| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)|The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] (NCBI Entrez Gene Database, 9227) |
| External Link | https://ncbi.nlm.nih.gov/gene/9227 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the LRAT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0318595 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0206607 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0205361 |
| LXN | latexin | 0.0164908 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.0147678 |
| C7 | complement component 7 | 0.0141587 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.0140688 |
| NEBL | nebulette | 0.0136333 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0135216 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.0133343 |
| TMEM100 | transmembrane protein 100 | 0.0130143 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.0123825 |
| CLU | clusterin | 0.0123266 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.0122041 |
| GPM6B | glycoprotein M6B | 0.0120434 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0119395 |
| TSPAN13 | tetraspanin 13 | 0.0116377 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0116109 |
| NRCAM | neuronal cell adhesion molecule | 0.0114304 |
| MSMB | microseminoprotein, beta- | 0.0114137 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.011274 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0112311 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0110334 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.011003 |
| CFI | complement factor I | 0.0108105 |
| MCAM | melanoma cell adhesion molecule | 0.0107848 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.010741 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0107163 |
| CDO1 | cysteine dioxygenase type 1 | 0.0106533 |
| IL33 | interleukin 33 | 0.0105249 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0102733 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0102552 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0102405 |
| STK10 | serine/threonine kinase 10 | 0.0101579 |
| ITM2C | integral membrane protein 2C | 0.0101473 |
| S100B | S100 calcium binding protein B | 0.0101417 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00989841 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00983798 |
| CFH | complement factor H | 0.00977329 |
| RELN | reelin | 0.00976938 |
| NRN1 | neuritin 1 | 0.0097496 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00971757 |
| PMP2 | peripheral myelin protein 2 | 0.00962086 |
| GPX3 | glutathione peroxidase 3 | 0.00957467 |
| LEPR | leptin receptor | 0.00954278 |
| MME | membrane metallo-endopeptidase | 0.00934722 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0093339 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00924996 |
| ACKR3 | atypical chemokine receptor 3 | 0.00917396 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00916248 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00914495 |
| PSAP | prosaposin | 0.00904924 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00904262 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00904062 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0090351 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00891443 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00888496 |
| MT1H | metallothionein 1H | 0.00888316 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00882411 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00875828 |
| S100P | S100 calcium binding protein P | 0.00875076 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | 0.00871345 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00868604 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00858095 |
| PTCH1 | patched 1 | 0.00855545 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00853058 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00846254 |
| CFD | complement factor D (adipsin) | 0.00845954 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00845231 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00840253 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00827501 |
| CLDN5 | claudin 5 | 0.00826148 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00824994 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00824516 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00822814 |
| PROM1 | prominin 1 | 0.00820331 |
| PCNA | proliferating cell nuclear antigen | 0.00819623 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00812819 |
| VWF | von Willebrand factor | 0.0080914 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00808188 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00807191 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00805123 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00804094 |
| ADIRF | adipogenesis regulatory factor | 0.00804025 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00803005 |
| SORD | sorbitol dehydrogenase | 0.00799343 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00799219 |
| NEFH | neurofilament, heavy polypeptide | 0.00798926 |
| FRZB | frizzled-related protein | 0.00796078 |
| WLS | wntless Wnt ligand secretion mediator | 0.00789887 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00785086 |
| GLUL | glutamate-ammonia ligase | 0.00784596 |
| PSCA | prostate stem cell antigen | 0.00783966 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.00777763 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00777569 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.00770377 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00769371 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00769178 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | 0.0076538 |
| CHRDL1 | chordin-like 1 | 0.00764975 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00764347 |
| KRT13 | keratin 13, type I | 0.0076336 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00762577 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00762022 |
| FOXF1 | forkhead box F1 | 0.00758928 |
| FGF13 | fibroblast growth factor 13 | 0.0075501 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00747554 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00747006 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00746828 |
| LTF | lactotransferrin | 0.00744834 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00738025 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00737974 |
| PLP1 | proteolipid protein 1 | 0.00737709 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00729894 |
| LAMB1 | laminin, beta 1 | 0.00729366 |
| TRH | thyrotropin-releasing hormone | 0.00729175 |
| ASRGL1 | asparaginase like 1 | 0.00728401 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00727462 |
| OPHN1 | oligophrenin 1 | 0.00726919 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00726196 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.00723785 |
| MSX1 | msh homeobox 1 | 0.00720762 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00720407 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00717583 |
| GPX1 | glutathione peroxidase 1 | 0.00715819 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00714877 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0071093 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00707656 |
| CANT1 | calcium activated nucleotidase 1 | 0.00706866 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00706418 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00703847 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00703095 |
| SST | somatostatin | 0.00700836 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00698906 |
| MT1G | metallothionein 1G | 0.00696098 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00696045 |
| EHD3 | EH-domain containing 3 | 0.00695544 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00693494 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00693365 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00692877 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00689869 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00688753 |
| CHEK2 | checkpoint kinase 2 | 0.00686563 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00686237 |
| HMGA1 | high mobility group AT-hook 1 | 0.0068225 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00680848 |
| LAMA4 | laminin, alpha 4 | 0.00678946 |
| HAMP | hepcidin antimicrobial peptide | 0.00675393 |
| RND3 | Rho family GTPase 3 | 0.00675074 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00674696 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00671535 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0066877 |
| TGM2 | transglutaminase 2 | 0.00668253 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00668128 |
| TFF1 | trefoil factor 1 | 0.0066725 |
| NDRG4 | NDRG family member 4 | 0.00664886 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00663419 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00662364 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00661323 |
| FZD10 | frizzled class receptor 10 | 0.00658693 |
| CH25H | cholesterol 25-hydroxylase | 0.00657559 |
| FBLN5 | fibulin 5 | 0.00654071 |
| EPHB2 | EPH receptor B2 | 0.00653527 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.00651853 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00646858 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00645505 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00645362 |
| TMEM35 | transmembrane protein 35 | 0.00644511 |
| BMP6 | bone morphogenetic protein 6 | 0.00643891 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00639407 |
| TRIM22 | tripartite motif containing 22 | 0.00638968 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00637305 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.00635877 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00635297 |
| ATP10B | ATPase, class V, type 10B | 0.00634251 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0063305 |
| RPL14 | ribosomal protein L14 | 0.00632438 |
| NHP2 | NHP2 ribonucleoprotein | 0.00632286 |
| PGLS | 6-phosphogluconolactonase | 0.00632097 |
| DENND3 | DENN/MADD domain containing 3 | 0.00630241 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00629749 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00626704 |
| CCDC85B | coiled-coil domain containing 85B | 0.00625908 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00625714 |
| USP6NL | USP6 N-terminal like | 0.00623758 |
| DCHS1 | dachsous cadherin-related 1 | 0.0062315 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00622502 |
| MAOA | monoamine oxidase A | 0.00621773 |
| CYTL1 | cytokine-like 1 | 0.00620698 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00619698 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.00618704 |
| ABHD2 | abhydrolase domain containing 2 | 0.00618404 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00618326 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00616779 |
| CD81 | CD81 molecule | 0.00614204 |
| BMP2 | bone morphogenetic protein 2 | 0.00614109 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00611829 |
| C1S | complement component 1, s subcomponent | 0.0060936 |
| AOX1 | aldehyde oxidase 1 | 0.00609041 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00608053 |
| H1-10 | H1.10 linker histone | 0.00606683 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.00604545 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00603576 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00603157 |
| SRI | sorcin | 0.00603029 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00602914 |
| PCGF2 | polycomb group ring finger 2 | 0.00602285 |
| LBH | limb bud and heart development | 0.00602177 |
| SP110 | SP110 nuclear body protein | 0.00602064 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00601567 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | 0.00599704 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00599641 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.00599368 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00599134 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00594721 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00594331 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00592447 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00592201 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00590781 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00590186 |
| CFHR2 | complement factor H-related 2 | 0.00589882 |
| ASTN2 | astrotactin 2 | 0.00589045 |
| CNTN1 | contactin 1 | 0.00588983 |
| MLPH | melanophilin | 0.00587164 |
| MT2A | metallothionein 2A | 0.00587133 |
| ATF5 | activating transcription factor 5 | 0.0058681 |
| G0S2 | G0/G1 switch 2 | 0.00586804 |
| TAC1 | tachykinin, precursor 1 | 0.00584779 |
| LASP1 | LIM and SH3 protein 1 | 0.00583774 |
| C1R | complement component 1, r subcomponent | 0.00583346 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.0058317 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.005826 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00578732 |
| RNASET2 | ribonuclease T2 | 0.0057721 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00577063 |
| FHL1 | four and a half LIM domains 1 | 0.00577001 |
| HEATR1 | HEAT repeat containing 1 | 0.00576996 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00576544 |
| COG7 | component of oligomeric golgi complex 7 | 0.00575744 |
| NCALD | neurocalcin delta | 0.00575112 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00574166 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00573055 |
| BAX | BCL2-associated X protein | 0.00572337 |
| HSPA12A | heat shock 70kDa protein 12A | 0.00572336 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00570486 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00568329 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00567526 |
| PRKD1 | protein kinase D1 | 0.0056679 |
| TMEM47 | transmembrane protein 47 | 0.00566095 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00564255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0254415 |
| POSTN | periostin, osteoblast specific factor | -0.0172291 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.0134761 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0132024 |
| AREG | amphiregulin | -0.0129435 |
| EREG | epiregulin | -0.0120193 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.012013 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0117888 |
| MFAP5 | microfibrillar associated protein 5 | -0.0114066 |
| WT1 | Wilms tumor 1 | -0.0112396 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0111573 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0107727 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0106216 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0103325 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0102799 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0101507 |
| CD9 | CD9 molecule | -0.0100634 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.0100424 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00995391 |
| ASPN | asporin | -0.00993567 |
| PDGFC | platelet derived growth factor C | -0.00992087 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0097007 |
| COL5A2 | collagen, type V, alpha 2 | -0.00964912 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00958155 |
| HOXC6 | homeobox C6 | -0.00951108 |
| MELK | maternal embryonic leucine zipper kinase | -0.00946647 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00945833 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00945684 |
| LRRC15 | leucine rich repeat containing 15 | -0.00918797 |
| ANXA4 | annexin A4 | -0.00911428 |
| EPCAM | epithelial cell adhesion molecule | -0.00909864 |
| DAPK1 | death-associated protein kinase 1 | -0.00896662 |
| MAP7 | microtubule-associated protein 7 | -0.00894505 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00892791 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00874519 |
| TFEC | transcription factor EC | -0.0086321 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00861775 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00855788 |
| HOXC10 | homeobox C10 | -0.00851676 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00849533 |
| SVIL | supervillin | -0.00849419 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00846442 |
| PLS3 | plastin 3 | -0.00844699 |
| COMP | cartilage oligomeric matrix protein | -0.00843275 |
| NVL | nuclear VCP-like | -0.00831785 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0083002 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00829151 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00823141 |
| NPTN | neuroplastin | -0.00816476 |
| MIR22HG | MIR22 host gene | -0.00814503 |
| PKM | pyruvate kinase, muscle | -0.00812827 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00808464 |
| COL10A1 | collagen, type X, alpha 1 | -0.00797598 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00786574 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0078585 |
| RTN2 | reticulon 2 | -0.00785607 |
| YAP1 | Yes-associated protein 1 | -0.00776358 |
| GLS | glutaminase | -0.00776146 |
| HIC2 | hypermethylated in cancer 2 | -0.007684 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00760314 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00749504 |
| ALB | albumin | -0.00747756 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.0074711 |
| ECT2 | epithelial cell transforming 2 | -0.00743281 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00740623 |
| COL5A1 | collagen, type V, alpha 1 | -0.00740319 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00734695 |
| GATA6 | GATA binding protein 6 | -0.00733079 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00732531 |
| CADM1 | cell adhesion molecule 1 | -0.00731874 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00731682 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00731468 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00729075 |
| ATP11B | ATPase, class VI, type 11B | -0.00725691 |
| FN1 | fibronectin 1 | -0.00723316 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.00722476 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0071842 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.007179 |
| KRT17 | keratin 17, type I | -0.00715576 |
| ZNF395 | zinc finger protein 395 | -0.00715061 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.0071493 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00714804 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00714529 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00714441 |
| CDC45 | cell division cycle 45 | -0.00714269 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00711397 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00708403 |
| TES | testin LIM domain protein | -0.00702491 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.0070138 |
| ETNK1 | ethanolamine kinase 1 | -0.00698533 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00697496 |
| FNBP1 | formin binding protein 1 | -0.00693866 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00693784 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00693732 |
| KRT81 | keratin 81, type II | -0.00692431 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00692389 |
| MB | myoglobin | -0.00689668 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00689249 |
| STAG2 | stromal antigen 2 | -0.00685294 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00684742 |
| RNF115 | ring finger protein 115 | -0.00680073 |
| SGMS1 | sphingomyelin synthase 1 | -0.00673448 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00672741 |
| LMNA | lamin A/C | -0.00669648 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00663855 |
| VEGFC | vascular endothelial growth factor C | -0.00662312 |
| APOB | apolipoprotein B | -0.00659443 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00658835 |
| AFP | alpha-fetoprotein | -0.00658464 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00655622 |
| DMXL2 | Dmx-like 2 | -0.00654743 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00653219 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.00652958 |
| H1-2 | H1.2 linker histone, cluster member | -0.00650982 |
| CCNA2 | cyclin A2 | -0.00650496 |
| KRT18 | keratin 18, type I | -0.00648245 |
| PEG3 | paternally expressed 3 | -0.00647922 |
| PMM2 | phosphomannomutase 2 | -0.00643513 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00642924 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00642909 |
| PCP4 | Purkinje cell protein 4 | -0.00642277 |
| FMO5 | flavin containing monooxygenase 5 | -0.00640936 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00635681 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00635333 |
| CKM | creatine kinase, muscle | -0.00635207 |
| CEL | carboxyl ester lipase | -0.00633233 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00633072 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00632098 |
| TG | thyroglobulin | -0.00631748 |
| PLAU | plasminogen activator, urokinase | -0.00630825 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.0062966 |
| SYT1 | synaptotagmin I | -0.00629244 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00629091 |
| CST6 | cystatin E/M | -0.00628841 |
| GPR183 | G protein-coupled receptor 183 | -0.00628533 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00624555 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00624153 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00622848 |
| PMP22 | peripheral myelin protein 22 | -0.00622267 |
| REEP5 | receptor accessory protein 5 | -0.00621075 |
| STK26 | serine/threonine protein kinase 26 | -0.00616458 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) | -0.00616195 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.00615859 |
| AHSG | alpha-2-HS-glycoprotein | -0.00614096 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00612392 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00612282 |
| CTSV | cathepsin V | -0.0061181 |
| THBS2 | thrombospondin 2 | -0.00611201 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00611044 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00610411 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00607338 |
| IL32 | interleukin 32 | -0.006072 |
| PERP | PERP, TP53 apoptosis effector | -0.00602963 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00602029 |
| CD84 | CD84 molecule | -0.00601009 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00599403 |
| TTN | titin | -0.00598265 |
| FST | follistatin | -0.00598143 |
| TUFT1 | tuftelin 1 | -0.00597334 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00595301 |
| FOXE1 | forkhead box E1 | -0.0059484 |
| UBE3C | ubiquitin protein ligase E3C | -0.00593034 |
| NOTCH2 | notch 2 | -0.00592358 |
| MMP11 | matrix metallopeptidase 11 | -0.00592178 |
| RAB32 | RAB32, member RAS oncogene family | -0.00592061 |
| CTSK | cathepsin K | -0.00591344 |
| KRT7 | keratin 7, type II | -0.00589156 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00585849 |
| KIF5B | kinesin family member 5B | -0.00582187 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00581719 |
| CLDN1 | claudin 1 | -0.0057979 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.00578609 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0057633 |
| SDC2 | syndecan 2 | -0.00574812 |
| THPO | thrombopoietin | -0.00574809 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.00573466 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.00572911 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00572388 |
| KMT5B | lysine methyltransferase 5B | -0.00571612 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00570704 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00570421 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00568917 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00566063 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.00565811 |
| GPATCH2 | G patch domain containing 2 | -0.00564619 |
| PRR16 | proline rich 16 | -0.00564561 |
| SEC24D | SEC24 family member D | -0.00564318 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00563077 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.005616 |
| NOTCH2NL | notch 2 N-terminal like | -0.00561579 |
| KLHL41 | kelch-like family member 41 | -0.00560202 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00558691 |
| GAS1 | growth arrest-specific 1 | -0.00557108 |
| PPL | periplakin | -0.00555788 |
| CCDC92 | coiled-coil domain containing 92 | -0.0055505 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00554571 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.00554252 |
| SHTN1 | shootin 1 | -0.00553574 |
| HOMER3 | homer scaffolding protein 3 | -0.0055283 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.00552136 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | -0.00548759 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00548653 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00548445 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.0054722 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.00547154 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00546961 |
| TPP2 | tripeptidyl peptidase II | -0.00546581 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00546195 |
| CD164 | CD164 molecule, sialomucin | -0.00544234 |
| RECQL | RecQ helicase-like | -0.00543934 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00542716 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.00539477 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00539323 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00539033 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00538527 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00537296 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00537293 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00536419 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00534262 |
| ATP13A3 | ATPase type 13A3 | -0.00533222 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00532893 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00532395 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0053233 |
| SDC4 | syndecan 4 | -0.00532148 |
| PDE8A | phosphodiesterase 8A | -0.00530336 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00529433 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00529383 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.00528881 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00528552 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00527616 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00527001 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00526622 |
| MED17 | mediator complex subunit 17 | -0.0052631 |
| RAB38 | RAB38, member RAS oncogene family | -0.00525883 |
| IGSF1 | immunoglobulin superfamily, member 1 | -0.00525538 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.00524876 |
| PBK | PDZ binding kinase | -0.00523287 |
| EGR2 | early growth response 2 | -0.00521881 |
| EMP1 | epithelial membrane protein 1 | -0.0052076 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00520748 |
| SIRT3 | sirtuin 3 | -0.00520174 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00519988 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.0051918 |
| MMP2 | matrix metallopeptidase 2 | -0.00518909 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00518612 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00518542 |
| CERS2 | ceramide synthase 2 | -0.00517259 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00516336 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00516286 |
