LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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111 proteins differentially phosphorylated following the LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARGLU1 arginine and glutamate rich 1
ARHGAP30 Rho GTPase activating protein 30
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
AZI2 5-azacytidine induced 2
BCLAF1 BCL2-associated transcription factor 1
BIRC6 baculoviral IAP repeat containing 6
CANX calnexin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CCNL1 cyclin L1
CDK12 cyclin-dependent kinase 12
CHD4 chromodomain helicase DNA binding protein 4
CHKA choline kinase alpha
CIT citron rho-interacting serine/threonine kinase
CLNS1A chloride channel, nucleotide-sensitive, 1A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF4B eukaryotic translation initiation factor 4B
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5B eukaryotic translation initiation factor 5B
EPS15 epidermal growth factor receptor pathway substrate 15
ERCC6L excision repair cross-complementation group 6-like
FAM76B family with sequence similarity 76, member B
FKBP15 FK506 binding protein 15, 133kDa
FNBP4 formin binding protein 4
FTH1 ferritin, heavy polypeptide 1
GNL1 guanine nucleotide binding protein-like 1
GPATCH2 G patch domain containing 2
GTPBP1 GTP binding protein 1
HIPK1 homeodomain interacting protein kinase 1
HIST1H1B histone cluster 1, H1b
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HP1BP3 heterochromatin protein 1, binding protein 3
HTATSF1 HIV-1 Tat specific factor 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KNOP1 lysine-rich nucleolar protein 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
LARP1 La ribonucleoprotein domain family, member 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP4 microtubule-associated protein 4
MCM2 minichromosome maintenance complex component 2
MED24 mediator complex subunit 24
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTA3 metastasis associated 1 family, member 3
MYH9 myosin, heavy chain 9, non-muscle
NCL nucleolin
NDRG2 NDRG family member 2
NEK3 NIMA-related kinase 3
NIPBL Nipped-B homolog (Drosophila)
NKAP NFKB activating protein
NOP56 NOP56 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NVL nuclear VCP-like
PA2G4 proliferation-associated 2G4, 38kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDIA6 protein disulfide isomerase family A, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PGK1 phosphoglycerate kinase 1
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPAN peter pan homolog (Drosophila)
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRRC2A proline-rich coiled-coil 2A
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
RBM10 RNA binding motif protein 10
RBM19 RNA binding motif protein 19
RIPK2 receptor-interacting serine-threonine kinase 2
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
SDE2 SDE2 telomere maintenance homolog (S. pombe)
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
SRSF11 serine/arginine-rich splicing factor 11
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
TFDP1 transcription factor Dp-1
TFG TRK-fused gene
UBA2 ubiquitin-like modifier activating enzyme 2
WDR26 WD repeat domain 26
WEE1 WEE1 G2 checkpoint kinase
YBX3 Y box binding protein 3
YTHDC1 YTH domain containing 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK

decreased phosphorylation

Symbol Name
AGPS alkylglycerone phosphate synthase
AHNAK2 AHNAK nucleoprotein 2
C7ORF50 chromosome 7 open reading frame 50
C9ORF114 chromosome 9 open reading frame 114
CUL3 cullin 3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLM1 golgi membrane protein 1
KIAA1715 KIAA1715
NRBF2 nuclear receptor binding factor 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
TMEM87B transmembrane protein 87B
ZW10 zw10 kinetochore protein