LS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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Genes

117 proteins differentially phosphorylated following the LS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACACA acetyl-CoA carboxylase alpha
ARHGAP30 Rho GTPase activating protein 30
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
AZI2 5-azacytidine induced 2
BRD2 bromodomain containing 2
BYSL bystin-like
CANX calnexin
CCNL1 cyclin L1
CDK12 cyclin-dependent kinase 12
CHD1 chromodomain helicase DNA binding protein 1
CHD4 chromodomain helicase DNA binding protein 4
CHKA choline kinase alpha
CIT citron rho-interacting serine/threonine kinase
CLNS1A chloride channel, nucleotide-sensitive, 1A
CTR9 CTR9, Paf1/RNA polymerase II complex component
CTTNBP2NL CTTNBP2 N-terminal like
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF4B eukaryotic translation initiation factor 4B
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5B eukaryotic translation initiation factor 5B
EPS15 epidermal growth factor receptor pathway substrate 15
ERCC6L excision repair cross-complementation group 6-like
FAM207A family with sequence similarity 207, member A
FKBP15 FK506 binding protein 15, 133kDa
FTH1 ferritin, heavy polypeptide 1
GNL1 guanine nucleotide binding protein-like 1
GPATCH2 G patch domain containing 2
GTPBP1 GTP binding protein 1
HIPK1 homeodomain interacting protein kinase 1
HIST1H1B histone cluster 1, H1b
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HTATSF1 HIV-1 Tat specific factor 1
JUN jun proto-oncogene
KIAA0226 KIAA0226
KIAA1522 KIAA1522
KIAA1715 KIAA1715
KPNA3 karyopherin alpha 3 (importin alpha 4)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP4 microtubule-associated protein 4
MCM2 minichromosome maintenance complex component 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTA3 metastasis associated 1 family, member 3
MTBP MDM2 binding protein
MTDH metadherin
MYH9 myosin, heavy chain 9, non-muscle
NCL nucleolin
NDRG2 NDRG family member 2
NEK3 NIMA-related kinase 3
NKAP NFKB activating protein
NOP56 NOP56 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRBF2 nuclear receptor binding factor 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PA2G4 proliferation-associated 2G4, 38kDa
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDIA6 protein disulfide isomerase family A, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PGK1 phosphoglycerate kinase 1
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRRC2A proline-rich coiled-coil 2A
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
REPS1 RALBP1 associated Eps domain containing 1
RIPK2 receptor-interacting serine-threonine kinase 2
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RPL30 ribosomal protein L30
RPLP2 ribosomal protein, large, P2
RPS6 ribosomal protein S6
RTN4 reticulon 4
SDE2 SDE2 telomere maintenance homolog (S. pombe)
SET SET nuclear proto-oncogene
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
SRSF11 serine/arginine-rich splicing factor 11
STK3 serine/threonine kinase 3
STMN1 stathmin 1
STRN3 striatin, calmodulin binding protein 3
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEX264 testis expressed 264
TFDP1 transcription factor Dp-1
TFG TRK-fused gene
TMEM87A transmembrane protein 87A
TMX1 thioredoxin-related transmembrane protein 1
TRIM28 tripartite motif containing 28
WDR26 WD repeat domain 26
WEE1 WEE1 G2 checkpoint kinase
YBX3 Y box binding protein 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFC3H1 zinc finger, C3H1-type containing
ZRANB2 zinc finger, RAN-binding domain containing 2
ZW10 zw10 kinetochore protein

decreased phosphorylation

Symbol Name
AGPS alkylglycerone phosphate synthase
AHNAK2 AHNAK nucleoprotein 2
ARGLU1 arginine and glutamate rich 1
C7ORF50 chromosome 7 open reading frame 50
C9ORF114 chromosome 9 open reading frame 114
CUL3 cullin 3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLM1 golgi membrane protein 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
TMEM87B transmembrane protein 87B
UBA2 ubiquitin-like modifier activating enzyme 2