LMO2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description LIM domain only 2 (rhombotin-like 1)|LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008] (NCBI Entrez Gene Database, 4005)
External Link http://www.ncbi.nlm.nih.gov/gene/4005
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44 interacting proteins for LMO2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AXIN1 axin 1
BEX2 brain expressed X-linked 2
C19ORF57 chromosome 19 open reading frame 57
CDC25A cell division cycle 25A
CDC5L cell division cycle 5-like
CORO1A coronin, actin binding protein, 1A
CORO1C coronin, actin binding protein, 1C
DAZAP2 DAZ associated protein 2
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELF2 E74-like factor 2 (ets domain transcription factor)
ERBB2IP erbb2 interacting protein
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
HNRNPM heterogeneous nuclear ribonucleoprotein M
ISL1 ISL LIM homeobox 1
KDM5A lysine (K)-specific demethylase 5A
KDM5B lysine (K)-specific demethylase 5B
KIF3B kinesin family member 3B
LDB1 LIM domain binding 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
NCAPH2 non-SMC condensin II complex, subunit H2
NHLH1 nescient helix loop helix 1
PHC2 polyhomeotic homolog 2 (Drosophila)
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RLIM ring finger protein, LIM domain interacting
SMAD2 SMAD family member 2
SP1 Sp1 transcription factor
SSBP2 single-stranded DNA binding protein 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STIP1 stress-induced phosphoprotein 1
TAL1 T-cell acute lymphocytic leukemia 1
TAL2 T-cell acute lymphocytic leukemia 2
TCF3 transcription factor 3
TLX3 T-cell leukemia homeobox 3
UBC ubiquitin C