LSM7 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)|Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] (NCBI Entrez Gene Database, 51690)
External Link https://ncbi.nlm.nih.gov/gene/51690
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Genes

498 genes differentially expressed following the LSM7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MME membrane metallo-endopeptidase 0.0134779
FABP4 fatty acid binding protein 4, adipocyte 0.0129099
XPO7 exportin 7 0.0120806
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0119604
CRABP2 cellular retinoic acid binding protein 2 0.0119506
SSBP2 single-stranded DNA binding protein 2 0.011416
MXI1 MAX interactor 1, dimerization protein 0.010803
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0104878
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0101152
TPD52 tumor protein D52 0.00995718
CXCR4 chemokine (C-X-C motif) receptor 4 0.00987026
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00941137
JMJD6 jumonji domain containing 6 0.00928251
SEPP1 selenoprotein P, plasma, 1 0.00924828
RGS5 regulator of G-protein signaling 5 0.00917553
BHLHE41 basic helix-loop-helix family, member e41 0.00904527
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00895035
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00884215
GBP2 guanylate binding protein 2, interferon-inducible 0.00879585
HILPDA hypoxia inducible lipid droplet-associated 0.00873283
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00869586
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00867685
SCGB2A2 secretoglobin, family 2A, member 2 0.00853257
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00845038
RAB20 RAB20, member RAS oncogene family 0.00818522
ADIRF adipogenesis regulatory factor 0.0080863
SGCE sarcoglycan, epsilon 0.0080339
UBE2H ubiquitin-conjugating enzyme E2H 0.00778919
ADM adrenomedullin 0.00765652
PDGFD platelet derived growth factor D 0.00762672
CAV2 caveolin 2 0.00761801
SFRP4 secreted frizzled-related protein 4 0.00756621
VWA8 von Willebrand factor A domain containing 8 0.00750016
TGFBR3 transforming growth factor, beta receptor III 0.00748188
SCGB1D2 secretoglobin, family 1D, member 2 0.00742161
RHOH ras homolog family member H 0.00738009
STOM stomatin 0.00737171
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.00733869
CTTN cortactin 0.00733689
PRPF3 pre-mRNA processing factor 3 0.00731224
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00729706
GAB2 GRB2-associated binding protein 2 0.00729571
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00724565
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00721534
HK2 hexokinase 2 0.00716537
RGCC regulator of cell cycle 0.00713863
ABHD4 abhydrolase domain containing 4 0.00712988
COL11A1 collagen, type XI, alpha 1 0.0071254
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00710856
MNDA myeloid cell nuclear differentiation antigen 0.00708411
SMNDC1 survival motor neuron domain containing 1 0.00707617
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00705903
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00705866
GLUL glutamate-ammonia ligase 0.00703625
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.00701387
FGFR1 fibroblast growth factor receptor 1 0.00699266
AKAP8 A kinase (PRKA) anchor protein 8 0.00691501
PRPF4 pre-mRNA processing factor 4 0.00686149
ZHX2 zinc fingers and homeoboxes 2 0.00685398
ANXA3 annexin A3 0.00685333
PDGFRL platelet-derived growth factor receptor-like 0.00682068
AIM2 absent in melanoma 2 0.00681117
AUTS2 autism susceptibility candidate 2 0.00677342
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00677243
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.00674236
CRYAB crystallin, alpha B 0.00674186
IGFBP6 insulin-like growth factor binding protein 6 0.00673867
JAM3 junctional adhesion molecule 3 0.00671013
OLFML2A olfactomedin-like 2A 0.00670254
RSL1D1 ribosomal L1 domain containing 1 0.0066993
ENSA endosulfine alpha 0.00669546
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00664482
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.00664322
ACTB actin, beta 0.00662846
CSTA cystatin A (stefin A) 0.0066167
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0066023
TMEM100 transmembrane protein 100 0.00660001
PDE4B phosphodiesterase 4B, cAMP-specific 0.00656468
WLS wntless Wnt ligand secretion mediator 0.00654548
IFI16 interferon, gamma-inducible protein 16 0.00653196
C8ORF33 chromosome 8 open reading frame 33 0.006529
PRDX1 peroxiredoxin 1 0.00650338
PRKD2 protein kinase D2 0.00648978
OXTR oxytocin receptor 0.00646771
CHD7 chromodomain helicase DNA binding protein 7 0.00645605
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00645328
TNS3 tensin 3 0.00644977
SELE selectin E 0.00639253
IGF1R insulin-like growth factor 1 receptor 0.00636034
HHEX hematopoietically expressed homeobox 0.00635674
KLK10 kallikrein-related peptidase 10 0.00633374
MED6 mediator complex subunit 6 0.00632815
ADGRL2 adhesion G protein-coupled receptor L2 0.00632115
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.00631934
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00628605
MSMO1 methylsterol monooxygenase 1 0.00628333
GPX2 glutathione peroxidase 2 0.00624446
TPM4 tropomyosin 4 0.00623849
IL1RN interleukin 1 receptor antagonist 0.00623179
BHMT2 betaine--homocysteine S-methyltransferase 2 0.00619841
IL15 interleukin 15 0.00617787
TNS1 tensin 1 0.00617344
DDR2 discoidin domain receptor tyrosine kinase 2 0.00617067
PBX1 pre-B-cell leukemia homeobox 1 0.00614584
TP63 tumor protein p63 0.00613681
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.0061296
AKAP12 A kinase (PRKA) anchor protein 12 0.0060922
IFNGR1 interferon gamma receptor 1 0.00609117
MCL1 myeloid cell leukemia 1 0.00608854
CLIC5 chloride intracellular channel 5 0.00608757
MYL9 myosin, light chain 9, regulatory 0.00608412
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00608159
HMOX1 heme oxygenase 1 0.00607665
DCTN6 dynactin 6 0.00601748
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0060165
EFHD1 EF-hand domain family, member D1 0.00601266
ISG20 interferon stimulated exonuclease gene 20kDa 0.00598881
PTHLH parathyroid hormone-like hormone 0.00598519
RPIA ribose 5-phosphate isomerase A 0.00596136
TMEM33 transmembrane protein 33 0.0059457
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00592567
AFF1 AF4/FMR2 family, member 1 0.00591418
CAV1 caveolin 1, caveolae protein, 22kDa 0.0058817
ZDHHC6 zinc finger, DHHC-type containing 6 0.00586399
CLU clusterin 0.00584047
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00583577
AUH AU RNA binding protein/enoyl-CoA hydratase 0.00581789
CTSK cathepsin K 0.00581686
GAS1 growth arrest-specific 1 0.00581218
FOXO1 forkhead box O1 0.00578254
GABPB1 GA binding protein transcription factor, beta subunit 1 0.00577383
DPYSL3 dihydropyrimidinase-like 3 0.00575998
GOLM1 golgi membrane protein 1 0.00575361
MCAM melanoma cell adhesion molecule 0.00574413
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00573106
ABLIM1 actin binding LIM protein 1 0.00572585
DIO2 deiodinase, iodothyronine, type II 0.00571008
CYB5A cytochrome b5 type A (microsomal) 0.00570963
FTO fat mass and obesity associated 0.00570804
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00570775
PALLD palladin, cytoskeletal associated protein 0.00568511
RNMT RNA (guanine-7-) methyltransferase 0.00567419
PAM peptidylglycine alpha-amidating monooxygenase 0.00566742
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00565788
CFDP1 craniofacial development protein 1 0.00561807
CFI complement factor I 0.00561634
LTBP2 latent transforming growth factor beta binding protein 2 0.00561039
CD99 CD99 molecule 0.00560326
FGF1 fibroblast growth factor 1 (acidic) 0.00559141
NRCAM neuronal cell adhesion molecule 0.00553241
RBM47 RNA binding motif protein 47 0.00552353
PELI1 pellino E3 ubiquitin protein ligase 1 0.00552103
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00552007
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00550417
NT5C2 5'-nucleotidase, cytosolic II 0.00549645
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00549431
DMTF1 cyclin D binding myb-like transcription factor 1 0.00549101
ELL2 elongation factor, RNA polymerase II, 2 0.00548405
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00547264
POPDC3 popeye domain containing 3 0.00547049
IARS1 isoleucyl-tRNA synthetase 1 0.00546995
CA2 carbonic anhydrase II 0.00546578
BMPR1A bone morphogenetic protein receptor, type IA 0.00546472
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00546396
GSTP1 glutathione S-transferase pi 1 0.00544432
MRPS28 mitochondrial ribosomal protein S28 0.00544424
KLK13 kallikrein-related peptidase 13 0.0054416
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00544146
BCAP31 B-cell receptor-associated protein 31 0.00543717
TMEM255A transmembrane protein 255A 0.00541436
HSPA4 heat shock 70kDa protein 4 0.00539796
STIP1 stress-induced phosphoprotein 1 0.00539575
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00539402
RPP38 ribonuclease P/MRP 38kDa subunit 0.0053689
MMP9 matrix metallopeptidase 9 0.00535564
HEATR1 HEAT repeat containing 1 0.00535243
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00533668
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00533222
FZD6 frizzled class receptor 6 0.00532319
ZNF451 zinc finger protein 451 0.00532157
PTCH1 patched 1 0.00531225
MMP3 matrix metallopeptidase 3 0.00531187
EXT1 exostosin glycosyltransferase 1 0.00531067
BFAR bifunctional apoptosis regulator 0.00530762
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00529823
ZNF394 zinc finger protein 394 0.00527521
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0052733
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00525885
KIAA0040 KIAA0040 0.00525047
UCK2 uridine-cytidine kinase 2 0.00524257
RIOK2 RIO kinase 2 0.00524245
UIMC1 ubiquitin interaction motif containing 1 0.0052153
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.00520986
ACVR1B activin A receptor, type IB 0.00520616
PLAG1 pleiomorphic adenoma gene 1 0.00520408
FMO1 flavin containing monooxygenase 1 0.00519895
ZNF430 zinc finger protein 430 0.00519227
LAMA4 laminin, alpha 4 0.00517873
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.00517373
GPC3 glypican 3 0.00517286
ICE1 interactor of little elongation complex ELL subunit 1 0.00516554
ADAM12 ADAM metallopeptidase domain 12 0.0051596
VLDLR very low density lipoprotein receptor 0.00515237
CUL4A cullin 4A 0.00513475
MANF mesencephalic astrocyte-derived neurotrophic factor 0.00512755
ACSL3 acyl-CoA synthetase long-chain family member 3 0.00511422
STK17B serine/threonine kinase 17b 0.0050941
AQP1 aquaporin 1 (Colton blood group) 0.0050878
C10ORF10 chromosome 10 open reading frame 10 0.00508646
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.00508597
TMPRSS11E transmembrane protease, serine 11E 0.00507712
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.0050745
NES nestin 0.00505708
INTS9 integrator complex subunit 9 0.00504878
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00504672
MTPAP mitochondrial poly(A) polymerase 0.00504237
PDHX pyruvate dehydrogenase complex, component X 0.00503862
PTN pleiotrophin 0.0050363
BCL6 B-cell CLL/lymphoma 6 0.00503608
WAC WW domain containing adaptor with coiled-coil 0.00503586
TENT5A terminal nucleotidyltransferase 5A 0.00503022
BPGM 2,3-bisphosphoglycerate mutase 0.00502019
BTN2A1 butyrophilin, subfamily 2, member A1 0.00501217
USPL1 ubiquitin specific peptidase like 1 0.00501059
NOL11 nucleolar protein 11 0.00500795
NOTCH3 notch 3 0.00500327
PER2 period circadian clock 2 0.00499926
NAT10 N-acetyltransferase 10 (GCN5-related) 0.00499254
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00498757
RIOX2 ribosomal oxygenase 2 0.00498281
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00497914
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00497756
TMEM243 transmembrane protein 243, mitochondrial 0.00497096
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.00496325
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00495919
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00494634
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00494044
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00492992
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 0.00492655
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00491338
AKAP17A A kinase (PRKA) anchor protein 17A 0.00490968
KRT13 keratin 13, type I 0.00490813
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.00490629
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00490217
OSBPL2 oxysterol binding protein-like 2 0.00489593
MELK maternal embryonic leucine zipper kinase 0.00488824
IL32 interleukin 32 0.00488752
OLFML1 olfactomedin-like 1 0.00488618
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.0048821
WDR43 WD repeat domain 43 0.00487733

decreased expression

Symbol Name Standardized Value
PLK2 polo-like kinase 2 -0.0139339
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0115579
TUBA1A tubulin, alpha 1a -0.0108069
WSB2 WD repeat and SOCS box containing 2 -0.0106512
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0101803
TFPI2 tissue factor pathway inhibitor 2 -0.00999482
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.0099399
ANXA4 annexin A4 -0.00990928
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00980082
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00965685
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00961419
SPATA20 spermatogenesis associated 20 -0.00955236
NPTX2 neuronal pentraxin II -0.00953645
ACOT9 acyl-CoA thioesterase 9 -0.00949185
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00934257
TPSAB1 tryptase alpha/beta 1 -0.00907008
IGFBP1 insulin-like growth factor binding protein 1 -0.00888893
DMAC2L distal membrane arm assembly component 2 like -0.00888391
NPY neuropeptide Y -0.00883028
COCH cochlin -0.00859783
CENPU centromere protein U -0.00853443
IFI6 interferon, alpha-inducible protein 6 -0.00828677
REG1A regenerating islet-derived 1 alpha -0.00824801
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -0.00807793
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00807476
TST thiosulfate sulfurtransferase (rhodanese) -0.00797535
PROM1 prominin 1 -0.00794454
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00792163
CLGN calmegin -0.00782751
PRUNE2 prune homolog 2 (Drosophila) -0.00781031
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00767365
AGR2 anterior gradient 2 -0.00760569
NPTX1 neuronal pentraxin I -0.00755832
THBS1 thrombospondin 1 -0.00749082
CDC45 cell division cycle 45 -0.00748917
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00742971
SFN stratifin -0.00739357
TPM1 tropomyosin 1 (alpha) -0.00736782
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00734401
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00733249
PCP4 Purkinje cell protein 4 -0.00722419
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00718628
CDCP1 CUB domain containing protein 1 -0.0071367
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00712221
TGFBI transforming growth factor, beta-induced, 68kDa -0.00709796
KIF20A kinesin family member 20A -0.00709739
MLF1 myeloid leukemia factor 1 -0.00707502
PRAME preferentially expressed antigen in melanoma -0.00706622
GPX4 glutathione peroxidase 4 -0.00706456
GSTZ1 glutathione S-transferase zeta 1 -0.00706238
FGFR3 fibroblast growth factor receptor 3 -0.00704354
MMD monocyte to macrophage differentiation-associated -0.00699844
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00698919
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00694729
PID1 phosphotyrosine interaction domain containing 1 -0.0069329
KLHDC2 kelch domain containing 2 -0.00692363
NPEPL1 aminopeptidase-like 1 -0.00688939
DMBT1 deleted in malignant brain tumors 1 -0.00683005
BRCA1 breast cancer 1, early onset -0.00682613
FXYD2 FXYD domain containing ion transport regulator 2 -0.00682217
DUSP22 dual specificity phosphatase 22 -0.00675698
CDC7 cell division cycle 7 -0.00675114
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00674176
DLK1 delta-like 1 homolog (Drosophila) -0.00673139
DES desmin -0.00670062
MLXIP MLX interacting protein -0.00668727
HBZ hemoglobin, zeta -0.00662202
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00660999
PITX3 paired-like homeodomain 3 -0.00660436
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00659989
NUP88 nucleoporin 88kDa -0.00657944
KNTC1 kinetochore associated 1 -0.00656914
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00655476
PFKL phosphofructokinase, liver -0.00654475
MTCH2 mitochondrial carrier 2 -0.00653635
PHYH phytanoyl-CoA 2-hydroxylase -0.00650073
WASHC3 WASH complex subunit 3 -0.00647338
SMTN smoothelin -0.00645843
DYNLL1 dynein, light chain, LC8-type 1 -0.00645113
DPYSL2 dihydropyrimidinase-like 2 -0.0064183
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00633505
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00633309
AXL AXL receptor tyrosine kinase -0.00632625
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00630707
AKAP7 A kinase (PRKA) anchor protein 7 -0.00630042
CD69 CD69 molecule -0.00629958
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00629745
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.00628866
LXN latexin -0.00627546
PDGFC platelet derived growth factor C -0.00624385
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00623304
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00623236
PBLD phenazine biosynthesis-like protein domain containing -0.00622556
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00621787
ISG15 ISG15 ubiquitin-like modifier -0.0062124
STEAP3 STEAP family member 3, metalloreductase -0.00620711
PSD3 pleckstrin and Sec7 domain containing 3 -0.00617561
TRIB2 tribbles pseudokinase 2 -0.00617129
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00617041
REXO5 RNA exonuclease 5 -0.00615884
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00615237
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00612928
NMU neuromedin U -0.00611977
MDM1 Mdm1 nuclear protein homolog (mouse) -0.00611408
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0061091
CIT citron rho-interacting serine/threonine kinase -0.00609673
EPCAM epithelial cell adhesion molecule -0.00608351
ACADVL acyl-CoA dehydrogenase, very long chain -0.0060577
HAMP hepcidin antimicrobial peptide -0.00602798
PDLIM4 PDZ and LIM domain 4 -0.00602406
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00601493
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00600799
SFXN3 sideroflexin 3 -0.00598976
RGS10 regulator of G-protein signaling 10 -0.00597702
TYMS thymidylate synthetase -0.00596015
FKBP3 FK506 binding protein 3, 25kDa -0.00585828
PFKP phosphofructokinase, platelet -0.00585456
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00583149
DUSP1 dual specificity phosphatase 1 -0.00583061
TM7SF2 transmembrane 7 superfamily member 2 -0.00580076
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00578192
LETMD1 LETM1 domain containing 1 -0.00578003
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.00576571
SPTBN2 spectrin, beta, non-erythrocytic 2 -0.00576337
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00576124
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00573421
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -0.00572604
TTC3 tetratricopeptide repeat domain 3 -0.00572276
PASK PAS domain containing serine/threonine kinase -0.00571741
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00571284
DPY19L2P2 DPY19L2 pseudogene 2 -0.00570622
PPP1R7 protein phosphatase 1, regulatory subunit 7 -0.0056852
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00567868
CFP complement factor properdin -0.00566762
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00565881
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00564682
FADS1 fatty acid desaturase 1 -0.0056364
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.00562516
CD180 CD180 molecule -0.00562025
SUMO3 small ubiquitin-like modifier 3 -0.00561336
SFTPA2 surfactant protein A2 -0.00560335
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00558707
LTF lactotransferrin -0.00557533
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00555883
MDK midkine (neurite growth-promoting factor 2) -0.00554004
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00553783
C21ORF33 chromosome 21 open reading frame 33 -0.00553546
C3ORF14 chromosome 3 open reading frame 14 -0.00552409
NCOR2 nuclear receptor corepressor 2 -0.00552073
CBY1 chibby homolog 1 (Drosophila) -0.00551925
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00550668
ITPK1 inositol-tetrakisphosphate 1-kinase -0.00550605
MGP matrix Gla protein -0.00550426
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00550031
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.00547064
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00544078
CHEK2 checkpoint kinase 2 -0.00543634
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -0.00543409
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.0054283
HIP1R huntingtin interacting protein 1 related -0.00542147
RFK riboflavin kinase -0.00540619
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -0.00538994
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -0.00537263
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.00536152
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00535477
CCND2 cyclin D2 -0.0053398
REG1B regenerating islet-derived 1 beta -0.0053386
NPAS2 neuronal PAS domain protein 2 -0.00533695
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00532631
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00532127
CHKB choline kinase beta -0.00531999
KIAA1644 KIAA1644 -0.00531674
HPCAL1 hippocalcin-like 1 -0.0053142
RNASEH2A ribonuclease H2, subunit A -0.00531086
RBBP8 retinoblastoma binding protein 8 -0.00528406
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00528115
DENR density-regulated protein -0.00527897
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -0.00527247
CRYM crystallin, mu -0.00526358
MAMLD1 mastermind-like domain containing 1 -0.00526179
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00525706
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00524985
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00524805
CHAF1B chromatin assembly factor 1, subunit B (p60) -0.00524651
TSPAN4 tetraspanin 4 -0.00524361
PYGL phosphorylase, glycogen, liver -0.0052312
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00522383
RTN4 reticulon 4 -0.0052111
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00520135
SNAI2 snail family zinc finger 2 -0.00519803
PCYOX1L prenylcysteine oxidase 1 like -0.00519797
GALC galactosylceramidase -0.00519718
NOL4 nucleolar protein 4 -0.00518335
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.00517803
SELENOW selenoprotein W -0.00517048
CRY1 cryptochrome circadian clock 1 -0.00516779
KLK1 kallikrein 1 -0.00516721
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00516619
TRMT5 tRNA methyltransferase 5 -0.00516377
MSLN mesothelin -0.00515256
CCNA2 cyclin A2 -0.00514855
SLC38A10 solute carrier family 38, member 10 -0.0051417
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00513858
NEFM neurofilament, medium polypeptide -0.00513035
KRT10 keratin 10, type I -0.00511763
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00510717
CCDC88A coiled-coil domain containing 88A -0.00510465
IFI35 interferon-induced protein 35 -0.00510334
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00509163
CLDN1 claudin 1 -0.00508334
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00507585
RELN reelin -0.0050728
DCT dopachrome tautomerase -0.00505837
SNX6 sorting nexin 6 -0.00505732
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -0.00505731
CRYL1 crystallin, lambda 1 -0.0050525
DGKZ diacylglycerol kinase, zeta -0.00505113
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00504935
OXA1L oxidase (cytochrome c) assembly 1-like -0.00504877
TXNDC9 thioredoxin domain containing 9 -0.00503067
INHBA inhibin, beta A -0.00502821
MARCKSL1 MARCKS-like 1 -0.00502283
SCO2 SCO2 cytochrome c oxidase assembly protein -0.00502018
POLE polymerase (DNA directed), epsilon, catalytic subunit -0.00501461
PRKCB protein kinase C, beta -0.00501429
PDLIM3 PDZ and LIM domain 3 -0.00500075
STK25 serine/threonine kinase 25 -0.00499561
PHACTR1 phosphatase and actin regulator 1 -0.00498268
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00497703
DNM1L dynamin 1-like -0.00497643
NPC2 Niemann-Pick disease, type C2 -0.00497635
CDT1 chromatin licensing and DNA replication factor 1 -0.00497129
COTL1 coactosin-like F-actin binding protein 1 -0.0049662
MPST mercaptopyruvate sulfurtransferase -0.0049596
CEP170 centrosomal protein 170kDa -0.00495618
ITPKA inositol-trisphosphate 3-kinase A -0.00494544
CEL carboxyl ester lipase -0.00494037
VCX2 variable charge, X-linked 2 -0.00493604
SPA17 sperm autoantigenic protein 17 -0.00491745
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.00491173
TGFA transforming growth factor, alpha -0.00490716
CNN1 calponin 1, basic, smooth muscle -0.00489885
TUBB3 tubulin, beta 3 class III -0.00489801
CCNI cyclin I -0.00488797
SMC1A structural maintenance of chromosomes 1A -0.004884
MAP2K2 mitogen-activated protein kinase kinase 2 -0.00487758
NBAS neuroblastoma amplified sequence -0.00487633
MPHOSPH9 M-phase phosphoprotein 9 -0.00487072