LTBR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description lymphotoxin beta receptor (TNFR superfamily, member 3)|This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 4055)
External Link https://ncbi.nlm.nih.gov/gene/4055
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Genes

498 genes differentially expressed following the LTBR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0265079
COG7 component of oligomeric golgi complex 7 0.0193201
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0163043
ANXA3 annexin A3 0.0153676
CCNG1 cyclin G1 0.0153304
IFI27 interferon, alpha-inducible protein 27 0.0143733
AKAP12 A kinase (PRKA) anchor protein 12 0.0139709
MYBPC1 myosin binding protein C, slow type 0.0135476
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0133173
ISG15 ISG15 ubiquitin-like modifier 0.0131537
MECOM MDS1 and EVI1 complex locus 0.0128419
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.0125165
TNNC1 troponin C type 1 (slow) 0.0122563
FXYD3 FXYD domain containing ion transport regulator 3 0.0122018
STXBP2 syntaxin binding protein 2 0.0121527
MSMB microseminoprotein, beta- 0.0119688
GYPC glycophorin C (Gerbich blood group) 0.0118738
SFRP1 secreted frizzled-related protein 1 0.0117626
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0116552
RSL1D1 ribosomal L1 domain containing 1 0.0116364
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.0115532
ACTN2 actinin, alpha 2 0.0115423
FABP4 fatty acid binding protein 4, adipocyte 0.0113437
CCND1 cyclin D1 0.0112913
IFI44L interferon-induced protein 44-like 0.0112693
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0111203
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0111179
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.0110951
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0110881
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.011066
KRT13 keratin 13, type I 0.0109615
GNAS GNAS complex locus 0.0109199
NIBAN1 niban apoptosis regulator 1 0.0108456
RGS10 regulator of G-protein signaling 10 0.0105721
CADM1 cell adhesion molecule 1 0.0105087
MAL mal, T-cell differentiation protein 0.0104584
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0103767
ELOVL2 ELOVL fatty acid elongase 2 0.0103505
WFDC2 WAP four-disulfide core domain 2 0.0101966
C6ORF48 chromosome 6 open reading frame 48 0.0101754
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.0101262
LITAF lipopolysaccharide-induced TNF factor 0.010051
GPX1 glutathione peroxidase 1 0.0100404
MUC16 mucin 16, cell surface associated 0.00999243
ANXA1 annexin A1 0.00984693
CXCL8 chemokine (C-X-C motif) ligand 8 0.00974293
MOXD1 monooxygenase, DBH-like 1 0.00964892
FGF13 fibroblast growth factor 13 0.00964891
GREB1 growth regulation by estrogen in breast cancer 1 0.00953435
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00952668
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00948925
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.0094467
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00944386
MAGT1 magnesium transporter 1 0.00939134
RTN2 reticulon 2 0.00937021
RPL36 ribosomal protein L36 0.00936526
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00924356
PADI2 peptidyl arginine deiminase, type II 0.00922254
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00922069
STOM stomatin 0.00920911
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00920486
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00919316
GDE1 glycerophosphodiester phosphodiesterase 1 0.00917417
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00915384
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00911412
NRN1 neuritin 1 0.00910588
SNAP25 synaptosomal-associated protein, 25kDa 0.00908455
RPL26 ribosomal protein L26 0.00908239
ISG20 interferon stimulated exonuclease gene 20kDa 0.00906493
COL21A1 collagen, type XXI, alpha 1 0.00904839
PEG3 paternally expressed 3 0.00903584
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00903491
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00902628
WBP5 WW domain binding protein 5 0.0090209
FGF9 fibroblast growth factor 9 0.00898216
BST2 bone marrow stromal cell antigen 2 0.00897402
RPS14P3 ribosomal protein S14 pseudogene 3 0.00893769
WIF1 WNT inhibitory factor 1 0.00893436
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00891089
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00887758
BTG3 BTG family, member 3 0.00882572
ABLIM1 actin binding LIM protein 1 0.00881984
TTN titin 0.0087718
IFITM3 interferon induced transmembrane protein 3 0.00876566
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00876051
BFAR bifunctional apoptosis regulator 0.00875026
TAGLN2 transgelin 2 0.00873747
RNF130 ring finger protein 130 0.00869599
FOLR1 folate receptor 1 (adult) 0.00867015
AK4 adenylate kinase 4 0.00865745
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00863965
S100A7 S100 calcium binding protein A7 0.00862647
IFITM1 interferon induced transmembrane protein 1 0.00860775
LDB3 LIM domain binding 3 0.00851151
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00850838
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0084868
GPC3 glypican 3 0.00847263
PGC progastricsin (pepsinogen C) 0.00844946
SRPX2 sushi-repeat containing protein, X-linked 2 0.00843981
ZNF277 zinc finger protein 277 0.00841718
TPBG trophoblast glycoprotein 0.00838655
YIPF5 Yip1 domain family, member 5 0.00837147
C3 complement component 3 0.0083434
SYT1 synaptotagmin I 0.00832606
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00831279
DEFB1 defensin, beta 1 0.00828888
NDN necdin, melanoma antigen (MAGE) family member 0.00824843
SMPX small muscle protein, X-linked 0.00819855
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00817632
VLDLR very low density lipoprotein receptor 0.00814378
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00812552
PLIN3 perilipin 3 0.00811363
PRMT1 protein arginine methyltransferase 1 0.00809662
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0080913
TPM4 tropomyosin 4 0.00805534
ANXA2P2 annexin A2 pseudogene 2 0.00804086
PSAT1 phosphoserine aminotransferase 1 0.00802396
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.0080153
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00800139
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.00796469
IL32 interleukin 32 0.00793628
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00792356
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00789393
MX2 MX dynamin-like GTPase 2 0.007889
FAM171A1 family with sequence similarity 171, member A1 0.00788737
TSPYL5 TSPY-like 5 0.00788572
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0078673
B2M beta-2-microglobulin 0.00784233
OXA1L oxidase (cytochrome c) assembly 1-like 0.00781188
SGK1 serum/glucocorticoid regulated kinase 1 0.00776445
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00776028
DAZAP2 DAZ associated protein 2 0.00773372
SELL selectin L 0.00773175
EIF4B eukaryotic translation initiation factor 4B 0.00772778
DAXX death-domain associated protein 0.00771228
IL6 interleukin 6 0.00770376
EDN3 endothelin 3 0.00769069
FHL1 four and a half LIM domains 1 0.00768468
ANXA5 annexin A5 0.00766614
POPDC3 popeye domain containing 3 0.00760342
RFC2 replication factor C (activator 1) 2, 40kDa 0.00760065
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00759891
EIF3E eukaryotic translation initiation factor 3, subunit E 0.00757074
MFAP5 microfibrillar associated protein 5 0.00757003
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.00754099
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00749506
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00744421
PRKCQ protein kinase C, theta 0.00743803
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00743773
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00743435
ZNF467 zinc finger protein 467 0.00742545
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 0.00742334
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00742149
SYNGR2 synaptogyrin 2 0.00741509
CRABP1 cellular retinoic acid binding protein 1 0.00741039
SPARCL1 SPARC-like 1 (hevin) 0.00739001
MYO1C myosin IC 0.00738773
IRF8 interferon regulatory factor 8 0.00736222
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00735882
CAPNS1 calpain, small subunit 1 0.00729635
MYOZ2 myozenin 2 0.0072824
STMN2 stathmin 2 0.00728045
MRPL33 mitochondrial ribosomal protein L33 0.00727579
CNN2 calponin 2 0.00726889
ODAM odontogenic, ameloblast asssociated 0.00726823
MRPS33 mitochondrial ribosomal protein S33 0.00726628
NCOA4 nuclear receptor coactivator 4 0.0072655
MSX1 msh homeobox 1 0.00726545
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.00724895
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00724421
JPT2 Jupiter microtubule associated homolog 2 0.00723081
FPGS folylpolyglutamate synthase 0.00721592
PTCH1 patched 1 0.00721513
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00721222
SP110 SP110 nuclear body protein 0.00720869
RPP40 ribonuclease P/MRP 40kDa subunit 0.0071881
IL6ST interleukin 6 signal transducer 0.00717943
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00717464
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00717328
CD48 CD48 molecule 0.00715935
TNNC2 troponin C type 2 (fast) 0.00714548
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00714014
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00713795
TNNI1 troponin I type 1 (skeletal, slow) 0.00713538
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00712849
TSPAN1 tetraspanin 1 0.00712776
FABP7 fatty acid binding protein 7, brain 0.00712084
TPM3 tropomyosin 3 0.00711719
NOP16 NOP16 nucleolar protein 0.00711545
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00711
ZBTB38 zinc finger and BTB domain containing 38 0.00710619
ASRGL1 asparaginase like 1 0.00709576
CPVL carboxypeptidase, vitellogenic-like 0.00708722
SHCBP1 SHC SH2-domain binding protein 1 0.00708641
MDFIC MyoD family inhibitor domain containing 0.00705665
PTGES prostaglandin E synthase 0.00705623
ALCAM activated leukocyte cell adhesion molecule 0.00703607
PDE4B phosphodiesterase 4B, cAMP-specific 0.00702417
MT1E metallothionein 1E 0.00700276
IRS2 insulin receptor substrate 2 0.00700216
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00699757
C9ORF91 chromosome 9 open reading frame 91 0.00697977
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00697122
HMOX2 heme oxygenase 2 0.00695937
MPHOSPH8 M-phase phosphoprotein 8 0.0069583
TWF2 twinfilin actin binding protein 2 0.0069361
PTK2 protein tyrosine kinase 2 0.00693085
GPR137B G protein-coupled receptor 137B 0.00692898
SLC35G2 solute carrier family 35, member G2 0.00692553
ADGRE1 adhesion G protein-coupled receptor E1 0.0069188
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0069114
SRPRB signal recognition particle receptor, B subunit 0.00690121
MED6 mediator complex subunit 6 0.00689443
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00688786
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.00688567
OPHN1 oligophrenin 1 0.00686841
SOX17 SRY (sex determining region Y)-box 17 0.00686399
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.0068467
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00684415
ZNF652 zinc finger protein 652 0.00684306
TNIP1 TNFAIP3 interacting protein 1 0.00683619
SAMHD1 SAM domain and HD domain 1 0.00683372
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.00682644
ZMAT3 zinc finger, matrin-type 3 0.0068203
TLR4 toll-like receptor 4 0.00681697
GTPBP8 GTP-binding protein 8 (putative) 0.00681039
IFI16 interferon, gamma-inducible protein 16 0.00680206
CAPG capping protein (actin filament), gelsolin-like 0.00679192
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00678927
HLA-B major histocompatibility complex, class I, B 0.00678672
NANS N-acetylneuraminic acid synthase 0.00678086
STATH statherin 0.00677653
ACTA1 actin, alpha 1, skeletal muscle 0.00676689
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00676669
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00676185
RGCC regulator of cell cycle 0.00675393
YIPF6 Yip1 domain family, member 6 0.00674601
TAC1 tachykinin, precursor 1 0.00673156
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00672491
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00672453
RPL35 ribosomal protein L35 0.006713
LOXL2 lysyl oxidase-like 2 0.00670976
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00670423
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00670412
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00669198
MAGED2 melanoma antigen family D2 0.00668058
LY96 lymphocyte antigen 96 0.00665913
FNBP1 formin binding protein 1 0.00664879
PDZD2 PDZ domain containing 2 0.00664304
AKAP8 A kinase (PRKA) anchor protein 8 0.00662785

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0345329
MAP7 microtubule-associated protein 7 -0.025984
CHIC2 cysteine-rich hydrophobic domain 2 -0.0172696
CDC20 cell division cycle 20 -0.0172147
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0169877
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0169627
ALOX5 arachidonate 5-lipoxygenase -0.0145645
CTSZ cathepsin Z -0.0144594
MZB1 marginal zone B and B1 cell-specific protein -0.0135779
ANPEP alanyl (membrane) aminopeptidase -0.0129496
BGN biglycan -0.0129349
WDR7 WD repeat domain 7 -0.0124443
AEBP1 AE binding protein 1 -0.0122579
POU2AF1 POU class 2 associating factor 1 -0.0116211
CPA3 carboxypeptidase A3 (mast cell) -0.0113675
TPSAB1 tryptase alpha/beta 1 -0.0111851
SLC38A1 solute carrier family 38, member 1 -0.0108951
HEPH hephaestin -0.0108803
TMEM176B transmembrane protein 176B -0.0105767
ADIRF adipogenesis regulatory factor -0.010426
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0103593
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0103549
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0103066
TXLNA taxilin alpha -0.0102868
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0102854
STK26 serine/threonine protein kinase 26 -0.0102627
SCRG1 stimulator of chondrogenesis 1 -0.010238
TDO2 tryptophan 2,3-dioxygenase -0.0102349
PCDH9 protocadherin 9 -0.0102091
CPB1 carboxypeptidase B1 (tissue) -0.0102034
PTK2B protein tyrosine kinase 2 beta -0.010148
OLFM4 olfactomedin 4 -0.0101278
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0101098
AKR1C3 aldo-keto reductase family 1, member C3 -0.0100354
SOX9 SRY (sex determining region Y)-box 9 -0.00999062
MMP9 matrix metallopeptidase 9 -0.00992487
ZBTB18 zinc finger and BTB domain containing 18 -0.00989618
C1QB complement component 1, q subcomponent, B chain -0.00985969
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00984708
FGFR3 fibroblast growth factor receptor 3 -0.00978614
PRSS3 protease, serine, 3 -0.00975323
VEGFA vascular endothelial growth factor A -0.00974655
RAPSN receptor-associated protein of the synapse -0.0096843
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00960749
VNN1 vanin 1 -0.00957513
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00943118
COMP cartilage oligomeric matrix protein -0.00939434
NOTCH2 notch 2 -0.00936821
GLOD4 glyoxalase domain containing 4 -0.00936723
LEF1 lymphoid enhancer-binding factor 1 -0.00932265
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00931149
CA12 carbonic anhydrase XII -0.00927897
ITGA8 integrin, alpha 8 -0.009253
HMGB2 high mobility group box 2 -0.00920999
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00915904
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00909352
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00906204
RRAGA Ras-related GTP binding A -0.00893074
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00889904
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0088638
CBX5 chromobox homolog 5 -0.00881769
VCAM1 vascular cell adhesion molecule 1 -0.00879791
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00874935
KRT14 keratin 14, type I -0.00872193
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00866392
CD9 CD9 molecule -0.00865049
NMU neuromedin U -0.00855952
S100A4 S100 calcium binding protein A4 -0.00850649
IGFBP1 insulin-like growth factor binding protein 1 -0.00849019
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00845066
RAB8A RAB8A, member RAS oncogene family -0.00841948
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00836135
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00832423
CCL19 chemokine (C-C motif) ligand 19 -0.00830782
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00830427
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00830362
ENG endoglin -0.00828617
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00822628
NNMT nicotinamide N-methyltransferase -0.00821425
MTCL1 microtubule crosslinking factor 1 -0.00821399
MGAM maltase-glucoamylase -0.00819105
NID2 nidogen 2 (osteonidogen) -0.00815536
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00813949
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00811458
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00809127
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00808266
BAHCC1 BAH domain and coiled-coil containing 1 -0.00807566
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00805693
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00805564
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -0.00805143
PKP1 plakophilin 1 -0.0080166
GOLIM4 golgi integral membrane protein 4 -0.00800333
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00798115
GUSB glucuronidase, beta -0.00795934
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00795788
PCP4 Purkinje cell protein 4 -0.00795697
CLC Charcot-Leyden crystal galectin -0.00795582
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00795363
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00791253
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00789989
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00787917
NTS neurotensin -0.00785426
PRKCI protein kinase C, iota -0.00782474
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00779393
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00778821
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00778617
GPSM2 G-protein signaling modulator 2 -0.00776752
PSD3 pleckstrin and Sec7 domain containing 3 -0.00776488
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.00774355
EML3 echinoderm microtubule associated protein like 3 -0.00773668
SMAD7 SMAD family member 7 -0.00769845
NBPF10 neuroblastoma breakpoint family, member 10 -0.00768328
KLHDC2 kelch domain containing 2 -0.00767031
ENAH enabled homolog (Drosophila) -0.00766973
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00764665
ELN elastin -0.00764431
KANK1 KN motif and ankyrin repeat domains 1 -0.00760028
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.0075887
S100A8 S100 calcium binding protein A8 -0.00751801
SCGB2A2 secretoglobin, family 2A, member 2 -0.00750543
TGFB3 transforming growth factor, beta 3 -0.00749788
SEPP1 selenoprotein P, plasma, 1 -0.00748636
NDRG1 N-myc downstream regulated 1 -0.00747911
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00747698
CD38 CD38 molecule -0.00745792
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00744857
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00744165
MAGEA3 melanoma antigen family A3 -0.00743952
PERP PERP, TP53 apoptosis effector -0.0074072
PID1 phosphotyrosine interaction domain containing 1 -0.00740348
RTN3 reticulon 3 -0.00738941
H2AX H2A.X variant histone -0.00738478
NECTIN3 nectin cell adhesion molecule 3 -0.00738144
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00737472
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00734459
HMGB3 high mobility group box 3 -0.00733841
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00733452
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00733213
SEH1L SEH1-like (S. cerevisiae) -0.00732645
RTN1 reticulon 1 -0.00731922
ANGPT1 angiopoietin 1 -0.00730825
C2CD5 C2 calcium-dependent domain containing 5 -0.00728717
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00728709
WT1 Wilms tumor 1 -0.00727699
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00726627
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.00725595
ZNF329 zinc finger protein 329 -0.00723549
MPRIP myosin phosphatase Rho interacting protein -0.00722153
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00721706
INTS1 integrator complex subunit 1 -0.00721399
RCAN2 regulator of calcineurin 2 -0.00718694
RANGAP1 Ran GTPase activating protein 1 -0.00717659
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.00717473
MYO1D myosin ID -0.00714566
ARHGAP22 Rho GTPase activating protein 22 -0.00714322
HIP1R huntingtin interacting protein 1 related -0.0071377
XYLT1 xylosyltransferase I -0.00712719
RNF19B ring finger protein 19B -0.00708596
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00708226
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00708162
QPCT glutaminyl-peptide cyclotransferase -0.00706138
DPYSL2 dihydropyrimidinase-like 2 -0.00703758
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00702599
TMEM176A transmembrane protein 176A -0.00701648
GRAMD4 GRAM domain containing 4 -0.00701596
SNAI2 snail family zinc finger 2 -0.00699481
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00697453
ANGPTL2 angiopoietin-like 2 -0.00696638
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.006951
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.0069453
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.00694089
C11ORF71 chromosome 11 open reading frame 71 -0.00693678
CHD1L chromodomain helicase DNA binding protein 1-like -0.00693508
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00691396
CYBB cytochrome b-245, beta polypeptide -0.00690577
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00690133
GATAD2A GATA zinc finger domain containing 2A -0.00689898
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0068842
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00687792
CD209 CD209 molecule -0.0068774
SATB2 SATB homeobox 2 -0.0068752
MFAP3L microfibrillar-associated protein 3-like -0.0068719
MAEA macrophage erythroblast attacher -0.00686948
PDGFC platelet derived growth factor C -0.00686832
SIRT3 sirtuin 3 -0.00686785
PLPP3 phospholipid phosphatase 3 -0.00686405
CD1E CD1e molecule -0.00685509
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00684851
MED13L mediator complex subunit 13-like -0.0068408
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00683443
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00683394
FST follistatin -0.00682135
DHRS1 dehydrogenase/reductase (SDR family) member 1 -0.00681877
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.00681728
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00681436
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -0.00681082
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -0.00680647
FIP1L1 factor interacting with PAPOLA and CPSF1 -0.00680093
SRPK2 SRSF protein kinase 2 -0.00679917
JAG1 jagged 1 -0.00679157
SMC1A structural maintenance of chromosomes 1A -0.00678909
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00678418
REG1B regenerating islet-derived 1 beta -0.00677797
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00677487
FEM1B fem-1 homolog b (C. elegans) -0.00676561
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00676449
HTRA1 HtrA serine peptidase 1 -0.00673868
RRBP1 ribosome binding protein 1 -0.00671209
PCOLCE procollagen C-endopeptidase enhancer -0.00668602
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00667681
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00666976
PDLIM4 PDZ and LIM domain 4 -0.00666844
MARCHF6 membrane associated ring-CH-type finger 6 -0.00665582
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 -0.00663906
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00660524
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00658439
IPO9 importin 9 -0.00658213
TARDBP TAR DNA binding protein -0.00657236
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.00656903
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00656835
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00655436
GAS6 growth arrest-specific 6 -0.00653557
MFSD10 major facilitator superfamily domain containing 10 -0.00652244
ACAA2 acetyl-CoA acyltransferase 2 -0.00652228
LMNB2 lamin B2 -0.00650725
ITPRID2 ITPR interacting domain containing 2 -0.00649179
EPS15 epidermal growth factor receptor pathway substrate 15 -0.00648638
CCDC92 coiled-coil domain containing 92 -0.00648428
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00646542
TSPO translocator protein (18kDa) -0.00646064
KIAA0930 KIAA0930 -0.00644443
STEAP3 STEAP family member 3, metalloreductase -0.00644079
CCNF cyclin F -0.0064393
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00643518
SAFB scaffold attachment factor B -0.00641051
KIF13B kinesin family member 13B -0.00640939
CNPY3 canopy FGF signaling regulator 3 -0.00640701
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00640641
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00640378
TENT4A terminal nucleotidyltransferase 4A -0.00639896
FAM193A family with sequence similarity 193, member A -0.0063954
TRIM29 tripartite motif containing 29 -0.00638548
CD79A CD79a molecule, immunoglobulin-associated alpha -0.00638098
CBS cystathionine-beta-synthase -0.00637455
PHF10 PHD finger protein 10 -0.00636761
NOTCH1 notch 1 -0.00635512
MMP1 matrix metallopeptidase 1 -0.00634151
EPHB6 EPH receptor B6 -0.00634062