| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | lipoprotein, Lp(a)|The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 4018) |
| External Link | https://ncbi.nlm.nih.gov/gene/4018 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the LPA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| METTL7A | methyltransferase like 7A | 0.0135934 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0130184 |
| SORD | sorbitol dehydrogenase | 0.0125746 |
| ZIC1 | Zic family member 1 | 0.0125441 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0122843 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.012069 |
| TADA2A | transcriptional adaptor 2A | 0.0119336 |
| PLK1 | polo-like kinase 1 | 0.0117556 |
| NEFH | neurofilament, heavy polypeptide | 0.0116604 |
| RB1 | retinoblastoma 1 | 0.0114334 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0113692 |
| CHN2 | chimerin 2 | 0.011208 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0111239 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.0108071 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0106955 |
| NRN1 | neuritin 1 | 0.0104099 |
| MAL | mal, T-cell differentiation protein | 0.0103564 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0103283 |
| FABP1 | fatty acid binding protein 1, liver | 0.01017 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00999625 |
| FCGBP | Fc fragment of IgG binding protein | 0.00977376 |
| HAT1 | histone acetyltransferase 1 | 0.00972339 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00969381 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00966336 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00961657 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00959885 |
| ABHD6 | abhydrolase domain containing 6 | 0.00956262 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00935687 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0092343 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00912719 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00911671 |
| XPO7 | exportin 7 | 0.00911578 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00905977 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00878617 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0087799 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00874175 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00866612 |
| BEX1 | brain expressed, X-linked 1 | 0.00864684 |
| LPXN | leupaxin | 0.00863644 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00861838 |
| PDZK1 | PDZ domain containing 1 | 0.00855055 |
| ASRGL1 | asparaginase like 1 | 0.00848784 |
| STK10 | serine/threonine kinase 10 | 0.00848387 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00841986 |
| ITM2A | integral membrane protein 2A | 0.00836912 |
| HBD | hemoglobin, delta | 0.00829437 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00822771 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00822205 |
| CRYL1 | crystallin, lambda 1 | 0.00812563 |
| S100B | S100 calcium binding protein B | 0.00807176 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00805398 |
| LIMA1 | LIM domain and actin binding 1 | 0.00803316 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00794249 |
| GJB1 | gap junction protein, beta 1, 32kDa | 0.0078957 |
| CDCA4 | cell division cycle associated 4 | 0.00788901 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00786681 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00786412 |
| TSPAN8 | tetraspanin 8 | 0.0078413 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00783015 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00780038 |
| CLCA1 | chloride channel accessory 1 | 0.0077898 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00776979 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00767788 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.0076698 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0076334 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00758033 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00754533 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0075244 |
| RPS5 | ribosomal protein S5 | 0.00751957 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00750272 |
| KLK6 | kallikrein-related peptidase 6 | 0.00748992 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00748161 |
| OLFM1 | olfactomedin 1 | 0.00746437 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00745921 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00744304 |
| TMEM176A | transmembrane protein 176A | 0.00743872 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | 0.00743708 |
| APOM | apolipoprotein M | 0.00737356 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00732934 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00731951 |
| DEFB1 | defensin, beta 1 | 0.00730694 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00730583 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00728326 |
| JAM3 | junctional adhesion molecule 3 | 0.00727353 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00725296 |
| NAAA | N-acylethanolamine acid amidase | 0.0072402 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.0072049 |
| QDPR | quinoid dihydropteridine reductase | 0.00717709 |
| CD96 | CD96 molecule | 0.00716311 |
| EVL | Enah/Vasp-like | 0.00713927 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00713081 |
| ZG16 | zymogen granule protein 16 | 0.00712871 |
| TMEM176B | transmembrane protein 176B | 0.00712738 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00711755 |
| PER3 | period circadian clock 3 | 0.0070731 |
| SEPTIN10 | septin 10 | 0.0070651 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00701263 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00700622 |
| TOR1A | torsin family 1, member A (torsin A) | 0.0070004 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00699905 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00699531 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00698754 |
| APOC2 | apolipoprotein C-II | 0.00695421 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00695392 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00694457 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00694257 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00693068 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00688986 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00687199 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00685059 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00684701 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00682164 |
| SPAG16 | sperm associated antigen 16 | 0.00681508 |
| TLR4 | toll-like receptor 4 | 0.0068053 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00679954 |
| S100A7 | S100 calcium binding protein A7 | 0.00676799 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00675817 |
| FGL2 | fibrinogen-like 2 | 0.00672247 |
| TEX10 | testis expressed 10 | 0.00669859 |
| CRYM | crystallin, mu | 0.00669351 |
| AHNAK | AHNAK nucleoprotein | 0.00667253 |
| IL2RG | interleukin 2 receptor, gamma | 0.00666234 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00665093 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00663222 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00662942 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00662395 |
| MT1E | metallothionein 1E | 0.00657129 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00657127 |
| AK4 | adenylate kinase 4 | 0.00657019 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00656254 |
| MYO1C | myosin IC | 0.00650563 |
| SELL | selectin L | 0.00650252 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00647516 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00646622 |
| HLTF | helicase-like transcription factor | 0.00645517 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0064524 |
| HOXC6 | homeobox C6 | 0.0064404 |
| PAH | phenylalanine hydroxylase | 0.00643312 |
| CD8A | CD8a molecule | 0.00642571 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.00639629 |
| CMC2 | C-x(9)-C motif containing 2 | 0.00639179 |
| LEPR | leptin receptor | 0.00636297 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00635487 |
| TXN | thioredoxin | 0.00635322 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00634809 |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) | 0.00633559 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00632956 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00632894 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00630292 |
| COG2 | component of oligomeric golgi complex 2 | 0.00626033 |
| CTSW | cathepsin W | 0.00626018 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00625901 |
| KHK | ketohexokinase (fructokinase) | 0.00625652 |
| NOS3 | nitric oxide synthase 3 (endothelial cell) | 0.00625226 |
| SERINC5 | serine incorporator 5 | 0.00624927 |
| TSPAN1 | tetraspanin 1 | 0.00624218 |
| ADD3 | adducin 3 (gamma) | 0.00623206 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00622939 |
| ITM2C | integral membrane protein 2C | 0.00622505 |
| HOXB2 | homeobox B2 | 0.00620092 |
| NVL | nuclear VCP-like | 0.00617336 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00617185 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00615887 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0061417 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00612972 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00610588 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | 0.00610203 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00609425 |
| ACVR1 | activin A receptor, type I | 0.00608469 |
| PIPOX | pipecolic acid oxidase | 0.00607689 |
| GATA2 | GATA binding protein 2 | 0.00606349 |
| LTF | lactotransferrin | 0.00605991 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00605595 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.0060536 |
| IL17RB | interleukin 17 receptor B | 0.00604229 |
| INSM1 | insulinoma-associated 1 | 0.00601444 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00600505 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00599467 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00598233 |
| TARP | TCR gamma alternate reading frame protein | 0.00597309 |
| AIF1 | allograft inflammatory factor 1 | 0.005964 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00595597 |
| EMP3 | epithelial membrane protein 3 | 0.00593586 |
| STMN2 | stathmin 2 | 0.00593222 |
| BIN2 | bridging integrator 2 | 0.00592994 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00591048 |
| LAGE3 | L antigen family, member 3 | 0.00590181 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00589938 |
| PRF1 | perforin 1 (pore forming protein) | 0.00589628 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.0058947 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00588757 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.00588464 |
| EPHB2 | EPH receptor B2 | 0.0058834 |
| LOR | loricrin | 0.00587915 |
| TEX30 | testis expressed 30 | 0.00587871 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00587749 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00584998 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00584352 |
| GPM6B | glycoprotein M6B | 0.00582944 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.0058254 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0058098 |
| FLNC | filamin C, gamma | 0.00579793 |
| RGS10 | regulator of G-protein signaling 10 | 0.00579489 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00578137 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00577588 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00576527 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00576192 |
| TLK1 | tousled-like kinase 1 | 0.00575683 |
| SATB2 | SATB homeobox 2 | 0.00575227 |
| UNG | uracil-DNA glycosylase | 0.00574818 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00574215 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00574062 |
| PEG3 | paternally expressed 3 | 0.00573571 |
| ADI1 | acireductone dioxygenase 1 | 0.00572554 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00571256 |
| ALAD | aminolevulinate dehydratase | 0.00570941 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00570813 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00568227 |
| MT1F | metallothionein 1F | 0.00567041 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00566303 |
| ESD | esterase D | 0.00565643 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.00562748 |
| ACP3 | acid phosphatase 3 | 0.00562718 |
| COL1A2 | collagen, type I, alpha 2 | 0.00562564 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | 0.00561099 |
| NELL2 | NEL-like 2 (chicken) | 0.00560696 |
| MT1G | metallothionein 1G | 0.00560566 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00559889 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00559767 |
| GRAMD1C | GRAM domain containing 1C | 0.00559653 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.00559578 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00558748 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00557122 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00556603 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | 0.00555889 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00554663 |
| MEN1 | multiple endocrine neoplasia I | 0.00554569 |
| NINJ2 | ninjurin 2 | 0.00554455 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00554361 |
| TTC38 | tetratricopeptide repeat domain 38 | 0.00554114 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00553126 |
| STEAP1B | STEAP family member 1B | 0.00552253 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00551352 |
| PALMD | palmdelphin | 0.00550953 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00550363 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00549932 |
| CD2 | CD2 molecule | 0.00549686 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00548812 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.00548555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2C | myocyte enhancer factor 2C | -0.0159102 |
| AREG | amphiregulin | -0.0145308 |
| STC2 | stanniocalcin 2 | -0.0113224 |
| GATA6 | GATA binding protein 6 | -0.0112319 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.0111845 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0109027 |
| PLCB4 | phospholipase C, beta 4 | -0.0108744 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.010624 |
| TRIB3 | tribbles pseudokinase 3 | -0.0105069 |
| KRT19 | keratin 19, type I | -0.0104266 |
| MMP9 | matrix metallopeptidase 9 | -0.00985199 |
| MYBPC1 | myosin binding protein C, slow type | -0.00970729 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00964699 |
| TNNC1 | troponin C type 1 (slow) | -0.00958133 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00957694 |
| ANXA3 | annexin A3 | -0.00954428 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00951783 |
| RGS13 | regulator of G-protein signaling 13 | -0.00950668 |
| GNAS | GNAS complex locus | -0.0094391 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00941831 |
| TLCD3A | TLC domain containing 3A | -0.00940464 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00933346 |
| CD163 | CD163 molecule | -0.00932426 |
| FBN2 | fibrillin 2 | -0.00927761 |
| AUTS2 | autism susceptibility candidate 2 | -0.00902864 |
| XAF1 | XIAP associated factor 1 | -0.00899303 |
| PLK2 | polo-like kinase 2 | -0.00888727 |
| PXDN | peroxidasin | -0.0087181 |
| SIK1 | salt-inducible kinase 1 | -0.00866601 |
| EREG | epiregulin | -0.00864373 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00863291 |
| ATP9A | ATPase, class II, type 9A | -0.00860917 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00835951 |
| ADORA2B | adenosine A2b receptor | -0.00834689 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00828495 |
| KLHL24 | kelch-like family member 24 | -0.00822596 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00820374 |
| SYNM | synemin, intermediate filament protein | -0.00812118 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0081204 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00808237 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00805255 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.0080282 |
| EGR1 | early growth response 1 | -0.00800822 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00800362 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0079889 |
| ATF3 | activating transcription factor 3 | -0.00797222 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00789504 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0078499 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00782538 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00776888 |
| TES | testin LIM domain protein | -0.00776809 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00775747 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00773393 |
| IRS2 | insulin receptor substrate 2 | -0.00771442 |
| PLXND1 | plexin D1 | -0.00770496 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00766608 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00761043 |
| CA12 | carbonic anhydrase XII | -0.0075412 |
| YME1L1 | YME1-like 1 ATPase | -0.0074691 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00746078 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00744062 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00741868 |
| RYR1 | ryanodine receptor 1 (skeletal) | -0.00741737 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00738324 |
| OLFML2A | olfactomedin-like 2A | -0.00734834 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00733824 |
| TMSB15A | thymosin beta 15a | -0.00732742 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00730854 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00727146 |
| TOX | thymocyte selection-associated high mobility group box | -0.00724817 |
| CCNA2 | cyclin A2 | -0.00721725 |
| ASPN | asporin | -0.00719254 |
| CDC20 | cell division cycle 20 | -0.00715944 |
| MYOF | myoferlin | -0.00713477 |
| KLHL41 | kelch-like family member 41 | -0.00712845 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00712399 |
| TESC | tescalcin | -0.00711703 |
| PMM2 | phosphomannomutase 2 | -0.00706963 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00706933 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00701003 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00698956 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00698952 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0069756 |
| MCL1 | myeloid cell leukemia 1 | -0.00696588 |
| MYO6 | myosin VI | -0.00696309 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00694843 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00691071 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00689434 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00688904 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00688166 |
| NKX2-1 | NK2 homeobox 1 | -0.0068588 |
| PEG10 | paternally expressed 10 | -0.00685655 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00685406 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00685043 |
| FGG | fibrinogen gamma chain | -0.00684196 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00683151 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00679946 |
| CD9 | CD9 molecule | -0.00675953 |
| PDE8B | phosphodiesterase 8B | -0.00672723 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.00670289 |
| CKM | creatine kinase, muscle | -0.00667969 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00667964 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00667607 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.0066723 |
| JMJD6 | jumonji domain containing 6 | -0.00662482 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.00661881 |
| MX1 | MX dynamin-like GTPase 1 | -0.00661409 |
| KRT7 | keratin 7, type II | -0.00661403 |
| TTN | titin | -0.00660892 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00659217 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.00658271 |
| CADM1 | cell adhesion molecule 1 | -0.0065779 |
| BCL6 | B-cell CLL/lymphoma 6 | -0.00657434 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00652706 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00651379 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00649681 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00648682 |
| PDE10A | phosphodiesterase 10A | -0.0064866 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00648609 |
| S100A8 | S100 calcium binding protein A8 | -0.00648097 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00645425 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.006436 |
| CTSB | cathepsin B | -0.00643307 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00641612 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00641404 |
| RIT1 | Ras-like without CAAX 1 | -0.00639929 |
| TLE4 | transducin-like enhancer of split 4 | -0.00639693 |
| GAB2 | GRB2-associated binding protein 2 | -0.00639639 |
| COL5A2 | collagen, type V, alpha 2 | -0.00638875 |
| YBX3 | Y box binding protein 3 | -0.00637442 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.00634515 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | -0.00633145 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.00630147 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00629542 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00628975 |
| RBM47 | RNA binding motif protein 47 | -0.00628068 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00627525 |
| PFKM | phosphofructokinase, muscle | -0.00626544 |
| NXN | nucleoredoxin | -0.0062604 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene | -0.00625382 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00625156 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00623733 |
| MARCO | macrophage receptor with collagenous structure | -0.00623508 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00623128 |
| SLN | sarcolipin | -0.00621526 |
| RBPMS | RNA binding protein with multiple splicing | -0.0062145 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.0062059 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00619495 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00615885 |
| LOXL2 | lysyl oxidase-like 2 | -0.00615053 |
| MB | myoglobin | -0.00612031 |
| ECM1 | extracellular matrix protein 1 | -0.00610773 |
| CTBP2 | C-terminal binding protein 2 | -0.00609519 |
| FAM13A | family with sequence similarity 13, member A | -0.00609474 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00602326 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00601979 |
| ROPN1B | rhophilin associated tail protein 1B | -0.00601826 |
| RGCC | regulator of cell cycle | -0.00601092 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00599973 |
| SMAD3 | SMAD family member 3 | -0.00598294 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -0.00597158 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00596851 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00595902 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00595448 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00595336 |
| TNNC2 | troponin C type 2 (fast) | -0.00593325 |
| ELANE | elastase, neutrophil expressed | -0.00592352 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00592296 |
| PLXNA1 | plexin A1 | -0.00591904 |
| MFGE8 | milk fat globule-EGF factor 8 protein | -0.00590967 |
| PLD3 | phospholipase D family, member 3 | -0.00590926 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00588971 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00588282 |
| GPR88 | G protein-coupled receptor 88 | -0.00587918 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00587319 |
| CCN2 | cellular communication network factor 2 | -0.00587267 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00586325 |
| PCDH9 | protocadherin 9 | -0.00585597 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.00584695 |
| TRIB1 | tribbles pseudokinase 1 | -0.00581986 |
| DSC2 | desmocollin 2 | -0.00581166 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00580505 |
| USP25 | ubiquitin specific peptidase 25 | -0.00580371 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.00580032 |
| FADS3 | fatty acid desaturase 3 | -0.00579912 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00579636 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00579276 |
| MDM4 | MDM4, p53 regulator | -0.00578732 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00577505 |
| AK1 | adenylate kinase 1 | -0.00577329 |
| RND3 | Rho family GTPase 3 | -0.00577167 |
| COCH | cochlin | -0.00576885 |
| ZNF117 | zinc finger protein 117 | -0.00576845 |
| PLPP2 | phospholipid phosphatase 2 | -0.00574974 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00572644 |
| ACTN1 | actinin, alpha 1 | -0.00568752 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.00567546 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -0.0056735 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00565544 |
| EPS8L2 | EPS8-like 2 | -0.0056554 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00565361 |
| C21ORF91 | chromosome 21 open reading frame 91 | -0.0056365 |
| LRRC2 | leucine rich repeat containing 2 | -0.00563422 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00563225 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00561139 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.00560971 |
| KRT18 | keratin 18, type I | -0.00560176 |
| MYOZ2 | myozenin 2 | -0.00559895 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00558938 |
| CD81 | CD81 molecule | -0.00558654 |
| RRBP1 | ribosome binding protein 1 | -0.00558512 |
| ZNF165 | zinc finger protein 165 | -0.00558496 |
| RCAN2 | regulator of calcineurin 2 | -0.00558106 |
| SIX3 | SIX homeobox 3 | -0.00556369 |
| RRAGD | Ras-related GTP binding D | -0.0055582 |
| KLF6 | Kruppel-like factor 6 | -0.00554909 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.0055489 |
| MSLN | mesothelin | -0.00554295 |
| VEGFA | vascular endothelial growth factor A | -0.00553029 |
| PKM | pyruvate kinase, muscle | -0.00550516 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00549677 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0054848 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00548279 |
| ZNF160 | zinc finger protein 160 | -0.00546371 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 | -0.00544142 |
| THBS2 | thrombospondin 2 | -0.00543791 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00541978 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00541551 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00541312 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00539982 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00539896 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00539584 |
| DST | dystonin | -0.00539169 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0053841 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00537716 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00537208 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00533929 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00533413 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00533299 |
| BMP2 | bone morphogenetic protein 2 | -0.00532683 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0053226 |
| COL2A1 | collagen, type II, alpha 1 | -0.00531669 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00531347 |
| VPREB3 | pre-B lymphocyte 3 | -0.00530221 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00529841 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00529737 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0052955 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00527476 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00526903 |
