LRIG3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description leucine-rich repeats and immunoglobulin-like domains 3| (NCBI Entrez Gene Database, 121227)
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Genes

315 genes differentially expressed following the LRIG3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TLE6 transducin-like enhancer of split 6 2.84844
CD209 CD209 molecule 2.84844
NXPH4 neurexophilin 4 2.84844
GPR151 G protein-coupled receptor 151 2.84844
SSTR1 somatostatin receptor 1 2.84844
IL5RA interleukin 5 receptor, alpha 2.84844
CLEC19A C-type lectin domain family 19, member A 2.84844
UMOD uromodulin 2.84844
CXORF65 chromosome X open reading frame 65 2.84844
SKOR1 SKI family transcriptional corepressor 1 2.84844
SCGN secretagogin, EF-hand calcium binding protein 2.84844
USP26 ubiquitin specific peptidase 26 2.84844
FAM167A family with sequence similarity 167, member A 2.84844
PCDHA7 protocadherin alpha 7 2.84844
RLBP1 retinaldehyde binding protein 1 2.84844
CPED1 cadherin-like and PC-esterase domain containing 1 2.84844
FPR2 formyl peptide receptor 2 2.84844
TBX20 T-box 20 2.84844
TAOK1 TAO kinase 1 2.84844
TMPRSS11D transmembrane protease, serine 11D 2.84844
TMPRSS11A transmembrane protease, serine 11A 2.84844
VTN vitronectin 2.84844
TKTL1 transketolase-like 1 2.84844
DMRTC1B DMRT-like family C1B 2.84844
SFTPB surfactant protein B 2.84844
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.84844
RPL3L ribosomal protein L3-like 2.84844
SPNS2 spinster homolog 2 (Drosophila) 2.84844
RGPD3 RANBP2-like and GRIP domain containing 3 2.84844
CRH corticotropin releasing hormone 2.84844
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.84844
SP6 Sp6 transcription factor 2.84844
C2ORF78 chromosome 2 open reading frame 78 2.84844
ADAMTSL5 ADAMTS-like 5 2.84844
GFI1 growth factor independent 1 transcription repressor 2.84844
ALPK2 alpha-kinase 2 2.84844
CEP295NL CEP295 N-terminal like 2.84844
ASB17 ankyrin repeat and SOCS box containing 17 2.84844
NFAM1 NFAT activating protein with ITAM motif 1 2.84844
TUBB8 tubulin, beta 8 class VIII 2.84844
SSTR3 somatostatin receptor 3 2.84844
TAS2R1 taste receptor, type 2, member 1 2.84844
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 2.84844
GYPB glycophorin B (MNS blood group) 2.84844
GPR20 G protein-coupled receptor 20 2.84844
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.84844
SPATA31G1 SPATA31 subfamily G member 1 2.84844
HTD2 hydroxyacyl-thioester dehydratase type 2 2.84844
CCDC9B coiled-coil domain containing 9B 2.84844
H1-6 H1.6 linker histone, cluster member 2.84844
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.84844
GPR35 G protein-coupled receptor 35 2.84844
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.84844
FRG2C FSHD region gene 2 family, member C 2.84844
FMO2 flavin containing monooxygenase 2 (non-functional) 2.84844
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.84844
TMEM271 transmembrane protein 271 2.84844
TBXT T-box transcription factor T 2.84844
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.84844
TEX53 testis expressed 53 2.84844
LINC02268 long intergenic non-protein coding RNA 2268 2.84844
NOTCH2NLB notch 2 N-terminal like B 2.84844
CIMAP1B ciliary microtubule associated protein 1B 2.84844
EZHIP EZH inhibitory protein 2.84844
SEPTIN12 septin 12 2.84844
MAJIN membrane anchored junction protein 2.84844
CATSPERZ catsper channel auxiliary subunit zeta 2.84844
PCARE photoreceptor cilium actin regulator 2.84844
TMEM40 transmembrane protein 40 2.84844
SPATA25 spermatogenesis associated 25 2.84844
TACSTD2 tumor-associated calcium signal transducer 2 2.84844
SCRT2 scratch family zinc finger 2 2.84844
CXCL16 chemokine (C-X-C motif) ligand 16 2.84844
MSX2 msh homeobox 2 2.84844
MSX1 msh homeobox 1 2.84844
TMEM236 transmembrane protein 236 2.84844
C3ORF80 chromosome 3 open reading frame 80 2.84844
CCNG2 cyclin G2 2.84844
AMBN ameloblastin (enamel matrix protein) 2.84844
HAPLN2 hyaluronan and proteoglycan link protein 2 2.84844
SLC45A2 solute carrier family 45, member 2 2.84844
SLAMF1 signaling lymphocytic activation molecule family member 1 2.84844
DYNLRB2 dynein, light chain, roadblock-type 2 2.84844
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.84844
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.84844
HNF1A HNF1 homeobox A 2.84844
SOAT2 sterol O-acyltransferase 2 2.84844
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.84844
SAA1 serum amyloid A1 2.84844
OR2L2 olfactory receptor, family 2, subfamily L, member 2 2.84844
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 2.84844
IRF5 interferon regulatory factor 5 2.84844
HES2 hes family bHLH transcription factor 2 2.84844
MRLN myoregulin 2.84844
CPA3 carboxypeptidase A3 (mast cell) 2.84844
MAB21L3 mab-21-like 3 (C. elegans) 2.84844
ISL2 ISL LIM homeobox 2 2.84844
CER1 cerberus 1, DAN family BMP antagonist 2.84844
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2.84844
COPS2 COP9 signalosome subunit 2 2.84844
UTS2R urotensin 2 receptor 2.84844
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.84844
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 2.84844
OCM oncomodulin 2.84844
HPX hemopexin 2.84844
GOLGA6B golgin A6 family, member B 2.84844
EDN2 endothelin 2 2.84844
EDN3 endothelin 3 2.84844
KLHL1 kelch-like family member 1 2.84844
C11ORF96 chromosome 11 open reading frame 96 2.84844
ADORA3 adenosine A3 receptor 2.84844
S100Z S100 calcium binding protein Z 2.84844
ANKRD63 ankyrin repeat domain 63 2.84844
CDHR5 cadherin-related family member 5 2.84844
PRAMEF12 PRAME family member 12 2.84844
TBC1D10C TBC1 domain family, member 10C 2.84844
LY96 lymphocyte antigen 96 2.84844
ZC3H12D zinc finger CCCH-type containing 12D 2.84844
PHGR1 proline/histidine/glycine-rich 1 2.84844
GFY golgi-associated, olfactory signaling regulator 2.84844
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.84844
DRC1 dynein regulatory complex subunit 1 2.84844
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.84844
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.84844
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.84844
KRTAP2-3 keratin associated protein 2-3 2.84844
CFI complement factor I 2.84844
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.84844
PSG9 pregnancy specific beta-1-glycoprotein 9 2.84844
CTRB1 chymotrypsinogen B1 2.84844
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.84844
DMRT3 doublesex and mab-3 related transcription factor 3 2.84844
GSTA1 glutathione S-transferase alpha 1 2.84844
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 2.84844
CRHBP corticotropin releasing hormone binding protein 2.84844
VAV1 vav 1 guanine nucleotide exchange factor 2.84844
PRH2 proline-rich protein HaeIII subfamily 2 2.84844
CA5A carbonic anhydrase VA, mitochondrial 2.84844
PGR progesterone receptor 2.84844
LHX9 LIM homeobox 9 2.84844
C11ORF91 chromosome 11 open reading frame 91 2.84844
TEKT4 tektin 4 2.84844
PRSS54 protease, serine, 54 2.84844
ZNF648 zinc finger protein 648 2.84844
LHX2 LIM homeobox 2 2.84844
GREM1 gremlin 1, DAN family BMP antagonist 2.84844
DMTN dematin actin binding protein 2.84844
DDN dendrin 2.84844
EPX eosinophil peroxidase 2.84844
EPO erythropoietin 2.84844
ARGFX arginine-fifty homeobox 2.84844
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.84844
DMRTC1 DMRT-like family C1 2.84844
PTCRA pre T-cell antigen receptor alpha 2.84844
AMER2 APC membrane recruitment protein 2 2.84844
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.84844
USP34 ubiquitin specific peptidase 34 2.84844
APOL3 apolipoprotein L, 3 2.84844
GPR50 G protein-coupled receptor 50 2.84844
GCM1 glial cells missing homolog 1 (Drosophila) 2.84844
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 2.84844
ADAM29 ADAM metallopeptidase domain 29 2.84844
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.84844
CCL25 chemokine (C-C motif) ligand 25 2.84844
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.84844
FAM9C family with sequence similarity 9, member C 2.84844
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.84844
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.84844
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.84844
TWIST1 twist family bHLH transcription factor 1 2.84844
PLA2G4E phospholipase A2, group IVE 2.84844
GRM6 glutamate receptor, metabotropic 6 2.84844
ACADL acyl-CoA dehydrogenase, long chain 2.84844
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.80854
CFAP90 cilia and flagella associated protein 90 2.7169
PCDHB12 protocadherin beta 12 2.7169
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.50279
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.42527
ZNF608 zinc finger protein 608 2.424
ALAS2 5'-aminolevulinate synthase 2 2.41363
HARBI1 harbinger transposase derived 1 2.38731
FMO1 flavin containing monooxygenase 1 2.34579
CFAP47 cilia and flagella associated protein 47 2.33014
CETN2 centrin, EF-hand protein, 2 2.32988
C3ORF70 chromosome 3 open reading frame 70 2.31731
CSNK2A1 casein kinase 2, alpha 1 polypeptide 2.29035
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 2.2814
AEBP1 AE binding protein 1 2.28085
TK1 thymidine kinase 1, soluble 2.27348
NCMAP noncompact myelin associated protein 2.27348
SCGB2B2 secretoglobin, family 2B, member 2 2.24412
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.23654
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 2.23653
TIPE3 TNF alpha induced protein 8 like 3 2.21669
EXO1 exonuclease 1 2.16783
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 2.0973
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.08978
TNNT2 troponin T type 2 (cardiac) 2.08568
CCDC107 coiled-coil domain containing 107 2.08568
PTMA prothymosin, alpha 2.08134
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.06089
STC2 stanniocalcin 2 2.05545
SLC35E2B solute carrier family 35, member E2B 2.05545
ZNF850 zinc finger protein 850 2.01611
ZNF160 zinc finger protein 160 2.00547

decreased expression

Symbol Name Standardized Value
SLC46A3 solute carrier family 46, member 3 -2.84844
IL15RA interleukin 15 receptor, alpha -2.84844
COL25A1 collagen, type XXV, alpha 1 -2.84844
ACHE acetylcholinesterase (Yt blood group) -2.84844
GRM2 glutamate receptor, metabotropic 2 -2.84844
NFE2 nuclear factor, erythroid 2 -2.84844
VPREB3 pre-B lymphocyte 3 -2.84844
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.84844
ALG10 ALG10, alpha-1,2-glucosyltransferase -2.84844
GDA guanine deaminase -2.84844
SYCP2 synaptonemal complex protein 2 -2.84844
SERTM1 serine-rich and transmembrane domain containing 1 -2.84844
OVGP1 oviductal glycoprotein 1, 120kDa -2.84844
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 -2.84844
RASL10B RAS-like, family 10, member B -2.84844
ZNF284 zinc finger protein 284 -2.84844
LYNX1 Ly6/neurotoxin 1 -2.84844
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 -2.84844
SCRG1 stimulator of chondrogenesis 1 -2.84844
CA7 carbonic anhydrase VII -2.84844
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.84844
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.84844
AMDHD1 amidohydrolase domain containing 1 -2.84844
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma -2.84844
C20ORF204 chromosome 20 open reading frame 204 -2.84844
RUMY3 RUMY family member 3 -2.84844
SLC45A1 solute carrier family 45, member 1 -2.84844
CNTN6 contactin 6 -2.84844
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 -2.84844
F5 coagulation factor V (proaccelerin, labile factor) -2.84844
ALX4 ALX homeobox 4 -2.84844
ARID1B AT rich interactive domain 1B (SWI1-like) -2.84844
CCDC198 coiled-coil domain containing 198 -2.84844
ESPNL espin-like -2.84844
VXN vexin -2.84844
SBSN suprabasin -2.84844
PCDHGA2 protocadherin gamma subfamily A, 2 -2.84844
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -2.84844
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.84844
DES desmin -2.84844
CLDN9 claudin 9 -2.84844
NPHP1 nephronophthisis 1 (juvenile) -2.84844
BTNL2 butyrophilin-like 2 -2.84844
PRRT1 proline-rich transmembrane protein 1 -2.84844
CATSPERQ catsper channel auxiliary subunit theta -2.84844
LMNTD2 lamin tail domain containing 2 -2.84844
DLG2 discs, large homolog 2 (Drosophila) -2.82764
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 -2.81488
TMEM79 transmembrane protein 79 -2.81488
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.80401
SPACA6 sperm acrosome associated 6 -2.78622
IL13RA1 interleukin 13 receptor, alpha 1 -2.78622
MMP11 matrix metallopeptidase 11 -2.73396
TMEM63A transmembrane protein 63A -2.71433
CUL9 cullin 9 -2.70128
RPS6 ribosomal protein S6 -2.62109
DEGS2 delta(4)-desaturase, sphingolipid 2 -2.6204
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase -2.61915
BCAN brevican -2.61915
ANO1 anoctamin 1, calcium activated chloride channel -2.5947
TMEM145 transmembrane protein 145 -2.59184
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -2.58702
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.5649
PGD phosphogluconate dehydrogenase -2.52371
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -2.4955
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.48918
MARK2 MAP/microtubule affinity-regulating kinase 2 -2.44227
ASPH aspartate beta-hydroxylase -2.41976
VAMP8 vesicle-associated membrane protein 8 -2.37739
PTPRG protein tyrosine phosphatase, receptor type, G -2.35439
DPY19L3 dpy-19-like 3 (C. elegans) -2.34579
NXPH1 neurexophilin 1 -2.30627
ZNF423 zinc finger protein 423 -2.29791
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 -2.29657
COL28A1 collagen, type XXVIII, alpha 1 -2.29657
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.29175
CYFIP2 cytoplasmic FMR1 interacting protein 2 -2.29175
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -2.27348
DDIT4L DNA-damage-inducible transcript 4-like -2.27209
HABP4 hyaluronan binding protein 4 -2.25642
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -2.24832
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -2.24274
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.23653
FYB2 FYN binding protein 2 -2.23653
FAT2 FAT atypical cadherin 2 -2.23637
PLA2G10 phospholipase A2, group X -2.23637
TMEM203 transmembrane protein 203 -2.22993
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -2.20728
RGS20 regulator of G-protein signaling 20 -2.20702
BPHL biphenyl hydrolase-like (serine hydrolase) -2.18708
CDC7 cell division cycle 7 -2.17209
CD24 CD24 molecule -2.17209
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.17209
TMEM106A transmembrane protein 106A -2.15504
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -2.14966
SH2B2 SH2B adaptor protein 2 -2.14966
NHLRC3 NHL repeat containing 3 -2.11006
EGFLAM EGF-like, fibronectin type III and laminin G domains -2.10577
HOOK2 hook microtubule-tethering protein 2 -2.08568
SCAMP3 secretory carrier membrane protein 3 -2.0831
ZNF615 zinc finger protein 615 -2.06783
HMGA1 high mobility group AT-hook 1 -2.06634
SIT1 signaling threshold regulating transmembrane adaptor 1 -2.06089
ZCCHC8 zinc finger, CCHC domain containing 8 -2.03637
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) -2.03301
PKD1L3 polycystic kidney disease 1-like 3 -2.02194
ZNF277 zinc finger protein 277 -2.02194
VEPH1 ventricular zone expressed PH domain-containing 1 -2.01611
PRRT2 proline-rich transmembrane protein 2 -2.00547
TERF2 telomeric repeat binding factor 2 -2.00388