LSM1 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description LSM1, U6 small nuclear RNA associated|This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 27257)
External Link http://www.ncbi.nlm.nih.gov/gene/27257
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Genes

84 interacting proteins for hub protein LSM1 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARF3 ADP-ribosylation factor 3
ATG12 autophagy related 12
ATG5 autophagy related 5
BCL6 B-cell CLL/lymphoma 6
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BECN1 beclin 1, autophagy related
CCDC101 coiled-coil domain containing 101
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CLIC1 chloride intracellular channel 1
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CST6 cystatin E/M
DCP2 decapping mRNA 2
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DUS2 dihydrouridine synthase 2
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
ECI1 enoyl-CoA delta isomerase 1
ELP3 elongator acetyltransferase complex subunit 3
ERCC1 excision repair cross-complementation group 1
EXOC8 exocyst complex component 8
EXOSC6 exosome component 6
EXOSC8 exosome component 8
FAM136A family with sequence similarity 136, member A
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FRS2 fibroblast growth factor receptor substrate 2
GLUD1 glutamate dehydrogenase 1
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTN3 histatin 3
ITC1 hypertrichosis universalis congenita, Ambras type
LSM1 LSM1, U6 small nuclear RNA associated
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MED10 mediator complex subunit 10
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MOB1A MOB kinase activator 1A
MSH3 mutS homolog 3
MSMO1 methylsterol monooxygenase 1
MSR1 macrophage scavenger receptor 1
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTM1 myotubularin 1
N4BP1 NEDD4 binding protein 1
NARS asparaginyl-tRNA synthetase
NCR1 natural cytotoxicity triggering receptor 1
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NQO1 NAD(P)H dehydrogenase, quinone 1
PRM3 protamine 3
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRC protein tyrosine phosphatase, receptor type, C
RFT1 RFT1 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SMN1 survival of motor neuron 1, telomeric
SOCS3 suppressor of cytokine signaling 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK3 serine/threonine kinase 3
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TMEM214 transmembrane protein 214
TOM1 target of myb1 (chicken)
TPCN1 two pore segment channel 1
TRAPPC2 trafficking protein particle complex 2
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
TUBGCP3 tubulin, gamma complex associated protein 3
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
UQCRH ubiquinol-cytochrome c reductase hinge protein
UXT ubiquitously-expressed, prefoldin-like chaperone
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR18 WD repeat domain 18