C-terminal binding protein 1 0.00660303
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0066029
TEAD4 TEA domain family member 4 0.0065948
LCE2B late cornified envelope 2B 0.00658697
LINC00094 long intergenic non-protein coding RNA 94 0.00657536
GBAP1 glucosidase, beta, acid pseudogene 1 0.0065364
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.00651454
CEP43 centrosomal protein 43 0.0065102
DHFR dihydrofolate reductase 0.00650608
GRAMD4 GRAM domain containing 4 0.00650514
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00650208
SPC25 SPC25, NDC80 kinetochore complex component 0.00648601
ARG1 arginase 1 0.00648533
TRIB2 tribbles pseudokinase 2 0.00646561
RAB20 RAB20, member RAS oncogene family 0.00645484
FAM149A family with sequence similarity 149, member A 0.00645174
SORBS3 sorbin and SH3 domain containing 3 0.00643604
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.00643431
CA12 carbonic anhydrase XII 0.00642017
GSTA1 glutathione S-transferase alpha 1 0.00641856
MCM6 minichromosome maintenance complex component 6 0.00641332
GGCT gamma-glutamylcyclotransferase 0.0064057
NCAPD3 non-SMC condensin II complex, subunit D3 0.00640162
ASF1B anti-silencing function 1B histone chaperone 0.00639895
RPA1 replication protein A1, 70kDa 0.00639668
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00638458
GLDC glycine dehydrogenase (decarboxylating) 0.00636926
KIAA0232 KIAA0232 0.00636782
DMD dystrophin 0.00636528
LOR loricrin 0.00636527
FBL fibrillarin 0.00635859
BHMT betaine--homocysteine S-methyltransferase 0.00635021
FADS1 fatty acid desaturase 1 0.00635019
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00634925
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00634105
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00633064
UBA1 ubiquitin-like modifier activating enzyme 1 0.00632103
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.00631451
ZFP36L1 ZFP36 ring finger protein-like 1 0.00631372
KIF4A kinesin family member 4A 0.00630899
FKTN fukutin 0.00630817
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00629611
CSK c-src tyrosine kinase 0.00629112
SLC38A4 solute carrier family 38, member 4 0.0062748
ADGRF5 adhesion G protein-coupled receptor F5 0.00626983
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00626958
RAD51AP1 RAD51 associated protein 1 0.00626836
VCAM1 vascular cell adhesion molecule 1 0.00626535
HMG20B high mobility group 20B 0.00625138
F12 coagulation factor XII (Hageman factor) 0.00622918
AQP9 aquaporin 9 0.0062179
G6PC glucose-6-phosphatase, catalytic subunit 0.00621014
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.00620924
FBXO3 F-box protein 3 0.00620559
PDS5B PDS5 cohesin associated factor B 0.00620394
PRKCSH protein kinase C substrate 80K-H 0.00620343
NUCB1 nucleobindin 1 0.00620083
THOC6 THO complex 6 0.00618572
CHEK2 checkpoint kinase 2 0.00617809
TROAP trophinin associated protein 0.00616758
UPB1 ureidopropionase, beta 0.00616712
EFHC2 EF-hand domain (C-terminal) containing 2 0.00616375
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00616175
ASMTL acetylserotonin O-methyltransferase-like 0.00616101
SPAG5 sperm associated antigen 5 0.00616018
PCGF2 polycomb group ring finger 2 0.00614936
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00614574
MPHOSPH9 M-phase phosphoprotein 9 0.00613817
FTO fat mass and obesity associated 0.00611643
NOTCH2NL notch 2 N-terminal like 0.00610564
CD320 CD320 molecule 0.00610289
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00609235
CRLF1 cytokine receptor-like factor 1 0.00608644
FEN1 flap structure-specific endonuclease 1 0.00608443
FAM3C family with sequence similarity 3, member C 0.00607549
TACC3 transforming, acidic coiled-coil containing protein 3 0.00607006
MCM2 minichromosome maintenance complex component 2 0.00606597
PIMREG PICALM interacting mitotic regulator 0.0060643
TUBGCP3 tubulin, gamma complex associated protein 3 0.00604935
DSC1 desmocollin 1 0.00603605
SHCBP1 SHC SH2-domain binding protein 1 0.00603366
CDC25B cell division cycle 25B 0.00602842
LTA4H leukotriene A4 hydrolase 0.0060211
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00601948
HOPX HOP homeobox 0.00599808
DAPK1 death-associated protein kinase 1 0.00599541
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.0059913
ELOVL2 ELOVL fatty acid elongase 2 0.00598463
NHLRC2 NHL repeat containing 2 0.00596158
CDC20 cell division cycle 20 0.00595768
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00594883
PLCH1 phospholipase C, eta 1 0.00594163
PMF1 polyamine-modulated factor 1 0.00593551
HABP2 hyaluronan binding protein 2 0.00593245
KIF15 kinesin family member 15 0.00593189
PCLAF PCNA clamp associated factor 0.00592352
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00592079
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00590993
C1ORF174 chromosome 1 open reading frame 174 0.0059068
ANXA6 annexin A6 0.00589958
RBM14 RNA binding motif protein 14 0.00589003
NOTCH2 notch 2 0.00588039
DGKZ diacylglycerol kinase, zeta 0.00587959
RTN1 reticulon 1 0.0058652
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.005865
SPON2 spondin 2, extracellular matrix protein 0.00586458
ISYNA1 inositol-3-phosphate synthase 1 0.00585163

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -0.0229736
CRYAB crystallin, alpha B -0.0178946
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0177618
HSPA1A heat shock 70kDa protein 1A -0.0171607
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0168195
FABP4 fatty acid binding protein 4, adipocyte -0.0165294
ANXA1 annexin A1 -0.0155538
TM4SF1 transmembrane 4 L six family member 1 -0.0155409
IFI27 interferon, alpha-inducible protein 27 -0.0152348
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0151472
HMOX1 heme oxygenase 1 -0.0146803
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.0145218
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.0141389
COG7 component of oligomeric golgi complex 7 -0.0138174
ATF3 activating transcription factor 3 -0.0134609
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0133959
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0132918
HIST1H2AC histone cluster 1, H2ac -0.0132206
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0130697
AKAP12 A kinase (PRKA) anchor protein 12 -0.012426
FHL1 four and a half LIM domains 1 -0.0123485
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.0123459
KRT7 keratin 7, type II -0.0122901
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.012205
CEMIP cell migration inducing protein, hyaluronan binding -0.0121697
PERP PERP, TP53 apoptosis effector -0.0118126
EIF5A eukaryotic translation initiation factor 5A -0.0117188
CHGB chromogranin B -0.0116095
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0115927
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0114457
GSN gelsolin -0.0113337
ANXA3 annexin A3 -0.0113072
NEBL nebulette -0.0112917
CCN2 cellular communication network factor 2 -0.0112719
CFD complement factor D (adipsin) -0.0112497
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0112324
TPD52L1 tumor protein D52-like 1 -0.0112197
CALB1 calbindin 1, 28kDa -0.0111123
KYNU kynureninase -0.011083
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.010881
MAL mal, T-cell differentiation protein -0.0108614
HIST1H2BK histone cluster 1, H2bk -0.0108575
TSPAN1 tetraspanin 1 -0.0106935
FXYD3 FXYD domain containing ion transport regulator 3 -0.0106596
NCAM1 neural cell adhesion molecule 1 -0.0105931
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.0105888
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0105756
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0105612
SLC38A1 solute carrier family 38, member 1 -0.0104989
HIST1H2BD histone cluster 1, H2bd -0.010442
MAP7 microtubule-associated protein 7 -0.0103913
ABAT 4-aminobutyrate aminotransferase -0.0103241
PPARG peroxisome proliferator-activated receptor gamma -0.0102067
RHOBTB3 Rho-related BTB domain containing 3 -0.0102057
ESRP1 epithelial splicing regulatory protein 1 -0.0101491
PALLD palladin, cytoskeletal associated protein -0.0100796
PEG10 paternally expressed 10 -0.00999426
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00994295
COL15A1 collagen, type XV, alpha 1 -0.00992219
ZBED2 zinc finger, BED-type containing 2 -0.00987806
PCDH9 protocadherin 9 -0.00987743
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00983021
SPRR3 small proline-rich protein 3 -0.00982133
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00979258
CST1 cystatin SN -0.0097296
TENT5A terminal nucleotidyltransferase 5A -0.00965679
TFF1 trefoil factor 1 -0.00957354
SLPI secretory leukocyte peptidase inhibitor -0.00957003
OPTN optineurin -0.00955983
KLF5 Kruppel-like factor 5 (intestinal) -0.00954895
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00950347
FHL2 four and a half LIM domains 2 -0.0094956
FN1 fibronectin 1 -0.0094949
TSPAN8 tetraspanin 8 -0.00946666
KLK10 kallikrein-related peptidase 10 -0.00945826
RND3 Rho family GTPase 3 -0.00945189
AKR1C2 aldo-keto reductase family 1, member C2 -0.00939629
PSCA prostate stem cell antigen -0.0093937
BMP4 bone morphogenetic protein 4 -0.00937861
TFPI2 tissue factor pathway inhibitor 2 -0.00936943
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00935216
BHLHE41 basic helix-loop-helix family, member e41 -0.00913582
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00910922
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00908177
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00907504
ZNF652 zinc finger protein 652 -0.00905515
MT1X metallothionein 1X -0.00903957
F3 coagulation factor III (thromboplastin, tissue factor) -0.0090283
MAGEA3 melanoma antigen family A3 -0.00902716
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00901871
KRT81 keratin 81, type II -0.00898221
ETHE1 ethylmalonic encephalopathy 1 -0.00893288
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00893282
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00889892
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00888711
PEG3 paternally expressed 3 -0.00887316
MIR22HG MIR22 host gene -0.00886771
LXN latexin -0.00885852
FILIP1L filamin A interacting protein 1-like -0.0088359
MGP matrix Gla protein -0.00882878
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0087969
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00874455
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00865576
CPE carboxypeptidase E -0.00860165
ZNF91 zinc finger protein 91 -0.00858283
EGR1 early growth response 1 -0.00857987
RCAN1 regulator of calcineurin 1 -0.00857705
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00855285
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00851841
PRNP prion protein -0.00850535
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0085041
DCN decorin -0.00850154
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00849534
GLOD4 glyoxalase domain containing 4 -0.00849496
EIF5 eukaryotic translation initiation factor 5 -0.00847931
ELL2 elongation factor, RNA polymerase II, 2 -0.00846378
GPNMB glycoprotein (transmembrane) nmb -0.00845194
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.008416
GPX2 glutathione peroxidase 2 -0.00841576
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00841318
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00839329
ECM1 extracellular matrix protein 1 -0.00837891
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00836546
INHBA inhibin, beta A -0.008356
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.00834595
KLHL24 kelch-like family member 24 -0.00830719
LCN2 lipocalin 2 -0.00828966
MFSD1 major facilitator superfamily domain containing 1 -0.00827246
PRSS23 protease, serine, 23 -0.00826343
SGCE sarcoglycan, epsilon -0.00825181
CLDN7 claudin 7 -0.00824297
BEX4 brain expressed, X-linked 4 -0.00823921
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00821703
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00818086
FMOD fibromodulin -0.00816978
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00814339
ATP10B ATPase, class V, type 10B -0.00812635
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00812265
FGF13 fibroblast growth factor 13 -0.00810471
LMCD1 LIM and cysteine-rich domains 1 -0.00805977
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00803874
MXRA5 matrix-remodelling associated 5 -0.00801408
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00800853
EMP1 epithelial membrane protein 1 -0.00800488
RBM34 RNA binding motif protein 34 -0.00796717
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00795212
MT1G metallothionein 1G -0.00794637
COG5 component of oligomeric golgi complex 5 -0.00793361
RTCA RNA 3'-terminal phosphate cyclase -0.00793202
ISG20 interferon stimulated exonuclease gene 20kDa -0.00792275
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00787774
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00787749
HIST2H2BE histone cluster 2, H2be -0.00783687
FERMT1 fermitin family member 1 -0.00782519
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00781594
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00781479
AGR2 anterior gradient 2 -0.00779347
BCAS1 breast carcinoma amplified sequence 1 -0.00778883
RRAGC Ras-related GTP binding C -0.00778704
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00777435
LBH limb bud and heart development -0.00777333
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.0077633
MMP12 matrix metallopeptidase 12 -0.00775493
AKIRIN1 akirin 1 -0.00771305
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00771288
SAMD9 sterile alpha motif domain containing 9 -0.00770847
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00769397
BIK BCL2-interacting killer (apoptosis-inducing) -0.00768491
KLF6 Kruppel-like factor 6 -0.00768192
HSPE1 heat shock 10kDa protein 1 -0.00765484
LIMK2 LIM domain kinase 2 -0.00765464
UBE2H ubiquitin-conjugating enzyme E2H -0.00764826
ACP1 acid phosphatase 1, soluble -0.00764721
RASA4 RAS p21 protein activator 4 -0.00764246
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00761953
TMPRSS2 transmembrane protease, serine 2 -0.0076177
PRSS21 protease, serine, 21 (testisin) -0.00761076
CTTN cortactin -0.00758829
MYRF myelin regulatory factor -0.00755638
RIOK3 RIO kinase 3 -0.00755262
LPIN1 lipin 1 -0.00751756
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00751138
DSC2 desmocollin 2 -0.007511
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00749754
IRS2 insulin receptor substrate 2 -0.00749405
IFNGR1 interferon gamma receptor 1 -0.00748527
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00748
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00747521
LAMC2 laminin, gamma 2 -0.00745843
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0074339
IL6ST interleukin 6 signal transducer -0.0074135
ABLIM1 actin binding LIM protein 1 -0.0074105
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00740706
AREG amphiregulin -0.00740582
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00740126
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00739468
GOLGA8A golgin A8 family, member A -0.00735523
NRCAM neuronal cell adhesion molecule -0.00734629
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0073414
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00732765
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00730762
CTSZ cathepsin Z -0.00730503
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00729951
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0072766
CTSS cathepsin S -0.00727606
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00727563
MMP7 matrix metallopeptidase 7 -0.00726513
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00724656
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00721682
CCNA2 cyclin A2 -0.00720801
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00720155
FAM198B family with sequence similarity 198, member B -0.00719825
TRIM29 tripartite motif containing 29 -0.00719761
TNNC1 troponin C type 1 (slow) -0.00718754
DDIT3 DNA-damage-inducible transcript 3 -0.00718493
AGPS alkylglycerone phosphate synthase -0.00718377
SNAI2 snail family zinc finger 2 -0.00717613
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00717107
ITGA6 integrin, alpha 6 -0.00712523
MX1 MX dynamin-like GTPase 1 -0.00711765
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00711576
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.00710815
ZNF430 zinc finger protein 430 -0.00709529
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00709405
LEPROT leptin receptor overlapping transcript -0.00708801
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00708291
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -0.00707677
SORBS1 sorbin and SH3 domain containing 1 -0.00706924
EPHA2 EPH receptor A2 -0.00704795
SERINC1 serine incorporator 1 -0.00704402
KRT19 keratin 19, type I -0.00703544
CLTB clathrin, light chain B -0.00702307
TP53I3 tumor protein p53 inducible protein 3 -0.00701022
KLK11 kallikrein-related peptidase 11 -0.00700398
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0069882
IFRD1 interferon-related developmental regulator 1 -0.00698484
KRT14 keratin 14, type I -0.00697588
OSBPL2 oxysterol binding protein-like 2 -0.00695679
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00694502
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00693792
C1S complement component 1, s subcomponent -0.00692273
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -0.00690568
MRPL18 mitochondrial ribosomal protein L18 -0.0068845
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.00687075
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00685551
MITF microphthalmia-associated transcription factor -0.00684966
ACTA1 actin, alpha 1, skeletal muscle -0.00682631
MVP major vault protein -0.00682221