LSM6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)|Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] (NCBI Entrez Gene Database, 11157)
External Link https://ncbi.nlm.nih.gov/gene/11157
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Genes

499 genes differentially expressed following the LSM6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 0.0127333
S100A9 S100 calcium binding protein A9 0.0107382
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0100437
CSTA cystatin A (stefin A) 0.00958784
KRT13 keratin 13, type I 0.0089419
ELANE elastase, neutrophil expressed 0.00885948
XPO7 exportin 7 0.00863787
ADIRF adipogenesis regulatory factor 0.00838794
TP63 tumor protein p63 0.00829961
ZDHHC6 zinc finger, DHHC-type containing 6 0.00822099
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00811978
SMNDC1 survival motor neuron domain containing 1 0.00783327
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00781869
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0077847
MNDA myeloid cell nuclear differentiation antigen 0.00777969
KRT15 keratin 15, type I 0.00775551
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00767775
SCGB1D2 secretoglobin, family 1D, member 2 0.0075352
CA12 carbonic anhydrase XII 0.00721307
TMEM87A transmembrane protein 87A 0.00718994
COL11A1 collagen, type XI, alpha 1 0.00705177
EREG epiregulin 0.00703557
NAV2 neuron navigator 2 0.00666962
TASOR2 transcription activation suppressor family member 2 0.00663447
S100A12 S100 calcium binding protein A12 0.00657418
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00655471
CRISP3 cysteine-rich secretory protein 3 0.00652186
PRPF3 pre-mRNA processing factor 3 0.00649381
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00649343
NOL11 nucleolar protein 11 0.00648228
CYBB cytochrome b-245, beta polypeptide 0.00644511
HBD hemoglobin, delta 0.00641399
CRABP2 cellular retinoic acid binding protein 2 0.00640247
AKAP8 A kinase (PRKA) anchor protein 8 0.0063558
ANXA3 annexin A3 0.00630924
YME1L1 YME1-like 1 ATPase 0.00629925
CD9 CD9 molecule 0.00627018
S100A6 S100 calcium binding protein A6 0.00622289
CXCL9 chemokine (C-X-C motif) ligand 9 0.00614283
HILPDA hypoxia inducible lipid droplet-associated 0.00613701
SCPEP1 serine carboxypeptidase 1 0.00605534
PRPF18 pre-mRNA processing factor 18 0.0060276
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0060071
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.00598952
JMJD6 jumonji domain containing 6 0.00591891
NUP58 nucleoporin 58 0.0059002
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00588694
MGAM maltase-glucoamylase 0.00582908
AFF1 AF4/FMR2 family, member 1 0.00582378
HK2 hexokinase 2 0.00582367
GBP2 guanylate binding protein 2, interferon-inducible 0.00581507
ZBED2 zinc finger, BED-type containing 2 0.00580905
KRT6A keratin 6A, type II 0.00579908
PRPF4 pre-mRNA processing factor 4 0.00579906
MT1X metallothionein 1X 0.00576177
KRT7 keratin 7, type II 0.0057492
ADM adrenomedullin 0.00568122
MXI1 MAX interactor 1, dimerization protein 0.00568079
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00566558
TNS3 tensin 3 0.00562733
EIF6 eukaryotic translation initiation factor 6 0.00559056
DDIT3 DNA-damage-inducible transcript 3 0.0055629
CORO1C coronin, actin binding protein, 1C 0.00553638
TPD52 tumor protein D52 0.00549085
LSG1 large 60S subunit nuclear export GTPase 1 0.00547502
MME membrane metallo-endopeptidase 0.00545857
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.00545451
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 0.00544016
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.00543657
TMPRSS11E transmembrane protease, serine 11E 0.00540142
MPO myeloperoxidase 0.00539443
KRT81 keratin 81, type II 0.00538963
TP53 tumor protein p53 0.00538002
HSPA14 heat shock 70kDa protein 14 0.00535201
GPNMB glycoprotein (transmembrane) nmb 0.00530263
GLDC glycine dehydrogenase (decarboxylating) 0.0052868
ALOX5 arachidonate 5-lipoxygenase 0.00528514
API5 apoptosis inhibitor 5 0.00528326
KDM3A lysine (K)-specific demethylase 3A 0.0052728
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.00523324
MRPS30 mitochondrial ribosomal protein S30 0.00519741
RSRC2 arginine/serine-rich coiled-coil 2 0.00519546
SPRR3 small proline-rich protein 3 0.005183
ANGPTL2 angiopoietin-like 2 0.00511848
GAB2 GRB2-associated binding protein 2 0.00510713
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.00503542
GTPBP4 GTP binding protein 4 0.00502682
RNF6 ring finger protein (C3H2C3 type) 6 0.00501837
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00501323
WDR43 WD repeat domain 43 0.00500326
AZU1 azurocidin 1 0.00498004
MMP8 matrix metallopeptidase 8 0.00496958
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00496151
PUM3 pumilio RNA binding family member 3 0.00496077
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00496045
CAV2 caveolin 2 0.00493257
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.00492959
LTBP2 latent transforming growth factor beta binding protein 2 0.00492826
CTSB cathepsin B 0.00492476
TPD52L1 tumor protein D52-like 1 0.00492289
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.00491207
ASCC3 activating signal cointegrator 1 complex subunit 3 0.00491002
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00489321
CXCL11 chemokine (C-X-C motif) ligand 11 0.00487919
ZNHIT6 zinc finger, HIT-type containing 6 0.00487413
GBP1 guanylate binding protein 1, interferon-inducible 0.00487053
LSP1 lymphocyte-specific protein 1 0.00485377
MMP12 matrix metallopeptidase 12 0.00484062
NAT10 N-acetyltransferase 10 (GCN5-related) 0.00483472
FZD6 frizzled class receptor 6 0.0048275
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00481452
PKM pyruvate kinase, muscle 0.00481416
CHD7 chromodomain helicase DNA binding protein 7 0.00480086
TACSTD2 tumor-associated calcium signal transducer 2 0.00479992
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00479257
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00478727
EIF5B eukaryotic translation initiation factor 5B 0.00478667
ZNF750 zinc finger protein 750 0.00478471
RAB14 RAB14, member RAS oncogene family 0.0047838
VWA8 von Willebrand factor A domain containing 8 0.00478142
ACTB actin, beta 0.00477205
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00477085
ETV1 ets variant 1 0.00476688
C1QB complement component 1, q subcomponent, B chain 0.00476174
BCL2A1 BCL2-related protein A1 0.00474709
FABP4 fatty acid binding protein 4, adipocyte 0.00474566
SC5D sterol-C5-desaturase 0.00474288
SUSD6 sushi domain containing 6 0.00473246
DEFA4 defensin, alpha 4, corticostatin 0.00472624
IFI16 interferon, gamma-inducible protein 16 0.00472459
ASCL1 achaete-scute family bHLH transcription factor 1 0.00471738
USPL1 ubiquitin specific peptidase like 1 0.00470811
PUF60 poly-U binding splicing factor 60KDa 0.00469819
RNASE3 ribonuclease, RNase A family, 3 0.00468817
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.004641
BCHE butyrylcholinesterase 0.00464037
STK17B serine/threonine kinase 17b 0.00463889
FNDC3B fibronectin type III domain containing 3B 0.00462687
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00462668
AIM2 absent in melanoma 2 0.00462319
ZNF451 zinc finger protein 451 0.00462005
TGFBR3 transforming growth factor, beta receptor III 0.0046167
ADAM9 ADAM metallopeptidase domain 9 0.00460606
NOL8 nucleolar protein 8 0.00460243
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0045906
KLHL9 kelch-like family member 9 0.00458047
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00457404
PGAP3 post-GPI attachment to proteins 3 0.00456806
MTPAP mitochondrial poly(A) polymerase 0.00452609
RND3 Rho family GTPase 3 0.00451956
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00450858
GPR87 G protein-coupled receptor 87 0.0045031
ING3 inhibitor of growth family, member 3 0.00449488
CXCL10 chemokine (C-X-C motif) ligand 10 0.00449257
SFRP4 secreted frizzled-related protein 4 0.0044696
ADAM10 ADAM metallopeptidase domain 10 0.00445687
MET MET proto-oncogene, receptor tyrosine kinase 0.00445419
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.00444612
PRTN3 proteinase 3 0.00444397
ICE1 interactor of little elongation complex ELL subunit 1 0.00444019
ZNF148 zinc finger protein 148 0.00442015
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.0044184
CD163 CD163 molecule 0.00440227
USP3 ubiquitin specific peptidase 3 0.00438572
SPRR1B small proline-rich protein 1B 0.00438342
ADNP activity-dependent neuroprotector homeobox 0.00437611
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00437609
PMM2 phosphomannomutase 2 0.00436787
VSIG4 V-set and immunoglobulin domain containing 4 0.00436645
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00436606
RWDD1 RWD domain containing 1 0.00436191
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00435723
COPB1 coatomer protein complex, subunit beta 1 0.00435553
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00433054
CREBZF CREB/ATF bZIP transcription factor 0.00431238
DSE dermatan sulfate epimerase 0.00429877
CTSC cathepsin C 0.00429771
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.00429603
BTN2A1 butyrophilin, subfamily 2, member A1 0.00428768
RFC3 replication factor C (activator 1) 3, 38kDa 0.00428439
BMP7 bone morphogenetic protein 7 0.00428057
CEPT1 choline/ethanolamine phosphotransferase 1 0.00427813
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00427063
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00427063
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00426893
BPGM 2,3-bisphosphoglycerate mutase 0.00426508
ACTN4 actinin, alpha 4 0.00424807
CTSS cathepsin S 0.00424765
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) 0.00423646
S100A11 S100 calcium binding protein A11 0.0042347
GABPB1 GA binding protein transcription factor, beta subunit 1 0.0042342
MAK16 MAK16 homolog (S. cerevisiae) 0.00423195
MT1E metallothionein 1E 0.00423155
TGDS TDP-glucose 4,6-dehydratase 0.00422587
LY6D lymphocyte antigen 6 complex, locus D 0.00422549
MYLIP myosin regulatory light chain interacting protein 0.0042233
CUL2 cullin 2 0.00421937
LRP2 low density lipoprotein receptor-related protein 2 0.00421228
ZNF430 zinc finger protein 430 0.00420879
RIT1 Ras-like without CAAX 1 0.00420477
ELP1 elongator acetyltransferase complex subunit 1 0.00419999
WAC WW domain containing adaptor with coiled-coil 0.00419835
KIN Kin17 DNA and RNA binding protein 0.00419629
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00417544
SCGB2A2 secretoglobin, family 2A, member 2 0.00417119
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00416931
U2SURP U2 snRNP-associated SURP domain containing 0.00416514
CTSG cathepsin G 0.00415766
KRT5 keratin 5, type II 0.00415275
RHOT1 ras homolog family member T1 0.00415199
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.00414532
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.00414428
LRRC8D leucine rich repeat containing 8 family, member D 0.00413902
RPIA ribose 5-phosphate isomerase A 0.00413636
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.00413476
MMP9 matrix metallopeptidase 9 0.00413251
GLUL glutamate-ammonia ligase 0.00411721
BBX bobby sox homolog (Drosophila) 0.00410869
FRMD4B FERM domain containing 4B 0.0041069
PUM2 pumilio RNA-binding family member 2 0.00410529
MED6 mediator complex subunit 6 0.00410128
PANX1 pannexin 1 0.00407888
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00407753
TMEM9B TMEM9 domain family, member B 0.00407077
KDM5D lysine (K)-specific demethylase 5D 0.00406898
TFB2M transcription factor B2, mitochondrial 0.00406431
SEPP1 selenoprotein P, plasma, 1 0.00406156
KTN1 kinectin 1 (kinesin receptor) 0.00405973
PDHX pyruvate dehydrogenase complex, component X 0.00405969
ZMPSTE24 zinc metallopeptidase STE24 0.0040571
TCF12 transcription factor 12 0.00405004
IARS1 isoleucyl-tRNA synthetase 1 0.00404884
CREG1 cellular repressor of E1A-stimulated genes 1 0.00403886
NFASC neurofascin 0.00401202
GSTO1 glutathione S-transferase omega 1 0.00400906
SCEL sciellin 0.00398697
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 0.00398594
SEPTIN7 septin 7 0.00398105
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00397969
CRYBG1 crystallin beta-gamma domain containing 1 0.00397739
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.00397546
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.00397407
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00396497
SMIM7 small integral membrane protein 7 0.00396492
IGFBP6 insulin-like growth factor binding protein 6 0.00395855
PCGF1 polycomb group ring finger 1 0.00395751
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.00395427
DSG3 desmoglein 3 0.00395422
CLDND1 claudin domain containing 1 0.00394922
NDC1 NDC1 transmembrane nucleoporin 0.00394887

decreased expression

Symbol Name Standardized Value
ISG15 ISG15 ubiquitin-like modifier -0.0120135
PLK2 polo-like kinase 2 -0.0100492
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00945412
MDK midkine (neurite growth-promoting factor 2) -0.00923095
TUBB2A tubulin, beta 2A class IIa -0.00889289
MARCKSL1 MARCKS-like 1 -0.00887073
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00871519
PDLIM3 PDZ and LIM domain 3 -0.00862016
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00854497
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00842416
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00839153
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00832244
KIF20A kinesin family member 20A -0.00831665
THBS1 thrombospondin 1 -0.00828539
CDC45 cell division cycle 45 -0.00818837
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00809539
CHKB choline kinase beta -0.00798591
TSPAN8 tetraspanin 8 -0.00787721
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00785154
DMAC2L distal membrane arm assembly component 2 like -0.00780703
DYNLL1 dynein, light chain, LC8-type 1 -0.00763977
GPX4 glutathione peroxidase 4 -0.00760485
TMSB15A thymosin beta 15a -0.00760451
SORBS1 sorbin and SH3 domain containing 1 -0.00740955
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00740125
DLK1 delta-like 1 homolog (Drosophila) -0.00722116
MMD monocyte to macrophage differentiation-associated -0.00718478
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00708315
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00688774
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00685188
ACOT9 acyl-CoA thioesterase 9 -0.0068124
TGFBI transforming growth factor, beta-induced, 68kDa -0.00680626
SST somatostatin -0.00680134
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00674318
AGR2 anterior gradient 2 -0.00674274
NUSAP1 nucleolar and spindle associated protein 1 -0.00673364
TUBA1A tubulin, alpha 1a -0.00670899
WSB2 WD repeat and SOCS box containing 2 -0.00663558
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00653825
TCTA T-cell leukemia translocation altered -0.00646819
ACADVL acyl-CoA dehydrogenase, very long chain -0.00646466
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.00645138
ATF3 activating transcription factor 3 -0.00644701
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00642272
IFI35 interferon-induced protein 35 -0.00640408
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00638602
CD36 CD36 molecule (thrombospondin receptor) -0.006377
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.00623417
RHOB ras homolog family member B -0.00620433
SMC1A structural maintenance of chromosomes 1A -0.00618338
HSPA1A heat shock 70kDa protein 1A -0.00612899
IER5 immediate early response 5 -0.0061284
FGF13 fibroblast growth factor 13 -0.00608696
IFI27 interferon, alpha-inducible protein 27 -0.00600442
KLHDC2 kelch domain containing 2 -0.00598327
REG1A regenerating islet-derived 1 alpha -0.00594814
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00593859
ACAA2 acetyl-CoA acyltransferase 2 -0.00589738
MX1 MX dynamin-like GTPase 1 -0.00585507
REEP1 receptor accessory protein 1 -0.00583896
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00583767
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00582246
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00580983
NELL2 NEL-like 2 (chicken) -0.00580034
CLGN calmegin -0.00579408
TFF1 trefoil factor 1 -0.00577524
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0057486
SORBS2 sorbin and SH3 domain containing 2 -0.00572314
ASS1 argininosuccinate synthase 1 -0.00571366
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00570455
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00570051
NID1 nidogen 1 -0.00569497
SIDT2 SID1 transmembrane family, member 2 -0.00567627
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00566062
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00565792
CLCA1 chloride channel accessory 1 -0.00565072
PROM1 prominin 1 -0.00563019
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00562574
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00561389
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00559799
KLK1 kallikrein 1 -0.00559025
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00558838
MLF1 myeloid leukemia factor 1 -0.00557803
TSPAN1 tetraspanin 1 -0.00556906
RELN reelin -0.00556064
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00554898
PNMA1 paraneoplastic Ma antigen 1 -0.00554776
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0055347
HP haptoglobin -0.00552683
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0055172
SEPTIN6 septin 6 -0.00550812
DPYSL2 dihydropyrimidinase-like 2 -0.00548865
DES desmin -0.00548652
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00547515
LEF1 lymphoid enhancer-binding factor 1 -0.00546609
EDNRB endothelin receptor type B -0.0054602
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00544782
IFI44L interferon-induced protein 44-like -0.00543569
KCTD12 potassium channel tetramerization domain containing 12 -0.0054337
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00540289
SMTN smoothelin -0.00539481
COCH cochlin -0.00539479
HMG20B high mobility group 20B -0.0053823
XIC X chromosome inactivation center -0.00533209
FKBP11 FK506 binding protein 11, 19 kDa -0.00533198
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00531675
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00531135
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00528039
ZBED1 zinc finger, BED-type containing 1 -0.00527333
DMD dystrophin -0.00526207
TSPAN13 tetraspanin 13 -0.00524194
FNBP1 formin binding protein 1 -0.0052286
HSPB11 heat shock protein family B (small), member 11 -0.00522413
TRMT5 tRNA methyltransferase 5 -0.00521986
CEP68 centrosomal protein 68kDa -0.00520435
SLC44A4 solute carrier family 44, member 4 -0.00519826
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00519629
CP ceruloplasmin (ferroxidase) -0.00518671
DUSP22 dual specificity phosphatase 22 -0.00516265
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0051444
RNASEH2A ribonuclease H2, subunit A -0.00513283
NPY neuropeptide Y -0.00512355
FANCA Fanconi anemia, complementation group A -0.00512103
ANPEP alanyl (membrane) aminopeptidase -0.00511242
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00509487
TFPI2 tissue factor pathway inhibitor 2 -0.00509268
FHL1 four and a half LIM domains 1 -0.00508857
RGS10 regulator of G-protein signaling 10 -0.00507844
IFI6 interferon, alpha-inducible protein 6 -0.00507502
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00507193
TJP3 tight junction protein 3 -0.00503762
TUBB3 tubulin, beta 3 class III -0.00502059
OPHN1 oligophrenin 1 -0.00501502
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00499998
MGLL monoglyceride lipase -0.00498
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.00497976
IFITM1 interferon induced transmembrane protein 1 -0.00496794
NTAN1 N-terminal asparagine amidase -0.00496519
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00495984
NPEPL1 aminopeptidase-like 1 -0.00494929
NRIP1 nuclear receptor interacting protein 1 -0.00494661
TRAPPC3 trafficking protein particle complex 3 -0.00490072
WASHC3 WASH complex subunit 3 -0.00488887
CD302 CD302 molecule -0.00487215
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00486531
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00485017
C4BPB complement component 4 binding protein, beta -0.00483571
LAMA2 laminin, alpha 2 -0.00481752
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00479553
PEG3 paternally expressed 3 -0.00479149
GMDS GDP-mannose 4,6-dehydratase -0.00479077
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.00478204
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0047792
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.00474221
CENPU centromere protein U -0.00474207
APOLD1 apolipoprotein L domain containing 1 -0.00473551
ACTA1 actin, alpha 1, skeletal muscle -0.00473268
TMPRSS2 transmembrane protease, serine 2 -0.00471087
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00470951
RGS2 regulator of G-protein signaling 2 -0.00470516
TPGS2 tubulin polyglutamylase complex subunit 2 -0.00470044
DALRD3 DALR anticodon binding domain containing 3 -0.00469169
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00469013
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00469012
A2M alpha-2-macroglobulin -0.00468127
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00467739
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00467345
CHKA choline kinase alpha -0.00466563
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00465269
TNNT1 troponin T type 1 (skeletal, slow) -0.00464999
DMBT1 deleted in malignant brain tumors 1 -0.00464647
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00464635
IFITM3 interferon induced transmembrane protein 3 -0.00464264
LYPD1 LY6/PLAUR domain containing 1 -0.00464152
SPATA20 spermatogenesis associated 20 -0.00463518
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00462487
ECI2 enoyl-CoA delta isomerase 2 -0.00462387
C3 complement component 3 -0.00462143
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00461357
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00460867
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00459087
LONP2 lon peptidase 2, peroxisomal -0.00458442
F2R coagulation factor II (thrombin) receptor -0.004584
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.00456858
DPH5 diphthamide biosynthesis 5 -0.00456387
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00456073
LETMD1 LETM1 domain containing 1 -0.00455757
KLF2 Kruppel-like factor 2 -0.00455482
OXA1L oxidase (cytochrome c) assembly 1-like -0.00453791
GCHFR GTP cyclohydrolase I feedback regulator -0.00451045
RTN1 reticulon 1 -0.00450905
PDGFC platelet derived growth factor C -0.00450438
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0045009
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.00450004
NAAA N-acylethanolamine acid amidase -0.00448812
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00448389
GATA2 GATA binding protein 2 -0.00447771
ABHD3 abhydrolase domain containing 3 -0.00445551
TST thiosulfate sulfurtransferase (rhodanese) -0.00445472
CPE carboxypeptidase E -0.00445109
HMGN2 high mobility group nucleosomal binding domain 2 -0.00444445
PLK1 polo-like kinase 1 -0.00444234
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.00443427
RFK riboflavin kinase -0.00442765
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00442092
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00439976
AMDHD2 amidohydrolase domain containing 2 -0.00439518
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00439472
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.00439018
PHYH phytanoyl-CoA 2-hydroxylase -0.00438978
CFB complement factor B -0.00438743
RHOBTB3 Rho-related BTB domain containing 3 -0.00438715
C8ORF4 chromosome 8 open reading frame 4 -0.00438644
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00438043
TCF15 transcription factor 15 (basic helix-loop-helix) -0.00437706
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.00437186
ADRA2A adrenoceptor alpha 2A -0.00436866
HMGA1 high mobility group AT-hook 1 -0.00436653
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00436242
USP18 ubiquitin specific peptidase 18 -0.00436037
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00435727
MRPS16 mitochondrial ribosomal protein S16 -0.00435577
IL17RB interleukin 17 receptor B -0.00434336
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00434
GADD45B growth arrest and DNA-damage-inducible, beta -0.00433724
WDR45 WD repeat domain 45 -0.00433279
COQ8A coenzyme Q8A -0.00433161
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -0.00432106
NPY1R neuropeptide Y receptor Y1 -0.00432026
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00431768
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00430914
TEAD4 TEA domain family member 4 -0.00430587
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00430387
C11ORF71 chromosome 11 open reading frame 71 -0.00429394
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0042897
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00428564
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00428419
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00427869
INHBB inhibin, beta B -0.00427747
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00426868
IFI44 interferon-induced protein 44 -0.00426828
GAL galanin/GMAP prepropeptide -0.00426024
CADPS2 Ca++-dependent secretion activator 2 -0.00424962
CIT citron rho-interacting serine/threonine kinase -0.00424162
CD83 CD83 molecule -0.00422881
PASK PAS domain containing serine/threonine kinase -0.00422805
ZG16 zymogen granule protein 16 -0.00422165
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00422022
YPEL1 yippee-like 1 (Drosophila) -0.00421413