LRRK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description leucine-rich repeat kinase 2|This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 120892)
External Link http://www.ncbi.nlm.nih.gov/gene/120892
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Genes

10 substrates of the kinase LRRK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
EZR ezrin
LRRK2 leucine-rich repeat kinase 2
MAPT microtubule-associated protein tau
MSN moesin
RAB5B RAB5B, member RAS oncogene family
RDX radixin
RPS11 ribosomal protein S11
RPS15 ribosomal protein S15
SNAPIN SNAP-associated protein