LS-513 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: colorectal carcinoma (Cell Line Ontology, CLO_0007407)
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Genes

402 genes mutated in the LS-513 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACO1 aconitase 1, soluble
ACOT11 acyl-CoA thioesterase 11
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADAMTSL3 ADAMTS-like 3
ADGRB3 adhesion G protein-coupled receptor B3
ADGRV1 adhesion G protein-coupled receptor V1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRA2C adrenoceptor alpha 2C
AHCTF1 AT hook containing transcription factor 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15B arachidonate 15-lipoxygenase, type B
AMD1 adenosylmethionine decarboxylase 1
AMPH amphiphysin
ANAPC2 anaphase promoting complex subunit 2
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKRD20A20P ankyrin repeat domain 20 family, member A20, pseudogene
ANO5 anoctamin 5
AP4B1 adaptor-related protein complex 4, beta 1 subunit
APOB apolipoprotein B
APOF apolipoprotein F
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP35 Rho GTPase activating protein 35
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATP10B ATPase, class V, type 10B
ATP11B ATPase, class VI, type 11B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRNL1 attractin-like 1
BANP BTG3 associated nuclear protein
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BEND3 BEN domain containing 3
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BOC BOC cell adhesion associated, oncogene regulated
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSN bassoon presynaptic cytomatrix protein
C1QTNF2 C1q and tumor necrosis factor related protein 2
C3 complement component 3
C8A complement component 8, alpha polypeptide
CARD11 caspase recruitment domain family, member 11
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASZ1 castor zinc finger 1
CC2D1A coiled-coil and C2 domain containing 1A
CCRL2 chemokine (C-C motif) receptor-like 2
CDC7 cell division cycle 7
CDH16 cadherin 16, KSP-cadherin
CDH23 cadherin-related 23
CDK13 cyclin-dependent kinase 13
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16
CES3 carboxylesterase 3
CFAP46 cilia and flagella associated protein 46
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD7 chromodomain helicase DNA binding protein 7
CHPF2 chondroitin polymerizing factor 2
CLCN1 chloride channel, voltage-sensitive 1
CLEC3A C-type lectin domain family 3, member A
CLRN1 clarin 1
COL5A1 collagen, type V, alpha 1
COL6A3 collagen, type VI, alpha 3
COPG2 coatomer protein complex, subunit gamma 2
CPE carboxypeptidase E
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAXX death-domain associated protein
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DCX doublecortin
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DLC1 DLC1 Rho GTPase activating protein
DMXL2 Dmx-like 2
DNAH5 dynein, axonemal, heavy chain 5
DOCK1 dedicator of cytokinesis 1
DPP6 dipeptidyl-peptidase 6
DUOX2 dual oxidase 2
EDC4 enhancer of mRNA decapping 4
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EDNRB endothelin receptor type B
EFCAB6 EF-hand calcium binding domain 6
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPPK1 epiplakin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EXD3 exonuclease 3'-5' domain containing 3
EYA1 EYA transcriptional coactivator and phosphatase 1
EYS eyes shut homolog (Drosophila)
FAM124A family with sequence similarity 124A
FAM160A1 family with sequence similarity 160, member A1
FAM160A2 family with sequence similarity 160, member A2
FAM174B family with sequence similarity 174, member B
FAM43A family with sequence similarity 43, member A
FAM92B family with sequence similarity 92, member B
FBN2 fibrillin 2
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FEM1B fem-1 homolog b (C. elegans)
FER fer (fps/fes related) tyrosine kinase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT4 fms-related tyrosine kinase 4
FMO4 flavin containing monooxygenase 4
FOXL1 forkhead box L1
FOXP2 forkhead box P2
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GAP43 growth associated protein 43
GATS GATS, stromal antigen 3 opposite strand
GBA2 glucosidase, beta (bile acid) 2
GJA1 gap junction protein, alpha 1, 43kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA6L2 golgin A6 family-like 2
GOLGA8N golgin A8 family, member N
GORAB golgin, RAB6-interacting
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
GRIK3 glutamate receptor, ionotropic, kainate 3
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GYS1 glycogen synthase 1 (muscle)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HARBI1 harbinger transposase derived 1
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIST1H1C histone cluster 1, H1c
HK3 hexokinase 3 (white cell)
HLA-C major histocompatibility complex, class I, C
HMCN1 hemicentin 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSH2D hematopoietic SH2 domain containing
HSPE1 heat shock 10kDa protein 1
HTT huntingtin
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFT172 intraflagellar transport 172
IGSF3 immunoglobulin superfamily, member 3
IL1R1 interleukin 1 receptor, type I
IL23R interleukin 23 receptor
IMPACT impact RWD domain protein
INTS1 integrator complex subunit 1
IPO8 importin 8
IRAK2 interleukin-1 receptor-associated kinase 2
IRF6 interferon regulatory factor 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPKA inositol-trisphosphate 3-kinase A
JAKMIP2 janus kinase and microtubule interacting protein 2
KARS lysyl-tRNA synthetase
KAT6B K(lysine) acetyltransferase 6B
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIAA0100 KIAA0100
KIAA1671 KIAA1671
KIAA1958 KIAA1958
KIF19 kinesin family member 19
KIF1A kinesin family member 1A
KIF6 kinesin family member 6
KIFC1 kinesin family member C1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRTAP5-2 keratin associated protein 5-2
KSR2 kinase suppressor of ras 2
LAMB4 laminin, beta 4
LARP1 La ribonucleoprotein domain family, member 1
LATS2 large tumor suppressor kinase 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRP11 low density lipoprotein receptor-related protein 11
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LTF lactotransferrin
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP9 microtubule-associated protein 9
MAPK3 mitogen-activated protein kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MBP myelin basic protein
MEP1B meprin A, beta
MEPE matrix extracellular phosphoglycoprotein
MET MET proto-oncogene, receptor tyrosine kinase
METTL17 methyltransferase like 17
MGA MGA, MAX dimerization protein
MICALL2 MICAL-like 2
MINA MYC induced nuclear antigen
MLX MLX, MAX dimerization protein
MMP20 matrix metallopeptidase 20
MMRN1 multimerin 1
MRAP melanocortin 2 receptor accessory protein
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSH4 mutS homolog 4
MST1 macrophage stimulating 1
MTG2 mitochondrial ribosome-associated GTPase 2
MTUS1 microtubule associated tumor suppressor 1
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUSTN1 musculoskeletal, embryonic nuclear protein 1
MUTYH mutY homolog
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYO9A myosin IXA
MYT1 myelin transcription factor 1
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative)
NALCN sodium leak channel, non selective
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
NEB nebulin
NEK10 NIMA-related kinase 10
NEK5 NIMA-related kinase 5
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NLRP2 NLR family, pyrin domain containing 2
NLRP5 NLR family, pyrin domain containing 5
NLRP7 NLR family, pyrin domain containing 7
NOP14 NOP14 nucleolar protein
NOP58 NOP58 ribonucleoprotein
NOTCH4 notch 4
NOX3 NADPH oxidase 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRN1 neuritin 1
NRXN3 neurexin 3
NTF4 neurotrophin 4
NUP133 nucleoporin 133kDa
NWD2 NACHT and WD repeat domain containing 2
NXPH1 neurexophilin 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OBSL1 obscurin-like 1
OR10G8 olfactory receptor, family 10, subfamily G, member 8
OR2Z1 olfactory receptor, family 2, subfamily Z, member 1
OR4D5 olfactory receptor, family 4, subfamily D, member 5
OR4K17 olfactory receptor, family 4, subfamily K, member 17
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR6C65 olfactory receptor, family 6, subfamily C, member 65
OR7G2 olfactory receptor, family 7, subfamily G, member 2
OR8H2 olfactory receptor, family 8, subfamily H, member 2
OR8H3 olfactory receptor, family 8, subfamily H, member 3
OR9A2 olfactory receptor, family 9, subfamily A, member 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PAX6 paired box 6
PCDH10 protocadherin 10
PCDH17 protocadherin 17
PCDHG@ protocadherin gamma cluster
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA2 protocadherin gamma subfamily A, 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE4B phosphodiesterase 4B, cAMP-specific
PDZD2 PDZ domain containing 2
PER1 period circadian clock 1
PER3 period circadian clock 3
PGK2 phosphoglycerate kinase 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP2 plakophilin 2
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLG plasminogen
PLXND1 plexin D1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLRMT polymerase (RNA) mitochondrial (DNA directed)
POTED POTE ankyrin domain family, member D
POTEG POTE ankyrin domain family, member G
POU6F2 POU class 6 homeobox 2
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PQLC1 PQ loop repeat containing 1
PRADC1 protease-associated domain containing 1
PRDM9 PR domain containing 9
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKG2 protein kinase, cGMP-dependent, type II
PRSS57 protease, serine, 57
PRTFDC1 phosphoribosyl transferase domain containing 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
PTPRK protein tyrosine phosphatase, receptor type, K
RAD54L RAD54-like (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGDS ral guanine nucleotide dissociation stimulator
RANBP2 RAN binding protein 2
RASA2 RAS p21 protein activator 2
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RBM25 RNA binding motif protein 25
RBMS2 RNA binding motif, single stranded interacting protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RHPN2 rhophilin, Rho GTPase binding protein 2
RIC8A RIC8 guanine nucleotide exchange factor A
RIF1 replication timing regulatory factor 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RYR2 ryanodine receptor 2 (cardiac)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDK1 sidekick cell adhesion molecule 1
SEC31A SEC31 homolog A (S. cerevisiae)
SENP5 SUMO1/sentrin specific peptidase 5
SEPT14 septin 14
SEPT2 septin 2
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFMBT1 Scm-like with four mbt domains 1
SFRP4 secreted frizzled-related protein 4
SH3PXD2A SH3 and PX domains 2A
SHCBP1L SHC SH2-domain binding protein 1-like
SHH sonic hedgehog
SIK3 SIK family kinase 3
SIRT3 sirtuin 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLIT2 slit homolog 2 (Drosophila)
SLITRK2 SLIT and NTRK-like family, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC5 structural maintenance of chromosomes 5
SNRPG small nuclear ribonucleoprotein polypeptide G
SNTG1 syntrophin, gamma 1
SP100 SP100 nuclear antigen
SPATA31D1 SPATA31 subfamily D, member 1
SPATA31D4 SPATA31 subfamily D, member 4
SPDYE1 speedy/RINGO cell cycle regulator family member E1
SRRM2 serine/arginine repetitive matrix 2
STK31 serine/threonine kinase 31
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUSD5 sushi domain containing 5
SYNGAP1 synaptic Ras GTPase activating protein 1
TACC2 transforming, acidic coiled-coil containing protein 2
TBC1D23 TBC1 domain family, member 23
TBC1D29 TBC1 domain family, member 29
TBPL2 TATA box binding protein like 2
TET3 tet methylcytosine dioxygenase 3
TGFBR1 transforming growth factor, beta receptor 1
THAP3 THAP domain containing, apoptosis associated protein 3
TKFC triokinase/FMN cyclase
TLN1 talin 1
TMPRSS13 transmembrane protease, serine 13
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOM1L1 target of myb1 (chicken)-like 1
TPCN1 two pore segment channel 1
TPR translocated promoter region, nuclear basket protein
TPSB2 tryptase beta 2 (gene/pseudogene)
TPTE transmembrane phosphatase with tensin homology
TRAPPC4 trafficking protein particle complex 4
TRIM32 tripartite motif containing 32
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TROAP trophinin associated protein
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSHZ3 teashirt zinc finger homeobox 3
TTN titin
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2O ubiquitin-conjugating enzyme E2O
UBE3B ubiquitin protein ligase E3B
UFC1 ubiquitin-fold modifier conjugating enzyme 1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UNC13C unc-13 homolog C (C. elegans)
USH1C Usher syndrome 1C (autosomal recessive, severe)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP1 ubiquitin specific peptidase 1
USP35 ubiquitin specific peptidase 35
USP42 ubiquitin specific peptidase 42
UTRN utrophin
VANGL2 VANGL planar cell polarity protein 2
VWA2 von Willebrand factor A domain containing 2
WDFY2 WD repeat and FYVE domain containing 2
WDR35 WD repeat domain 35
WDR61 WD repeat domain 61
WSCD2 WSC domain containing 2
YIPF2 Yip1 domain family, member 2
YLPM1 YLP motif containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZCCHC14 zinc finger, CCHC domain containing 14
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMYND8 zinc finger, MYND-type containing 8
ZNF253 zinc finger protein 253
ZNF257 zinc finger protein 257
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF385D zinc finger protein 385D
ZNF410 zinc finger protein 410
ZNF43 zinc finger protein 43
ZNF485 zinc finger protein 485
ZNF486 zinc finger protein 486
ZNF521 zinc finger protein 521
ZNF536 zinc finger protein 536
ZNF549 zinc finger protein 549
ZNF594 zinc finger protein 594
ZNF704 zinc finger protein 704
ZNF749 zinc finger protein 749
ZNF790 zinc finger protein 790
ZNF804A zinc finger protein 804A
ZNF805 zinc finger protein 805
ZNF816 zinc finger protein 816
ZNF845 zinc finger protein 845
ZNF91 zinc finger protein 91