LSM4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)|This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 25804)
External Link http://www.ncbi.nlm.nih.gov/gene/25804
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361 interacting proteins for LSM4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A1CF APOBEC1 complementation factor
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACLY ATP citrate lyase
ADSL adenylosuccinate lyase
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP7 A kinase (PRKA) anchor protein 7
ALDOA aldolase A, fructose-bisphosphate
ALYREF Aly/REF export factor
AQR aquarius intron-binding spliceosomal factor
BCAS2 breast carcinoma amplified sequence 2
BCLAF1 BCL2-associated transcription factor 1
C14ORF166 chromosome 14 open reading frame 166
C19ORF53 chromosome 19 open reading frame 53
C3ORF17 chromosome 3 open reading frame 17
C9ORF78 chromosome 9 open reading frame 78
CALCOCO2 calcium binding and coiled-coil domain 2
CALML3 calmodulin-like 3
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPRIN1 cell cycle associated protein 1
CCAR1 cell division cycle and apoptosis regulator 1
CCDC12 coiled-coil domain containing 12
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC5L cell division cycle 5-like
CELF2 CUGBP, Elav-like family member 2
CIRBP cold inducible RNA binding protein
CKB creatine kinase, brain
CMSS1 cms1 ribosomal small subunit homolog (yeast)
COX5B cytochrome c oxidase subunit Vb
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRNKL1 crooked neck pre-mRNA splicing factor 1
CRYZ crystallin, zeta (quinone reductase)
CSDE1 cold shock domain containing E1, RNA-binding
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CWC15 CWC15 spliceosome-associated protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DARS aspartyl-tRNA synthetase
DAZAP1 DAZ associated protein 1
DBR1 debranching RNA lariats 1
DCP1A decapping mRNA 1A
DCP1B decapping mRNA 1B
DCP2 decapping mRNA 2
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
EAPP E2F-associated phosphoprotein
ECD ecdysoneless homolog (Drosophila)
EDC3 enhancer of mRNA decapping 3
EDC4 enhancer of mRNA decapping 4
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4H eukaryotic translation initiation factor 4H
ELAVL1 ELAV like RNA binding protein 1
EPRS glutamyl-prolyl-tRNA synthetase
ERH enhancer of rudimentary homolog (Drosophila)
ERI1 exoribonuclease 1
EWSR1 EWS RNA-binding protein 1
EXOSC4 exosome component 4
EXOSC6 exosome component 6
FABP4 fatty acid binding protein 4, adipocyte
FBL fibrillarin
FRG1 FSHD region gene 1
FUBP1 far upstream element (FUSE) binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GEMIN2 gem (nuclear organelle) associated protein 2
GEMIN5 gem (nuclear organelle) associated protein 5
GPHN gephyrin
GTF2B general transcription factor IIB
GTF2I general transcription factor IIi
HDLBP high density lipoprotein binding protein
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IARS isoleucyl-tRNA synthetase
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
KARS lysyl-tRNA synthetase
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM5B lysine (K)-specific demethylase 5B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT31 keratin 31, type I
KRT33B keratin 33B, type I
KRT34 keratin 34, type I
KRT81 keratin 81, type II
KRT85 keratin 85, type II
LARP1 La ribonucleoprotein domain family, member 1
LARP4B La ribonucleoprotein domain family, member 4B
LARS leucyl-tRNA synthetase
LDHA lactate dehydrogenase A
LGALS7B lectin, galactoside-binding, soluble, 7B
LIN28B lin-28 homolog B (C. elegans)
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC15 leucine rich repeat containing 15
LSM1 LSM1, U6 small nuclear RNA associated
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MATR3 matrin 3
MEPCE methylphosphate capping enzyme
MPO myeloperoxidase
MSH2 mutS homolog 2
MSI2 musashi RNA-binding protein 2
MTDH metadherin
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH4 myosin, heavy chain 4, skeletal muscle
N4BP2L2 NEDD4 binding protein 2-like 2
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCDN neurochondrin
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NME4 NME/NM23 nucleoside diphosphate kinase 4
NMI N-myc (and STAT) interactor
NONO non-POU domain containing, octamer-binding
NRF1 nuclear respiratory factor 1
NUCLEOLIN nucleolin multifunctional protein
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NXF1 nuclear RNA export factor 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PABPN1 poly(A) binding protein, nuclear 1
PARP1 poly (ADP-ribose) polymerase 1
PAXBP1 PAX3 and PAX7 binding protein 1
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PECR peroxisomal trans-2-enoyl-CoA reductase
PFDN1 prefoldin subunit 1
PFDN4 prefoldin subunit 4
PFDN5 prefoldin subunit 5
PFDN6 prefoldin subunit 6
PGAM2 phosphoglycerate mutase 2 (muscle)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLRG1 pleiotropic regulator 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT1 protein arginine methyltransferase 1
PRPF18 pre-mRNA processing factor 18
PRPF19 pre-mRNA processing factor 19
PRPF3 pre-mRNA processing factor 3
PRPF31 pre-mRNA processing factor 31
PRPF4 pre-mRNA processing factor 4
PRPF4B pre-mRNA processing factor 4B
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSPC1 paraspeckle component 1
PTBP1 polypyrimidine tract binding protein 1
PTBP3 polypyrimidine tract binding protein 3
PUF60 poly-U binding splicing factor 60KDa
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
QARS glutaminyl-tRNA synthetase
QKI QKI, KH domain containing, RNA binding
RAD23A RAD23 homolog A (S. cerevisiae)
RARS arginyl-tRNA synthetase
RASAL3 RAS protein activator like 3
RAVER1 ribonucleoprotein, PTB-binding 1
RBM14 RNA binding motif protein 14
RBM15 RNA binding motif protein 15
RBM22 RNA binding motif protein 22
RBM26 RNA binding motif protein 26
RBM27 RNA binding motif protein 27
RBM39 RNA binding motif protein 39
RBM42 RNA binding motif protein 42
RBMX RNA binding motif protein, X-linked
RECQL RecQ helicase-like
RHOXF2 Rhox homeobox family, member 2
RMI2 RecQ mediated genome instability 2
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNMT RNA (guanine-7-) methyltransferase
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPL17 ribosomal protein L17
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL26L1 ribosomal protein L26-like 1
RPL27A ribosomal protein L27a
RPL31 ribosomal protein L31
RPL35 ribosomal protein L35
RPL36A ribosomal protein L36a
RPL37 ribosomal protein L37
RPL38 ribosomal protein L38
RPL6 ribosomal protein L6
RPL8 ribosomal protein L8
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS28 ribosomal protein S28
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS9 ribosomal protein S9
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RSRC1 arginine/serine-rich coiled-coil 1
RTCA RNA 3'-terminal phosphate cyclase
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SART1 squamous cell carcinoma antigen recognized by T cells
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAF11 SR-related CTD-associated factor 11
SELENBP1 selenium binding protein 1
SERBP1 SERPINE1 mRNA binding protein 1
SF1 splicing factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFPQ splicing factor proline/glutamine-rich
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLIRP SRA stem-loop interacting RNA binding protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMIM14 small integral membrane protein 14
SMN2 survival of motor neuron 2, centromeric
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SND1 staphylococcal nuclease and tudor domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPG small nuclear ribonucleoprotein polypeptide G
SNRPN small nuclear ribonucleoprotein polypeptide N
SNW1 SNW domain containing 1
SRBD1 S1 RNA binding domain 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF11 serine/arginine-rich splicing factor 11
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STRAP serine/threonine kinase receptor associated protein
SUB1 SUB1 homolog (S. cerevisiae)
SYF2 SYF2 pre-mRNA-splicing factor
SYMPK symplekin
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARDBP TAR DNA binding protein
TCEA2 transcription elongation factor A (SII), 2
TFIP11 tuftelin interacting protein 11
THRAP3 thyroid hormone receptor associated protein 3
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TOE1 target of EGR1, member 1 (nuclear)
TOP1 topoisomerase (DNA) I
TRIM25 tripartite motif containing 25
TRMT6 tRNA methyltransferase 6
TRMT61A tRNA methyltransferase 61A
TSLIG2 tRNA splicing ligase complex subunit 2
TSLIG3A tRNA splicing ligase complex subunit 3A
TSLIG3B tRNA splicing ligase complex subunit 3B
TSSC4 tumor suppressing subtransferable candidate 4
TTC27 tetratricopeptide repeat domain 27
TUBB tubulin, beta class I
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXN thioredoxin
TXNL4A thioredoxin-like 4A
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBC ubiquitin C
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USP10 ubiquitin specific peptidase 10
USP15 ubiquitin specific peptidase 15
USP39 ubiquitin specific peptidase 39
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
VAC14 Vac14 homolog (S. cerevisiae)
VBP1 von Hippel-Lindau binding protein 1
VSIG8 V-set and immunoglobulin domain containing 8
WDR44 WD repeat domain 44
WWOX WW domain containing oxidoreductase
XAB2 XPA binding protein 2
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN1 5'-3' exoribonuclease 1
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNHIT2 zinc finger, HIT-type containing 2