| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | low density lipoprotein receptor-related protein 6|This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 4040) |
| External Link | https://ncbi.nlm.nih.gov/gene/4040 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the LRP6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRAGA | Ras-related GTP binding A | 0.0204463 |
| PROM1 | prominin 1 | 0.0187938 |
| PLIN2 | perilipin 2 | 0.0165914 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0160153 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0146225 |
| MAGEA3 | melanoma antigen family A3 | 0.0131762 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0130759 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0126056 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.012383 |
| TXLNA | taxilin alpha | 0.0121758 |
| TSPYL5 | TSPY-like 5 | 0.0120493 |
| NOTCH2NL | notch 2 N-terminal like | 0.0119279 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0118046 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0110437 |
| OXTR | oxytocin receptor | 0.0106651 |
| TOB1 | transducer of ERBB2, 1 | 0.0103037 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.0103011 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.0102755 |
| PIP | prolactin-induced protein | 0.0102454 |
| KRT23 | keratin 23, type I | 0.0101489 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00998603 |
| PRAME | preferentially expressed antigen in melanoma | 0.00989816 |
| HMOX1 | heme oxygenase 1 | 0.00979116 |
| IRS2 | insulin receptor substrate 2 | 0.00976076 |
| NCALD | neurocalcin delta | 0.00955156 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00949894 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00948039 |
| NAV2 | neuron navigator 2 | 0.00947957 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00945405 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.0094481 |
| EGR1 | early growth response 1 | 0.00939606 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00933811 |
| MMP1 | matrix metallopeptidase 1 | 0.00929281 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00924084 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00887496 |
| IER5 | immediate early response 5 | 0.00871886 |
| CLGN | calmegin | 0.00869528 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00868222 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00863483 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00855343 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00852488 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00848833 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00847086 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00847069 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00841477 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00835155 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00829963 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00829866 |
| RANBP6 | RAN binding protein 6 | 0.0082521 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00822592 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00822134 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00817731 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00814441 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00811727 |
| RCAN1 | regulator of calcineurin 1 | 0.00808218 |
| RRAGD | Ras-related GTP binding D | 0.00798914 |
| COBL | cordon-bleu WH2 repeat protein | 0.00797626 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0079746 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00795402 |
| IQCG | IQ motif containing G | 0.00795122 |
| HOXD1 | homeobox D1 | 0.00794285 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00792842 |
| SNX11 | sorting nexin 11 | 0.00789375 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0078573 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00784874 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.00782002 |
| BCL2A1 | BCL2-related protein A1 | 0.00780392 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00777926 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00775093 |
| ZNF160 | zinc finger protein 160 | 0.00771844 |
| NFIB | nuclear factor I/B | 0.00767867 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00767309 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00762978 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0076085 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00760632 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00759116 |
| KLHL24 | kelch-like family member 24 | 0.0075907 |
| ZNF721 | zinc finger protein 721 | 0.00754654 |
| MT1E | metallothionein 1E | 0.00753199 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00752652 |
| CEP170 | centrosomal protein 170kDa | 0.00745767 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00745019 |
| PTK2 | protein tyrosine kinase 2 | 0.00743944 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00743442 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00742648 |
| GLA | galactosidase, alpha | 0.00741581 |
| IL6R | interleukin 6 receptor | 0.00738025 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00737944 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00736488 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00736417 |
| KRT14 | keratin 14, type I | 0.00736331 |
| SEPHS2 | selenophosphate synthetase 2 | 0.00736139 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00735717 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00732301 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00729633 |
| RUNX3 | runt-related transcription factor 3 | 0.00728654 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00728228 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00727877 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00727309 |
| PXDC1 | PX domain containing 1 | 0.00722406 |
| MAP7 | microtubule-associated protein 7 | 0.00722214 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00721593 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00719602 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00714827 |
| GRAMD2B | GRAM domain containing 2B | 0.00714234 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00714226 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00710556 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0071051 |
| ASS1 | argininosuccinate synthase 1 | 0.00710144 |
| MAGEA12 | melanoma antigen family A12 | 0.007083 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00707874 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00707779 |
| TPP1 | tripeptidyl peptidase I | 0.00707372 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00706894 |
| NNMT | nicotinamide N-methyltransferase | 0.00706111 |
| KMT5B | lysine methyltransferase 5B | 0.00703604 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00702651 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00699775 |
| STXBP2 | syntaxin binding protein 2 | 0.00698695 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00693559 |
| APOD | apolipoprotein D | 0.00692335 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00691001 |
| MAOB | monoamine oxidase B | 0.00690235 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0068962 |
| KLK11 | kallikrein-related peptidase 11 | 0.00688786 |
| MYO6 | myosin VI | 0.00688632 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00687332 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00686785 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00681342 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00680551 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00677961 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00675136 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00672629 |
| MVP | major vault protein | 0.00671517 |
| USP3 | ubiquitin specific peptidase 3 | 0.00669693 |
| BBX | bobby sox homolog (Drosophila) | 0.00669251 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00668389 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00668084 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00667609 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00665824 |
| GPX7 | glutathione peroxidase 7 | 0.00663156 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00663016 |
| MOK | MOK protein kinase | 0.00655347 |
| TOB2 | transducer of ERBB2, 2 | 0.00654774 |
| WT1 | Wilms tumor 1 | 0.006544 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00653343 |
| IRX5 | iroquois homeobox 5 | 0.0065137 |
| PUM3 | pumilio RNA binding family member 3 | 0.00650744 |
| RPS27L | ribosomal protein S27-like | 0.00647741 |
| THBS1 | thrombospondin 1 | 0.00647451 |
| CST1 | cystatin SN | 0.00645061 |
| KLK7 | kallikrein-related peptidase 7 | 0.00644656 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0064369 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00643274 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00640961 |
| INHBA | inhibin, beta A | 0.00638967 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.00638145 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00636165 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00635209 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00634869 |
| DCT | dopachrome tautomerase | 0.0063425 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00634248 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00633952 |
| UBAP2 | ubiquitin associated protein 2 | 0.0063244 |
| RAB29 | RAB29, member RAS oncogene family | 0.00631677 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00631241 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00630306 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00629952 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0062962 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | 0.00627559 |
| HOXC6 | homeobox C6 | 0.00624298 |
| AXL | AXL receptor tyrosine kinase | 0.00624292 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00623439 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00622525 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00621552 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0062078 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00618178 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00617959 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00617502 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00616716 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00612542 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00612365 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00612333 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0061128 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00610865 |
| RUNX1 | runt-related transcription factor 1 | 0.0061084 |
| ITSN2 | intersectin 2 | 0.00610784 |
| OAT | ornithine aminotransferase | 0.00609282 |
| RANBP2 | RAN binding protein 2 | 0.00607077 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00606938 |
| PLK2 | polo-like kinase 2 | 0.00605395 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00603091 |
| PITX3 | paired-like homeodomain 3 | 0.00602119 |
| SPATA20 | spermatogenesis associated 20 | 0.00599361 |
| EFHD1 | EF-hand domain family, member D1 | 0.00598454 |
| KRT7 | keratin 7, type II | 0.00595212 |
| PRTN3 | proteinase 3 | 0.00592977 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00592975 |
| SNF8 | SNF8, ESCRT-II complex subunit | 0.00592715 |
| CLDN3 | claudin 3 | 0.00592031 |
| MT1X | metallothionein 1X | 0.00591147 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00589729 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00588245 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00587973 |
| DUSP6 | dual specificity phosphatase 6 | 0.00587654 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00587027 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00586022 |
| MUC16 | mucin 16, cell surface associated | 0.00584504 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00583323 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00582545 |
| CFB | complement factor B | 0.00581027 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00580699 |
| PNN | pinin, desmosome associated protein | 0.00580643 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00580197 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00579199 |
| ODAM | odontogenic, ameloblast asssociated | 0.00578171 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0057761 |
| ITGAV | integrin, alpha V | 0.00576956 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00576272 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00574185 |
| REPIN1 | replication initiator 1 | 0.00573168 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.00573033 |
| CAPN3 | calpain 3, (p94) | 0.00571821 |
| NDE1 | nudE neurodevelopment protein 1 | 0.00571309 |
| TMEM63A | transmembrane protein 63A | 0.00571171 |
| CES3 | carboxylesterase 3 | 0.0057109 |
| CTSD | cathepsin D | 0.0057098 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.0057027 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00570197 |
| ASTN2 | astrotactin 2 | 0.00569943 |
| SGCE | sarcoglycan, epsilon | 0.00568612 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00566819 |
| HP | haptoglobin | 0.00566267 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00566173 |
| BRD2 | bromodomain containing 2 | 0.00565756 |
| ASRGL1 | asparaginase like 1 | 0.00565637 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 0.00565379 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00563917 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0056313 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00562493 |
| JMJD6 | jumonji domain containing 6 | 0.00560331 |
| ZNF224 | zinc finger protein 224 | 0.00559609 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00557508 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00557279 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00557157 |
| PLXND1 | plexin D1 | 0.00556349 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00556267 |
| KLHDC10 | kelch domain containing 10 | 0.00556112 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0308269 |
| S100P | S100 calcium binding protein P | -0.021107 |
| HOPX | HOP homeobox | -0.0186679 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0164932 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0154255 |
| NELL2 | NEL-like 2 (chicken) | -0.0148361 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0146074 |
| KRT13 | keratin 13, type I | -0.0142731 |
| DES | desmin | -0.0135546 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0132985 |
| FHL1 | four and a half LIM domains 1 | -0.0132755 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0126509 |
| PLBD1 | phospholipase B domain containing 1 | -0.0124835 |
| A2M | alpha-2-macroglobulin | -0.0120604 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0115878 |
| PITX1 | paired-like homeodomain 1 | -0.0112863 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0112494 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0109744 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0109243 |
| COPS7A | COP9 signalosome subunit 7A | -0.0107121 |
| FBLN1 | fibulin 1 | -0.0107032 |
| CD99 | CD99 molecule | -0.0106893 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0106404 |
| SPRR3 | small proline-rich protein 3 | -0.0106043 |
| PLN | phospholamban | -0.0105918 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.0105616 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.010465 |
| KRT6A | keratin 6A, type II | -0.0104403 |
| PRDX2 | peroxiredoxin 2 | -0.0101347 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.010132 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0100514 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.0100075 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00979421 |
| C1R | complement component 1, r subcomponent | -0.00969015 |
| CHRDL1 | chordin-like 1 | -0.00961476 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00954654 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00932798 |
| FRZB | frizzled-related protein | -0.00924113 |
| S100A7 | S100 calcium binding protein A7 | -0.00923956 |
| LYZ | lysozyme | -0.00921888 |
| SYNGR3 | synaptogyrin 3 | -0.00919895 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00915906 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00912738 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00910802 |
| TNNC1 | troponin C type 1 (slow) | -0.00903435 |
| TSPAN1 | tetraspanin 1 | -0.00892535 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00889912 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.0088272 |
| LDB3 | LIM domain binding 3 | -0.00872849 |
| C7 | complement component 7 | -0.00869412 |
| S100A8 | S100 calcium binding protein A8 | -0.0085913 |
| TPM4 | tropomyosin 4 | -0.00852307 |
| COLEC12 | collectin sub-family member 12 | -0.00844196 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00832071 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00832003 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00831952 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.0082999 |
| ACP3 | acid phosphatase 3 | -0.00828739 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00827671 |
| S100A9 | S100 calcium binding protein A9 | -0.00826149 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00824502 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00824468 |
| RCAN2 | regulator of calcineurin 2 | -0.00824389 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00824025 |
| SPRR1B | small proline-rich protein 1B | -0.00819151 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00818606 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00817395 |
| NELL1 | NEL-like 1 (chicken) | -0.00816177 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00812678 |
| COMMD10 | COMM domain containing 10 | -0.00806419 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00806396 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00798983 |
| CD52 | CD52 molecule | -0.00793064 |
| HBB | hemoglobin, beta | -0.0079157 |
| BLNK | B-cell linker | -0.00788877 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00784957 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00779851 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00778232 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00777992 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0077241 |
| RETREG1 | reticulophagy regulator 1 | -0.0077203 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00769436 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00768904 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00767264 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00766552 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00765616 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00761638 |
| CCND2 | cyclin D2 | -0.00759778 |
| DENND1B | DENN/MADD domain containing 1B | -0.00757145 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | -0.00756195 |
| CLCA2 | chloride channel accessory 2 | -0.00755341 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00755162 |
| MYOT | myotilin | -0.00754231 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00754177 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00749734 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00748572 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00745452 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00745144 |
| DCN | decorin | -0.00742689 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00742188 |
| TTN | titin | -0.00741654 |
| SELENBP1 | selenium binding protein 1 | -0.00734744 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00734533 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00730987 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.0072975 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.00729543 |
| CFD | complement factor D (adipsin) | -0.00725276 |
| MB | myoglobin | -0.00721702 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00718663 |
| MMP12 | matrix metallopeptidase 12 | -0.00717027 |
| TNNC2 | troponin C type 2 (fast) | -0.00714109 |
| RPS5 | ribosomal protein S5 | -0.0071015 |
| CHKB | choline kinase beta | -0.00709427 |
| DSTN | destrin (actin depolymerizing factor) | -0.00706182 |
| G0S2 | G0/G1 switch 2 | -0.00704025 |
| OLFM4 | olfactomedin 4 | -0.00703687 |
| SLN | sarcolipin | -0.0070359 |
| PGD | phosphogluconate dehydrogenase | -0.00702554 |
| AURKB | aurora kinase B | -0.0069921 |
| RANBP1 | RAN binding protein 1 | -0.00697837 |
| FAM3C | family with sequence similarity 3, member C | -0.00696401 |
| SLAMF7 | SLAM family member 7 | -0.00695068 |
| ARG2 | arginase 2 | -0.00694078 |
| ITM2A | integral membrane protein 2A | -0.00690867 |
| CNTN1 | contactin 1 | -0.00689253 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00688556 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00688511 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00687871 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00687666 |
| PTN | pleiotrophin | -0.00686508 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | -0.00685654 |
| DUOX2 | dual oxidase 2 | -0.00683978 |
| GPR171 | G protein-coupled receptor 171 | -0.00683414 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00682828 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00680602 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00678565 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00677422 |
| TMEM230 | transmembrane protein 230 | -0.00671675 |
| LIMA1 | LIM domain and actin binding 1 | -0.00671574 |
| PGK1 | phosphoglycerate kinase 1 | -0.00669213 |
| SEPHS1 | selenophosphate synthetase 1 | -0.00666344 |
| TPM3 | tropomyosin 3 | -0.00664599 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | -0.00664223 |
| TCAP | titin-cap | -0.00663697 |
| FLNA | filamin A, alpha | -0.00662823 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0066116 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00656286 |
| NDNF | neuron-derived neurotrophic factor | -0.00654885 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0065424 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | -0.00654077 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00653862 |
| GNLY | granulysin | -0.00652954 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00652906 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00652166 |
| TFDP1 | transcription factor Dp-1 | -0.00649828 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.0064838 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00648361 |
| FGL2 | fibrinogen-like 2 | -0.00648044 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00647221 |
| TCF21 | transcription factor 21 | -0.00646403 |
| CDCA4 | cell division cycle associated 4 | -0.00645697 |
| FOXF2 | forkhead box F2 | -0.0064432 |
| CKM | creatine kinase, muscle | -0.00643625 |
| LDB2 | LIM domain binding 2 | -0.00640729 |
| FAM162A | family with sequence similarity 162, member A | -0.00639534 |
| CFH | complement factor H | -0.00638553 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00637719 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00636282 |
| FZD5 | frizzled class receptor 5 | -0.00634519 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00631874 |
| GPC3 | glypican 3 | -0.00629669 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00626575 |
| PRF1 | perforin 1 (pore forming protein) | -0.00626005 |
| CCNB1 | cyclin B1 | -0.00625587 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00625066 |
| TSPAN13 | tetraspanin 13 | -0.00624238 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0062405 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00622987 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00620286 |
| CPE | carboxypeptidase E | -0.00620019 |
| CCNA2 | cyclin A2 | -0.00618661 |
| PRMT1 | protein arginine methyltransferase 1 | -0.0061716 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00616721 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00616118 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00616018 |
| IVL | involucrin | -0.00615499 |
| MYBPC1 | myosin binding protein C, slow type | -0.00614255 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00613877 |
| SPRR1A | small proline-rich protein 1A | -0.00613283 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0061237 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00611605 |
| ITGB7 | integrin, beta 7 | -0.00611592 |
| CDCA3 | cell division cycle associated 3 | -0.0061126 |
| HK2 | hexokinase 2 | -0.00610838 |
| TSPAN8 | tetraspanin 8 | -0.00610115 |
| S100A2 | S100 calcium binding protein A2 | -0.00609647 |
| CHEK2 | checkpoint kinase 2 | -0.00608462 |
| RRM2 | ribonucleotide reductase M2 | -0.00608447 |
| RHOA | ras homolog family member A | -0.00608038 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00606934 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.0060686 |
| PHB2 | prohibitin 2 | -0.00603034 |
| MPZL2 | myelin protein zero-like 2 | -0.00602689 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00601377 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00599471 |
| NID1 | nidogen 1 | -0.00596646 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00595908 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00594911 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00593384 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00593342 |
| SMAGP | small cell adhesion glycoprotein | -0.005932 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00591743 |
| PYGM | phosphorylase, glycogen, muscle | -0.0059115 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00588759 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00585501 |
| EGR2 | early growth response 2 | -0.0058528 |
| C1S | complement component 1, s subcomponent | -0.00583904 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00583803 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00583728 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00583576 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00583468 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00583271 |
| EPHB4 | EPH receptor B4 | -0.00582855 |
| METRN | meteorin, glial cell differentiation regulator | -0.00582854 |
| BLVRB | biliverdin reductase B | -0.00582575 |
| WDR61 | WD repeat domain 61 | -0.00582348 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00581326 |
| MMP9 | matrix metallopeptidase 9 | -0.00580659 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00580201 |
| NEK7 | NIMA-related kinase 7 | -0.00580134 |
| CALML3 | calmodulin-like 3 | -0.00580078 |
| STOM | stomatin | -0.00579082 |
| CD2 | CD2 molecule | -0.00578904 |
| PDHB | pyruvate dehydrogenase (lipoamide) beta | -0.00578141 |
| INAVA | innate immunity activator | -0.00578022 |
| PADI3 | peptidyl arginine deiminase, type III | -0.0057802 |
| PDE8B | phosphodiesterase 8B | -0.0057734 |
| CLCA4 | chloride channel accessory 4 | -0.00576429 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00575216 |
| ATG5 | autophagy related 5 | -0.00574523 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00574273 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00573935 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00573611 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00573033 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00572087 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -0.00571843 |
| RHOH | ras homolog family member H | -0.00571807 |
| CD209 | CD209 molecule | -0.00570874 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -0.00570324 |
| DSG3 | desmoglein 3 | -0.00569259 |
