LN-405 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

338 genes with high or low expression in LN-405 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
WNT2 wingless-type MMTV integration site family member 2 3.60177
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 3.59062
HPSE heparanase 3.11075
CXCL13 chemokine (C-X-C motif) ligand 13 2.84785
GRB10 growth factor receptor-bound protein 10 2.82863
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 2.67374
LBP lipopolysaccharide binding protein 2.54509
SOX3 SRY (sex determining region Y)-box 3 2.49596
SOD3 superoxide dismutase 3, extracellular 2.41206
FOXF1 forkhead box F1 2.39687
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.38104
CENPB centromere protein B, 80kDa 2.37702
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.32046
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 2.25417
A4GALT alpha 1,4-galactosyltransferase 2.24248
TUBG2 tubulin, gamma 2 2.21439
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.16151
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.14666
CD34 CD34 molecule 2.12307
IQSEC2 IQ motif and Sec7 domain 2 2.11328
CLDN10 claudin 10 2.08679
TGFB3 transforming growth factor, beta 3 2.05664
EFNB2 ephrin-B2 2.02959
FBLN1 fibulin 1 2.02622
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 1.99331
ARHGAP26 Rho GTPase activating protein 26 1.98809
ADCY8 adenylate cyclase 8 (brain) 1.97924
MRPS6 mitochondrial ribosomal protein S6 1.97804
SOX13 SRY (sex determining region Y)-box 13 1.94811
CH25H cholesterol 25-hydroxylase 1.94117
EN1 engrailed homeobox 1 1.93978
MTCL1 microtubule crosslinking factor 1 1.93454
ATG4A autophagy related 4A, cysteine peptidase 1.93454
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene 1.92567
KIAA1661 KIAA1661 protein 1.92213
TBC1D17 TBC1 domain family, member 17 1.92157
KIF13A kinesin family member 13A 1.92142
TFE3 transcription factor binding to IGHM enhancer 3 1.89936
CROT carnitine O-octanoyltransferase 1.89557
MUM1 melanoma associated antigen (mutated) 1 1.89016
ACVR2A activin A receptor, type IIA 1.88336
ZDHHC14 zinc finger, DHHC-type containing 14 1.87013
ELMO2 engulfment and cell motility 2 1.84952
TP53I11 tumor protein p53 inducible protein 11 1.84727
EML2 echinoderm microtubule associated protein like 2 1.8467
FLOT1 flotillin 1 1.83986
MX2 MX dynamin-like GTPase 2 1.83677
MX1 MX dynamin-like GTPase 1 1.83393
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1.82803
CRYAB crystallin, alpha B 1.82642
NKX3-2 NK3 homeobox 2 1.80957
IFI35 interferon-induced protein 35 1.79778
SYNJ2 synaptojanin 2 1.79675
SLC22A17 solute carrier family 22, member 17 1.78994
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.77572
CDH4 cadherin 4, type 1, R-cadherin (retinal) 1.77458
MAGED2 melanoma antigen family D2 1.77119
IFI6 interferon, alpha-inducible protein 6 1.76914
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 1.76075
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 1.75806
STX10 syntaxin 10 1.75257
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.75133
DLG5 discs, large homolog 5 (Drosophila) 1.74536
PSG1 pregnancy specific beta-1-glycoprotein 1 1.74495
FAM127A family with sequence similarity 127, member A 1.74347
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 1.74333
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.73503
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 1.73134
CA5B carbonic anhydrase VB, mitochondrial 1.72531
IRF7 interferon regulatory factor 7 1.71963
DENND2A DENN/MADD domain containing 2A 1.71802
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.71664
CCDC102B coiled-coil domain containing 102B 1.71414
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 1.71357
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.7106
MIER2 mesoderm induction early response 1, family member 2 1.70366
SAMHD1 SAM domain and HD domain 1 1.70047
LRRC2 leucine rich repeat containing 2 1.68919
ARMCX3 armadillo repeat containing, X-linked 3 1.67752
ZMAT5 zinc finger, matrin-type 5 1.67208
PEX6 peroxisomal biogenesis factor 6 1.67097
CD70 CD70 molecule 1.66675
ZBTB20 zinc finger and BTB domain containing 20 1.66655
HAP1 huntingtin-associated protein 1 1.65825
SPON2 spondin 2, extracellular matrix protein 1.65753
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.65324
LMF2 lipase maturation factor 2 1.6473
LPPR2 lipid phosphate phosphatase-related protein type 2 1.64356
RASL12 RAS-like, family 12 1.63898
IGFBP5 insulin-like growth factor binding protein 5 1.63415
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 1.62397
TKT transketolase 1.6172
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 1.61513
SACS sacsin molecular chaperone 1.6111
RGS9 regulator of G-protein signaling 9 1.59893
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.59804
PTPRA protein tyrosine phosphatase, receptor type, A 1.59648
DOK5 docking protein 5 1.59479
POFUT2 protein O-fucosyltransferase 2 1.5946
NF2 neurofibromin 2 (merlin) 1.58985
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 1.587
BMP1 bone morphogenetic protein 1 1.58298
USP11 ubiquitin specific peptidase 11 1.58105
NRSN2 neurensin 2 1.58001
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.5758
NES nestin 1.57521
FSCN1 fascin actin-bundling protein 1 1.57384
CXCL12 chemokine (C-X-C motif) ligand 12 1.57036
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.56814
PMEPA1 prostate transmembrane protein, androgen induced 1 1.56771
COL4A6 collagen, type IV, alpha 6 1.5594
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 1.55043
BAALC brain and acute leukemia, cytoplasmic 1.54643
DZIP1 DAZ interacting zinc finger protein 1 1.54133
HDAC6 histone deacetylase 6 1.54058
CDC25B cell division cycle 25B 1.53944
CCHCR1 coiled-coil alpha-helical rod protein 1 1.53442
DPF3 D4, zinc and double PHD fingers, family 3 1.52886
RNF216 ring finger protein 216 1.52551
WBP4 WW domain binding protein 4 1.5186
PSG2 pregnancy specific beta-1-glycoprotein 2 1.5166
PYGB phosphorylase, glycogen; brain 1.51557
GDF5 growth differentiation factor 5 1.51368
ZCCHC2 zinc finger, CCHC domain containing 2 1.51198
EPHA5 EPH receptor A5 1.511
EYA2 EYA transcriptional coactivator and phosphatase 2 1.51025
IRF3 interferon regulatory factor 3 1.51022
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.51019
CHMP6 charged multivesicular body protein 6 1.50737
MAGED1 melanoma antigen family D1 1.50333
XAF1 XIAP associated factor 1 1.49248
PANK2 pantothenate kinase 2 1.49122
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 1.4908
SRPX2 sushi-repeat containing protein, X-linked 2 1.4883
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 1.48577
TGFB1 transforming growth factor, beta 1 1.48574
MAN2B1 mannosidase, alpha, class 2B, member 1 1.47994
MAP2K2 mitogen-activated protein kinase kinase 2 1.46923
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 1.46884
OR7C2 olfactory receptor, family 7, subfamily C, member 2 1.46481
KIAA1024 KIAA1024 1.46401
GPS2 G protein pathway suppressor 2 1.45467
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.44777
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.4367
CNR1 cannabinoid receptor 1 (brain) 1.43492
ZNF75D zinc finger protein 75D 1.43444
ISG15 ISG15 ubiquitin-like modifier 1.43278
FAM50A family with sequence similarity 50, member A 1.42877
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.42092

low expression

Symbol Name Standardized Value
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -3.11637
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -3.08806
DNAH3 dynein, axonemal, heavy chain 3 -2.88539
ZNF747 zinc finger protein 747 -2.81047
TEX10 testis expressed 10 -2.67248
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) -2.65679
RPS27A ribosomal protein S27a -2.65512
OR2F2 olfactory receptor, family 2, subfamily F, member 2 -2.65499
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.64092
RBM19 RNA binding motif protein 19 -2.55449
RPL7A ribosomal protein L7a -2.54354
LRPPRC leucine-rich pentatricopeptide repeat containing -2.54308
MBD5 methyl-CpG binding domain protein 5 -2.5372
XPC xeroderma pigmentosum, complementation group C -2.53238
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.4806
DMC1 DNA meiotic recombinase 1 -2.46331
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -2.44205
IMMT inner membrane protein, mitochondrial -2.418
GRM1 glutamate receptor, metabotropic 1 -2.40177
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.38168
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.32667
PNMA3 paraneoplastic Ma antigen 3 -2.28103
RPL6 ribosomal protein L6 -2.27316
GTF2B general transcription factor IIB -2.26557
AGXT alanine-glyoxylate aminotransferase -2.2323
RPL12 ribosomal protein L12 -2.21567
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -2.19437
RPL4 ribosomal protein L4 -2.18148
GLRA3 glycine receptor, alpha 3 -2.17611
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.17584
RPS3A ribosomal protein S3A -2.16327
RPLP0 ribosomal protein, large, P0 -2.15598
CD40LG CD40 ligand -2.14873
NOP16 NOP16 nucleolar protein -2.14618
MRPL15 mitochondrial ribosomal protein L15 -2.12406
MRPS35 mitochondrial ribosomal protein S35 -2.10134
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.09244
KMT2D lysine (K)-specific methyltransferase 2D -2.07144
COG2 component of oligomeric golgi complex 2 -2.06678
NUP133 nucleoporin 133kDa -2.0571
RAB30 RAB30, member RAS oncogene family -2.02855
GK2 glycerol kinase 2 -1.99195
KLK5 kallikrein-related peptidase 5 -1.96807
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.95961
ANAPC1 anaphase promoting complex subunit 1 -1.95602
MTSS1 metastasis suppressor 1 -1.94688
INVS inversin -1.94548
GPR88 G protein-coupled receptor 88 -1.94307
WDR33 WD repeat domain 33 -1.93826
RPL35A ribosomal protein L35a -1.92839
NVL nuclear VCP-like -1.92742
MGMT O-6-methylguanine-DNA methyltransferase -1.90886
ZCCHC4 zinc finger, CCHC domain containing 4 -1.89007
RPL3 ribosomal protein L3 -1.8847
RGS10 regulator of G-protein signaling 10 -1.87931
PLA2R1 phospholipase A2 receptor 1, 180kDa -1.86405
TMEM185B transmembrane protein 185B -1.86381
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -1.85933
RPL9 ribosomal protein L9 -1.84914
FASTKD2 FAST kinase domains 2 -1.84476
RPLP1 ribosomal protein, large, P1 -1.83497
UMPS uridine monophosphate synthetase -1.82593
TMEM131 transmembrane protein 131 -1.81603
NACA nascent polypeptide-associated complex alpha subunit -1.81556
TPRKB TP53RK binding protein -1.80506
ISCA1 iron-sulfur cluster assembly 1 -1.80356
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.80105
ZNF214 zinc finger protein 214 -1.79916
RPL10A ribosomal protein L10a -1.79593
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -1.79549
GMCL1 germ cell-less, spermatogenesis associated 1 -1.78927
OXA1L oxidase (cytochrome c) assembly 1-like -1.78707
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.78542
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -1.78466
PIP prolactin-induced protein -1.78226
CELA3A chymotrypsin-like elastase family, member 3A -1.76997
STOML2 stomatin (EPB72)-like 2 -1.76788
CAMK2A calcium/calmodulin-dependent protein kinase II alpha -1.76133
RPL30 ribosomal protein L30 -1.75303
CLUL1 clusterin-like 1 (retinal) -1.748
CLCA1 chloride channel accessory 1 -1.73345
SPRR1B small proline-rich protein 1B -1.73133
MAGEA4 melanoma antigen family A4 -1.72993
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -1.72811
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -1.72799
IAPP islet amyloid polypeptide -1.72327
FBXO28 F-box protein 28 -1.72204
EIF3A eukaryotic translation initiation factor 3, subunit A -1.72084
RPL31 ribosomal protein L31 -1.71789
CCDC70 coiled-coil domain containing 70 -1.7047
ASB7 ankyrin repeat and SOCS box containing 7 -1.68702
CUL1 cullin 1 -1.68264
GHRHR growth hormone releasing hormone receptor -1.66565
GPR173 G protein-coupled receptor 173 -1.66298
SRSF7 serine/arginine-rich splicing factor 7 -1.66135
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.65858
EIF3FP2 eukaryotic translation initiation factor 3, subunit F pseudogene 2 -1.64743
STXBP6 syntaxin binding protein 6 (amisyn) -1.64272
RPS12 ribosomal protein S12 -1.63488
SBNO1 strawberry notch homolog 1 (Drosophila) -1.62892
GLRA1 glycine receptor, alpha 1 -1.62832
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -1.6163
IRAK3 interleukin-1 receptor-associated kinase 3 -1.61243
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -1.61081
OLFML1 olfactomedin-like 1 -1.60727
LENEP lens epithelial protein -1.59879
GLE1 GLE1 RNA export mediator -1.59595
S100A5 S100 calcium binding protein A5 -1.58599
RPL32 ribosomal protein L32 -1.58516
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -1.58193
NYNRIN NYN domain and retroviral integrase containing -1.57865
CCT2 chaperonin containing TCP1, subunit 2 (beta) -1.56992
CPA2 carboxypeptidase A2 (pancreatic) -1.56824
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -1.56422
PRMT5 protein arginine methyltransferase 5 -1.55815
CALB2 calbindin 2 -1.55809
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 -1.55462
PCDHA9 protocadherin alpha 9 -1.54859
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -1.54439
RPS17 ribosomal protein S17 -1.53848
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -1.53812
KRT3 keratin 3, type II -1.53517
RPL7 ribosomal protein L7 -1.53377
EIF3E eukaryotic translation initiation factor 3, subunit E -1.53239
HNRNPF heterogeneous nuclear ribonucleoprotein F -1.52551
MTIF2 mitochondrial translational initiation factor 2 -1.52387
RPL35 ribosomal protein L35 -1.52018
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 -1.51889
RAN RAN, member RAS oncogene family -1.5173
STYK1 serine/threonine/tyrosine kinase 1 -1.5173
MOB3B MOB kinase activator 3B -1.50715
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -1.50641
ANKHD1 ankyrin repeat and KH domain containing 1 -1.50547
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -1.50458
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.50395
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.50061
UBA5 ubiquitin-like modifier activating enzyme 5 -1.49754
HMHB1 histocompatibility (minor) HB-1 -1.49736
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.49548
RPL24 ribosomal protein L24 -1.49505
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding) -1.49168
ANGEL2 angel homolog 2 (Drosophila) -1.49049
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.48931
YOD1 YOD1 deubiquitinase -1.48539
CELP carboxyl ester lipase pseudogene -1.48006
SSBP1 single-stranded DNA binding protein 1, mitochondrial -1.47998
MEF2A myocyte enhancer factor 2A -1.4766
KLK12 kallikrein-related peptidase 12 -1.47485
WDR73 WD repeat domain 73 -1.47377
PLEK2 pleckstrin 2 -1.47166
LRRC31 leucine rich repeat containing 31 -1.4704
CD247 CD247 molecule -1.46682
EIF4B eukaryotic translation initiation factor 4B -1.46263
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -1.46241
EIF3H eukaryotic translation initiation factor 3, subunit H -1.46238
PCBP1 poly(rC) binding protein 1 -1.46177
CNBP CCHC-type zinc finger, nucleic acid binding protein -1.45875
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -1.457
KDM4A lysine (K)-specific demethylase 4A -1.4557
APOC4 apolipoprotein C-IV -1.45535
WDR43 WD repeat domain 43 -1.45238
TSN translin -1.4499
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.4498
TBX3 T-box 3 -1.44868
AQR aquarius intron-binding spliceosomal factor -1.44605
KCTD3 potassium channel tetramerization domain containing 3 -1.446
MRPS17 mitochondrial ribosomal protein S17 -1.44507
ZC3H15 zinc finger CCCH-type containing 15 -1.44484
COMMD3 COMM domain containing 3 -1.44045
TMC5 transmembrane channel-like 5 -1.43937
FPR3 formyl peptide receptor 3 -1.43874
SRP9 signal recognition particle 9kDa -1.43865
INTS7 integrator complex subunit 7 -1.43834
RAG1 recombination activating gene 1 -1.43789
GALR3 galanin receptor 3 -1.43767
GOLGA8A golgin A8 family, member A -1.43621
CEP97 centrosomal protein 97kDa -1.43494
PTPRN protein tyrosine phosphatase, receptor type, N -1.42884
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.42881
PDCD10 programmed cell death 10 -1.42691
COX5A cytochrome c oxidase subunit Va -1.42664
COPS2 COP9 signalosome subunit 2 -1.42468
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus -1.42465
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -1.42246
TKTL1 transketolase-like 1 -1.42152
EML4 echinoderm microtubule associated protein like 4 -1.42004
AVPR1B arginine vasopressin receptor 1B -1.41894
MTPAP mitochondrial poly(A) polymerase -1.41725
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.41652